Applied Research in Toxicolgy the official journal of the Brazilian Society of Toxicology, publishes peer-reviewed original scientific research in all fields of toxicology, including but not limited to nanotoxicology, genomics and proteomics, teratogenesis, carcinogenesis, mutagenesis, reproductive and endocrine toxicology, toxicopathology, target organ toxicity, neurobehavioral toxicology, mechanistic studies, biochemical and molecular toxicology, novel biomarkers, risk assessment and environmental health studies. Manuscripts on clinical toxicology and its aspects, toxicodynamics and toxicokinetics are also accepted. In addition to original research articles, concise and current review and mini-review articles are also welcome, as are case report papers. Board of Editors EDITOR-IN-CHIEF Daniel J. Dorta Brazilian Society of Toxicology University of São Paulo Ribeirão Preto, Brazil EDITORS Silvia B. M. Barros Brazilian Society of Toxicology São Paulo, Brazil Eduardo M. De Capitani Brazilian Association of Information Centers and Toxicological Assistance and Clinical Toxicologists Campinas, Brazil Gisela A. Umbuzeiro Brazilian Society of Environmental Mutagenesis, Carcinogenesis and Teratogenesis Campinas, Brazil ASSOCIATE-EDITORS Bruno Megarbane University of Paris Paris, France Carlos M. Palmeira University of Coimbra Coimbra, Portugal João Lauro Viana de Camargo State University Paulista São Paulo, Brazil Danielle Palma de Oliveira University of São Paulo Ribeirão Preto, Brazil Mauricio Yonamine University of São Paulo São Paulo, Brazil EDITORIAL BOARD Bruno Spinosa de Martinis - University of São Paulo - Ribeirão Preto, Brazil José Luiz da Costa - Criminalistics Institute of the State of São Paulo - São Paulo, Brazil Fábio Bucaretchi - State University of Campinas - Campinas, Brazil Fernando Barbosa Junior - University of São Paulo - São Paulo, Brazil Paulo Jorge Oliveira - University of Coimbra - Coimbra, Portugal