CURRICULUM VITAE
CARLA MARINA PEREIRA GOMES
Personal contact: +351 914914918 | [email protected]
Institutional Adress: Instituto de Engenharia Biomédica (INEB), University of Porto
Rua do Campo Alegre nº 823, 4150-180 Porto, Portugal | Telephone: +351 226074900 | Fax: +351 226094567
Date of birth: 27th of January 1988
Nationality: Portuguese
EDUCATION
Faculty of Engineering, University of Porto, Portugal
PhD Student (PhD Programme in Biomedical Engineering)
“Functionalized nanoparticles for targeted gene delivery to nervous system”
Supervisor: Ana Paula Pêgo, Principal Investigator at INEB, University of Porto
Financed by FCT (SFRH/BD/79930/2011)
Faculty of Sciences and Technology – University of Coimbra, Portugal
Master Programme in Cell and Molecular Biology
“Impact of therapeutic gene silencing on cancer cell lines of different histological
origins”
Supervisors: Prof. João Nuno Moreira, Faculty of Pharmacy, University of
Coimbra and Prof. Maria Conceição Pedroso Lima, Department of Biochemistry,
University of Coimbra
Classification: 18/20
University of Aveiro, Portugal
Degree on Biomedical Sciences, Minor in Molecular Biomedicine
Classification: 17/20
September 2011 till present
September 2009 to July 2011
September 2006 to June 2009
TRAINING AND DEVELOPMENT
Course in Laboratory Animal Science at IBMC, University of Porto, Portugal
(Accreditation as Category C personnel by the Federation of European
Laboratory Animal Science Associations – FELASA)
14-05-2012 – 25-05-2012
Post-Graduate Course entitled “Seeding of nerve cells – Implementation and
characterization 2nd Edition” in iMed.UL, Faculty of Pharmacy, University of
Lisbon, Portugal
06-02-2012 – 10-02-2012
50 hour course of “English for Academic Purposes II” at the Faculty of Letters,
University of Coimbra, with the mark of 17 (out of 20)
01-2010 – 07-2010
CARLA MARINA PEREIRA GOMES
PAGE 2
RESEARCH AND WORK EXPERIENCE
PhD student at NEWTherapies Group, INEB, University of Porto, Portugal
01-01-2012 - present
Master student at Vectors and Gene Therapy Group, Center for
Neurosciences and Cell Biology (CNC), University of Coimbra, Portugal
01-09-2010 – 15-07-2011
Research Trainee at Cytogenetics and Genomics Laboratory,
Faculty of Medicine, University of Coimbra, Portugal
Project: “Cytogenetics and cytogenomics: from chromosomes to the nucleotide”
15-02-2010 – 05-03-2010
Research Trainee at Vectors and Gene Therapy Group, Center for
Neurosciences and Cell Biology (CNC), University of Coimbra, Portugal
Project: “Gene silencing in human breast cancer”
19-10-2009 – 06-11-2009
PARTICIPATION IN RESEARCH PROJECTS
Project: TARGETS - TARgeted GEne Therapy Strategies to treat nerve injury
Participants: Associação para o Desenvolvimento da Faculdade de Ciências
(ADFC/FC/UP), Centro de Neurociências e Biologia Celular (CNBC/UC), Instituto
de Biologia Molecular e Celular (IBMC/UP), Institute for Biophysics - University
of Linz (IB/UL)
Financing Institution: FCT - PTDC/CTM-NAN/115124/2009
01-04-2011 – 30-09-2014
OUTREACH ACTIVITIES
Participation in: ‘10ª Mostra de Ciência, Ensino e Inovação da Universidade do Porto’, 22-25 March, 2012. Porto,
Portugal
Participation in: ‘Noite Europeia dos Investigadores’ as an INEB investigator, 28 September, 2012. Porto, Portugal
PROFESSIONAL MEMBERSHIPS
Member of the European Society for Biomaterials (from 2013)
PUBLICATIONS
Thesis
Master Thesis: ‘Impact of therapeutic gene silencing on cancer cell lines of different histological origins’ (2011)
University of Coimbra, Coimbra, Portugal
CARLA MARINA PEREIRA GOMES
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Papers in peer-reviewed scientific journals:
Gomes CP, Gomes-da-Silva LC, Ramalho JS, de Lima MC, Simões S, Moreira JN. ‘Impact of PLK-1 Silencing on
Endothelial Cells and Cancer Cells of Diverse Histological Origin’. (2013) Curr Gene Ther, 13(3), 189-201 IF: 5.318
Gomes CP, Lopes CDF, Moreno PMD, Varela-Moreira A, Alonso MJ, Pêgo AP. ‘Translating chitosan to clinical
delivery of nucleic acid-based drugs’. (2014) MRS Bulletin 39, 60-70 IF: 5.024
Sadio A, Gustafsson JK, Pereira B, Gomes CP, Hansson GC, David L, Pêgo AP, Almeida R. ‘ModifiedChitosan/siRNA Nanoparticles Downregulate Cellular CDX2 Expression and Cross the Gastric Mucus Barrier’.
(2014) PLoS ONE, 9(6), e99449 IF: 3.730
ORAL COMMUNICATIONS
Gomes C, Silva LG, Fonseca NA, Ramalho JS, Moreira JN. ‘Activity of anti-plk-1 siRNA on cancer cell lines of
different histological origin’. III Congress of the Portuguese Society of Pharmaceutical Sciences and IX SpanishPortuguese Conference on Controlled Drug Delivery, 13-15 October, 2011. Porto, Portugal
Gomes CP, Moreira A, Moreno P, Pêgo AP. ‘Trimethyl Chitosan-Based Nanoparticles for Targeted Gene Delivery
to the Peripheral Nervous System’. 11th International Conference of the European Chitin Society, 5-8 May, 2013.
Porto, Portugal
Gomes CP, Moreira A, Moreno P, Pêgo AP. ‘Trimethyl chitosan as a gene carrier to the peripheral nervous
system’. 25th European Conference on Biomaterials and 10th Young Scientific Forum, 8-12 September, 2013.
Madrid, Spain
Gomes CP, Moreira A, M Gomez-Lazaro, Moreno P, Pêgo AP. ‘Uptake and intracellular localization of TMC-based
nanoparticles assessed by imaging flow cytometry’. International Symposium in Applied Bioimaging – From
Molecule to Man, 3-4 October, 2013. Porto, Portugal
POSTERS IN CONFERENCES
Sadio A, Camilo V, Gomes C, Pires L, David L, Pêgo AP, Almeida R. ‘Downregulation of CDX2 expression in gastric
cells using chitosan/siRNA nanoparticles – A strategy to revert gastric intestinal metaplasia’. XXVth International
Workshop on Helicobacter and related bacteria in chronic digestive inflammation and gastric cancer, 13 – 15
September, 2012. Ljubljana, Slovenia
Sadio A, Camilo V, Gomes C, Pires L, David L, Pêgo AP, Almeida R. ‘Downregulation of CDX2 expression in gastric
cells using chitosan/siRNA nanoparticles – A strategy to revert gastric intestinal metaplasia’. A One Day
Symposium with Carlos Caldas sponsored by EACR, 29 October, 2012. Porto, Portugal
Sadio A, Gomes C, Moreno P, David L, Pêgo AP, Almeida R. ‘Downregulation of CDX2 expression in gastric cells
using chitosan modified with imidazole and trimethylchitosan/siRNA nanoparticles’. 11th International
Conference of the European Chitin Society, 5-8 May, 2013. Porto, Portugal
CARLA MARINA PEREIRA GOMES
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Moreira A, Gomes CP, Moreno P, Pêgo AP. ‘Biodegradation of Trimethyl chitosan-based nanoparticles for gene
delivery’. International Symposium in Applied Bioimaging – From Molecule to Man, 3-4 October, 2013. Porto,
Portugal
LANGUAGES
Portuguese – Native
English – Proficient user (C1)
Spanish – Basic user (A2)