e-Poster
Correlations of Straylight,
Aberrometry, and Lens
Scattering in Cataract Patients
Bruno Valbon, MD
Frederico Guerra, MD; Daniela Jardim, MD;
Fernanda Fonyat, MD; Renato Ambrosio Jr., MD, PhD
Rio de Janeiro
Corneal
Tomography and
Biomechanics
Study Group
Setting : Instituto de Olhos Renato Ambrosio, Rio de Janeiro - Brasil
Dr. Ambrósio is a consultant for Oculus and is on the speaker bureau for Reichert, Allergan, Alcon and Moria.
e-Poster
Introduction
Cataract is a major cause of visual decline in older people.
The deterioration in visual function in these patients cannot be entirely
explained by spherical or cylindrical refractive errors.
Nuclear cataract can also decrease visual function by affecting contrast
sensitivity. Deterioration in contrast sensitivity can be explained
in terms of scatter and increased higher-order aberrations (HOAs)
Quality of vision loss because of eye media disturbances is limited not
only to visual acuity effects, but also to other effects such as caused by
straylight
Straylight increases with age in the perfectly healthy eye, but much more
so with disturbances to the optical media, such as cataract.
Rio de Janeiro
Corneal
Tomography and
Biomechanics
Study Group
The present study sought to take the next step by evaluating changes in
Setting
: Instituto
de Olhos
Renato
deeyes
Janeiro
the density
and optical
properties
of theAmbrosio,
crystalline Rio
lens in
with - Brasil
grades of nuclear cataract on LOCS III to establish the correlation
between the widespread subjective clinical classification and other objective
methods of quantifying nuclear lens opacification.
e-Poster
Purpose
To correlate straylight levels, lens
scattering, lens opacity and total
and intraocular aberrometry in
patients with cataract.
Rio de Janeiro
Corneal
Tomography and
Biomechanics
Study Group
Setting : Instituto de Olhos Renato Ambrosio, Rio de Janeiro - Brasil
SETTING : INSTITUTO DE OLHOS RENATO AMBROSIO, RIO DE JANEIRO, BRASIL
e-Poster
Rio de Janeiro
Corneal
Tomography and
Biomechanics
Study Group
Methods
Retrospective Study
Inclusion criteria: diagnosis of cataract
Exclusion criteria: corneal disease (other than up to mild guttata);
retinal or optic nerve disease and previous ocular surgery
Ocular straylight was evaluated using the C-Quant (Oculus)
Lens scattering was evaluated using the Scheimpflug Anterior
Segment Tomography (Pentacam , Oculus), using the new software
PNS
Total wavefront was measured by ray tracing (iTrace), intraocular
aberrations were calculated by the integration of the Placido
topography (Vista, Tracy Technologies)
Dilated slit lamp evaluation was performed and lens opacity was
classified according to LOCS scale
This is study analyzed was Kolmogorov-Smirnov for Normaliy
Correlation tests were performed.
Setting
: Instituto
de Olhos
Renato Ambrosio,
Rio de
Janeiro - Brasil
Either
variables
with Normal
Distribution:
Pearson
One of the variables with no Normal Distribution: Spearman
e-Poster
Rio de Janeiro
Corneal
Tomography and
Biomechanics
Study Group
Example 1: Early Cataract
PNS 1 ; HOA t 1,949
Setting : Instituto de Olhos Renato Ambrosio, Rio de Janeiro - Brasil
C-quant : log(s) 1,16 est 0,08 q 0,82
e-Poster
Example 2 – PNS 2 ; HOA t 0,508
Rio de Janeiro
Corneal
Tomography and
Biomechanics
Study Group
Setting : Instituto de Olhos Renato Ambrosio, Rio de Janeiro - Brasil
C-quant
: log(s)
2,70,64q
est 0,64
C-quant : log(s)
2,7est
-0,13q -0,13
e-Poster
Example 3 – PNS 3 ; HOA t 0,508
Rio de Janeiro
Corneal
Tomography and
Biomechanics
Study Group
Setting : Instituto de Olhos Renato Ambrosio, Rio de Janeiro - Brasil
C-quant : log(s) 1,27 est 0,05 q 2
e-Poster
Example 4 – PNS 4 ; HOA total 0,986
Rio de Janeiro
Corneal
Tomography and
Biomechanics
Study Group
Setting : Instituto de Olhos Renato Ambrosio, Rio de Janeiro - Brasil
C-quant : log(s) 1,85 est 0,06 q -0,13
e-Poster
Example 5 – PNS 5 ; HOA total 0,887
Rio de Janeiro
Corneal
Tomography and
Biomechanics
Study Group
Setting : Instituto de Olhos Renato Ambrosio, Rio de Janeiro - Brasil
C-quant : log(s) 1,74 est 0,06 q 0,63
RESULTS
e-Poster
30 eyes of 19 consecutive patients with nuclear opacity between
N01 and NO6 on the Lens Opacities Classification System III
Mean
Rio de Janeiro
Corneal
Tomography and
Biomechanics
Study Group
C-quant
Log(s)
PNS
LOCS
III
HOA t COMA
IO
IO
2,405
2,7
2,4
0,9118
0,5477+
+1,85
+1,14
+0,68
+ 0,35
0,31
Setting : Instituto de Olhos Renato Ambrosio, Rio de Janeiro - Brasil
RESULTS
e-Poster
rho
Rio de Janeiro
Corneal
Tomography and
Biomechanics
Study Group
rho
LOCS
III
C-quant
Tempo de
cirugia
FACO
HOA t
IO
PNS
0.7687
0.0203
-0.4167
-0.1248
rho
LOCSIII
HOAt IO
C-quant
-0.0592
0.0341
Setting : Instituto de Olhos Renato Ambrosio, Rio de Janeiro - Brasil
RESULTS
e-Poster
Graphics LOCS x PNS, Log(s) x PNS, Log(s) x LOCS
LOCS x PNS
Log (s) x PNS
6
6
y = 1.3942x - 0.646
R² = 0.6953
5
y = 0.0669x + 1.5419
R² = 0.245
5
4
4
3
3
2
2
1
1
0
0
0
1
2
3
4
5
0
10
20
30
40
Log (s) x LOCS
4.5
4
3.5
Rio de Janeiro
Corneal
Tomography and
Biomechanics
Study Group
3
y = 0.0027x + 2.3935
R² = 5E-05
2.5
Setting : Instituto
de Olhos Renato Ambrosio, Rio de Janeiro - Brasil
2
1.5
1
0.5
0
0
1
2
3
4
5
6
7
e-Poster
CONCLUSION
New mehtods for diagnosing cataract have been introduced
C-Quant measurement of the straylight (glare disability) is an
important new functional parameter
The Scheimpflug Tomography by the Pentacam calculates the
PNS scale which has a very high correlation with the slit lamp
biomicroscopy exam.
Optical analysis with aberrometry also has weak correlation
Rio de Janeiro
Corneal
Tomography and
Biomechanics
Study Group
Setting : Instituto de Olhos Renato Ambrosio, Rio de Janeiro - Brasil