I. CURRICULUM VITAE 1) CONCISE BIOGRAPHY Name: Alexandra Maria de Oliveira dos Reis Borges. DOB: May 19th 1965. Nationality: Portuguese. - Medical school: University of Medicine Lisbon (1984-1990). - MD degree obtained in July 1990, final grade 17/20 (Good with distinction). - General residency in St Mary’s University Hospital (1991-1999). - Final examination in October 1992, final grade 85%/100% (24th national level out of 681 candidates) - ECFMG (Educational Commission for Foreign Medical Students) examination English test (20/01/1993): Apt. Basic Sciences (13/07/1993): Apt (83%) Clinical Sciences (20/01/1993): Apt (81%) - Radiology residency (1993-1996) at the Cancer Institute of Lisbon. Final examination in February 1997 with a final grade of 18,9/ 20. - Examination for “Animal Care and Use for Medical Research” in October 1996: Apt. - American Medical Association accredited Neuroradiology and Head and Neck fellowship at the University of California Los Angeles. Clinical Instructor from 1997 to 1999. - Examination of “State of California Radiology Supervisor and Operator”, August 1997: Apt. - Assistant Professor at UCLA from July 1999 to December 1999. - Return to the Cancer Institute of Lisbon as Hospital Assistant in January 2000 after contest. Final grade 19,5/20, 1st among the applicants. - Hospital Consultant at the Cancer Institute of Lisbon since 2000. - Responsible for Post-graduate education in Head and Neck Radiology at the Cancer Institute of Lisbon, since 2005. - Examination for the European Qualification in Neuroradiology in September 2009: Apt (certificate number 290 issued by the European Society of Neuroradiology). 1 - Gulbenkian and Champalimaud’s foundations Doctoral program “Advanced Medical Formation Program” (PFMA II) since October 2009. - PhD student at the “Instituto de Investigaciones Biomédicas Alberto Sols”, CSIC- Centro Superior de Investigaciones Científicas, UAM- Universidade Autonoma de Madrid, Madrid, Spain, from June 2010 to October 2012. - Hospital consultant degree obtained after contest in March 2013: Apt. - Present appointement: Hospital Consultant in the Radiology at the Instituto Portugues de Oncologia de Lisboa, Francisco Gentil. 2) SCIENTIFIC ACHIEVEMENTS - Published books as co-editor and author: 2 - Published chapters: 9 - Published articles: 33 - Conferences as invited speaker: 79 - Scientific papers presented: 38 - Scientific posters presented: 25 - Research projects as main investigator: 12 - Scholarships: 10 - Educational and Scientific committees: “Erasmus course in Magnetic Resonance Imaging”; European Congress of Radiology (ECR) and of the European Society of Head and Neck Radiology (ESHNR). Member of the Head and neck subcommittee of the ECR from 2001 to 2005. - Member of the PPC (Program Planning Committee) for the ECR 2007 and of the PPE (Program planning educational committee) for the ECR 2009. - Editorial activity: Editor for the section of Head and Neck Radiology for Radiology and EJR, European Journal of Radiology. A) SCIENTIFIC PAPERS INTERNATIONAL MEETINGS PRESENTED IN NATIONAL AND a) ln Portugal: 2 1. “Imaging the mandible”- Alexandra Borges, Fernando Torrinha Cancer Institute of Lisbon, July 1993. 2. “The choice of a medical subspeciality: Past and future of Radiology”- Alexandra Borges, Gama Afonso Portuguese Medical Board, Lisbon, December, 1993. 3. “Staging colo-rectal carcinoma: Comparative study of CT and endorectal ultrassound in 57 patients”- José Venâncio, Alexandra Borges, Alexandra Suspiro, Martins Barata, Paulo Fidalgo, Costa Mira, Armando Lacerda National Radiology Meeting CNR’ 94, O’Porto, October, 1994. 4. “Breast Lymphoma: Review of 21 cases”- Alexandra Borges, Teresa Proença e Cunha, Mário Tavares, Mª de Lurdes Orvalho National Radiology Meeting CNR’ 94, O’Porto, October, 1994. 5. “MR Imaging findings in TMJ Dysfunction”-Alexandra Borges, Fernando Torrinha National Radiology Meeting, CNR’ 94, O’Porto, October, 1994. 6. “Role of Imaging in Pediatric Oncology: Keys to diagnosis”- Teresa Proença e Cunha, Isabel Duarte, Alexandra Borges, Armando Lacerda National Radiology Meeting, CNR 94, O’Porto, October 13-15th, 1994. 7. “Ultrasound-guided FNAB of subclinical breast lesions”- Mário Tavares, Alexandra Borges, Leonor Moutinho, Mª de Lurdes Orvalho National Radiology Meeting, CNR 94, O’Porto, October 13-15th, 1994. 8. “Imaging laryngeal cancer: Clinical Impact”- Alexandra Borges Neuroradiology Meeting, St Mary’s University Hospital, March, 1995. 9. “Multiple Lytic lesions: Differential diagnosis”- Mário Tavares, Teresa Proença e Cunha, Alexandra Borges, Fernando Lage; Meeting of the Portuguese Society of Radiology and Nuclear Medicine, O’Porto, July 1st, 1995. 10. “Small bowell invagination: A clinical case”- Teresa Proença e Cunha, Mário Tavares, Alexandra Borges, Mª de Lurdes Orvalho; Advanced Course of Gastro-intestinal Imaging, Lisbon, September 23rd, 1995. 11. “Nodular Hepatomegaly”- Mário Tavares, Teresa Proença e Cunha, Alexandra Borges, José Carlos Marques; Advanced Course of Gastro-intestinal Imaging, Lisbon, September 23rd, 1995. 12. “CT and US of Primitive Liver Neoplasms”- Mário Tavares, Teresa Proença e Cunha, Alexandra Borges, Armando Lacerda; Advanced Course of Gastro-intestinal Imaging, Lisbon, September 23rd, 1995. 3 13. “Imaging of inflammatory arthritidis”- Alexandra Borges Radiology Meeting, Cancer Institute of Lisbon, April, 1996. 14. “Madelung disease with laryngeal involvement”- Alexandra Borges, Fernando Torrinha, Robert Lufkin, Elliot Abemayor National Radiology Meeting, CNR’96, Coimbra, May, 1996. 15. “Review of 64 cases of osteosarcoma: Clinical impact of imaging in the diagnosis, staging and follow-up”- Alexandra Borges, José Carlos Marques, Paula Colarinha, Mª do Rosário Vieira, Fernando Lage National Radiology Meeting, CNR’96, Coimbra, May, 1996. 16. “MRI of the Orbits: Failure of Fat-suppression artefact mimicking pathology”- Alexandra Borges, Robert Lufkin, Anthony Huang, Keyan Farhany, Anthony Arnold National Radiology Meeting, CNR’96, Coimbra, May, 1996. 17. “Pulmonarry Hypertension- Imaging findings”- Teresa Proença e Cunha, Alexandra Borges, Alexandra Araújo, Ana Nogueira, Isabel Duarte National Radiology Meeting, CNR’96, Coimbra, May, 1996. 18. “Imaging laryngeal trauma”- Alexandra Borges, Fernando Torrinha Hospital de S. Francisco Xavier, Lisbon, November, 1996. 19. “Temporal bone fractures: Clinical and prognostic implications”Alexandra Borges, Fernando Torrinha Hospital de S. Francisco Xavier, Lisbon, November, 1996. 20. “MR-guided Fine needle aspiration cytology in the head and neck: Comparative study between high- and low-field MR scanners”– Alexandra Borges, Pablo Villablanca, Robert Lufkin. National Radiology Meeting, CNR’98, Estoril, May, 1998. 21. “Congenital malformations of the inner ear: Imaging findings” – Alexandra Borges, Fernando Torrinha National Radiology Meeting, CNR’98, Estoril, May, 1998. 22. “Adenoid Cystic Carcinoma of the larynx: A rare cause of dysphonia” – Alexandra Borges, Fernando Torrinha National Radiology Meeting, CNR’98, Estoril, May, 1998. 23. “Otosclerosis: Post-operative Imaging findings”– Alexandra Borges, Fernando Torrinha National Radiology Meeting, CNR’98, Estoril, May, 1998. 24. “Chondroid tumors of the larynx: Imaging findings”- Alexandra Borges, Pablo Villablanca, Steven Wang, Joel Sercaz, Robert Lufkin. 4 National Radiology Meeting, CNR’98, Estoril, May, 1998. 25. “Imaging the facial nerve”- Alexandra Borges Neuro-Oncology Meeting, Cancer Institute of Lisbon, January, 2000. 26. “Meningeal and leptomeningeal enhancement: diagnosis”- Alexandra Borges Neuro-Oncology Meeting, Cancer Institute of Lisbon, April, 2000. Differential 27. “Diffusion weighted MR imaging: Basical principles and clinical applicability”- Alexandra Borges Neuro-Oncology Meeting, Cancer Institute of Lisbon, July, 2000. 28. “Imaging approach to central skull base pathology”- Alexandra Borges Neuro-Oncology Meeting, Cancer Institute of Lisbon, February, 2001. 29. “ Cervical lymphadenopathy: Imaging approach” – Alexandra Borges VI Jornadas temáticas da SPRMN/ I Jornadas Ibéricas de Radiologia Imagem em oncologia Auditório dos Hospitais Universitários de Coimbra, 16th-18th de November, 2009 b) Abroad: 1. “Frequency Selective Fat Suppression MR Imaging: Localized Asymmetric Failure of Fat Suppression Mimicking Orbital Disease”Alexandra Borges, Robert Lufkin, Anthony Huang, Keyan Farhany, Anthony Arnold. Annual NANOS Meeting (North American Neuro-Ophthalmology Society Meeting), Snowbird, Utah, USA, February 11-15th, 1996. 2. “MR Imaging Guided Biopsies in the Head and Neck Region: A Comparative Evaluation of Low Field Open and High Field Closed MR Systems” Alexandra Borges, Pablo Villablanca, Robert Lufkin. RSNA 97, Radiological Society of North America Annual Meeting, McCormick Place, Chicago, Illinois, November 30- December 5, 1997. 3. “Fenestration Surgery for Otosclerosis: Imaging findings of an unusual surgical procedure” Alexandra Borges, Ishyama A, Pablo Villlablanca, Robert Lufkin. ASHNR Annual Meeting, Phoenix, Arizona, USA, April 1-5, 1998. 4. “Nager’s Syndrome: CT Findings in the Head and Neck”- Alexandra Borges, Robert Lufkin, John Curran. ESHNR, European Society of Head & Neck Radiology, 11th Annual Meeting 5 Vienna, Austria, October 1-3, 1998. 5. “Role of CT in the Evaluation of Inflammatory Disease of the Sinonasal Tract: Correlation between CT Findings and Sinus Symptoms” – Alexandra Borges, Kenley Chin, Pablo Villablanca, Elliot Abbemayor, Dan Castro, Brad Jabour, Robert Lufkin. ESHNR, European Society of Head & Neck Radiology, 11th Annual Meeting Vienna, Austria, October 1-3, 1998. 6. “Imaging Diagnosis of Rhinosinusitis Detection of Minimal Disease: CT or MRI?” – Alexandra Borges, Pablo Villablanca, Robert Lufkin. ESHNR, European Society of Head & Neck Radiology, 11th Annual Meeting Vienna, Austria, October 1-3, 1998. 7. “Comparison of CT and MRI in the Imaging Diagnosis of Rhinosinusitis: Detection of Minimal Disease” – Alexandra Borges, Pablo Villablanca, Elliot Abemayor, Kenley Chin, Robert Lufkin. RSNA 98, Radiological Society of North America Annual Meeting, McCormick Place, Chicago, Illinois, November 29- December 4, 1998. 8. “Comparative Evaluation of CT versus MR in Patients Undergoing Endoscopic surgery for Inflammatory Paranasal Sinus Disease”- Pablo Villablanca, Alexandra Borges, Robert Lufkin. RSNA 98, Radiological Society of North America Annual Meeting, McCormick Place, Chicago, Illinois, Nov 29- Dec 4, 1998. 9. “MR-Guided FNB of the Retropharyngeal Space”- Alexandra Borges, Shahram Bonadyou, Elliot Abemayor, Robert Lufkin. ESHNR & EAONO Joint Meeting, ESHNR 12th Annual Meeting, joint with the European Academy of Otology and Neuro-Otology Brugge, Belgium, October 7-9, 1999. 10. “Marginal intracranial cysts in sinonasal tumors: Diagnostic accuracy for olfactory neuroblastoma” – Alexandra Borges ESHNR 2005, Oxford, UK, September 22-24th, 2005 B) ORAL PRESENTATIONS AS INVITED SPEAKER IN NATIONAL AND INTERNATIONAL MEETINGS a) In Portugal: 1. “Imaging approach to the supra-hyoid neck”- Alexandra Borges, Fernando Torrinha IInd Otolaryngology National Meeting for Residents, Lisbon, December, 1994. 2. “Imaging pancreatic disease” - Alexandra Borges 6 “Rationalization of imaging studies”, Health Center of Odivelas, Lisbon, May, 1996. 3. “Imaging approach to the head and neck”- Alexandra Borges “Rationalization of imaging studies”, Health Center of Odivelas, Lisbon, May, 1996. 4. “Imaging oral cavity cancer”- Alexandra Borges XIX Meeting of the Portuguese Society of Oral medicine and Dentistry (SPEMD’99), Estoril, October 22-23rd, 1999. 5. “Imaging oral cavity pathology”- Alexandra Borges “VI Course of laryngeal surgery”, Cancer Institute of Lisbon, November 3-5th, 1999. 6. “Helical-CT in the Head and Neck emergent applications”- Alexandra Borges Helical CT update: Portuguese Society of Radiology and Nuclear Medicine Meeting, University Hospital of Coimbra, Coimbra, November 15-16th, 1999. 7. “The infra-hyoid neck”- Alexandra Borges National Radiology Meeting CNR 2000, Póvoa do Varzim, May 10-13th, 2000. 8. “Cervical lymph nodes”- Alexandra Borges National Radiology Meeting CNR 2000, Póvoa do Varzim, May 10-13th, 2000. 9. “Role of imaging in the pre-operative maping of skull base neoplasms”- Alexandra Borges Round table (Carlos Suarez, Nuno Santiago, Marques Pinto, Domingos Coiteiro, Fernando Torrinha, Alexandra Borges) Oncologic Surgery Congress, Cancer Institute of Lisbon, November 21-24th, 2001. 10. “Role of Imaging in the assessment of the allergic patient”Alexandra Borges, Carla Saraiva IInd Allergology Meeting, Estoril, January 25th, 2002. 11. “Imaging facial neoplasms”- Fernando Torrinha, Alexandra Borges “Ist Practical Course of Cranio-facial Radiology”, Cancer Institute of Lisbon, March 21-23rd, 2002. 12. “Imaging Metastatic Neck Nodes: Where do we stand?”- Alexandra Borges Oncologic Surgery Congress, Cancer Institute of Lisbon, November 4-7th, 2003. 13. “Oral cavity and Oropharyngeal Pathology”- Alexandra Borges 7th Advanced Course of Radiology, Portuguese Medical Board, Lisbon, December, 2003. 7 14. Round table and clinical cases: Paranasal sinuses and salivary gland tumours”- Alexandra Borges Ist Iberic Course on oncologic ENT surgery”, Hotel Sana, Lisbon, October 1922, 2005. 15. “Imaging of the thyroid gland: Present and future perspectives” Alexandra Borges, IVth Course on Thyroid and Parathyroid Pathology: The State of the Art, IPOFG (Cancer Institute), Lisbon, November 23_ 24, 2005. 16. “Round Table: Imaging Head and Neck Tumours”- the Role of MRI”- Alexandra Borges 2nd Scientific Meeting of Head and Neck Oncology, March 30-31, 2006, Figueira da Foz, Portugal. 17. Lectures: “Skull base pathology” – Borges, A “Pathology of the oral cavity and oropharynx”- Borges, A Workshops: “Skull base pathology” “Pathology of the oral cavity and oropharynx” Erasmus 2008, 11-15th February, Lisbon, Portugal b) Abroad: 1. “Introduction to Head and Neck Radiology: Part I”- Alexandra Borges, Sundeeep Nayak. ASHNR, ASNR, ASPNR, ASITN & ASSR Joint Meeting San Diego, CA, USA, May 23-28th, 1999. 2. “Introduction to Head and Neck Radiology: Part II”- Alexandra Borges, Sundeeep Nayak. ASHNR, ASNR, ASPNR, ASITN & ASSR Joint Meeting San Diego, CA, USA, May 23-28th, 1999. 3. “The Salivary Glands”- Alexandra Borges Back to the basics: Radiology of the Head and Neck including normal anatomy ASHNR & ESHNR, American Society of Head and Neck Radiology and European Society of Head and Neck Radiology joint International Conference and Symposium, Marriot Wardman Park Hotel, Washington DC, USA, May 4-7th, 2000. 4. “Normal and Abnormal CT Findings after Ossicular Reconstruction”- Alexandra Borges Sixth International Conference on Cholesteatoma & Ear Surgery Cannes, France, June 29th to July 2nd, 2000. Chain 8 5. “Oral cavity and oropharynx: Pathology”- Alexandra Borges “EMRI” Erasmus Course: MRI of the head and neck, Brugge, Belgium, February 12th-16th, 2001. 6. “Inflammatory lesions of the oral cavity and oropharynx”- Alexandra Borges WORKSHOP: Inflammatory lesions of the neck “ESHNR & ESNR 2001” 14th Annual Meeting and Refresher Courses and 11th Advanced Course and XXVII Congress, Ancona, Italy, September 14-16th, 2001. 7. “Oral cavity and oropharynx: Pathology”- Alexandra Borges “EMRI” Erasmus Course: MRI of the head and neck, Institute Jules Bordet, Brussels, Belgium, February 4-8th, 2002. 8. “Central skull base lesions”- Alexandra Borges ESHNR 2002, October 3-5th, Estoril, Lisbon, Portugal. 9. “Cephaloceles”- Alexandra Borges ESHNR 2002, October 3-5th, Estoril, Lisbon, Portugal. 10. RC 508: Salivary Glands- “Normal anatomy and its variants”Alexandra Borges ECR 2003, Vienna, Austria, March 7-11th, 2003. 11. “Anterior and posterior skull base tumors”- Alexandra Borges Conference and workshop, ECNR 2003, Riga, Latvia, April 12-17th, 2003. 12. “Salivary Glands: Normal anatomy and its variants” “Anterior and Posterior skull base lesions” “Central Skull base lesions” “Cephaloceles” Alexandra Borges “JPR 2003” Jornadas Paulistas de Radiologia. S. Paulo, Brasil May 1-4, 2003. 13. “Skull base lesions” “Oral cavity and oropharynx” Alexandra Borges Conferences and Workshops “EMRI” Erasmus Course: MRI of the head and neck, A.Z. St. Jan Brugge, Brugges, Belgium, February 9-13th, 2004. 14. “RC 508”: Salivary Glands- “Choice of Imaging Technique in patients presenting with salivary gland problems”- Alexandra Borges ECR 2004, Vienna, Austria, March 4-8th, 2004. 15. “MRI of Temporomandibular Joint Dysfunction” “Anterior and posterior skull base lesions” Refresher Course 9 Alexandra Borges “ESHNR 2004”- European Society of Head and Neck Radiology Meeting”, Paris, France, October 7-9th, 2004. 16. “Nasal cavity and paranasal sinuses” “Supra and Infra-hyoid neck spaces” Alexandra Borges Conferences and workshops “ECNR 2004”- European Course in Neuroradiology, 8h cycle, 1st Course“Embryology, Anatomy, Malformations, Genetics”, October 22-26, Basel, Switzerland, 2004. 17. “Skull base lesions” “Oral cavity and oropharynx” Alexandra Borges Conferences and workshops “EMRI” Erasmus Course: MRI of the head and neck, Institute Jules Bordet, Brussels, Belgium, February 7-11th, 2005. 18. “RC 108”- Salivary Glands- “Choice of Imaging Technique in patients presenting with salivary gland problems” “CC 917”- Essentials in Neuroradiology- Three common problems: Loss of vision, hearing loss, trigeminal and facial nerve palsy. “Facial nerve paralysis and trigeminal neuralgia” Alexandra Borges “ECR 2005” European Congress of Radiology, Vienna, Austria, March 4-8th, 2005. 19. “ Anterior skull base” “Facial nerve imaging” “Salivary gland imaging” “Imaging trigeminal neuralgia” Alexandra Borges 2nd NTUH (National Taiwan University Hospital) RADIOLOGY COURSE Head and Neck Radiology, October 29-30, 2005, Taiwan. 20. “Skull base lesions” Alexandra Borges ERASMUS COURSE, EMRI Head and Neck, Vienna, Austria, February 13-17, 2006. (Conference and workshops) 21. Intervention in the head and neck: “The role of US and USgFNAC in subclinical thyroid nodules: Evidence-based guidelines”- Borges A “Anterior and central skull base tumours” – Borges A ICHNR 2006, 28th-30th September, 2006. 22. Lectures: “Skull base lesions” 10 “Oral cavity and oropharynx: Pathology” Borges A Workshops: “Skull base lesions” “Oral cavity and oropharynx” Borges A Erasmus Course 2007, MRI of the head and neck 5th-9th February, 2007, Brugges, Belgium 23. RC 908: Imaging after treatment of head and neck tumours “Imaging characteristics in denervation pathologies” – Borges A ECR 2007, 9th-13th March, 2007, Vienna, Austria 24. Lectures: “MR Imaging of the oral cavity and oropharynx”- Borges A Workshops: “MR imaging of the sinonasal tract and the skull base” “MR imaging of the nasopharynx and of the parapharyngeal space” “MR imaging of the oral cavity and oropharynx”- Borges A ESMRMB, 7th-9th June, 2007, Brescia, Italy 25. Diagnostical aspects of meningeal diseases: “Meningeal invasion by head and neck tumours” - Borges A Head and neck cancer: “Imaging changes due to denervation”- Borges A ESNNR, 6th-8th September, 2007, Oslo, Sweeden. 26. “Imaging changes due to denervation”- Borges, A ECR 2008, 7-11th March, 2008, Vienna, Austria. 27. Lectures: “MR imaging of the oral cavity and oropharynx”- Borges, A Workshops “Oral cavity and oropharynx pathology”- Borges, A “PNS and skull base pathology”- Borges, A “Nasopharynx and parphryngeal space”- Borges, A “School of MRI” of the ESMRMB, Advanced MR Imaging of the Head and Neck, 16-18th October, 2008, Prague, Check Republic 28. Lectures: “Skull base and cranial nerves anatomy”- Borges, A; Casselman, J “Meningeal invasion by head and neck tumours”- Borges, A “Imaging the salivary glands”- Borges, A “Anatomy and embryology of the paranasal sinuses”- Borges, A “Skull base pathology”- Borges, A “Imaging trigeminal neuralgia and facial nerve palsy”- Borges, A Head and neck imaging course, 5-26th October, 2008, Cape Town, South Africa 11 29. “Bone tumours of the skull base: A forgotten land”- Borges, A “Evidence based imaging in rhinosinusitis. Facts and Myths”- Borges, A ESHNR 2008, 6-9th November, 2008, Geneva, Switzerland 30. “Skull base pathology”- Borges, A Erasmus 2009, 16-20th February, 2009, Vienna, Austria 31. “Depiction of dural invasion by head and neck tumours: how good is MRI?” Borges, A; Fonseca, I. ECR 2009, 6-19th March, 2009, Vienna, Austria. 32. “How to report on… Post-RT complications”- Alexandra Borges Refresher course “Pathology of the anterior and central skull base” - Alexandra Borges ESHNR 2009 1st-3rd October, 2009. 33. “MR imaging of the oral cavity and oropharynx” – Alexandra Borges Conference and 3 hrs workshop ESMRI Alicante 6-8 October, 2009 C) SCIENTIFIC POSTER PRESENTATIONS: a) In Portugal: 1. “Role of imaging in Pediatric Oncology”- Teresa Proença e Cunha, Isabel Duarte, Alexandra Borges, Armando Lacerda; National Radiology Meeting CNR 94, O’Porto, October 13-15th, 1994. 2. “Bone Metastasis: Role of Imaging in diagnosis”- José Carlos Marques, João Gomes, Teresa Proença e Cunha, Alexandra Borges, Fernando Lage; National Radiology Meeting CNR 94, O’Porto, October 13-15th, 1994. 3. “Necrotizing lesions in the sinonasal tract: A new concept” – Alexandra Borges, James Fink, Pablo Villablanca, Robert Lufkin. National Radiology Meeting CNR’98, Bicesse, Estoril, May 20-23rd, 1998. 4. “MRI of the Orbits: Failure of fat-suppression artefact mimicking pathology” – Alexandra Borges, Jeffrey Wensel, Robert Lufkin, Anthony Wang, Anthony Arnold. National Radiology Meeting, CNR’98, Bicesse, Estoril, May 20-23rd, 1998. 5. “MRI of the inner ear of the guinea pig: An anatomic model for Choclear pathology in humans” Alexandra Borges, Jack Chen, Pablo Villablanca, James Andrews, Robert Lufkin. National Radiology Meeting, CNR’98, Bicesse, Estoril, May 20-23rd, 1998. 6. “Lesions of the sphenoidal triangle” 12 Gonçalves M, Borges A. CNR 2006, Vila Moura, Algarve, Portugal 7. “Extra-Osseous plasmocytoma in the head and neck” Pereira I, Borges A. CNR 2006, Vila Moura, Algarve, Portugal 8. “Vascular lesions in the head and neck”- Maria João Barata, Miguel Castro, Alexandra Borges CNR 2008, 14-17th May, 2008, Vilamoura, Portugal 9. “Minor salivary gland malignancies”- Miguel Castro, Maria João Barata, Alexandra Borges CNR 2008, 14-17th May, 2008, Vilamoura, Portugal 10. “Non-squamous cell laryngeal neoplasms”- Sónia Medeiros, Alexandra Borges CNR 2008, 14-17th May, 2008, Vilamoura, Portugal 11. “The bocal space revisited”- Pedro Alves, Alexandra Borges ESHNR 2008 Geneve, 6th-9th November 2008. b) Abroad: 1. “Imaging of Mandibular Lytic and Mixed Lesions”- Torrinha, F., Borges, A., Cunha, T.M., Duarte, I.; “VIIth Anual Meeting of the European Society of Head and Neck Radiology” ESHNR93, Barcelona, Spain, May 2-5th, 1993. 2. “Frequency Selective Fat Suppression MR Imaging: Localized Asymmetric Failure of Fat Suppression Mimicking Orbital Disease”Alexandra Borges, J.P. Wensel, Robert Lufkin, Anthony Huang, Anthony Arnold; ASNR’96 (American Society of Neurorradiology Annual Meeting), Washington State Convention and Trade Center, Seattle, Washington, U.S.A, June 21-27th, 1996. 3. “Staging and Follow Up in Tongue Cancer Patients: How Helpful is CT?”- Alexandra Borges, Fernando Torrinha. Advanced Course on Head and Neck Tumors: Oral Cavity and Oropharynx, European School of Oncology, Milan, Italy, November 25-27th, 1996. 4. “Necrotizing Inflammatory Lesions of the Sinonasal Tract: A New Concept” Alexandra Borges, James Fink, Pablo Villablanca, Robert Lufkin. ASHNR 32nd Annual Meeting, Phoenix, Arizona, April 1-5th, 1998. Suma Cum Laude prize 13 5. “CT Staging and Follow Up in Tongue Cancer Patients”- Alexandra Borges, Robert Lufkin, Fernando Torrinha. RSNA 98, Radiological Society of North America Annual Meeting, McCormick Place, Chicago, Illinois, November 29- December 4, 1998. 6. “Magnetic Resonance Guided Biopsy: A review”- Alexandra Borges, David LU, Nicole DeBruhl, Tateshima, S, Villablanca, JP, Williams, SI. RSNA 98, Radiological Society of North America Annual Meeting, McCormick Place, Chicago, Illinois, November 29- December 4, 1998. 7. “MRI Guided Fine Needle Aspiration of Retropharyngeal Masses”Annie Lai, Alexandra Borges, John Curran, Elliot Abemayor, Robert Lufkin. ASHNR & ESHNR, American Society of Head and Neck Radiology and European Society of Head and Neck Radiology joint International Conference and Symposium May 4-7, 2000 Marriot Wardman Park Hotel Washington DC, USA. 8. “Correlation between symptoms reported by patients with clinically suspected rhinosinusitis and sinus abnormalities determined by CT findings”- Dimitri Nyazov, Alexandra Borges, Kenley Chen, Dan Castro, Brad Jabour, Elliot Abemayor, Robert Lufkin. Prize Magnum Cum Laude. ASHNR & ESHNR, American Society of Head and Neck Radiology and European Society of Head and Neck Radiology joint International Conference and Symposium May 4-7, 2000 Marriot Wardman Park Hotel Washington DC, USA. 9. “Differentiation of the Fluid Compartments of the Cochlea in vivo Using Magnetic Resonance Imaging at 1.5T”- Dimitri Nyazov, Alexandra Borges, James Andrews, Robert Lufkin. Prize Cum Laude ASHNR & ESHNR, American Society of Head and Neck Radiology and European Society of Head and Neck Radiology joint International Conference and Symposium May 4-7, 2000 Marriot Wardman Park Hotel Washington DC, USA. 10. “Tumors and tumor-like conditions of the mandible- Pictorial review” Sofia Vinhais, Alexandra Borges, Fernando Torrinha ESHNR 2002, 3-5 Outubro, Estoril. 11. “Weird sinonasal mucoceles”- Alexandra Borges, Fernando Torrinha 14 ESHNR 2005, Oxford, UK, September 22-24th, 2005 2nd Prize Cum Laude 12. “Dural invasion by sinusal malignancies: Predictive value of MR” ESHNR 2005, Oxford, UK, September 22-24th, 2005. 13. “Dural invasion by head and neck tumours: Predictive value of MRI” ECR 2008, 7-11th March, 2008, Vienna, Austria. 13. “Marginal intracranial cysts in sinonasal tumours: Diagnostic accuracy for olfactory neuroblastomas” ECR 2008, 7-11th March, 2008, Vienna, Austria. 14. “The bocal space revisited”- Alves, P, Borges, A ESHNR 2008, 6-9th November, 2008, Geneva, Switzerland D) SESSION’S MODERATOR 1. ESHNR 2002, October 3-5th, Estoril, Lisbon, Portugal. Refresher course 3- Facial Bones. 2. ESHNR 2004, 7th-9th October, 2004, Paris, France Scientific session: The ear and temporal bone 3. ECR 2006,3rd-7th March, 2006, Vienna, Austria RC 808: How to investigate facial pain 4. ECR 2007, 9th-11th March, 2007, Vienna, Austria Scientific session: SS 1414- Old problems new solutions: CT and MR 5. ECR 2008, 7-11th March, 2008, Vienna, Austria. Scientific session: SS 208 - Diffusion and perfusion imaging in the head and neck neoplasms 6. ESHNR 2008, 6-9th November, 2008, Geneva, Switzerland Scientific session: Temporal bone E) CONTRIBUTION FOR RADIOLOGICAL QUIZES CNR 2000, Póvoa do Varzim, Portugal, May 10-13th, 2000. Neurosarcoidosis Pandred Syndrome ECR 2003, Vienna, Austria, March 7-11th, 2003. Oropharyngeal fibrovascular polyp Pigmented villonodular sinovitis of the TMJ 15 ECR 2005, Vienna, Austria, March 4-8th, 2005 Meningeal involvement by Rosai-Dorfman disease Intra-osseous pituitary adenoma ECR 2006, Vienna, Austria, March 3rd-7th, 2006 Madelung disease Pandred Syndrome F) PUBLISHED ARTICLES 1. “Imaging approach to mandibular lesions”- Alexandra Borges, Fernando Torrinha Revista Portuguesa de Otorrinolaringologia e Cirurgia Cervico-Facial, XXIII-(3): 129-144, 1995. 2. “Primary Breast Lymphoma: Review of 24 cases”- Alexandra Borges, Teresa Proença e Cunha, Mário Tavares, Mª de Lurdes Orvalho ARP, Acta Radiológica Portuguesa, IX(33): 37-43, Jan-Mar 1997. 3. “Helical CT: Emerging applications in the Head and Neck”- Alexandra Borges ARP, Acta Radiológica Portuguesa 43(11): 31-33, 1999. 4. “Infra-hyoid neck”- Alexandra Borges ARP Acta Radiológica Portuguesa, 45(12): 53-55, 2000. 5. “Cervical lymphadenopathy”- Alexandra Borges ARP Acta Radiológica Portuguesa, 45(12): 53-55, 2000. 6. “Central Skull Base Lesions”- Alexandra Borges ARP Acta Radiológica Portuguesa, 54(14): 27-29, 2002. 7. “Cephaloceles”- Alexandra Borges ARP Acta Radiológica Portuguesa, 54(14): 31-32, 2002. 8. “Frequency Selective Fat Suppression MR Imaging: Localized Asymmetric Failure of Fat Suppression Mimicking Orbital Disease”Alexandra R. Borges, Robert B. Lufkin, Anthony Huang, Keyvan Farahni, Anthony Arnold J Neuroophthalmol 17(1): 12-17, 1997. 9. “Laryngeal Involvement in Multiple Symmetric Lipomatosis: The Role of Computed Tomography in Diagnosis”- Alexandra R. Borges, Fernando Torrinha, Robert B. Lufkin, Elliot Abemayor Am J Otolaryngol 18(2): 127-130, 1997. 16 10. “MRI-guided procedures using contemporaneous imaging frameless stereotaxis in an open-configuration system”- Lee MH, Lufkin RB, Borges A, Lu DS, Sinha S, Farahani K, Villablanca P, Curran J, Hall T, Atkinson D, Kangarloo H. J Comput Assist Tomogr 22(6): 998-1005, 1998. 11. “Determining whether a parotid tumor is in the superficial or deep lobe of the parotid gland using Magnetic Resonance Imaging”- Article review- Alexandra Borges, Robert Lufkin. J Oral Maxillofac Surg, 56: 26-27, 1998. 12. “Chondroid Tumors of the Larynx: Computed Tomography Findings”- Steven Wang, Alexandra Borges, Robert Lufkin, Joel Sercaz, Marilene Wang Am J of Otolaryngol 20(6): 379-382, 1999. 13. “Giant Fibrovascular Polyp of the Oropharynx”- Alexandra Borges, Henry Bikhazi, Jeffrey Wensel. AJNNR Am J Neuroradiol 20(10):1979-1982, Nov-Dec, 1999. 14. “Midline Destructive Lesions of the Sinonasal Tract: A Simplified Terminology Based on Histopathologic Criteria” Major article Alexandra Borges, James Fink, Pablo Villablanca, Robert Lufkin. AJNR Am J Neuroradiol 21(2):278-281, 2000. 15. “MRI-guided needle localization in the head and neck using contemporaneous imaging in an open-configuration system”- Wang SJ, Sercarz JA, Lufkin RB, Borges A, Wang MB. Head Neck 22(4): 335-9, 2000. 16. “Fenestration surgery for otosclerosis: CT findings of an old surgical procedure”- Niyazov D, Borges A, Ishiyama A, Zaragoza E, Lufkin R. AJNR Am J Neuroradiol 21(9): 1670-2, 2000. 17. “MRI- guided Fine Needle Aspiration Biopsies of Retropharyngeal Lesions” Maghami EL, Bonadyou S, Larian B, Borges A, Abemayor E, Lufkin RB. Laryngoscope, 111(12): 2218-24, 2001. 18. “Adenolipoma of the thyroid gland”- Borges A, Catarino A. Radiology, 224(2),373-374, Ag, 2002. Radiology, 225(3), 746-750, Dec, 2002. 19. “MRI-guided access to the retropharynx”- Lai A, Maghami E, Borges A, Bonyadilou S, Curran J, Abemayor E, Lufkin R. J Magn Reson Imaging 17(3): 317-22, 2003. 20. “Trigeminal neuralgia and facial nerve paralysis”- Borges A. 17 Eur Radiol 15(3): 511-533, 2005. 21. “Focal thyroid incidentaloma: Evidence-based management” – Borges A. Acta Med Port 19(4): 325-33, 2006. 22. “Imaging the cranial nerves- Part I: Methodology, infectious and inflammatory, traumatic and congenital lesions” – Borges A, Casselman J. Eur Radiol 17(8): 2112-25, 2007. 23. “Imaging the cranial nerves- Part II: Primary and secondary neoplastic conditions and neurovascular conflicts” – Borges A, Casselman J. Eur Radiol 17(9): 2332-44, 2007. 24. SKULL BASE TUMOURS PART I: Imaging technique, anatomy and anterior skull base tumours Borges, A. Eur J Radiol. 2008 Jun; 66(3): 338-47. 25. SKULL BASE TUMOURS PART II: Central skull base tumours and intrinsic tumours of the bony skull base Borges, A. Eur J Radiol. 2008 Jun; 66(3): 348-62. 26. A case of advanced medullary thyroid carcinoma successfully treated with Sunitinib. Bugalho MJ, Domingues R, Borges A. The Oncologist. 2009 Nov; 14 (11): 10831087. 27.Borges A. “Imaging of the central skull base”. Neuroimag Clin N Am 19 (2009) 669–696. IF 1,54 Borges A. “Imaging cranial nerves and the brachial plexus”. Eur J Radiol. 2010 May;74(2):287. Epub 2010 Mar 12. IF 2,94 28.Borges A. “ Imaging of denervation in the head and neck”. EJR special issue on Cranial nerves imaging Eur J Radiol. 2010 May;74(2):378-90. Epub 2010 Mar 11. IF 2,94 Borges A, Casselman J. “Imaging the trigeminal nerve”.Eur J Radiol. 2010 May;74(2):323-40. Epub 2010 Mar 12. 29. Borges A, Martins M, André S.“Double thyroid ectopia with papillary thyroid carcinoma in a sublingual thyroid gland” Part I. Eur Radiol.DOI 10.1007/s00330-010-1790-y. IF 3,59 18 30. Borges A, Martins M, André S.“Double thyroid ectopia with papillary thyroid carcinoma in a sublingual thyroid gland” Part II. DOI 10.1007/s00330-0101781-z. IF 3,59 31. Casal D, Borges A, Angélica-Almeida M, Goyri-O’Neil J.“Images in rheumatology- A variant of the distal ulna in a patient with ulnar impaction syndrome”. Acta Reumatol Port 2010; 35(1): 110-1. 32. Borges A, Coiteiro D, Rosa-Santos J, Magalhães M, Fonseca I.“Using Magnetic Ressonance for the imaging of dural invasion by head and neck tumors”. Imaging in Medicine 2010, 2(5): 593-602. 33. Borges AR, Lopez-Larrubia P, Marques JB, Cerdan SG. MR imaging features of high-grade gliomas in murine models: how they compare with human disease, reflect tumor biology, and play a role in preclinical trials. AJNR Am J Neuroradiol. 2012 Jan;33(1):24-36. Epub 2011 Dec 22. IF 3,46. H) PUBLISHED BOOK CHAPTERS: 1. Practical Magnetic Resonance Imaging Editor: Frank Smith Oxford Press, 1998 “Interventional MRI” Alexandra Borges, David Lu, Pablo Villablanca, Robert Lufkin. 2. The Ear Book: A Text Book of Otology Editors: Rinaldo Canalis, Paul Lambert Lippincot-Raven, 1999. “Temporal Bone Imaging” Pablo Villablanca, Alexandra Borges, Robert Lufkin. 3. Diagnostic Testing in Otolaryngology and Head and Neck Surgery Editor: Douglas E. Mattox Igaku-Shoin Medical Publishers Inc., 1999. “Interventional CT and MRI in the Head and Neck” Alexandra Borges, Pablo Villablanca, Robert Lufkin. 4. Interventional MRI Editor: Robert Lufkin Mosby Inc., 1999 “Principles of MR-guided Ethanol Ablation” Alexandra Borges, David LU. 19 “MR-guided Biopsy in the Head and Neck” Alexandra Borges, Pablo Villablanca, Elliot Abemayor, Robert Lufkin. 5. Open Field Magnetic Resonance Imaging Equipment, Diagnosis and Interventional Procedures Editors: D. H. W. Gronemeyer and Robert B. Lufkin Springer-Verlag, 2000 “Magnetic Resonance Imaging of the Head and Neck” Alexandra Borges, P. Villablanca, Y. Anzai, J. Curran, K. Blackwell, R. Lufkin. “Interventional Magnetic Resonance Imaging in the Head and Neck” Alexandra Borges, Pablo Villablanca, Dan Castro, Elliot Abemayor, Joel Sercaz, Yoshimi Anzai, Thomas Vogl, Michael Mack, Robert Lufkin. 6. “Normal and Abnormal CT Findings after Ossicular Chain Reconstruction”- Alexandra Borges. Sixth International Conference on Cholesteatoma & Ear Surgery Proceedings Cannes, France, June 29th to July 2nd, 2000 Editors: Jacques Magnan, André Chays Copyright 2001 Label Production Ed. Marseille, France 7. “Facial nerve paralysis” Alexandra Borges ENCYCLOPEDIC REFERENCE FOR IMAGING. Editor: Prof. Albert Baert. Thieme 2009. I) CHAPTERS SEND FOR PUBLICATION: RIA project Belmedin (22 chapters) Editor: Lieven Van Hoe G) PUBLISHED BOOKS AS CO-EDITOR AND AUTHOR 1. TEACHING ATLAS OF HEAD AND NECK IMAGING Robert Lufkin, Alexandra Borges, Pablo Villablanca Thieme, 2000. 2. MRI OF THE HEAD AND NECK, 2nd edition Robert Lufkin, Alexandra Borges, Kim Nguyen, Yoshimi Anzai Lippincott Williams and Wilkins, 2001. 20 K) OTHER EDITORIAL ACTIVITY Editorial member of the European Journal of Radiology and (www.jradiology.com) - Section editor for Oncologic imaging since 2002. JRAD Reviewer for Radiology since 200 Associate Editor for Radiology, for the section Head and Neck radiology, since 2007. Occasional reviewer for European radiology. L) ORGANIZATION OF MEETINGS AND COURSES: - Member of the scientific committee and of the local organizing committee of the ESHNR 2002, October 3rd-5th, Lisbon. - Programme and module co-operator of the Eramus course module “MRI of the head and neck” from 2000 to 2008. Module organizer in 2008. - Member of the head and neck subcommittee of the ECR from 2001-2009. - Member of the faculty and scientific committee of the ECNR course in 2003 and 2004. - Member of the faculty and scientific committee of the ESMRMB from 2007 to 2009. - Member of the program planning committee, scientific committee (PPC) for the ECR 2007. Co-chairman of the Radiographers subcommittee. - Organizer of the Erasmus course of the module MRI of the head and neck held in Lisbon, February 11th to 15th, 2008. - Member of the program planning committee, educational committee (PEP) for the ECR 2009. Chairman of the Head and Neck Radiology subcommittee for the ECR 2009. - Future organizations: Erasmus Course “MRI of the head and Neck” to be held in Lisbon January 2011. 3) TITLES: - Hospital Consultant in the Cancer Institute of Lisbon 4) SCIENTIFIC SOCIETIES MEMBERSHIP 21 Portuguese Society of radiology and Nuclear Medicine Portuguese Society of Neuro-Oncology European Society of Radiology (ESR). European Society of Head and Neck Radiology (ESHNR) European School of Oncology Radiological Society of North America (RSNA) American Society of Head and Neck Radiology (ASHNR)- until 2002 American Society of Neuroradiology (ASNR) – until 2002 5) PARTICIPATION ON ONGOING CLINICAL TRIALS: 1. “RTOG 0525/ EORTC 26052-22053 An intergroup study by the Radiation Therapy Oncology Group (RTOG) and the European Organisation for the research and Treatment of cancer (EORTC) Brain Tumours and Radiotherapy Groups.” Roger Stupp Dr. Bravo Marques EORTC / RTOG 2. “20050251-SPECTRUM A phase 3 Randomized Trial of Chemotherapy with and without Panitumumab in patients with metastatic and/or recurrent squamous cell carcinoma of the head and neck” Dra Isabel Sargento AMGEN 3. “BO21990 Clinical phase 3 randomized double blind placebo controlled multicenter trial of bevacizumab, temozolamide and radiotherapy followed by bevacizumab and temozolamide Versus placebo, temozolamide and radiotherapy followed by placebo and temozolamide in patients with newly diagnosed glioblastoma.” Dr. Bravo Marques F. Hoffmann-La Roche Lda 6) CLINICAL, RESEARCH AND TEACHING INTERESTS: Clinical Interests: My main clinical interests rely on the imaging diagnosis and follow-up of Head and Neck and Central Nervous System neoplasms through the use of Ultrasound, CT, MRI, PET-CT and PET-MRI, integrated in a multidisciplinary team (Tumor Boards). I am particularly interested in the use of MR volumetry, spectroscopy, diffusion/ diffusion tensor imaging and perfusion as biomarkers of disease activity, progression and prognosis and in the early detection of complications of chemo and radiation therapies and their differential diagnosis from recurrent tumor. 22 Research Interests: My main research interests rely on the creation of diagnostic algorithms and flowcharts based on Bayesian statistical models to set the foundation for evidence based diagnosis and management of Head and Neck and CNS tumor patients; finding imaging biomarkers which predict response to treatment and prognosis non-invasively; validate the role of PWI (perfusion-weighted MRI) and BOLD imaging (blood oxygen dependent level) as biomarkers of angiogenesis in high grade gliomas and their role in predicting response to radiation and anti-angiogenic treatments (Bevacizumab); understanding the role of oral cavity microbiome in the development of post-RT complications, particularly in the development of mandibular and maxillary radiation necrosis; finding early biomarkers of perineural tumor spread in patients with squamous cell cancer of the head and neck; unravelling the mechanisms of late recurrence in patients with salivary gland malignancies; develop new MR contrast agents for molecular targeting in oncobiology. Teaching Interests: I am interested in graduate and post-graduate teaching of head and neck radiology and neuroradiology, specifically, in the field of head and neck oncology and on continuing to collaborate with the ESHNR and ESNR in providing accredited European fellowships. I am also interested in a continuing collaboration with the ESR, Erasmus and ESMRI in providing post-graduate courses to all professionals involved in the treatment, management and followup of patients with Head and Neck tumors. 23