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III INTERNATIONAL SYMPOSIUM OF THE RENIN ANGIOTENSIN SYSTEM
(RAS): UNDERSTANDING SYSTEMIC, INTRACELLULAR AND TISSUE RAS
III SIMPÓSIO INTERNACIONAL DO SISTEMA RENINA ANGIOTENSINA
(SRA): ENTENDENDO O SRA SISTÊMICO, INTRACELULAR E TECIDUAL
8, 9 e 10 de Agosto de 2014
ENDEREÇO (ADDRESS): Green Place Flat, Rua Dr. Diogo de Faria, 1201, Vila
Mariana,São Paulo,SP, Cep: 04037-004
Conferência: Sala Ibirapuera
Posters: Sala Trianon
INSCRIÇÃO
Email para inscrição: [email protected]
Telefone secretaria:11 59041680, 59041681 e 59041682
Valores: R$100,00 (Alunos) e R$250,00 (Professores, Pesquisadores e Profissionais)
(pagamentos na secretaria ou no local do evento)
COORDINATOR: Dulce Elena Casarini, PhD, FAHA, Department of Medicine, Discipline
of Nephrology, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Brazil.
ORGANIZING COMMITTEE (Comitê organizador):
Lisete Michelini, PhD, Departament of Physiology, ICB, USP, São Paulo, Brasil
Maria Claudia Irigoyen, MD, PhD, Laboratory of Experimental Hypertension, INCOR,
São Paulo, Brasil.
Minolfa C. Prieto, MD, PhD. Tulane University, School of Medicine, Department of
Physiology, New Orleans, LA, USA
L. Gabriel Navar, PhD. Tulane University, School of Medicine, Department of
Physiology, New Orleans, LA, USA.
SCIENTIFIC COMMITTEE (Comitê cientifico):
Mirian Aparecida Boim PhD, Unifesp, Campus Sao Paulo
Adriana K Carmona PhD, Unifesp, Campus Sao Paulo
Guiomar N. Gomes PhD, Unifesp, Campus Sao Paulo
Fernanda Colombo MD, PhD, Incor
Fernanda Klein Marcondes PhD, FOP
Vera Faha PhD, Mackenzie
Tatiana Souza Cunha PhD, Unifesp Campus Diadema
Danielle Aragão PhD Unifesp, Campus Sao Paulo
Fernanda Aparecida Ronchi PhD, Unifesp, Campus Sao Paulo
Juliana Alamada Colucci PhD, Unifesp, Campus Sao Paulo
Juliana Dinéia Perez Brandão PhD, Unifesp, Campus Sao Paulo
Danielle Yuri Arita PhD, Unifesp, Campus Sao Paulo
Ingrid Watanabe PhD, Unifesp, Campus Sao Paulo
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PROGRAM
Days: 8, 9 e 10 de agosto de 2014
Sponsors: Universidade Federal de São Paulo, Sociedade Brasileira de Hipertensão,
Fundação Oswaldo Ramos, Fapesp, CNPq.
August 8th (8h30 to 17h30)
Opening: 8h30
Chairs:
Dulce E. Casarini, PhD. Nephrology Division, Department of Medicine, Escola Paulista
de Medicina, Universidade Federal de Sao Paulo, Brazil.
L. Gabriel Navar, PhD. Department of Physiology, School of Medicine Tulane
University, New Orleans, LA, USA.
SYSTEMIC, TISSUE AND LOCAL RAS
8h35-9h00: Gabriel Navar, PhD . Tulane University, School of Medicine, Department of
Physiology, New Orleans, LA-USA.
“Activation of the tubular Renin-Angiotensin System in hypertension”
9h05-9h30: Joe Zhuo, PhD. University of Mississippi, Jackson, MS-USA.
“Current insights and new perspectives on the roles of local paracrine and intracrine
renin-angiotensin systems in the kidney”
9h35-10h00: Janos Peti-Peterdi, MD. University of South California-USA.
“A new look of the RAS in the collecting duct”
10h00-10h20: coffee break
10h30- 11h00: Kumar Rajesh, PhD. Texas A&M Health Science Center.
“Mechanism of the Renin-Angiotensin System Activation in Diabetes”
11h05-11h30: Carlos M Ferrario, MD. Professor, Physiology/Pharmacology, Wake
Forest University School of Medicine, Winston Salem, NC
“Importance of Ang II-forming Non-canonical Pathways in the Human Heart”
11h35 – 13h00 - POSTER SECTION
Lunch Break
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14h00 - 14h25: Mirian Aparecida Boim, PhD. Nephrology Division, Department of
Medicine, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Brazil
“Mesenchymal stem cells and renovascular hypertension”
14h30 – 14h55: Mark Chappel, PhD. Wake Forest University, NC-USA.
“Advanced glycation end products (AGEs) and the Angiotensin-(1-7)-Mas Axis”
15h00 – 15h25: João Bosco Pesquero, PhD. Departamento de Biofísica, Escola Paulista
de Medicina, Universidade Federal de Sao Paulo, São Paulo, SP, Brazil.
“Normotensive ob/ob mice present high blood aminopeptidase A activity that can be
regulated by body weight”
15h30 -16h00 Cooffe break
16h05 -16h30: Romer Gonzalez-Villalobos, MD., PhD. DSRD SAfety PharmacologyPhysiology Group, Pfizer, USA.
“The renal ACE/Ang II pathway and hypertension”
16h35 – 17h05: Dulce Elena Casarini, PhD. Departamento de Medicina, disciplina de
Nefrologia, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, São Paulo,
SP, Brazil.
“Increased ACE gene dosage reduces ACE2 activity in diabetic mice kidney: involvement
of ACE/ACE2 balance on the development of diabetic nephropathy”
August 9th (8h30 to 17h30)
Chairs:
Mirian Aparecida Boim, PhD (confirmed)
Nephrology Division, Department of Medicine, Escola Paulista de Medicina,
Universidade Federal de Sao Paulo, Brazil.
Minolfa C. Prieto, MD, PhD. (confirmed)
Tulane University, School of Medicine, Department of Physiology, New Orleans, LA,
USA.
MOVING FORWARD WITH PRORENIN, RENIN, AND THEIR RECEPTOR
8h35-9h00: Genevieve Nguyen, MD. INSERM, Paris, France,Europe.
“The (Pro)Renin Receptor Functions”
9h05-9h30: Helmy Siragy, Ph.D. University of Virginia. Charlottesville, NC-USA.
“Regulation of Renal (Pro)renin Receptor Expression by Low Salt Intake”
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9h35-10h00: Alexis Gonzalez, PhD. University of Valparaiso, Valparaiso-CHILE.
“Regulation of renin expression in collecting duct cells” 10h00-10h20: coffee break
10h30- 11h00: Minolfa C. Prieto, MD, PhD. Department of Physiology, School of
Medicine, Tulane University, New Orleans, LA, USA.
“Closing Remarks in Renin and Pro-renin Receptor”
11h05-11h30: Robson Santos, PhD. Departamento de Biofísica e Fisiologia
Universidade Federal de Minas Gerais
“Alamandine, new peptide of RAS
Lunch Break
Chairs:
Fernanda Klein Marcondes, PhD. Faculdade de Odontologia, Unicamp, Piracicaba, SP,
Brazil.
Dulce E. Casarini, PhD Nephrology Division, Department of Medicine, Escola Paulista
de Medicina, Universidade Federal de Sao Paulo, Brazil.
DIABETES and SRA
14h00 - 14h25: Khalid Elased, PhD. Department of Pharmacology and Toxicology,
Wright State University School of Medicine, Dayton, USA
“Rosiglitazone and Insulin Treatment Downregulate Renal ADAM17 Protein Expression
and Attenuate Urinary ACE2 Shedding in Diabetic Mice”
14h30 – 14h55: Eric Lazartigues, Associate Professor of Pharmacology, Health Sciences
Center, School of Medicine, New Orleans, LA, USA.
“Angiotensin-II mediates ACE2 Internalization and Degradation through an
Angiotensin-II type I receptor-dependent mechanism”
15h00 – 15h30: Qian Chen Yong, PhD. Texas A&M Health Science Center.
“Hydrogen sulfide inhibits the activation of the renin-angiotensin system in diabetic
heart”
15h35 – 16h00: Candice M Thomas, PhD, Texas A&M Health Science Center.
Cardiac-specific genetic inhibition of NF-κB prevents development of diabetic
cardiomyopathy
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August 10th (9h00 to 12h00)
Chairs
Fernanda Klein Marcondes, PhD. Faculdade de Odontologia, Unicamp, Piracicaba, SP,
Brazil.
Maria Claudia Irigoyen, MD, PhD. Laboratory of Experimental Hypertension, INCOR,
Sao Paulo, Brazil.
EXERCISE/ VASCULAR PATHOLOGY / STRESS and KIDNEY DISEASE
9h00 – 9h30: Carlos Eduardo Negrão, PhD. Faculdade de Educação Física,
Universidade de São Paulo, São Paulo, SP, Brazil.
“Effects of Exercise Training on Circulating and Skeletal Muscle RAS”
9h35 -10h05: Lisete Michelini, PhD. ICB, Departament of Physiology, Universidade
Estadual de Sao Paulo, São Paulo, SP, Brazil.
“Baroreceptors’ activity mediates training-induced changes on renin-angiotensin
system (RAS) expression within the paraventricular nucleus of the hypothalamus (PVN)”
10:10 – 10h35: Tomasz J. Guzik, MD, PhD. Institute of Cardiovascular and Medical
Sciences, University of Glasgow, Glasgow, United Kingdom.
“NADPH oxidase, renin angiotensin aldosterone system and vascular pathology”
10h40 – 11h10: Fernanda Klein Marcondes, PhD. Faculdade de Odontologia, Unicamp,
Piracicaba, SP, Brazil.
RAS and stress.
11h15 – 11h45: Nadja Grobe, PhD. Wright State University Boonshoft School of
Medicine, Department of Pharmacology and Toxicology, Dayton, OH, USA.
Maldi imaging of prolyl carboxypeptidase in chronic kidney disease.
11h50 End: Dulce E. Casarini, PhD Nephrology Division, Department of Medicine,
Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Brazil.