12TH MEDINTERNA INTERNATIONAL MEETING Centro Hospitalar S. João Cutting Edge Autoimmunity _______________________________________ 27th-28th February and 01st March 2014 Fundação Dr. António Cupertino de Miranda Porto, Portugal 27TH FEBRUARY THURSDAY VASCULITIS MORNING 08H15 – SECRETARIAT DESK OPENING 09H00 – LECTURE Chair – Isabel Abreu| Lisbon, Portugal Conflicting laboratory results in Autoimmunity, why? João Faro Viana| Lisbon, Portugal 09H30 – LECTURE Chairman – António Morais| Porto, Portugal Pulmonary involvement in Sarcoidosis Athol Wells| London, Uk 10H00 – OPENING CEREMONY Chairman – António Lobo Ferreira| Porto, Portugal 10H45 – LECTURE Chairman – Paulo Bettencourt| Porto, Portugal Vitamin D – The new antibiotic and immunomodulator agent in autoimmune diseases Yehuda Shoenfeld| Tel Aviv, Israel 11H15 – COFFEE-BREAK 11H45 – FACE-TO-FACE Chairs – Maria José Sousa| Lisbon, Portugal and Teresa Faria| Funchal, Portugal A Salsa of Sjogren’s Syndrome Jan Damoiseaux| Maastricht, The Netherlands Jan Willem Cohen Tervaert| Maastricht, The Netherlands 12H30 – LECTURE Chairman – Jorge Martins| Funchal, Portugal Biologics in Sjogren’s Syndrome Cees Kallenberg| Groningen, The Netherlands 13H00 – LUNCH ARTHRITIS AFTERNOON 14H30 – ROUND TABLE Chairman – João Eurico Fonseca| Lisbon, Portugal Nanoinflammation: bridges between Bone and Vessel Bruno Vidal| Lisbon, Portugal Diana Fernandes| Lisbon, Portugal 15H30 – LECTURE Chair – Mariana Guimarães| Porto, Portugal Management of Pregnancy in patients with Rheumatic diseases Monika Ostensen| Kristiansand, Norway 16H00 – LECTURE SPONSORED BY GLAXOSMITHKLINE Chairman – Joaquim Andrade| Porto, Portugal Thrombocitopenic Idiopathic Purpura José Luís Ducla-Soares| Lisbon, Portugal 16H30 – COFFEE BREAK 17H00 – LECTURE Chair – Francisca Fontes| Lisbon, Portugal ASIA syndrome – 2014 Carlo Perricone| Rome, Italy 17H30 – LECTURE SPONSORED BY ROCHE Chairman – Jorge Fortuna| Coimbra, Portugal Each patient is one patient: a renewed look on RoACTEMRA Pedro Vita| Porto, Portugal 18H00 – CASE REPORT 1 Chair – Mónica Bogas| Ponte de Lima, Portugal Dorsalgy in a diabetic patient Case Report – Ana Eduarda Raposo| Ponte de Lima, Portugal Discussion – Miguel Bernardes| Porto, Portugal, Maria José Serra | Lisbon, Portugal and Borges Alexandrino| Coimbra, Portugal 18H45 – CLOSURE 28TH FEBRUARY FRIDAY SYSTEMIC SCLEROSIS MORNING 08H30 – SECRETARIAT DESK OPENING 08H45 – WHAT DID WE LEARN YESTERDAY ? Maria João Oliveira| Lisbon, Portugal 09H00 – LECTURE Chair – Lèlita Santos| Coimbra, Portugal Muscle involvement in Systemic Sclerosis Luc Mouthon| Paris, France 09H30 – LECTURE SPONSORED BY OCTAPHARMA Chair – Edite Pereira| Porto, Portugal Primary Immunodeficiencies Bodo Grimbacher| London, UK 10H00 – ROUND TABLE SPONSORED BY ACTELION Activity markers in Systemic Sclerosis Chairman – Julio Sánchez-Román| Sevilla, Spain General evaluation of the activity markers Ignacio Martin Suárez| Huelva, Spain Specific evaluation of activity in Cutaneous and Articular involvement Isabel Almeida| Porto, Portugal Specific evaluation of activity in Cardio-pulmonary involvement Maria Jesús Castillo Palma| Sevilla, Spain 11H15 – COFFEE-BREAK 11H45 – LECTURE SPONSORED BY ASTRAZENECA Chairman – José Júlio Alves Moura| Coimbra, Portugal Cardiovascular Risk in Autoimmune Diseases Carlos Aguiar| Lisbon, Portugal 12H15 – LECTURE SPONSORED BY SANOFI-PASTEUR-MSD Chairman – António Sarmento| Porto, Portugal Infection and Vaccination by Zoster Virus in Elderly and Autoimmune Diseases Cândida Abreu| Porto,Portugal 12H45 – CASE REPORT 2 Chairman – Bernardo Sopeña| Vigo, Spain 40-years-old patient with Raynaud and tachycardia Case Report – Mayka Freire| Vigo, Spain Discussion – Cláudia Martins| Viseu, Portugal, Fernando Salvador| Vila Real, Portugal and Anabela Morais| Vila Real, Portugal 13H30 – LUNCH APS AND SLE AFTERNOON 14H30 – LECTURE SPONSORED BY BAYER Chair – Isabel Almeida| Porto, Portugal Digital ulcers: prediction, prevention and treatment in Systemic Sclerosis Ivone Silva| Porto, Portugal 15H00 – LECTURE SPONSORED BY BAYER Chair – Lúcia Costa| Porto, Portugal Pulmonary Hypertension in Systemic Sclerosis: is it possible to DETECT patients in NYHA class I or II? Rui Baptista| Coimbra, Portugal 15H30 – LECTURE Chairman – João Frazão| Porto, Portugal The role of nucleosomes in initiating glomerular lesions in SLE Jo Berden| Nijmegen, The Netherlands 16H00 – LECTURE Chairman – Nuno Riso| Lisbon, Portugal Mechanisms of Thrombosis in APS. What news? Anisur Rahman| London, Uk 16H30 – COFFEE-BREAK 17H00 – LECTURE SPONSORED BY GLAXOSMITHKLINE Chairman – Carlos Vasconcelos| Porto, Portugal Therapeutic targets in SLE: where do we stand? George Bertsias| Crete, Greece 17H30 – LECTURE Chairman – Guilherme Macedo| Porto, Portugal Genetics in Primary Biliary Cirrhosis in the GWAS era Pietro Invernizzi| Milan, Italy 18H00 – CASE REPORT 3 Chair – Gabriela Sousa Vinhas| Lisbon, Portugal Severe and Refractory Thrombocytopenia in a patient with SLE Case report – Lígia Peixoto and João Espírito Santo| Lisbon, Portugal Discussion – Joana Vedes| Guarda, Portugal, Deolinda Portelinha| Coimbra, Portugal and Ana Carolina Araújo| Lisbon, Portugal 18H45 – CLOSURE 01ST MARCH SATURDAY SYSTEMIC AUTOIMMUNE DISEASES MORNING 08H15 – SECRETARIAT DESK OPENING 08H45 – WHAT DID WE LEARN YESTERDAY? Tiago Borges| Porto, Portugal 09H00 – LECTURE SPONSORED BY OCTAPHARMA Chair – Paula Marques| Porto, Portugal A review on IVIG in Autoimmune Diseases Srini Kaveri| Paris, France 09H30 – LECTURE Chairman – Luís Campos| Lisbon, Portugal Sex and Autoimmune Diseases Carlo Selmi| Milan, Italy 10H00 – CASE REPORT 4 Chairman – Jorge Fortuna| Coimbra, Portugal Weight loss in a patient with BOOP and erythematous nodules Case report – Ricardo José da Cunha Marques| Coimbra, Portugal Discussion – Marina Bastos| Viseu, Portugal, Bruno Grima| Amadora, Portugal and Carla Noronha| Lisbon, Portugal 10H45 – COFFEE-BREAK 11H15 – LECTURE Chairman – Ricard Cervera| Barcelona, Spain APS and Pregnancy Jaume Alijotas Reig| Barcelona, Spain 11H45 – ROUND TABLE Uveitis – state of art President – Jorge Crespo| Coimbra, Portugal Chairs – Rui Proença| Coimbra, Portugal and Jorge Palmares| Porto, Portugal Uveitis management: what to Search Behind? Gerard Espinosa| Barcelona, Spain Refractory Uveitis: the role of Biological treatments Rui Proença| Coimbra, Portugal Posterior Uveitis Luís Torrão and Luís Figueira| Porto, Portugal 13H00 – CLOSURE LECTURE Chairman – Manuel Pizarro| Porto, Portugal Update in the treatment of ANCA-associated vasculitis Loic Guillevin| Paris, France 2nd Vasco da Gama Award For Explorations in Autoimmunity to Loic Guillevin 13H30 – FINAL LUNCH President Carlos Dias Honorary President Paulo Bettencourt Vice President Fátima Coelho General Secretary Cláudia Costa Scientific Coordinator Paula Vaz Marques Portuguese Scientific Committee Carlos Ferreira| Lisbon, Portugal Carlos Vasconcelos| Porto, Portugal João Pedro Ramos| Porto, Portugal Jorge Crespo| Coimbra, Portugal José Delgado Alves| Lisbon, Portugal Lèlita Santos| Coimbra, Portugal Luís Campos| Lisbon, Portugal Institutional Sponsor Scientific Sponsor Partners Platinum Sponsors Silver Sponsors Bronze Sponsors Design Eva Mendes and Joana de Rosa Gold Sponsors International Scientific Committee David D’Cruz| London, Portugal Munther Khamashta| London, England Yehuda Shoenfeld| Tel Aviv, Israel Ricard Cervera| Barcelona, Spain Dear Colleague, Medinterna Association, from Internal Medicine Service of Centro Hospitalar São João, is organizing the 12th International Meeting on Autoimmune Diseases, from 27th February to 1st March 2014, at Fundação Dr. António Cupertino de Miranda, Porto. The main goal of these meetings is to update the knowledge in the autoimmune diseases field and to create funds to promote and support post-graduate studies in Internal Medicine, mainly for residents. Autoimmune diseases are a challenge to physicians diagnosis skills and therapeutic strategies. Internal Medicine is recognized as one of the most vocated speciality for the approach of the multisystemic and multidisciplinary involvement of these diseases, which many times force to immediate and difficult decisions. It’s an area which development is in continuous progress, with new results and multiple clinical assays, originating therapeutical advances and controversial positions mainly on the diagnostic and therapeutic approach of SLE, APS, Behçet disease, ANCA-associated vasculitis, systemic sclerosis, rheumatoid arthritis, juvenile arthritis and other rheumatic diseasec and in the ever controversial use of the biological therapeutics. Scientific program counts on the participation of experts from France, Greece, Israel, Italy, Norway, Portugal, Spain, The Netherlands and United Kingdom. It will count on several clinical cases discussed by the audience and invited experts and also a summary of the most relevant facts of the previous day presented by an expert at the begining of each day. We hope that the chosen subjects may interest to everyone and that they bring something useful and new for the clinical practice. All the internists, rheumatologists, clinical pathologists and immunologists, specially residents, are welcome to participate in all the sessions. We thank the pharmaceutical industry that, with her support, helps and contributes to the success of these scientific events. We count on everyone’s presence. See you soon. Carlos Dias