DR-TB pacientebis mier samkurnalo reJimebis Sesruleba “samSabaToba” 29.06.10 cira Caxaia, TamTa komaxiZe mizani axali da warsulSi namkurnalebi pacientebis mier samkurnalo reJimebis Sesrulebis Sefaseba ganyofilebebisa da Tveebis mixedviT preparatebis mixedviT dozis im arasrulyofilad miRebis daxasiaTeba gamotovebuli dozebisa da dReebis arasrulad miRebis sixSiris gansazRvra preparatebis gamovlena, romelTa arasruli doziT miReba xdeba upiratesad mizani samkurnalo stacionarul reJimebis arasrulyofilad Sesrulebis mizezebis gansazRvra da ambulatoriul pirobebSi samkurnalo reJimebis Sesrulebis Sedareba kavSiris dadgena preparatebis arasrul miRebasa da DST profilis cvlilebas Soris asocirebuli kavSiris dadgena samkurnalo reJimis Sesrulebasa da mkurnalobis gamosavals Soris asocirebuli meTodologia wlis ianvarSi, TebervalSi, martsa da aprilSi gawerili DR-TB pacientebis monacemebi Segrovda da damuSavda tfdec-is I, III da V Terapiuli ganyofilebebidan (maisis monacemebi Tavad ganyofilebebma daamuSaves) 2010 monacemebi Segrovda pacientTa monacemebi Segrovda pacientTa mkurnalobis monitoringis formis safuZvelze; Seqmnili kiTxvaris daxmarebiT monacemebi damuSavda Epiinfo-s programiT specialurad kiTxvari samkurnalo reJimis Sesruleba srulyofilad CaiTvala, Tu Tvis ganmavlobaSi arcerTi preparati arcerTxel ar iyo gamotovebuli Tvis ganmavlobaSi erTi dozis gamotovebac ki arasrulyofil samkurnalo reJimad CaiTvala arasrulyofili samkurnalo reJimi daiyo: dozebis mixedviT – 1, 2, 3 da yvela preparatis gamotoveba dReebis mixedviT – 1-2, 3-9, 10 da meti dRis gamotoveba DR-T B PDR-TB N % 4 4,3% 80 87,0% 8 8,7% 92 100,0% MDR-TB XDR-TB sul MDR-TB SemTxvevebis ganawileba ganyofilebebis mixedviT axali da warsulSi I da II rigis TB preparatebiT namkurnalebi pacientebis sixSire SemTxveva N % axali 33 35.9% warsulSi namkurnalebi 59 64.1% sul 92 100.0% warsulSi namkurnalebi N % I 37 62.7% II 22 37.3% sul 59 100.0% axali da warsulSi namkurnalebi SemTxvevebis ganawileba ganyofilebebis mixedviT axali da warsulSi namkurnalebi pacientebis mier samkurnalo reJimis Sesruleba (ianvari) 100 10.2 90 80 47.6 70 srulyofilad (ianvari) 60 50 89.8 40 30 52.4 20 10 0 axali warsulSi namk. arasrulyofilad (ianvari) axali da warsulSi namkurnalebi pacientebis mier samkurnalo reJimis Sesruleba (Tebervali) 100 25 90 80 56.5 70 srulyofilad (Tebervali) 60 arasrulyofilad (Tebervali) 50 75 40 30 43.5 20 10 0 axali warsulSi namk. axali da warsulSi namkurnalebi pacientebis mier samkurnalo reJimis Sesruleba (marti) 100 26.9 90 80 65 70 srulyofilad (marti) 60 arasrulyofilad (marti) 50 73.1 40 30 35 20 10 0 axali warsulSi namk. axali da warsulSi namkurnalebi pacientebis mier samkurnalo reJimis Sesruleba (aprili) 100 90 0 22.2 80 70 srulyofilad (aprili) 60 50 40 100 77.8 30 20 10 0 axali warsulSi namk. arasrulyofilad (aprili) samkurnalo reJimis Sesrulebis dinamika Tveebis mixedviT 100.0% 88.9% 90.0% 80.0% 78.6% 70.0% 63.5% 56.5% 60.0% 50.0% 43.5% 20.0% 21.4% 11.1% 10.0% 0.0% arasrulyofilad 36.5% 40.0% 30.0% srulyofilad ianvari Tebervali marti aprili samkurnalo reJimis Sesruleba Tveebis mixedviT samkurnalo reJimis Sesruleba N (%) ianvari srulad N (%) Tebervali marti aprili 23 (36.5%) 20 (43.5%) 15 (21.4%) 2 (11.1%) arasrulad 55 (78.6%) 40 (63.5%) 26 (56.5%) 16 (88.9%) sul 70 (100%) 63 (100%) 46 (100%) 18 (100%) samkurnalo reJimis Sesruleba ganyofilebebis mixedviT (ianvari) 100 11.8 18.5 90 30.8 80 70 60 ianvari-srulyofilad 50 ianvari-arasrulyofilad 88.2 81.5 40 69.2 30 20 10 0 I III V samkurnalo reJimis Sesruleba ganyofilebebis mixedviT (Tebervali) 100 13.3 90 36.4 80 50 70 60 Tebervali-srulyofilad 50 Tebervali-arasrulyofilad 86.7 40 63.6 30 50 20 10 0 I III V samkurnalo reJimis Sesruleba ganyofilebebis mixedviT (marti) 100 21.4 90 41.2 80 66.7 70 60 marti-srulyofilad 50 marti-arasrulyofilad 78.6 40 58.8 30 33.3 20 10 0 I III V samkurnalo reJimis Sesruleba ganyofilebebis mixedviT (aprili) 100 11.1 90 0 16.7 80 70 aprili-srulyofilad 60 50 88.9 40 100 83.3 30 20 10 0 I III V aprili-arasrulyofilad yvela preparatis gamotoveba erTipreparatis gamotoveba ori preparatis gamotoveba sami preparatis gamotoveba samze meti, magram arayvela preparatis gamotoveba PAS-is gamotoveba Tveebis mixedviT 30.0% 27.8% 25.0% 20.0% 15.0% 20.0% 20.6% 18.6% 19.6% 17.5% 16.7% 15.2% 12.9% 10->10 1-2 dRe 12.7% 3-9 dRe 10.0% 8.7% 5.6% 5.0% 0.0% ianvari Tebervali marti aprili Pto-is gamotoveba Tveebis mixedviT 14.0% 12.7% 12.0% 10.0% 8.7% 8.0% 6.0% 7.1%7.1% 5.7% 10->10 6.5% 6.3% 5.6%5.6% 4.3% 4.0% 3.2% 2.0% 0.0% 0.0% ianvari Tebervali marti aprili 1-2dRe 3-9dRe daskvna axal SemTxvevebTan SedarebiT warsulSi namkurnalebi pacientebi samkurnalo reJims gacilebiT ufro xSirad arRveven gacilebiT xSiria preparatebis arasrulyofilad miReba reJimebis arasrulad Sesrulebis SemTxvevebSi sWarbobs 1, 2, an 3 preparatis 1-2 da 3-9 dRis ganmavlobaSi gamotovebis sixSire Tveebis mixedviT samkurnalo reJimebis Sesruleba gansxvavebuli da arastabiluria rogorc mosalodneli iyo upiratesad xdeba PAS-is da Pto-is dozebis da dReebis mixedviT gamotoveba preparatebis srulyofilad da arasrulyofilad miRebis sixSire ganyofilebebis mixedviT (maisi, 2010) 70% 60% 58% 57% 60% 50% 42% 40% 43% 40% srulyofili arasrulyofili 30% 20% 10% 0% I III V preparatebis xarjva (I Terapiuli gany.) 90% 89% 86% 90% 81% 86% 77% 80% 70% 84% 65% 60% 50% miRebuli gamotovebuli 40% 35% 30% 23% 19% 20% 14% 11% 16% 14% 10% 10% 0% R E Z Cm Lfx Pto PAS Cs preparatebis xarjva (III Terapiuli gany.) 100% 93% 90% 88% 86% 88% 88% 90% 88% 87% 86% 81% 80% 68% 70% 60% 50% gamotovebuli 40% 32% 30% 19% 20% 14% 12% 12% 12% 14% 12% 13% 10% 7% 10% 0% E Z Cm Lfx Mfx Pto Cs PAS Amx/Clv Clr Cfz preparatebis xarjva (III Terapiuli gany.) 100% 93% 91% 86% 90% 87% 88% 79% 80% 78% 75% 78% 70% 60% miRebuli 50% gamotovebuli 40% 30% 21% 20% 10% 14% 7% 13% 9% 22% 25% 22% 12% 0% Cm Lfx Mfx Pto Cs PAS Amx/Clv Clr Cfz Cm-is gamotovebis mizezebis sixSire (I Terapia) Cm 83% 90% 80% 70% 60% 50% 40% 30% 20% 15% 2% 10% 0% ar iyo gv. Mov sxva miz. PAS-is gamotovebis mizezebis sixSire (III Terapia) 83% 90% 80% 70% 60% 50% 40% 30% 20% 15% 2% 10% 0% ar iyo gv. Mov sxva miz. preparatebis gamotovebis mizezebis sixSire (V Terapia) 70% 64%65% 60% 50% 40% 36% 36% 32% 29% 25% 21% 30% 24% 30% Cfz 11% 0% 6% 5% 4% ar iyo 6% 4% 2% gv.mov. Tan.daav SeC Amx/Clv Clr 20% 10% PAS sxva gmadlobT yuradRebisaTvis