Maria Adilia Januário Charmier Curriculum vitae 2014 1 Maria Adilia Januário Charmier 1. PERSONAL DATA Full name: Maria Adilia Januário Charmier Birth date : 24 April 1962 Place of birth: Fundão (Portugal) Nationality: Franco-Portuguese Education : PhD (1993, Université Blaise Pascal, France) Present position : Full Professor, Universidade Lusófona de Humanidades e Tecnologias ULHT, School of Engineering Personal address: Rua Tomás de Figueiredo, nº 27, Vale Fetal, 2820-453, Charneca da Caparica, Portugal Institutional Universidade Lusófona de Humanidades e Tecnologias (ULHT), Av. addresses: Campo Grande 376, 1749-024 Lisboa Centro de Química Estrutural, Complexo I, Instituto Superior Técnico, Av. Rovisco Pais, 1049-001 Lisboa Telf. 218419225 / 35. Tele: +351-218 419 225 (lab) or 207 (office). Contacts : [email protected] [email protected] URL http://cqe.ist.utl.pt [email protected] URL http://www.ulusofona.pt 2. ACADEMIC DEGREES 1993 : Ph.D in Organic Chemistry, Université Blaise Pascal, ClermontFerrand l988 : (France). Diplôme d’Etudes Approfondies D.E.A de Chimie, Université Blaise Pascal. 2 Maria Adilia Januário Charmier 1987 : Maîtrise-és-Sciences, Université Blaise Pascal. 1986 : Licence-és-Sciences, Université Blaise Pascal. 1984 : DEUG B (Diplôme d´Études Universitaire Générales), option Biochimie, Université Blaise Pascal. 3. PREVIOUS ACTIVITY AND CURRENT STATUS 2013-present : Full Professor, Universidade Lusófona de Humanidades e Tecnologias (ULHT). 1994-2012 : Associate Professor, ULHT. 2014-2016 : Principal researcher for the implementation of a extraction pilot plant station in Portugal in collaboration with the Food supplements Company CEREBIO, Coutras, France. [email protected] 2014 – 2015 : Scientific and Pedagogical Director of the Advanced Studies Center of Setubal, CEAS, (Postgraduate courses), ULHT. 2011-present : Coordinator of the Biotechnology Engineering Department (Bachelor, Master, Postgraduate Forensic Genetics, Postgraduate clinical and laboratory Genetics courses), ULHT. 2009-present : Director of the Research Center in Biology, Biotechnology and Biomedicine (CB3) at the School of Engineering, ULHT. 2008-present : Director of the Undergraduate Biotechnology Engineering course, ULHT. 2007-2012 : Director of the Undergraduate Chemistry Engineering course and Post-graduate course of Chemistry of Essential oils, ULHT. 2002-present : Member of the research Center CQE, Centro de Química Estrutural, grupo V), Instituto Superior Técnico IST, Lisbon. 2012-present : Member of the Portuguese Society of Chemistry. 1994-2002 : Associate member of the Research Center CQFB, UNL (Centro de Química Fina e Biológica, Requinte), Universidade Nova de Lisboa, Monte da Caparica, UNL . 1994-1996 : Postdoctoral fellowship grant, Faculdade de Ciências e Tecnologias , Universidade Nova de Lisboa, FCT-UNL. 3 Maria Adilia Januário Charmier 1993-1994 : Postdoctoral Erasmus grant at ITQB (Instituto de Tecnologia Química e Biológica). 1992-1993: Researcher and Teacher, École Nationale Supérieure de Chimie de Clermont-Ferrand (ENSCCF) , France. 4. CURRENT RESEARCH INTERESTS The main research area and interest are the study of reactions in Organic Chemistry applied to the coordinated-metal complexes Chemistry, using “green” technologies as microwave irradiation for the synthesis of novel compounds as tetrazoles, triazoles, azides, lactams….and the study of their biological properties. Others interests are the use of the microwave irradiation technology in the extraction of essential oils and extracts from plants, fruits, olive wastes, beer, wine with characterization of the obtained natural products, their chemical functionalisation as well as the study of their biological properties (antioxidant, antibacterial, antitumoral, antidepressive) and the development of innovative final products applied against hospitalar infections, diseases treatment and with interests in food, cosmetics industries as well as environmental applications. Scientific Areas of Interest: Organic Ligands reactivity, metal-mediated organic synthesis, Coordination chemistry in cycloaddition reactions, catalysis, heterocycles, Microwave assisted-promoted synthesis, extraction of plants, antimicrobial and antioxidant activity. 5- CURRENT AND PREVIOUS ACTIVITIES RELATED TO TEACHING Lecturing 2013-present : Full Professor, School of Engineering, ULHT, of the following modules : Organic Chemistry General Chemistry I Chemistry of Natural Products (in undergraduate Biotechnology course) Advanced Chemistry of Natural Products (in Master in Engineering Biotechnology) Chemistry and Biochemistry (Postgraduate course of Oenology) 2012-2014 Associate Professor and Full Professor (2013-2014) School of Psychology and Life Sciences of the module : 4 Maria Adilia Januário Charmier Fundaments of Life : Chemistry 1994-2013 : Associate Professor, School of Engineering, ULHT, of the following modules : Organic Chemistry I Chemistry I Chemistry of Natural Products (2012-2103) (undergraduate Biotechnology course) Advanced Chemistry of Natural Products (2012-2103) (Master in Engineering Biotechnology) General Chemistry Organic Chemistry II Advanced Organic synthesis (in undergraduate Chemistry course) Chemical Analysis (in undergraduate Chemistry course) Analytical Chemistry 2008-2012 : Associate Professor, Faculty of Biomedical Sciences, ULHT of the module : Fundamentals of Life : Chemistry 2001-2013 : Associate Professor, School of Engineering, ULHT : Life Science-Science on Holidays –Chemistry applied to Health 1992-1993 : ATER, École Nationale Supérieure de Chimie de Clermont-Ferrand (ENSCCF) , France Chimie Organique Olympiades de la Chimie, Université Blaise Pascal. 5. SUPERVISING EXPERIENCE 5.1-Bachelor- Master- PhD- Postdoctoral Thesis 2013-2016 : Supervisor of PhD thesis, Sergiy Lyubchik, Program Erasmus Mundus, Research Centro de Química Estrutural (CQE), Instituto Superior Técnico (IST). 2012-2014 : Supervisor of Master theses, Humanidades e Tecnologias ULHT. 2005-2010 : Supervisor of 2 Post-doctoral researchers Dr. Jamal Lasri (3 years), Universidade Lusófona 5 Maria Adilia Januário Charmier de Dr. Suman Mukhopadhyay (3 years) and a Postgraduate researcher Dra. Bhaswati Mukhopadhyay (1 year). 1996-2008 : Supervisor of theses to obtain the Bachelor degree (Licenciatura) in Biotechnology and Environment Engineering courses at Universidade Lusófona de Humanidades e Tecnologias ULHT. 1996-2003 : Supervisor of Postdoctoral researcher Dr. Thierry Michaud, Centro de Química Fina e Biológica (CQFB-UNL), ITQB, Lisbon 1994-2001 : Supervisor of theses to obtain the Bachelor degree (Licenciatura) in Chemistry, Centro de Química Fina e Biológica (CQFB) na Universidade Nova de UNL, Lisbon 5.2-Member of Juries 1996-present : Member of the jury of Graduation theses and Master theses at ULHT (Biotechnology and Environment Engineering courses). 2006-2007 : Member of the jury of 2 PhD theses of graduated students in Chemical Engineering (Russia), Instituto Superior Técnico (IST). 6. OTHERS AREAS 2001-Present : Researcher and Professor : project “Life Science on Holidays “ (Ciência Viva nas férias) –Chemistry applied to Health “A Química na Saúde”, developed at ULHT and sponsored by the Ministry for Science and Technology. This annual program allows secondary level students to spend one week in July at the University performing experiments supervised by researchers. 2000-Present : One of the creators of the Program “Create Knowledge”-“Criar Saberes”. Responsible of the area of Chemistry. Each week, during all the academic year, the University ULHT receive secondary schools. The students visit the university and are introduced to laboratory activities. 6 Maria Adilia Januário Charmier 2-8 September 2012 : Member of the organizing committee of "International Conference on Organometallic Chemistry” (XXV ICOMC), Lisbon. 3 June 2012 : Organizer of “ Journeys of CB3, taste session of olive oil, beer, sensory analysis”- “Jornadas do CB3, Provas de azeite, vinho, cerveja, Análise sensorial”, , Faculdade de Engenharias e Ciências Naturais (FECN) , Centro de investigação de Biologia, Biotecnologia, Biomedicina (CB3), Universidade Lusófona de Humanidades e Tecnologias (ULHT) – sponsored by the Companies Central de Cervejas Heinenken group and Penazeite. 17 March 2011 : Organizer member of “The week of FECN- First forum of Biotechnology and Environmental Engineering” - "Semana da FECN - I Fórum de Eng.ª Biotecnológica e Eng.ª do Ambiente Atelier of Cosmetics” sponsored by the company Elisa da Câmara Lda, Faculdade de Engenharias e Ciências Naturais (FECN) , Universidade Lusófona de Humanidades e Tecnologias (ULHT) 12-14 of April 2010 : Organizer of the second cycle of Conferences in ULHT “New technologies nowadays”, special gest from France Christophe Janicot, Director of the company of Cosmetics NATUREA and of Food supplements CEREBIO, Coutras, France. 11-20 of April 2009 : Organizer of the first cycle of Conferences in ULHT “ Research nowadays in Biotechnology, Environment, Biology and Chemistry”, Universidade Lusófona de Humanidades e Tecnologias, Faculdade de Engenharias e Ciências Naturais (FECN) 7. PARTICIPATION IN RESEARCH PROJECTS 2015-2017 : Coordinator and researcher of the project : “Research and development of plants extraction using microwave and supercritical technologies”, pilot station in Portugal will be implemented and financed by the company CEREBIO, Coutras, France. 2013-2016 : Coordinator of the project ERASMUS MUNDUS “Extraction of natural products via microwave technology. Characterization and Complexation with metals. Potential antibacterial and antitumoral compounds”.(supervision of a PhD student). 7 Maria Adilia Januário Charmier 2013-2014 : Supervisor and researcher, projecto: “Study of the anti-bacterial and anti-tumoral properties from extracts and essential oils and their application against hospitalar infections”, (supervisor of a Master student). 2012-2014 : Creation and production of a new Beer “CUL” without diacetyl: enzimatic process and NIR (SpectraAlizer)”, pilot station, ULHT. 2011-2012 : Principal Researcher (PI) of the project QREN, “Recovery, recycling and reuse of wastes from the oil industry and natural resources through advanced techniques of extraction”, Instituition COFAC (CB3), ULHT / company PENAZEITE (Penamacor). 2005-2010 : Principal Researcher (PI) of the project reference POCTI/QUI/59558/2004 financed by the Foundation of Sciences and Tecnology FCT., “Synthesis of new heterocycles with biological properties : reactions of cycloaddition of various dipoles with metal-coordinated organonitriles by microwave irradiation”, Coordinator : Professor Dr.A. Pombeiro, Group V, CQE, IST, Lisbon. 2008-2009 : Principal researcher (PI) " Cistus ladanifer (esteva): Dupla valorização dos extractos e óleos essenciais na indústria dermocosmética e fotoprotectores. Fonte de complexos metálicos com propriedades Biológicas e nova alternativa na descontaminação de metais do solo " .PTDC/AGRAAM/100280/2008. 1999- 2001 : Researcher, Project "Microwave and Metal-Assisted Stereoselective [2+3] Cycloadditions of Dipoles to Organodipolarophiles: Synthesis of biological Heterocycles" , UNL, Lisbon. 1997-2000 : Researcher, project “Synthesis of lactams via 1,3-dipolar cycloadditions of nitrones and nitriles oxides and other additions to chiral enoates with allylic alcohols” in collaboration with Professor Dr. T. Barros, UNL, Universidade Nova de Lisboa, financed by the Program PRAXIS by J.N.I.C.T. 1994-1996 : Postdoctoral fellowship, “Stereoselective Synthesis of Polyhydroxylated Piperidin-2-ones and diaminoalcohols”, ITQB, Supervised by Professor Dr. C. D. Maycock. 8 Maria Adilia Januário Charmier 1989-1993 : Researcher, PhD Thesis title : “Cycloaditions dipolaires-1,3 de nitrones et de nitriloxydes sur des olefines captodatives, crotoniques et vinylacétiques. Obtention d'aminoalcools, cyclisation en lactames”. PhD fellowship grant awarded By le Ministére d’Education Nationale, France. 8. PAPERS IN INTERNATIONAL SCIENTIFIC PERIODICALS WITH REFEREES 1-“1,3-Dipolar Cycloaddition Reaction of Nitriles Oxides with Chiral Vinylacetic Olefin In Racemic Series”, J. Chanet, S. Chou, M.O. Januário-Charmier, and R.Vessière, J. Chem. Research (S), 1994, 382-383. 2-“1,3-Dipolar Cycloaddition Reaction of Nitrones with Chiral Vinylacetic Olefins In Racemic Series, Synthesis of -Lactams via Isoxazolidines, J. Chanet, M. O. Januário Charmier, R.Vessière, and M.F. Zuccarelli, J. Heterocyclic. Chem., 1994, 31, 16671671. 3-“Chemoselectivity in the Manipulation of Polyhydroxylated Compounds Derived from the Diastereoselective Dihydroxylation of Optically Active Allylic Enoate Alcohols”, M.T. Barros, M.O. Januário-Charmier, M. Pires and C.D. Maycock Tetrahedron, 1996, 52, 7861-7874. 4-“1,3-Dipolar Cycloaddition Reaction of Nitrones with Unsaturated Methylsulfones and Substituted Crotonic Esters", M.O. Januario-Charmier*, N. Moussalli, J. Chanet and S. Chou, , J. Chem. Research (S), 1999, 566-567. 5- "An Expedient Stereoselective Synthesis of Polyhydroxylated Piperidin-2-ones", M. T. Barros, M.A. Januário-Charmier, C. D. Maycock and T. Michaud, Tetrahedron, 2002, 58, 1519. 6- "Microwave-Assisted [2+3] Cycloaddition of Nitrones to Platinum(II) and (IV)bound Organonitriles", M.Adília Januário-Charmier*, Vadim Yu. Kukushkin, and Armando J. L. Pombeiro, J. Chem. Soc., Dalton Trans, 2003, 12, 2540. 7- "Unprecedented Single-pot Synthesis of Keto Imino Platinum (II) Complexes from Nitriles complexes by Ring Opening of 1, 2, 4-Oxadiazoline", M.Adília Januário Charmier*, Matti Hauka and Armando J. L. Pombeiro, J. Chem. Soc., Dalton Trans, 2004, 2741-2745. 9 Maria Adilia Januário Charmier 8- "Stereoselective Synthesis of Optically Active Mono and Diaminoalcohols” M. T. Barros, M. A. Januário Charmier, C. D. Maycock and T. Michaud, Tetrahedron, 2005, 61, 7960-7966. 9- "Direct Synthesis of (Imine)Platinum(II) Complexes by Iminoacylation of Ketoximes with Activated Organonitriles Ligands", J. Lasri, M. A. Januário-Charmier*, M. F. Guedes da Silva and Armando J. L. Pombeiro*, Dalton Trans, 2006, 5062-5067. DOI: 10.1039/b611341a 10- "Stereospecific Synthesis of Polysubstituted E- Olefins by Reaction of Acyclic Nitrones with Free and Platinum(II) Coordinated Organonitriles", J. Lasri, M. A. Januário Charmier*, Matti Haukka, and A. J. L. Pombeiro*, J. Org. Chem., 2007, 72, 750-755. 11- "Mixed Unsymmetric Oxadiazoline and/or-Imine Platinum(II)Complexes", J. Lasri, M. A. Januário Charmier*, M.F. Guedes da Silva and A. J. L. Pombeiro*, Dalton Trans, 2007, 3259. DOI: 10.1039/b704329e. 12- “Optically Active Mixed Unsymmetric Imine Platinum(II) Complexes. Utilization of the Liberated Imines to Further Syntheses of Mixed Imine-Diazadiene Complexes and of E-cyanoalkanes”, J. Lasri, M.F.C. Guedes da Silva, M.A. Charmier*, A.J.L. Pombeiro, Eur. J. Inorg. Chem., 2007, 3668-3677. 13- "Microwave Synthesis of Mono- and Bis-Tetrazole Complexes via 1,3-Dipolar Cycloaddition of Organonitriles with Platinum(II)Azides", S. Mukhopadhyay, J. Lasri, M. A. Januário Charmier*, M.F. Guedes da Silva and A. J. L. Pombeiro*, Dalton Trans. 2007, 5297. DOI: 10.1039/b709959b14-"Trans-Bis(triphenylphosphine)-bis{5-(4-fluorophenyl)-2H-tetrazolatoN2}platinum (II)", Mukhopadhyay, S.; Lasri, J. Januário Charmier*, M. A. J.; Guedes da Silva, M. F. C.; Pombeiro, A.J.L.–Acta Cryst. 2007, E63,m2656.Doi: 10.1107/S1600536807047617. 15-“Metal-free and PdII-promoted [2+3] Cycloadditions of Cyclic Nitrone to Phthalonitriles: Syntheses of Oxadiazolines, Phthalamides and Dihydropyrrolyliminoisoindolinone PdII Complexes. High Catalytic Activity of the PdII Complexes for the Suzuki-Miyaura Cross-Coupling”, J. Lasri, M.N. Kopylovich, M.F.C. Guedes da Silva, M.A. Januário Charmier, A.J.L. Pombeiro*, Chem. Eur. J., 2008, 14, 9312-9322. DOI: 10.1002/chem.200800510. 16- "Efficient regioselective synthesis of 4- and 5-substituted isoxazoles", Lasri, J.; Mukhopadhyay, S.; Januário Charmier*, M. A. – J. Heterocyclic. chem., 2008, 1385. 17- "Activation of C-CN bond of propionitrile : an alternative route to synthesize 5substituted-1H-tetrazoles and dicyano- platinum(II) complex", Mukhopadhyay, S.; 10 Maria Adilia Januário Charmier Lasri, J.; Januário Charmier*, M. A.; Guedes da Silva, M. F. C.; Pombeiro, A. J. L. – Polyhedron., 2008, 2883. 18- "New Water-soluble Azido- and Derived Tetrazolato-platinum(II) Complexes with 1,3,5-triaza-7-phosphaadamantane (PTA). Easy Metal-mediated Synthesis and Isolation, from Aqueous Medium, of 5- substituted Tetrazoles”, P. Smolenski, S. Mukhopadhyaya, M.F.C. Guedes da Silva, M.A. Januário Charmier, A.J.L. Pombeiro*, Dalton Trans., 2008, 6546. DOI: 10.1039/b808156e. 19- "PtII-promoted [2+3] cycloaddition of azide to cyanopyridines: convenient tool toward heterometallic structures", Mukhopadhyay, S.; Ghosh Mukhopadhyay, B.; Guedes da Silva, M. F. C.; Lasri, J.; Januário Charmier*, M. A..; Pombeiro, A. J. L., Inorg. Chem. , 2008, 47, 11334. Doi: 10.1021/ic8014223. 20- "PdII-promoted [2+3] cycloaddition of Pyrrolin N-oxide to organonitriles. Application of fused bicyclic (1,2,4-oxadiazoline)-PdII Complexes in the MicrowaveAssisted Suzuki-Miyaura Cross-Coupling in Aqueous Medium", Lasri, J.; Kopylovich, M. N.; Guedes da Silva, M. F. C.; Mukhopadhyay, S.; Januário Charmier, M. A. ; Pombeiro, A. J. L., Dalton Trans., 2009. DOI:10.1039/b813996b. 21- “Synthesis of mono- and bis-tetrazolato complexes of Ni(II), Pt(II) and Cu(II) via 1,3-dipolar cycloadditions of 2-cyanopyridines with metal ligated azides in N,N,Oaminoiminophenolato complexes”, Mukhopadhyay, S. Mukhopadhyay, M.F.C. Guedes da Silva, M.A. Januário Charmier*, A.J. L. Pombeiro, Dalton Trans, 2009, 4778–4785. http://dx.doi.org/10.1039/b902007a. 22- “Synthesis of Lactones by desymmetrization. A synthesis of (-) muricatacin”, M. T. Barros, M. A. Januário Charmier*, C. D. Maycock, T. Thierry, Tetrahedron, 2009, 65, 396-399. Doi: 10.1016/j.tet-2008.10.020. 23-“Characterization of the antiproliferatrive potential and biological targets of trans ketoimine platinum complex”, Joana Silva, António Sebastião Rodrigues, Paula A. Videira, Jamal Lasri, M.Adília Januário Charmier, Armando J.L. Pombeiro, and Alexandra R. Fernandes, Inorganic Chimica Acta, 2014, in press. DOI: 10.1016/j.ica.2014.07.067. 24-“Interaction of cis-[Pt(N3)2(PPh3)2] with Different Alkenenitriles : Cycloaddition and Unusual Activation of Carbon-Carbon Bonds”, S. Mukhopadhyay, B. Ghosh Mukhopadhyay , M. Fátima C. Guedes da Silva, M. A. Januário Charmier*, and A. J. L. submitted, Pombeiro*, 2014. PAPERS IN PREPARATION 11 Maria Adilia Januário Charmier 25- "Zinc complexes derived from tridentate Schiff-base Ligand : Synthesis, Structure, luminescence and biological properties", Mriganka Das, Poulami Mondal, Shaikh M Mobin, Maria Adilia Januário Charmier, Lucie Charmier, Suman Mukhopadhyay, 2014. 26- “ Extraction of natural products with potential activity against bacteria –“old problems and new solutions-”, Maria Adilia Januário Charmier, Marta Martins, Opinion article, Frontiers of Microbiology, 2014. 27-“Study of the anti-bacterial and anti-tumoral properties of oregano extracts and essential oils against hospitalar infections”, Susana Morgado, Marta Martins, Maria Adilia Januário Charmier, 2014. PATENTES : 1- Patent PT 103888 ( priority date 2007/11/20) "System and Method of synthesis of polysubstituted E-cyanolefins based on reactions of nitriles with nitrones", A.J.L.Pombeiro, J.Lasri, M.A. Januário Charmier, M.Haukka. 2- Patent PT 104187 (data de prioridade: 2008/09/25; data da concessão: 2009/07/23) " New palladium complexes with bis(pyrrodinylledene) phthalamides and di hydropyrrolyliminoisoindolinones, and their application as catalysts in Suzuki-Miyaura coupling reactions", A.J.L.Pombeiro, J.Lasri, M.Kopylovich, M.F.C.Guedes da Silva, R.R.Fernandes, M.A.Januario Charmier. 3- Patent PT 104199 (data de prioridade 30/09/2008, data da concessão: 2009/08/11) "Novos complexos de paladio com ligandos bibíclos de tipo hidropirrolooxadiazole, e sua aplicação como catalisadores em reacções de acoplamento de Suzuki-Miyaura, assistidas por microondas", Pombeiro, A. J. L.; Lasri, J.;Kopylovich, M. N.;Guedes da Silva, M. F. C.; Mukhopadhyay, S.; Fernandes R.; Januário Charmier, M. A. 9. POSTERS IN CONFERENCES 1-“Stereoselective Synthesis of Polyols via Catalytic Mono-Dihydroxylation of di- and dienoate Compounds“, M. T. Barros, M. A. Januário Charmier, C. D. Maycock and T. Michaud, First Congress of Organic Chemistry, Braga, Portugal, 13-15 July 1995. 2-“Reacções de Cicloadição Dipolares-1,3 de Nitronas com Poliois Mono e Bis Alílicos e sua Aplicação na Síntese de Compostos com Actividade Biológica”, M. T. Barros, M. A. Januário Charmier, C. D. Maycock and T. Michaud,, First Congress of Organic Chemistry, Braga, Portugal, 13-15 July 1995. 3- “1,3-Dipolar Cycloaddition Reactions of Nitrones with Optically Active Allylic Enoate alcohols and Synthesis of Lactams via Aminoalcohols “,M. T. Barros, M. A. 12 Maria Adilia Januário Charmier Januário Charmier, C. D. Maycock and T. Michaud, second Congress of Organic Chemistry, Oeiras, 16-19 Setembro 1997. 4- “Selective Synthesis and structural Chemistry “, Requinte CQFB-CEQUP, first Meeting, Porto, 5-6 Fevereiro 1999. 5- “Stereoselective Synthesis of Optically Active Polyhydroxylated AminoAlcohols and DiaminoAlcohols”, M. T. Barros, M. A. Januário Charmier, C. D. Maycock and T. Michaud,Congress in Florida, USA, 22-25 de Novembro 2002. 6- “Microwave-Assisted [2+3] Cycloaddition of Nitrones to Platinum Organonitriles : A Promising Synthesis of New Biological Active Oxadiazolines and Ketoimines”, III Euchem Conference on NITROGEN LIGANDS IN ORGANOMETALLIC 7- “Direct synthesis of (imine)Pt(II) complexes by iminoacylation of Ketoximes with activated platinum(II)-coordinated organonitriles", J. Lasri, M. A. Januario Charmier, A. Pombeiro, Netherland´ Catalysis and Chemistry Conference, Amsterdam, March 2006. 8)-"Stereospecific synthesis of Polysubstituted E-Olefins by reaction of Acyclic Nitrones with Free and Platinum(II) Coordinated Organonitriles", J. Lasri, M. A. Januario Charmier, A. Pombeiro, Netherland´ Catalysis and Chemistry Conference, Amsterdam, March 2007. 9-“Mixed Unsymmetrical Oxadiazoline and/or Imino Platinum(II) Complexes”, J. Lasri, M.A.J. Charmier, M.F.C. Guedes da Silva, A.J.L. Pombeiro, IXth Netherlands’ Catalysis and Chemistry Conference, Noordwijkerhout, The Netherlands, 2008, P71, p.223. 10-“Platinum(II) Mediated [2+3] Cycloaddition of Azide and Nitrile: a Conveniente Tool towards Heterometallic Supramolecular Chemistry”, S. Mukhopadhyay, M.A.J. Charmier, M.F.C. Guedes da Silva, A.J.L. Pombeiro, 1st International Conference on Metal-Organic Frameworks and Open Framework Compounds (MOF08), Angsburg, Germany, 2008, P21, p.102. 11-" Interaction of cis-[Pt(N3)2(PPh3)2] with Different Alkenenitriles : Cycloaddition and Unusual Activation of Carbon-Carbon Bonds" Suman Mukhopadhyay and M. Adília Januário Charmier póster apresentado no congresso "FRONTIERS IN INORGANIC CHEMISTRY – 2010 " held in Indian Association for the Cultivation of Science, Kolkata, India on 11th December - 13th December, 2010. 12-“Characterization of the biological properties of new platinum complexes”, J. F. Silva, A. C. Silva, D. V. Luísa, S. Santosa, P. M. Borralho, C. M. Rodrigues, G. Cabralf, P. Videira, A.S. Rodrigues, J. Lasri, A. Januário Charmier, M.F. C. Guedes da 13 Maria Adilia Januário Charmier Silva, A. Pombeiro, A. R. Fernandes, XXV ICOMC, XXV International Conference of Organometallic Chemistry), Lisbon, 2-8 September 2012. 13- “Cerveja sem diacetilo: processamento enzimático e NIR (SpectraAlizer)”, M. A. Januário Charmier, N. Bravo, A. Tavares, L. Vasconcelos, e P. Fernandes, 16-19 September 2012, 11º congresso of the Chemistry of Food, Bragança. 14-Cycle of conferences “The cycle of life, Applied Kinesiology”, 20-25 de September de 2012, Montreal, Canada. 15-“Antiproliferative potential and biological targets of new platinum complex and their applications”, J. F. Silva, A. C. Silva, D.V. Luísa, S. Santosa, P. M. Borralho, C. M. Rodriguese, G.Cabralf, P.Videira, A.S.Rodrigues, J.Lasri, A.Charmier, M.F. C.Guedes da Silva, A.Pombeiro, A. R. Fernandes, 20th EuCheMS Conference on Organometallic Chemistry), St Andrews, Escócia, 1-5 July 2013. 16- “ Determination of Alcohol, pH and Density in Portuguese wines using a Method of Near-infrared (NIR”), Bravo N, Januário Charmier A, Gama, V, Jeremias, P.: IN VINO ANALYTICA SCIENTIA, 2-5 July 2013, Reims, France. 17- International Congress of Stévia “ Stevia Tasteful 2014 ”, M. Adilia Januário Charmier, Berlin, Germany, 19-20 June, 2014. 18- “Synthesis, Characterization and Antibacterial, Antioxidant and Antitumoral Evaluations of Novel Zn(II) Schiff Bases and Flavonoids Derivatives Complexes “, Januário Charmier M.A., Mukhopadhyay S., Sutradhar M. , Morgado S, Charmier L. , Pombeiro. A.J.L, AGICHEM, 9th Anglo-German Conference on Inorganic Chemistry, Edinburgh, July 30 – August 1st, 2014. Presenting author : M.A. Januário Charmier 10. LANGUAGE SKILLS French : Native (mother tongue) Portuguese : Native (mother tongue) English : Fluent in speech, writing and reading Spanish : Fluent in speech, moderate writing and reading 14 Maria Adilia Januário Charmier