N e p h r o l o g y D e p a r t m e n t H o s p i t a l G a r c i a d e O r t a 1st International Caparica Conference in Translational Nephrology http://www.nephromics2014.com/ Sponsors: NEPHROMICS 2014 Baxter Genzyme Novartis Diaverum Fresenius Shire OM Pharma Amgen Abbvie O R G A N I Z E R S - Nephrology Service , Hospital Garcia de Orta, Portugal - Bioscope Research Group - FCT—UNL,Lisbon, Portugal 1 8 TH P ORTUGUESE S YMPOSIUM IN R E N AL D I S E AS E S : “ F ROM – OMICS TO C L I N I C AL P R AC T I C E ” 10-11 Oct 2014 COSTA CAPARICA HOTEL Day 1– Friday 10 Day 2 – Saturday 11 18th Portuguese Symposium in Renal Diseases Nephromics 2014 09h00 Opening session 09h15 AKI –biomarkers in risk assessment and predicting models Pedro Ponce - Lisboa Moderators: João P Travassos Ana Mateus New advances in peritoneal dialysis: from biomar kers to clinical practice Anabela Rodrigues– Porto Moderators: Augusta Gaspar Teixeira e Costa 10h00 10h45 coffee break 11h15 From -omics to personalized medicine in nephrology Thomas Koeck–Hannover Moderators: Rui Alves Aura Ramos Lupus Nephritis: current update – from basics to therapy Hans-Joachim Anders – Munich Moderators: Pedro Ponce Cristina Santos Lunch 12h00 12h45 14h30 15h15 16h00 Indivivualizing therapy: Do geneticists have the tools to predict which glomerulonephritis will go wrong? João Paulo Oliveira– Porto Moderators: Edgar Almeida Joaquim Calado Diabetic Nephropathy – predicting outcomes from multiple markers Michael Rudnicki–Innsbruck Moderators: Ana Paula Silva Pedro Bravo Tolerance in transplantation: Get, monitor, act Ondrej Viklicky- Prague Moderators: Carlos Oliveira Alice Santana 09h00 Opening session 09h15 - 10h00 Gert Mayer ‘The road to stratified medicine for diabetic nephropathy’ 10h00 - 10h45 Chan-Wha Kim Proteomic analysis of glomeruli from steptozotocin-induced diabetic rats and glomerular epithelial cells at hyperglycemia 10h45 - 11h30 Yamamoto Tadashi ´Application of Proteomics to Translational Nephrology´ 11h30 - 11h45 Youhe Gao Discover Urinary Biomarkers for Kidney Disease 11h45 - 12h 30 Poster Session 12h45 - 14h30 Lunch 14h30 - 14h50 Chrishan S. Samuel ‘Profiling kidney repair to identify therapeutic strategies for renal fibrosis’ 14h50 - 15h10 Lambers Heerspink Use of OMIC techniques to predict the response to renin-angiotensin-aldosterone system intervention 15h55 - 16h10 Dr.GonçaloGraça/Joana Sousa ‘Metabolomics of human biofluids as a strategy to assist diagnosis 16h10 - 16h25 Francisco J. López New Concepts for Acute Kidney Injury Diagnosis 16h25 - coffee break 16h55 - 17h10 Ivana Markovic Environment and proteome changes of kidney tubular cells: pathophysiology of Endemic nephropathy 17h10 - 17h25 Tzu-Ling Karen Tseng DNlite: A Novel Technology for Management of the Renal Complication in Diabetes 17h25 - 17h40 Mónica Roxo-Rosa Identification of Polycystin-2 and CFTR common targets – a step towards the understanding of the Autosomal Dominant Polycystic Kidney Disease 17h40 - 17h55 Axel C. Carlsson Soluble tumor necrosis factor receptor 1 (sTNFR1) is associated with glomerular filtration rate progression and incidence of chronic kidney disease in two community-based cohorts of elderly 15h10 - 15h25 Manoocher Soleimani The Causal Role of Salt Wasting and Volume Depletion in the Pathogenesis of Hypercalciuria and Kidney Stone Generation 17h55 - 18h10 Dr. Gary Gerlach Zebrafish pronephros tubulogenesis and epithelial identity maintenance are reliant on the polarity proteins Prkc iota and zeta 15h25 - 15h40 Marie PauleMingeot Deciphering the cellular pathways of aminoglycoside antibiotics nephrotoxicity, a valuable complementation for “omics” based assessment of the drug toxicity? 18h10 - 18h15 Clara G. Dias ‘The role of Nevirapine phase I metabolites in the renal function of HIV- infected patients.’ 15h40 - 15h55 Annalisa Castagna ‘G en d er a n d s u b t y p e- s p ec i f ic al t er a t i o n s of u r i n a r y m et a b ol i c p r o fil es i n p a t i en t s a f f ec t ed b y p r im a ry al d o s t er o n i sm ’ 18h15 - 18h20 Márcia de Jesus de Sá Monteiro Analysis of urinary volatile metabolomic pattern as a potential approach for the discrimination of renal cell carcinoma (RCC) patients 18h30 Ending session