CATARATA, TRAUMATOLOGIA, RETINA CIRÚRGICA
08:50 | 11:00 - Sala Vega
Mesa: Adriano Aguilar, Angelina Meireles, Filipe Henriques
VD38- 10:50/11:00
RETIDYNE: THE GREEN EFFECT
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José Costa , João Pedro Marques , Sérgio Brito , Diogo Sousa Martins , Luís Ferreira , João Figueira
(1-Centro de Responsabilidade Integrado em Oftalmologia do Centro Hospitalar e Universitário de Coimbra (CRIO2
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CHUC), Kemin Industries, Inc., Centro de Responsabilidade Integrado em Oftalmologia do Centro Hospitalar e
Universitário de Coimbra (CRIO-CHUC), Associação para a Investigação Biomédica e Inovação em Luz e Imagem
(AIBILI), 4-Centro de Responsabilidade Integrado em Oftalmologia do Centro Hospitalar e Universitário de Coimbra
(CRIO-CHUC); Associação para a Investigação Biomédica e Inovação em Luz e Imagem (AIBILI); Faculdade de
Medicina)
Introduction
We aim to present a case of internal limiting membrane (ILM) peeling after staining with a novel natural dye solution
composed of lutein in association with brilliant blue – RetidyneTM (Kemin, USA).
Materials and methods
Combined cataract surgery and pars plana chromovitrectomy was performed. Phacoemulsification was
accomplished using an ultrasonic OZIL® tip (INFINITI®, Alcon, USA). A foldable acrylic intraocular lens was
subsequently inserted. Pars plana vitrectomy with a 23-gauge incision was performed using the 5000 cuts per
minute platform of the Constellation® system (Alcon, USA). RetidyneTM (Kemin, USA) was used to stain the ILM.
The green dye deposited on the posterior pole because of its higher density than balanced saline solution; vigorous
dye flushing into the vitreous cavity was unnecessary. Partial peeling of the ILM was achieved using ILM 23G
forceps (Grieshaber, USA). The inverted ILM flap technique was used to improve rates of anatomical closure of the
macular hole.
Results
A 67-year-old female patient complaining of progressive reduction of visual acuity in her left eye presented with a
nuclear cataract and a large full thickness macular hole (narrowest width measured with spectral-domain optical
coherence tomography was 712μm). Both phacoemulsification and chromovitrectomy were uneventful. The novel
lutein-based dye successfully stained the ILM, thus facilitating its partial removal and completion of the inverted ILM
flap technique. No safety concerns possibly related to the dye and/or the surgical procedures were observed. Both
anatomical and functional improvements were accomplished.
Conclusions
The ideal vital dye should be safe for intraocular use, for reliable and selective staining of the intraocular
membranes, and for rapid elimination from the eye. RetidyneTM showed efficacy in the intraoperative identification of
the ILM, thus confirming its usefulness for chromovitrectomy. No dye-related adverse events were reported.