Original article End-of-life care: Portugal in the European project PRISMA Pedro Lopes Ferreira a,∗, Bárbara Antunes b,d, Ana Barros Pinto c e Bárbara Gomes d a Faculdade de Economia, Universidade de Coimbra, Centro de Estudos e Investigação em Saúde da Universidade de Coimbra, Coimbra, Portugal b Unidade de Psicologia da Dor, Centro de Estudos e Investigação em Saúde, Universidade de Coimbra, Coimbra, Portugal c Unidade de Oncologia, Hospital Santa Maria, EPE d Department of Palliative Care, Policy and Rehabilitation, Cicely Saunders Institute, King’s College, Londres, Reino Unido Abstract In Europe, there is a growing need for end-of-life care and for a definition of priorities for clinical practice and research in this health area. This article aims to present the activities of PRISMA (2008-2011), a project funded by the European Commission and led by King’s College London, involving an African partner and 12 European partners, including two in Portugal. It was intended to inform improvements in clinical practice and harmonising the research carried out in end-of-life care for cancer patients in Europe, by comparing approaches, experiences and priorities.