gesq.
l&t
Bras.
rq"):SI-SZ, abr,fun.
2tX)2
Aspectos clinicos e patorfgicos da intoxicagio por sida
corpinifolia (Malvaceae) em ciprinos no Rio crande do sull
Edson M.
colodelr, David Driemeief,Alexandrc-p.
.
Lorettis, EduardoJ. cimenoa,
Sandra D.'Ibaversos, fuidenson L Seitzs e priscila
Zlototnki-G
ABSIBAff.- coloder E.M., tlriemeier D., r.oretti A.p., Gimeno
EJ., Ttaverso s.D., s€itz A.r.. &
P.mz.lclinical and pathorogicar arpe*s of sido.rprrel, pri"oning
l{g*_tc
in goats
in-Rio Grande do sut-le$gtoldnnicos e p"toro6.os
si& cwpiniforia
(Maftnceael em caprinos no Rio Grande do sur .
iliilil;;;-fi
*iit ii nwsldr.
wEtxtrt,*r*nr*
seror
de Patologia veterin{ria,Patologia clinica veterin{ria, Faculdade de Veterin6ria,
rypto
universidade Fderal do Rio Grande do $ul, Av. Bento Gongahes qxil,
cJ(. postal ts(xl4, Forto
Alegre, RS 91540.000, Brazil.
This report includes the c$icaj and-natho,losical studies
nf a [rcosomal 6torag€ disease
whiclr ryontaneouslv occ'rred inthree flLcs ofgias e after
siao*rpiois*ro,
tfte gryfgninant-planr in the paddocrrs where ire animds,r*;-gr"i1[:In
dre owb*""t a
total of25 out of 5l animals rvere atrectert. Fcstflortem examinatian
ias performed on 1l
goats- The disease was experimentally induced
hy dosing so*B;f, ird" caryinifolia-Tbe
plant was administered in nshlria or dried o 3 animals.
!6Ai"t*l;;ialroroeicar dranges
were observed in one goat dosed with sida rlwnbifolia aa
a"firs'ao dap. clinical
signs cf the_ poisoning were ataxia, hypermetria, muscle
tremo|s in the head and
and
disorden ofdeglutition. Theclinical signswere exacerbated
uv*o**.niaftertbe survMng
animals had been moved to other pastures and stopped *o"C
signs were
still observed during 24
Ar necropsy, no,ignin.arrt"gro"s'iJil werc obse.nd.
T".nfu:
Microscopic lesions included various degrees of \rac;on-tr""i"
tfr" Or"Or*rn of neurons
and glial cells. similar leeions were oderved in the acinar p"ncr*ati!-"lrk,
hepatorytes,
*;;;;;
ir
i*ai
nd
*";;i"tini"l
proximal convoluted tubular cells, follicular epithelial
ceils of ttre thyroia gand and
macrophages-oflymph
nodes. ln the surviving animals, mild
wasobserved. and fenrcellswereeosinophiltand shrunken.
"y;;tlsmic'acuolizacon
rn *ereils&--nlurons,
eepecially
cells, had disappeared.
ttre
histoctremicar
P$nju
;;;beilar
secrions,
lrougtr
the l)rso-somal storage dlsease was ctrareiterized as an alphannannosidosis-
"*;"1
",rt;id*
The vacuoles
witlrin
urc
$r!$e.1etls strongfurcactedwith rectinsof {..meanawliaerrsifamk,Tritiamwrgads and
succinylated Tlititum wlgais. The patrern observed in *is in
n,slg;;n'i, ,i*it", to those
seen in other poisonings by swainsonine-containirg plants.
fNDEX TERIvIS: Sifu wrpini$lia, Malvaceae, lysosornd
storage disease, c_mannosidosis, goats, lectins.
rAceito para publica$io
em 2de abril de?[n2.
Trabslho r€alizado
bryoClirici
om srpote ftnaneirc
do
CNft (hoc.4764ti&t{}.
lrtefiel,hrindria, Uniwrdda&FldoElde tdeo Cm6so(uHlfrl,
C$iaht, M[ Autor para correcpond€mir- g*rai|: nMtena"or:r"tr
3Departanrurto_{g
Fatologia Clfnkra ttefednfuie, UFR6S, CL posral t5m4,
Ahgrq 8S 915,t0.{m0.
atlst{u_to
de pfiologie, Faculdade dc G€ncias\leterinfrias, Univcrsidade
_N*ional de La Plata, La phta, Arge{tina.
hto
_!1ry.le-fAsCraduag6o em fi€ncias veterin{rias, Irea Ae nalotogia,
cPGlftr-lJF*GS.
E-*agi:foia do_Deperhnento dG hfologia Clinica lrtteriniria; Bolsista
de
Funda$o de Ampro i ksquisa do Rio Gnmde do $ul
{F PERcs}.
Iniri@
tlaaiffca,
RESUMOT Este trabalho inclui os esffrdos
os
dftrims
e
patol6gi.
da doenga de armazenamento lisossomal indurida pJlo
Tn$umo espontineo de Srido carpinifria.n enfermidadi foi
obsenada em trts rcbqnh!!, quejunlou er"m composrsspor
!] canlnos, dos quais, 25 foram af,et"dos e 1t neorqsiados.
Nos trOs surtos, S. cmpinifolia *aa vegeta$o pr€donrinante
nos piquetes oorpados petos animais. Clinicamente,
a doen9a {racferizou€e por distfirbios nerrol6gicos que coruisti_
am de ataxia, hipermetria, poshlrus anormais, trrmores
muscslares.afetando principalmente as rqides da cabega pes
e
co.ga, dificuldade para ingesdo de alimentos e quedas-fr*
qiienEs. Estes sinais clinicos eram exacertedos pela
movi-