FCT PhD Programme
Medicines and Pharmaceutical Innovation (i3DU)
Course
BioPharmaceuticals and Advanced Therapies
28-2 September/October 2015
Faculdade de Farmácia, Universidade de Lisboa - Auditorium
Lisbon, Portugal
The FCT PhD Programme in Medicines and Pharmaceutical Innovation (i3DU) trains
students in target discovery, drug design, pre-clinical development, and drug safety,
bridging the translational gap from discoveries on disease targets and mechanisms
into novel diagnostic and therapeutic agents.
The i3DU Programme offers a training course that will be held at the Research
Institute for Medicines (iMed.ULisboa), Faculdade de Farmácia, Universidade de
Lisboa, in Lisbon, 28-2 September/October 2015.
Course outline
The course on Biopharmaceuticals and Advanced Therapies covers critical aspects of
biopharmaceuticals and advanced therapies from discovery methods to development
of therapies, with emphasis on success cases of antibodies, gene therapy and cell
therapy.
The aim of this training course is to delivery not only state-of-the-art information
but also to give training on the different aspects of biopharmaceuticals. As the
functions of biopharmaceuticals are fully explored and utilised, they will become
increasingly relevant to the drug development community.
The training program welcomes the participation of external academic and scientific
community members. Registration is free but mandatory.
Organizing committee
João Gonçalves, iMed.ULisboa/ FFULisboa (Coordinator)
Sofia Corte-Real, TechnoPhage
Mariana Santa-Marta, iMed.ULisboa/ FFULisboa
Paula Brito
1
Discovery of Biopharmaceutical proteins
September 28, 2015
10h00
Different classes of biopharmaceuticals
João Gonçalves
iMed.ULisboa
Faculdade de Farmácia, Universidade de Lisboa
Lisbon, Portugal
11h00
In vivo models for biopharmaceutical discovery
António Duarte
Faculdade de Medicina Veterinária, Universidade de Lisboa
Lisbon, Portugal
Lunch Break
14h00
Sea as a source of biopharmaceutical leads
Helena Vieira
Faculdade de Ciências, Universidade de Lisboa
Lisbon, Portugal
15h00
Why use Zebrafish as a discovery model for biopharmaceuticals?
Sara Sousa
TechnoPhage
Lisbon, Portugal
16h30
Regulatory overview of biologic advanced therapies
Margarida Menezes
Infarmed
Lisbon, Portugal
2
Biopharmaceuticals: the success case-study of antibody therapy
September 29, 2015
10h00
The discover methodology of therapeutic antibodies
Diana Ramos
FairJourney Biologics
Oporto, Portugal
11h00
Alternative antibody scaffolds for therapy
Soraia Oliveira
TechnoPhage
Lisbon, Portugal
Lunch Break
14h00
Chemical Biology and Antibody Drug Conjugates
Pedro Góis
iMed.ULisboa
Faculdade de Farmácia, Universidade de Lisboa
Lisbon, Portugal
15h00
Therapeutic Antibodies for autoimmunity/Inflammation
João Eurico
Instituto de Medicina Molecular
Faculdade de Medicina, Universidade de Lisboa
Lisbon, Portugal
16h30
Therapeutic Antibodies for cancer
João Gonçalves
iMed.ULisboa
Faculdade de Farmácia, Universidade de Lisboa
Lisbon, Portugal
3
Methodology for Development of Biopharmaceutical medicines
September 30, 2015
10h00
Production methodologies for biopharmaceuticals and regulatory
environment
Maria Henriques Ribeiro
iMed.ULisboa
Faculdade de Farmácia, Universidade de Lisboa
Lisbon, Portugal
11h00
Formulation of biopharmaceuticals
Helena Florindo
iMed.ULisboa
Faculdade de Farmácia, Universidade de Lisboa
Lisbon, Portugal
Lunch Break
14h00
Pre-clinical trials for biopharmaceuticals
Sofia Corte-Real
TechnoPhage
Lisbon, Portugal
15h00
How to setup and analyze data from clinical trials?
António Mata
Faculdade de Medicina Dentária, Universidade de Lisboa
Lisbon, Portugal
16h30
How biopharmaceutical quality influences safety and efficacy of
biopharmaceuticals
John Milne
National Institute for Biologic Research and Training
Ireland
4
Advanced Biologic Therapies
October 1, 2015
10h00
Pharmacokinetics of therapeutic proteins
Nuno Elvas
iMed.ULisboa
Faculdade de Farmácia, Universidade de Lisboa
Lisbon, Portugal
11h00
Immunogenicity of therapeutic proteins
Joana Costa
Instituto de Biologia Molecular e Celular
Faculdade de Medicina da Universidade do Porto
Oporto, Portugal
Lunch Break
14h00
Gene therapy with viral and non-viral vectors
Gabriela Silva
Centro de Estudos de Doenças Crónicas
Faculdade de Ciências Médicas da Universidade Nova de Lisboa
Lisbon, Portugal
15h00
Can Phages be biopharmaceuticals?
Madalena Pimentel
iMed.ULisboa
Faculdade de Farmácia, Universidade de Lisboa
Lisbon, Portugal
16h30
From Bench to patient with cell therapy
Afonso Almeida
Instituto de Medicina Molecular, Universidade de Lisboa
Lisbon, Portugal
5
The industry view of Biopharmaceuticals
October 2, 2015
10h00
Worldwide Development of Biosimilars
António Silva
Sandoz Biopharmaceuticals
Austria
11h00
Differentiation of Human Mesenchymal stromal/stem cells and
applications in therapy
Pedro Cruz
ECBio
Portugal
Lunch Break
14h00
How to bring value in the competitive market of
biopharmaceutical production
Teresa Alves
GenIbet
Portugal
15h00
Market access of biopharmaceuticals: The end of the line?
Carla Paixão
Roche Farmacêutica
Portugal
16h30
Discovery and Development at Centers for Therapeutic
Innovation (CTI)
Isaac Rondon
Pfizer Inc.
USA
6