João Silva Soares
Curriculum Vitae
Stony Brook University
Department of Biomedical Engineering
Biofluids Laboratory
address: Health Sciences Center, T-18, Rm. 030
Stony Brook University
Stony Brook, NY 11794-8181
phone: (+1) 631 444 2799
fax: (+1) 631 444 6646
e-mail: [email protected]
url: http://www.math.ist.utl.pt/~jsoares/
I.
Education
Ph.D., Mechanical Engineering, Texas A&M University, College Station, Texas, USA
September 2003 – May 2008
Dissertation: Constitutive Modeling for Biodegradable Polymers for
Application in Endovascular Stents
Advisors: Kumbakonam R. Rajagopal, James E. Moore, Jr.
Licenciatura, Aerospace Engineering, Instituto Superior Técnico/UTL, Lisbon, Portugal
September 1996 – July 2002
Thesis: Development of Computational Fluid Dynamics Techniques for the
Analysis of the External Flow around Supersonic Rockets
Advisor: João M. Sousa
II. Professional Activity
1)
Senior Post Doctoral Associate
October 2011 – present
PI: Danny Bluestein
Stony Brook University
Department of Biomedical Engineering
2)
Visiting Post Doctoral Fellow
April 2011 – May 2011
Fundação para a Ciência e Tecnologia
Politenico di Milano, Italia
MOX – Department of Mathematics
3)
Post Doctoral Fellow
February 2010 – September 2011
Fundação para a Ciência e Tecnologia
Instituto Superior Técnico, Lisbon, Portugal
CEMAT – Department of Mathematics
Project: Mathematical modeling of tumor growth supervised by Adélia Sequeira
4)
Post Doctoral Fellow
Politecnico di Milano, Italia
February 2009 – January 2010
MOX – Department of Mathematics
Project: Models and methods for degradable materials
5)
Auxiliary Researcher
October 2008 – January 2010
Supervisor: Adélia Sequeira
6)
Doctoral Fellow
Research Assistant
September 2004 – September 2008
7)
Teaching Assistant
Texas A&M University, College Station, TX, USA
September 2003 – August 2004
Department of Mechanical Engineering
Courses handled: Statics & Particle Dynamics supervised by R.M. Bowen and A.B. Palazzolo
Engineering Technology supervised by M.T. Schobeiri
Instituto Superior Técnico, Lisbon, Portugal
CEMAT – Department of Mathematics
Fundação para a Ciência e Tecnologia
Texas A&M University, College Station, TX, USA
Department of Mechanical Engineering
Department of Biomedical Engineering
Supervisors: Kumbakonam R. Rajagopal, James E. Moore, Jr.
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João Silva Soares
8)
Curriculum Vitae
Teaching & Research Assistant
Instituto Superior Técnico, Lisbon, Portugal
September 2000 – February 2002
Department of Mechanical Engineering
Courses handled: Computational Mechanics supervised by Luís Faria
III. Publications
Peer Reviewed Journal Publications:
1) J.S. Soares, S. Pasta, D.A. Vorp, J.E. Moore, Jr., Modeling in Cardiovascular Mechanics, International
Journal of Engineering Science (2010) 48:1563-1575.
2) J.S. Soares, J.E. Moore, Jr., K.R. Rajagopal, Modeling of Deformation-Accelerated Breakdown of
Polylactic Acid Biodegradable Stents, ASME Journal of Medical Devices (2010) 4.
3) J.E. Moore, Jr., J.S. Soares, K.R. Rajagopal, Biodegradable stents: biomechanical modeling challenges and
opportunities, Cardiovascular Engineering Technology (2010) 1:52-65.
4) J.S. Soares, P. Zunino, A mathematical model for water uptake, degradation, erosion, and drug release from
polydisperse polymeric networks, Biomaterials (2010) 31:3032-3042.
5) J.S. Soares, K.R. Rajagopal, J.E. Moore, Jr., Deformation induced hydrolysis of a degradable polymeric
cylindrical annulus, Biomechanics and Modeling in Mechanobiology (2010) 9:177-186.
6) J.S. Soares, Bioabsorbable polymeric drug-eluting endovascular stents: a clinical review, Minerva
Biotecnologica (2009) 21:217-230.
7) J.S. Soares, Diffusion of a fluid through a spherical elastic solid undergoing large deformations,
International Journal of Engineering Science (2009) 47:50-63.
8) J.S. Soares, J.E. Moore, Jr., K.R Rajagopal, Constitutive Framework for biodegradable polymers with
applications to biodegradable stents, ASAIO Journal (2008) 54:(3):295-301.
Other Publications (book sections, extended conference proceedings, technical reports, etc):
1) P. Zunino, S. Vesentini, A. Porpora, J.S. Soares, A. Gautieri, A. Redaelli, Multiscale computational analysis
of degradable polymers, MOX Technical Report 10-2011, MOX – Modellistica e Calcolo Scientifico,
Dipartimento di Matematica, Politecnico di Milano, Milano, Italia, 2011.
2) P. Zunino, A. Porpora, S. Vesentini, A. Gautieri, J.S. Soares, A. Redaelli, Multiscale computational analysis
of degradable polymers, in: A. Quarteroni (Ed.) Proceedings of the MPF2010 – IV International Symposium
on Modelling of Physiological Flows, Springer, Milano, Italia.
3) J.S. Soares, P. Zunino, A mathematical model for water uptake, degradation, erosion, and drug release from
polydisperse polymeric networks, MOX Technical Report 18-2009, MOX – Modellistica e Calcolo
Scientifico, Dipartimento di Matematica, Politecnico di Milano, Milano, Italia, 2009.
4) J.S. Soares, Constitutive modeling of biodegradable polymers for tissue engineering scaffolds, in: P. J.
Bártolo et al. (Eds), Proceedings of ICTE2009 - International Conference on Tissue Engineering, IST Press,
Lisboa, Portugal, 2009, pp. 163-170.
5) J.S. Soares, Constitutive modeling of biodegradable polymers for application in endovascular stents, PhD
dissertation, Texas A&M University, College Station, Texas, USA, 2008.
6) J.S. Soares, J.E. Moore, Jr., K.R. Rajagopal, Theoretical modeling of cyclically loaded biodegradable
cylinders, in: F. Mollica, L. Preziosi, K.R. Rajagopal, (Eds), Modeling biological materials, Birkhauser,
Boston, 2007, pp. 125-177.
7) J.S. Soares, J.E. Moore, Jr., K.R. Rajagopal, Theoretical modeling of cyclically loaded biodegradable
cylinders, in: C.A. Mota Soares et al. (Eds), ECCM2006, Computational Mechanics: Solids, Structures and
Coupled Problems in Engineering, Springer, Lisboa, Portugal, 2006.
Abstracts in Conference Proceedings:
1) J.S. Soares, J. Sheriff, D. Bluestein, A mathematical model for shear-induced platelet activation in response
to time dependent shear stress histories, Proceedings of the ASME 2012 Summer Bioengineering
Conference, Fajardo, Porto Rico, 2012 (submitted).
2) J. Sheriff, M. Xenos, J.S. Soares, J. Jesty, D. Bluestein, Evaluation of platelet activation models with
dynamic shear stress in vitro experiments, Proceedings of the ASME 2012 Summer Bioengineering
Conference, Fajardo, Porto Rico, 2012 (submitted).
3) J.S. Soares, Modeling polymer degradation and erosion for biodegradable biomedical implant design,
Proceedings of the 10th International Conference on Computational and Mathematical Methods in Science
and Engineering, CMMSE2011, Benidorm, Spain, 2011.
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João Silva Soares
Curriculum Vitae
4) J.S. Soares, Modeling polymer degradation and erosion for biodegradable biomedical implant design,
Proceedings of Mathematical Fluid Mechanics and Biomedical Applications (dedicated to Prof. Adélia
Sequeira on the occasion of her 60th birthday), Universidade dos Açores, Portugal, 1-3 Jun 2011.
5) J.S. Soares, P. Zunino, Modelação Multi-Escala do Processo de Degradação e Erosão de Polímeros
Biodegradáveis, Livro de Actas do 4º Congresso de Nacional de Biomecânica, Coimbra, Portugal, 2011.
6) J.S. Soares, P. Zunino, A multiscale mixture model for polymer degradation and erosion, Proceedings of the
ASME 2010 Summer Bioengineering Conference, Naples, FL, 2010.
7) J.E. Moore, Jr., J.S. Soares, K.R. Rajagopal, Modeling of biodegradable stents subjected to physiologic
loading, Proceedings of the FDA & NHLBI 3rd Annual Workshop on Computer Methods and
Cardiovascular Devices: The integration of nonclinical and computer methods, Rockville, MD, 2010.
8) J.S. Soares, S. Minisini, P. Zunino, Multiscale analysis of degradable polymers: from nanoscale to
macroscale modeling , Proceedings of the 4th International Symposium Mathematical and Numerical
Modelling of Physiological Flows, Chia Lagua, Italy, 2010.
9) J.S. Soares, P. Zunino, A multiscale mixture approach to describe polymer degradation and erosion,
Proceedings of the Endovascular Biomechanics Symposium Research, Marseille, France, 2010.
10) J.S. Soares, P. Zunino, A mathematical model for water uptake, degradation and erosion of polydisperse
biodegradable polymers, Proceedings of the BMES Annual Fall Meeting, Pittsburgh, PA, 2009.
11) J.S. Soares, K.R. Rajagopal, J.E. Moore, Jr., A constitutive model for deformation induced degradation of
polymers: inflation and extension of a degradable cylindrical annulus, Proceedings of the 7th EUROMECH
Solid Mechanics Conference, Lisboa, Portugal, 2009.
12) J.S. Soares, J.E. Moore, Jr., K.R. Rajagopal, Constitutive model of deformation induced degradation of
polymers for application in biodegradable stent design, Proceedings of the 3rd International Conference on
Integrity, Reliability and Failure, Porto, Portugal, 2009.
13) J.S. Soares, Constitutive modeling of biodegradable polymers for tissue engineering scaffolds, Proceedings
of the 1st International Conference on Tissue Engineering, Leiria, Portugal, 2009.
14) J.S. Soares, J.E. Moore, Jr., K.R. Rajagopal, Mechanics of deformation-induced degradation of poly(Llactic acid) endovascular stents, Proceedings of the ASME Summer Bioengineering Conference, Lake
Tahoe, CA, 2009.
15) J. S. Soares, M.A. Grunlan, J.E. Moore, Jr., K.R. Rajagopal, Constitutive modeling for biodegradable
nonlinear polymers with application in biodegradable endovascular stents, Proceedings of the HSEMB,
Houston, TX, 2008.
16) J.E. Moore, Jr., M. Moreno, J.S. Soares, L.H. Timmins, C. Meyer, Stented artery biomechanics and design
rationale for biodegradation, Proceedings of the Society of Engineering Science Meeting, College Station,
TX, 2007.
17) J.S. Soares, Constitutive modeling of biodegradable nonlinear polymers for application in the medical field,
Proceedings of the Society of Engineering Science Meeting, College Station, TX, 2007.
18) J.S. Soares, J.E. Moore, Jr., K.R. Rajagopal, Constitutive model of biodegradable nonlinear polymeric
materials for applications in the biomedical field, Proceedings of the ASME Summer Bioengineering
Conference, Keystone, CO, 2007.
19) J.S. Soares, J.E. Moore, Jr., K.R. Rajagopal, Biomechanical Modeling of Biodegradation, Proceedings of
the BMES Annual Fall Meeting, Chicago, IL, 2006.
20) J.S. Soares, J.E. Moore, Jr., K.R. Rajagopal, Theoretical modeling of cyclically loaded biodegradable
cylinders, Proceedings of the ASME Summer Bioengineering Conference, Amelia Island, FL, 2006.
21) J.S. Soares, J.E. Moore, Jr., K.R. Rajagopal, Theoretical modeling of cyclically loaded biodegradable
cylinders, Proceedings of the III European Conference on Computational Mechanics, Springer, Lisboa,
Portugal, 2006.
22) J.S. Soares, J.E. Moore, Jr., K.R. Rajagopal, Modeling Strategies for Biodegradable Stents, Proceedings of
the Endovascular Biomechanics Research Symposium, Marseille, France, 2006.
IV. Conference Presentations
1) 10th International Conference on Computational and Mathematical Methods in Science and Engineering,
CMMSE2011, Benidorm, Spain, 26-30 Jun 2011.
2) Invited Plenary Lecture, Mathematical Fluid Mechanics and Biomedical Applications (dedicated to Prof.
Adélia Sequeira on the occasion of her 60th birthday), Universidade dos Açores, Portugal, 1-3 Jun 2011.
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João Silva Soares
Curriculum Vitae
3) Invited Lecture, Perambulation of Continuum Mechanics, meeting in celebration of the 60th birthday of K.R.
Rajagopal, Texas A&M University, College Station, TX, 11-13 Nov 2010.
4) ASME 2010 Summer Bioengineering Conference (ASME SBC2010), Naples Grand Beach Resort, Naples,
FL, 16-19 Jun 2010
5) Endovascular Biomechanics Research Symposium (EBR2010), Hotel Pullman Palm Beach, Marseille,
France, 6-7 May 2010
6) 7th EUROMECH Solid Mechanics Conference (ESMC2009), Instituto Superior Técnico, Lisboa, Portugal,
7-11 Sep, 2009
7) 3rd International Conference on Integrity, Reliability and Failure (IRF2009), Faculdade de Engenharia da
Universidade do Porto, Porto, Portugal, 20-24 Jul 2009
8) 1st International Conference on Tissue Engineering (ICTE2009), Instituto Politécnico de Leiria, Leiria,
Portugal, 9-11 Jul 2009.
9) 25th Annual Houston Conference on Biomedical Engineering Research (HSEMB2008), University of
Houston, Houston, TX, 7-8 Feb 2008.
10) 44th Annual Technical Meeting Society of Engineering Science (SES2007), Texas A&M University,
College Station, TX, 21-24 Oct 2007.
11) III European Conference on Computational Mechanics (ECCM2006), Laboratório Nacional de Engenharia
Civil, Lisboa, Portugal, 5-8 Jun 2006.
Given by co-authors:
1) FDA & NHLBI 3rd Annual Workshop on Computer Methods and Cardiovascular Devices: The integration
of nonclinical and computer methods, Rockville, MD, 10-11 Jun 2010.
2) 4th International Symposium Mathematical and Numerical Modelling of Physiological Flows (MPF2010),
Chia Lagua, Italy, 2-5 Jun 2010.
3) ASME 2009 Summer Bioengineering Conference (SBC2009), Resort at Squaw Creek, Lake Tahoe, CA, 1720 Jun 2009.
4) 44th Annual Technical Meeting Society of Engineering Science (SES2007), Texas A&M University,
College Station, TX, 21-24 Oct 2007.
5) ASME 2006 Summer Bioengineering Conference (SBC2006), Amelia Island Plantation, Amelia Island, FL,
21-25 Jun 2006.
6) Endovascular Biomechanics Research Symposium (EBR2006), Hotel Pullman Palm Beach, Marseille,
France, 1-2 Jun 2006.
Poster presentations:
1) 4º Congresso Nacional de Biomecânica, Coimbra, Portugal, 4-5 Feb 2011.
2) Endovascular Biomechanics Research Symposium (EBR2010), Hotel Pullman Palm Beach, Marseille,
France, 6-7 May 2010
3) BMES Annual Fall Scientific Meeting (BMES2009), Pittsburgh, PA, 7-10 Oct 2009.
4) 5th BME Annual Poster Day, Zachry Engineering Center, Texas A&M University, College Station, TX, 22
Aug 2007.
5) ASME 2007 Summer Bioengineering Conference (SBC2007), Keystone Conference Center, Keystone, CO,
20-24 Jun 2007.
6) BMES Annual Fall Scientific Meeting (BMES2006), Northwestern University, Chicago, IL, 11-14 Oct
2006.
7) 4th BME Annual Poster Day, Zachry Engineering Center, Texas A&M University, College Station, TX, 21
Aug 2006.
8) 3rd BME Annual Poster Day, Zachry Engineering Center, Texas A&M University College Station, TX, 24
Aug 2005.
V. Seminars and Invited Lectures
1) Applied Mathematics and Numerical Analysis Seminar, Instituto Superior Tecnico, Portugal, Jul 2011.
2) Invited Plenary Lecture, Mathematical Fluid Mechanics and Biomedical Applications, Universidade dos
Açores, Portugal, Jun 2011.
3) MOX – Modelling and Scientific Computing, Dipartimento di Matematica, Politecnico di Milano, Italia,
May 2011.
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João Silva Soares
Curriculum Vitae
4) Invited Lecture, Perambulation of Continuum Mechanics, meeting in celebration of the 60th birthday of K.R.
Rajagopal, Texas A&M University, College Station, TX, Nov 2010.
5) Institute for Computational Engineering and Sciences, University of Texas, Austin, USA, Nov 2010
6) Department of Mechanical Engineering, Instituto Superior Tecnico, Portugal, Nov 2010.
7) MOX – Modelling and Scientific Computing, Dipartimento di Matematica, Politecnico di Milano, Italia,
Dec 2009.
8) Applied Mathematics and Numerical Analysis Seminar, Instituto Superior Tecnico, Portugal, Nov 2009.
9) Dipartimento di Matematica, Politecnico di Torino, Italia, Nov 2009
10) MOX – Modelling and Scientific Computing, Dipartimento di Matematica, Politecnico di Milano, Italia,
Feb 2009.
11) Dipartimento di Matematica, Politecnico di Torino, Italia, Nov 2008.
12) Applied Mathematics and Numerical Analysis Seminar, Instituto Superior Tecnico, Portugal, Oct 2008.
VI. Other Appearances
1) Abaqus Technology Brief, TB-10-BSTENT-1, Modeling Biodegradable Polymeric Stents using
Abaqus/Standard, Dassault Systèmes, Providence, RI, 2010 (available online at http://simulia.
custhelp.com/cgi-bin/abaqus.cfg/php/enduser/doc_serve.php?2=emailreq2_techbriefs_simweb)
VII. Honors and Awards
1) Young Investigator Biomechanical Award, Endovascular Biomechanics Research Symposium (EBR2010),
Hotel Pullman Palm Beach, Marseille, France, 6-7 May 2010
VIII. Research Projects and Support
1) “Cardiovascular Imaging, Modelling and Simulation – SIMCARD”, Project UTAustin/CA/0047/2008, PI:
Adélia Sequeira (IST) and Tom Hughes (UTAustin). Soares was involved in the collaborative project
between CEMAT/IST and ICES/UTAustin since February 2010.
2) Post-doctoral fellowship SFRH/BPD/63119/2009, “Mathematical Modeling of Tumor Growth”, Fundação
para a Ciência e Tecnologia, Portugal. Soares applied for funding individually and participates as postdoctoral fellow since 2010 at the Department of Mathematics of Instituto Superior Técnico, Lisboa,
Portugal.
3) “Models and methods for degradable materials” by the Italian Institute of Technology. Soares participated
as post doctoral fellow in 2009 at the Deparment of Mathematics of Politecnico di Milano, Italy.
4) “Stented Artery Wall Stresses and Restenosis”. PI: James E. Moore Jr. NIH (R01). Goal: Quantify the
stresses in a stented artery wall in different stent designs and evaluate the inflammatory responses of each in
an animal model. Soares participation was graduate research assistant at the Department of Biomedical
Engineering at Texas A&M University for 2004-2008.
5) Doctoral fellowship SFRH/BD/17060/2004, “Biodegradable Stents”, Fundação para a Ciência e Tecnologia,
Portugal. Soares applied for funding individually and participated as doctoral fellow at the Deparment of
Mechanical Engineering at Texas A&M University for 2004-2008.
IX. Student Research Supervising
Projects Supervised:
1) Nelson Ribeiro, Department of Mathematics, Instituto Superior Tecnico. Soares was co-supervisor with A.
Sequeira during Spring 2010 on graduate course project “FEM analysis of stent deployment”.
2) Andy Peters, Department of Biomedical Engineering, Texas A&M University. Soares was co-supervisor
with J.E. Moore Jr. during Spring 2007 on senior project “Finite element analysis of wave propagation and
the effects of treatment of bronchopulmonary dysplasia with stents”.
3) Dirk Rosenstock, Department of Mechanical Engineering, Ruhr University Bochum. Soares was cosupervisor with K.R. Rajagopal during Fall 2006 at Texas A&M University on senior project “Design of a
degradation chamber for degradation of poly-L-lactic acid fibers under constant tension”.
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João Silva Soares
Curriculum Vitae
X. Peer-reviewing activity
Grant reviewer for:
1) Research Grants Council Hong Kong, China
2) FONDECYT, Fondo Nacional de Desarrollo Cientifico y Tecnologico, Chile
Reviewer for:
1) Molecular Pharmaceutics (American Chemical Society)
2) Annals of Biomedical Engineering (Springer)
3) Journal of Molecular Modeling (Springer)
4) Theoretical Biology and Medical Modelling (Biomed Central)
5) Medical & Biological Engineering & Computing (Springer)
6) Biomechanics and Modeling in Mechanobiology (Springer)
7) American Journal of Physiology – Heart and Circulatory Physiology (American Physiological Society)
8) Journal of Biomaterials (Elsevier)
9) International Journal of Solids and Structures (Elsevier)
10) Medical Engineering & Physics (Elsevier)
11) Journal of Medical Devices (ASME)
12) Biomedical Engineering Online (BioMed Central)
13) Journal of Biomechanical Engineering (ASME)
14) Journal of Fluid Mechanics (Cambridge Journals)
XI. Memberships in Professional Societies
1) Sociedade Portuguesa de Biomecânica, Delegado (since 2010)
2) BMES, Biomedical Engineering Society, Early Career Member (since 2009)
3) ASME-BED, American Society of Mechanical Engineers – Bioengineering Division, Solids Technical
Committee member (since 2008)
XII. Organization of Conferences and Workshops
1) ASME 2012 Summer Bioengineering Conference, June 2012, Fajardo, Porto Rico (Solids Technical
Committee member, abstract reviewer, conference chair: Dr. Dawn Elliott).
2) ASME 2011 Summer Bioengineering Conference, June 2011, Farmington, PA (Solids Technical Committee
member, abstract reviewer, conference chair: Dr. David A. Vorp)
3) Conference on Mathematical Fluid Mechanics and Biomedical Applications, June 2011, Universidade dos
Açores, Ponta Delgada, Portugal (organizing committee, conference chair: Dr. Hugo Beirão da Veiga).
4) ASME 2010 Summer Bioengineering Conference, June 2010, Naples, FL (Solids Technical Committee
member, abstract reviewer, student paper competition jury member, conference chair: Dr. Rita M.
Patterson)
5) ASME 2009 Summer Bioengineering Conference, June 2009, Lake Tahoe, CA (Solids Technical
Committee member, abstract reviewer, conference chair: Dr. Dawn Elliott).
6) Lectures on Modelling Cancer Growth and Treatments, December 2008, Estoril, Portugal (organizing
committee member, conference chair: Dr. Adélia Sequeira).
[email protected]
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