2nd INTERNATIONAL PORTO CONGRESS OF MULTIPLE SCLEROSIS
25-26 January 2013
Ordem dos Médicos, Porto
Organizing Committee:
Maria José Sá, MD, PhD (President)
Jorge Reis, MD (Vice-president)
Joana Guimarães, MD
Pedro Abreu, MD
Teresa Mendonça, MD
Lucinda Sequeira (Secretary)
Institutional Departments:
MS Clinic, Dept. of Neurology, Centro Hospitalar São João, Porto
CSF Lab, Dept. of Neurology, Centro Hospitalar São João, Porto
Associação para a Investigação do LCR-HSJ, Porto
FRIDAY, 25 JANUARY 2013
ALL SESSIONS | 09h00 – 17h00 | ROOM SALÃO NOBRE
9h00
9h15 – 11h00
WELCOME ADDRESS
Maria José Sá, Centro Hospitalar São João, Porto, Health Sciences Faculty,
University Fernando Pessoa, Porto
SESSION 1 MS and Neuroimmunology
Chairpersons:
Armando Sena, Hospital dos Capuchos, Lisboa and Maria do Carmo Macário,
Centro Hospitalar Universitário de Coimbra
The cytokines network in MS relapses and the impact of high dose
intravenous methylprednisolone
Christian Sindic, Dept. of Neurology, Cliniques Universitaires Saint-Luc, Brussels,
Belgium
Autoimmunity and MS
Thomas Berger, Multiple Sclerosis Clinic, Clinical Dept. of Neurology, Innsbruck
Medical University, Austria
Update in body fluid markers
Gavin Giovannoni, Blizard Institute of Cell and Molecular Science, Barts and The
London School of Medicine and Dentistry, Queen Mary University of London, UK
1
11h00 – 11h30
Coffee Break | Exhibition Hall | Poster view
11h30 – 13h30
SESSION 2 MS, a complex disease
Chairpersons:
Maria José Sá, Centro Hospitalar São João, Porto, Health Sciences Faculty,
University Fernando Pessoa, Porto and José Vale, Hospital Beatriz Ângelo,
Loures
Evidence for Disease Heterogeneity in MS: Update on Controversy
Cláudia Lucchinetti, Dept. of Neurology, Mayo Clinic College of Medicine,
Rochester, USA
Clinical and imaging pitfalls in MS diagnosis
Mar Tintoré, Unitat de Neuroimmunologia Clinica (UNIC), Hospital Universitari
Vall d'Hebron, Barcelona, Spain
13h30 – 15h00
Lunch
15h00 – 15h30
Conference "Tiles of a city: Streets and monuments of Porto"
Chairperson:
Salvato Trigo, Rector of the University Fernando Pessoa
Sérgio Lira, Human and Social Sciences Faculty, University Fernando Pessoa,
Porto
15h30 – 17h00
SESSION 3 Cognition in Multiple Sclerosis
Chairpersons:
Ana Martins, Centro Hospitalar do Porto and Ana Passos, ISCTE-Instituto
Universitário de Lisboa
Assessing cognitive abilities in MS patients: Comprehensive evaluation
and brief battery approaches
Ralph H. B. Benedict, SUNNY Bufallo School of Medicine, USA
Cognitive dysfunction in MS: Problems and solutions
Maria Pia Amato, Dept. of Neurology University of Florence, Italy
17h00 – 17h30
Coffee Break | Exhibition Hall | Poster view
17h30 – 19h00
Short-courses “MS in daily clinical practice”
Organization: Pedro Abreu and Teresa Mendonça, Centro Hospitalar São João,
Porto
ROOM MEDIOTECA
ROOM BRAGA
COURSE I “Multiple Sclerosis and autoimmune diseases”
Clinical cases presentation - Paulo Alegria, Hospital Beatriz Ângelo, Loures
Interactive discussion - Pedro Abreu, Centro Hospitalar São João, Porto
Theoretical review - João Cerqueira, Hospital Escala Braga
COURSE II “Multiple Sclerosis escalating therapy”
Clinical cases presentation - Graça Sousa, Centro Hospitalar de Vila Nova de
Gaia/Espinho
Interactive discussion - Filipe Palavra, Centro Hospitalar e Universitário de
Coimbra
Theoretical review - Ernestina Santos, Centro Hospitalar do Porto
2
“SALA DE
CONFERÊNCIAS”
20h00
COURSE III “MS Team – focus in MS nurses”
Disease-modifying therapeutics in the Multiple Sclerosis Day Hospital - Fátima
Lopes, Centro Hospitalar São João, Porto
Multiple Sclerosis Disease-modifying therapeutics in the outpatient care Francisco Moreira, Centro Hospitalar Vale do Ave, Guimarães
Clinical cases presentation and discussion - Elisabete Meireles, Centro Hospitalar
São João, Porto; Odete Rodrigues, Centro Hospitalar Vale do Ave, Guimarães;
Teresa Gomes and Margarida Cardoso, Centro Hospitalar do Porto
Conference Dinner at Taylor's Port wine Lodge
SATURDAY, 26 JANUARY 2013
ALL SESSIONS | 09h00 – 16h30 | ROOM SALÃO NOBRE
9h00 – 10h30
SESSION 4 Patient-centred therapy
Chairpersons:
José Grilo Gonçalves, Centro Hospitalar Universitário de Coimbra and Rui
Pedrosa, Hospital dos Capuchos, Lisboa
Treatment “a la carte”: Reality or fiction?
Oscar Fernandez, Hospital Regional Universitario Carlos Haya, Malaga, Spain
Overview of rehabilitation approaches
Jurg Kesselring, Dept. of Neurology and Neurorehabilitation, Rehabilitation
Centre, Valens, Switzerland
10h30 – 11h00
Coffee Break | Exhibition Hall | Poster view
11h00 – 12h00
Conference “2012 Hot Topics in MS”
Chairperson:
Lívia Sousa, Centro Hospitalar Universitário de Coimbra
Otto Hommes, France
Joint Meeting with Multiple Sclerosis Study Group of Portuguese Society of Neurology
Grupo de Estudos de Esclerose Múltipla (GEEM)
12h00
Welcome address
Joaquim Pinheiro, Centro Hospitalar Vila Nova Gaia/Espinho
12h15–13h30
SESSION 5 Ten minutes vignettes of approved disease-modifying
drugs
Chairpersons:
Mário Veloso, Hospital Egas Moniz, Lisboa and Jorge Reis, Centro Hospitalar São
João, Porto
Betaferon®
Rebif®
Copaxone®
Avonex®
Tysabri®
Gylenia®
Eva-Maria Wicklein, Bayer HealthCare, Germany
Ali Ben-Amor, Merck Serono, Switzerland
Carla Fernandes,Teva Pharma, Portugal
Rossella Medori, Biogen Idec, Switzerland
Rossella Medori, Biogen Idec, Switzerland
Philipp von Rosenstiel, Novartis Pharma AG, Switzerland
3
13h30 – 14h30
Lunch
14h30 – 16h30
Oral presentations
Chairpersons:
Joaquim Pinheiro, Centro Hospitalar Vila Nova Gaia/Espinho and Joana
Guimarães, Centro Hospitalar São João, Porto
Different profiles of MMP9 activators in the CSF of MS and CIS patients
João Cerqueira, Susana Monteiro, Ana Sousa, João Torres, João Sousa,
Fernanda Marques, Joana Palha, Nuno Sousa
Results from TEMSO and TOWER: Two randomised, double-blind,
placebo-controlled phase III studies of oral teriflunomide in patients
with relapsing Multiple Sclerosis
Armando Sena, Christian Confavreux, Tomas Olsson, Giancarlo Comi, Mark
Freedman, Aaron Miller, Jerry Wolinsky, Ludwig Kappos, Hadj Benzerdjeb,
Deborah Dukovic, Philippe Truffinet, Paul O'Connor
Speech and swallowing disorders in Multiple Sclerosis
Marta Silva, Ricardo Jorge Santos
Oligoclonal bands in Multiple Sclerosis disease course
Ana Valado, Maria Helena Garrucho, João Sargento-Freitas, Sónia Batista, Lívia
Sousa, Catarina Resende Oliveira, Inês Baldeiras
A case of antiAquaporine 4 antibody positive Neuromyelitis Optica and
a successful pregnancy
Andreia Gomes Pereira, Cláudia Araújo, Ana Palha, Artur Costa e Silva, Teresa
Moreno, Maria Isabel Leite, Ruth Geraldes
Why is that important to validate neuropsychological instruments to
the clinical practice? The case of a battery of neuropsychological tests
for Multiple Sclerosis patients in Portugal
Mariana Rigueiro Neves, Ana Margarida Passos, Aristides Ferreira, Cláudia
Sousa, Maria José Sá
SIMS (Seasonality in Multiple Sclerosis): Seasonal Variation of MS
Relapse Rate
Ana Massano, Augusto Ferreira, Carlos Andrade, João Raposo, Miguel Grunho,
Sílvia César, Pedro Barros
Multiple Sclerosis and Motherhood Choice: An observational study of
the Portuguese women (EMINA study)
Ana Teresa Carvalho, Andreia Veiga, Joana Morgado, Raquel Tojal, Sofia Rocha,
Ângela Timóteo
Sexual Dysfunction in women with Multiple Sclerosis
Ivânia Alves, Filipe Correia, Paulo Coelho, Rui Loureiro, Sara França, Eva
Brandão
Pediatric Multiple Sclerosis in Portugal: An overview
Ana Sofia Correia, Luís Augusto, Joana Meireles, Joana Pinto, Ana Paula Sousa
Neuromyelitis optica in Portugal: A multicentre study
Joana Domingos, Luís Isidoro, Rita Figueiredo, Marisa Brum, Carlos Capela,
Pedro Barros
4
16h30 – 17h00
Coffee Break | Exhibition Hall | Poster view
17h00 – 18h00
Poster session | EXHIBITION HALL
Session I
Chairpersons:
Eva Antunes, University Fernando Pessoa, Porto and Clarinda Festas, University
Fernando Pessoa, Porto
0001 - What scientific evidence suggests about the effectiveness of physical
activity / physical exercise in Multiple Sclerosis?
Filipa Fonseca, Anabela Martins
0010 - The influence of home-based exercise programme on the functionality
and quality of life in patients with Multiple Sclerosis
Cláudia Silva, Joana Nunes
0023 - Multiple Sclerosis: The experience of a group therapy in rehabilitation
Daniela Pinto, Mónica Bettencourt, Melissa Gorayeb, Daniela Prada
0031 - Gait rehabilitation in Multiple Sclerosis: Rationale for robot assisted
treadmill training
Luís Boaventura, Graça Sousa, António Jorge
0040 - Effects of disability and depression in the quality of life of patients with
Multiple Sclerosis
David Costa, Maria José Sá, José Calheiros
0043 - The importance of speech therapy in Multiple Sclerosis
Maria de Fátima Xavier Ruivo
Session II
Chairpersons: Teresa Mendonça, Centro Hospitalar São João, Porto and
Ernestina Santos, Centro Hospitalar do Porto
0006 - Clinical, epidemiological, demographical and statistical data of MS
patients followed of the departments of Neurology/MS, Hospital de São Marcos,
Braga and Hospital Senhora da Oliveira, Guimarães, Portugal on 2009/12/31
José Figueiredo, Ângela Silva, João Cerqueira, Paulo Pereira
0009 - Cadasil: An alert for differential diagnosis with Multiple Sclerosis
Isabel Moreira, Ana Martins Silva, Ernestina Santos
0024 - Vesicourethral dysfunction in Multiple Sclerosis
Daniela Pinto, Anabela Ferreira, Filipa Faria, Maria da Paz Carvalho
0025 - Multiple Sclerosis and etanercept treatment: A clinical case
Silvia César, Sandra Perdigão
0033 - Prevalence, awareness and knowledge of Multiple Sclerosis in the general
population in Portugal: The EMCoDe Study
Joaquim Pinheiro, Pedro Barros, Leonor Sequeira
5
0039 - A case of hemophagocytic lymphohistiocytosis syndrome in a patient with
Multiple Sclerosis on fingolimod therapy
Pedro Abreu, Carla Peixoto, Cláudia Carvalho, Helena Gomes, Lurdes Santos,
António Sarmento, Maria José Sá
0044 - Acute myelitis: 5 year-retrospective study of a Portuguese population
Leonor Almeida, Carlos Andrade, Maria José Sá, Carolina Garrett, Joana
Guimarães
Session III
Chairpersons: João Cerqueira, Hospital de Braga, Braga and Rita Simões,
Hospital Fernando Fonseca (Amadora-Sintra), Amadora
0003 - Anti-inflammatory cytokines and the physical activity in Multiple Sclerosis
Margarida Florindo
0005 - Possible interaction between oral contraceptive use with apoe
polymorphism in disabling progression of Multiple Sclerosis
Carlos Capela, Armando Sena, Rémy Courderc, Véronique Ferret-Sena, Rafael
Roque, Ana Sousa, Joana Morgado, Rui Pedrosa
0020 - Subpopulations of monocytes and dendritic cells in Multiple Sclerosis
Andreia Monteiro, Mafalda Fonseca, Luiza Rosado, Pedro Rosado, António
Atalaia, Tiago Carvalheiro, Artur Paiva
0030 - Acute demyelinating syndrome presenting as encephalitis
Rita Simões, José Vale, Teresa Nunes, Nuno Ruivo, António Messias, José
Pimentel
0036 - Cognitive assessment in Susac’s syndrome: Two case reports
Andreia Sá, Cláudia Sousa, Joana Meireles, Pedro Abreu
0041 - Cognitive impairment in radiologically isolated syndrome
Joana Meireles, Cláudia Sousa, Pedro Abreu, Maria José Sá
0051 - The cogniplus study: Assessment of cognitive performance plus physical
activity in patients with relapsing-remitting Multiple Sclerosis
Maria José Sá, Bruno Brochet, Alexander Tallner, Eva-Maria Wicklein, Karola
Beckmann, Dawn Langdon
Session IV
Chairpersons: Jorge Reis, Centro Hospitalar São João, Porto and Maria Manuel
Campos, Centro Hospitalar São João, Porto
0008 - Mcardle’s disease and Multiple Sclerosis: A rare association
Carolina Figueira, Filipe Palavra, Amélia Guilherme, Manuel Melo Pires, José Grilo
Gonçalves
0013 - Baló’s concentric sclerosis: A clinico-radiological paradox and the
therapeutic dilemma
Daniela Jardim Pereira, Beatriz Santiago, Pureza Dias, Lívia Sousa
0016 - Multiple Sclerosis and Oligodendroglioma: A very rare association
Ana Carvalho, Paulo Linhares, Lígia Castro, Maria José Sá
0017 - Lyme Neuroborreliosis and Multiple Sclerosis: a challenging diagnosis...
Silvia César, Rosa Lobato, Sandra Perdigão
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0022 - Complex partial seizures as a presenting form of Multiple Sclerosis
Helena Felgueiras, Pedro Barros, Ana Carvalho, Miguel Veloso, Joaquim Pinheiro
0027 - Granulomatous uveitis, sensorial deafness and brain demyelination: Is it
Cogan syndrome?
Andreia Gomes Pereira, Lia Neto, Ana Casas Novas, Filipa Ramos, Cidalina
Ferreira, Ruth Geraldes
0045 - Sensorineural hearing loss: An autoimmune sign
Carlos Andrade, Miguel Bernardes, Maria José Sá, Joana Guimarães
Session V
Chairpersons: Pedro Abreu, Centro Hospitalar São João, Porto and Vasco
Salgado, Hospital Fernando Fonseca (Amadora-Sintra), Amadora
0007 - Disability improvement with Alemtuzumab vs. interferon beta-1a in
relapsing- remitting Multiple Sclerosis patients who experienced disease activity
on prior therapy (care-MS II)
Gavin Giovannoni, Douglas Arnold, Jeffrey Cohen, Alasdair Coles, Christian
Confavreux, Edward Fox, Hans Hartung, Eva Havrdova, Krzysztof Selmaj,
Howard Weiner, Cary Twyman, Tamara Miller, Stephen Lake, David Margolin,
Michael Panzara, Alastair Compston
0032 - The star study: 1-year results of an observational study to assess safety
and tolerability of, and adherence to, serum-free subcutaneous interferon beta1a in patients with relapsing-remitting Multiple Sclerosis in real-life settings
Raymond Hupperts, Ana Martins da Silva, Kurt Marhardt, Nikolaos Vlaikidis,
Hanna Kuusisto, Lizette Ghazi-Visser, Michalis Arvanitis
0037 - How and when should we perform an MRI in natalizumab treated
patients?
Helena Rocha, Maria José Sá, Pedro Abreu
0038 - Progressive multifocal leukoencephalopathy in a low-risk MS patient
treated with natalizumab
Helena Rocha, Maria José Sá, Pedro Abreu
0042 - Tysabri Observational Program (TOP): The Portuguese baseline
characteristics – an update on the efficacy and safety data
Pedro Abreu, Maria José Sá, João Sá
0048 - Early effect of fingolimod on clinical and MRI related outcomes in
relapsing Multiple Sclerosis
Davorka Tomic, Peter Chin, Peter Calabresi, Ying Zhang, Philipp von Rosenstiel,
Ludwig Kappos
0049 - Phase III freedoms study extension: Fingolimod (FTY 720) efficacy in
patients with RRMS receiving continuous or placebo-fingolimod switched therapy
for U PTO 4 years
Ernst Wilhelm Radue, Ludwig Kappos, Paul O'Connor, Chris Polman, Reinhard
Hohlfeld, Krzysztof Selmaj, Catherine Agoropoulou, Shannon Ritter, Philipp von
Rosenstiel, Lixin Zhang-Auberson
0050 - Long-term safety of fingolimod in relapsing Multiple Sclerosis: Update to
integrated analyses of phase 2 and 3 studies and extension phases
7
Tracy Reynolds, Jeffrey Cohen, Paul O'Connor, Teofilo Caliolio, Philipp von
Rosenstiel, Lixin Zhang-Auberson, Astrid Keil, William Collins, Nikolaus Sfikas,
Ludwig Kappos
Session VI
Chairpersons: Cláudia Sousa, Centro Hospitalar São João, Porto and Élia
Baeta, Unidade Local de Saúde do Alto Minho, Viana do Castelo
0011 - Diffusion tensor imaging in Multiple Sclerosis: A proxy of cognitive
efficiency?
Rosana Magalhães, Luciana Gomes, Liliana Maia, Filipe Palavra, José Grilo
Gonçalves, Óscar Gonçalves, Adriana Sampaio
0012 - Training of attention with computerized program in patients with Multiple
Sclerosis
Ana Maria Canzonieri, Kelen Cristina de Jesus, Juliana Gonçalves, Denise
Carvalho, Mara Crisitina Giacomo, Liliana Russo
0014 - Assessment of coping ability, through the color pyramid test pfister (TPC)
in patients with Multiple Sclerosis
Ana Maria Canzonieri, Kelen Cristina de Jesus, Maria Cristina Giacomo, Liliana
Russo
0015 - Transversal cut of a sample of patients with Multiple Sclerosis
Ana Maria Canzonieri, Kelen Cristina de Jesus, Maria Cristina Giacomo, Liliana
Russo
0019 - Validation of Portuguese version of the modified fatigue impact scale and
the fatigue severity scale for individuals with Multiple Sclerosis
Luciana Reis Gomes, Filipe Palavra, José Maurício Haas Bueno, Rosana
Magalhães, José Grilo Gonçalves, João Cerqueira, Óscar Filipe Gonçalves
0021 - Scale validation MSQOL54 for patients with Multiple Sclerosis
Ana Maria Canzonieri, Rute Meneses, José Pais-Ribeiro, Luisa Pedro, Isabel Silva,
Kelen Cristina de Jesus, Camyla Azevedo, Juliana Gonçalves, Maria Cristina
Giacomo, Liliana Russo
0034 - Multiple Sclerosis functional composite assessment in Portuguese MS
patients
Andreia Sá, Diana Pereira, Cláudia Sousa, Maria José Sá
20h00
Dinner at the restaurant “Casa da Música”
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