Um homem de mais ou menos 50 anos, vigoroso, geralmente afetuoso, mas durante seus mais violentos paroxismos apresenta uma tendência a explosões de raiva com marcada excitação nervosa, vem sofrendo nos últimos meses de uma dor violenta na perna direita, depois de um tratamento alopático para um suposto reumatismo (que não foi confirmado) na órbita direita, com medicamentos tópicos. Esta última dor atacou a parte posterior da perna, especialmente da panturrilha até o calcanhar, mas não envolveu o calcanhar ou o tornozelo. O paciente descreve a dor como extremamente aguda, como câimbra, repuxando, freqüentemente interrompida por espetadas de dentro para fora; mas pela manhã, quando a dor era mais suportável, era uma dor como se estivesse machucado. A dor piorava ao entardecer e durante o repouso, especialmente após movimento, enquanto sentado ou de pé, principalmente após ter andado ao ar livre. Enquanto andava, a dor passava da panturrilha direita para o braço esquerdo se ele colocasse a mão no bolso ou no peito e o deixasse imóvel, mas passava tão logo ele movimentasse o braço, e a dor retornava para a panturrilha direita. O maior alívio se dava ao ficar andando no quarto e esfregando a parte dolorida. Os sintomas concomitantes eram insônia antes da meia-noite, ataques recorrentes freqüentes de súbitas ondas de calor ao entardecer com sede sem calafrio prévio, um gosto desagradável de gordura na boca com náusea, e uma dor pressiva quase constante na parte inferior do tórax e epigástrio como se houvesse alguma coisa pressionando de dentro para fora. No skilful homœopathist, who is perfectly familiar with the action of his remedies, will long remain in doubt as to the correct remedy in this case, with so complete and accurate a picture of the disease, for all these symptoms together correspond to a single one, which is thoroughly homœopathic; but the beginner will be obliged to look for nearly every symptom and only after long search will he find the one most fit among the concurrent remedies. Between these two extremes of knowing and not knowing, lie many degrees of partial knowledge, which require a more or less frequent consultation of the book. One person, for example, knows that the pains repeatedly changing from place to place, worse towards evening and during rest, together with the fatty taste in the mouth, the sleeplessness before midnight and others of the symptoms mentioned, belong especially to the action of Pulsatilla, but he is not sure whether the remaining symptoms also belong to it, and he will not, if be acts conscientiously, spare the trouble to compare these latter; but he will soon see that pulsatilla is not the correct homœopathic remedy, because, in addition to the mental symptoms, there are others which are not similar, but, indeed, are directly, contradictory to it. Another person who has studied more the peculiarities of the pains and distinctly remembers that china corresponds to the paralytic and bruised pains as well as to the jerking tearings and the stitches from within outward and to the pains jumping from place to place. In addition, he believes that also symptoms, like sleeplessness before midnight, the aggravation during rest, as well as the relief from motion and rubbing, together with the flushes of heat with thirst, correspond to this drug, but because he does not know he also must consult the books; so he will soon meet with contradictions, just as the previous one did, and he will see clearly the unfitness of china for the case. Neither of these two, however, will think of administering to the patient a remedy whose curative power in this case is so improbable, but as conscientious homœopathic physicians, they will look farther and compare, and by the help of this hand-book they will soon find, without great difficulty, the only really homœopathically indicated remedy. But even a third physician, educated in homœopathy, one who recognizes the contra-indications of pulsatilla, china and other concurrent remedies, does not know sufficiently that VALERIANA corresponds to the chief symptoms, and in order to be perfectly sure about this rather infrequently used remedy, he will quickly look up the few doubtful symptoms, and convince himself that this drug, among all the known medicines, is the best adapted to this case, as was proved in the result; for, after a single very small dose exhibited in a high potency in water, the whole trouble, with all the concomitant symptoms, was completely removed within three days. The half-educated physician, however, who consults only the original sources and discards every sort of repertory will not easily think of looking for this drug, which is seldom used for similar complaints, in the second vol of Archiv., and before doing it, he will expend much time and trouble, which might have been more usefully employed, in comparing other and more frequently used remedies; and if, at last, he should consult it, he will even here meet with difficulties and doubts, which are not easily overcome by the unskilled without other help, since most of the symptoms which must be considered here, must be more or less completed by the characteristics of the remedy, in order to be found suitable, and besides many errors in the notes, many secondary effects which are not marked as such and hence are not easily recognized, increase the uncertainty.