PEDRO LOPES GRANJA CURRICULUM VITAE Born on March 11, 1970, in Porto, Portugal. CONTACT i3S -­‐ Instituto de Investigação e Inovação em Saúde (www.i3s.up.pt) and INEB -­‐ Instituto de Engenharia Biomédica (www.ineb.up.pt), University of Porto (www.up.pt) Rua do Campo Alegre, 823, 4150-­‐180 Porto, Portugal Phone: + 351 226074900 / 81 (direct); Fax: + 351 226094567 E-­‐mail: [email protected] Homepage: www.pedrogranja.net Additional information: Research gate: http://www.researchgate.net/profile/Pedro_Granja/ Scopus Author ID: http://www.scopus.com/authid/detail.url?authorId=6602391346
Researcher ID: http://www.researcherid.com/rid/B-1685-2008 ORCID: http://orcid.org/0000-­‐0003-­‐2761-­‐4929 Google Scholar: http://scholar.google.com/citations?user=iBd2bxgAAAAJ Facebook: http://www.facebook.com/pedro.l.granja LinkedIn: http://www.linkedin.com/pub/pedro-­‐granja/38/477/9b ACADEMIC QUALIFICATIONS •
PhD in Engineering Sciences. Faculty of Engineering of the University of Porto (FEUP), January 2001. •
Metallurgical Engineer. FEUP, September 1993. PRESENT POSITIONS •
Scientific Coordinator, INEB – Instituto de Engenharia Biomédica, University of Porto. •
Coordinator, Biocarrier – Biomaterials for Multistage Drug and Cell Delivery research group, at INEB. •
Deputy Coordinator, Integrated Program on Host Interaction and Response, at i3S. •
Executive Board member, INEB. •
Editor-­‐in-­‐Chief, Biomatter journal. •
Editor-­‐in-­‐Chief, Biomaterials Network (Biomat.net). •
Principal Investigator, Associate Laboratory IBMC (Institute for Molecular and Cell Biology)-­‐
INEB, University of Porto. •
Council member and Treasurer, European Society for Biomaterials (ESB). •
Member of Board of Directors, Portuguese Materials Society (SPM). •
Affiliated Professor, Instituto de Ciências Biomédicas Abel Salazar (ICBAS; Faculty of Medicine). •
Auxiliary Invited Professor, FEUP. AREA OF SCIENTIFIC ACTIVITY Pedro L. Granja n 1/41
BIOFUNCTIONAL HYDROGELS FOR TISSUE ENGINEERING Biomaterials constitute the implantable devices used to repair, replace, or support deficient or injured tissues, organs, or functions of the body. Tissue Engineering, instead, is a modern approach with the purpose of regenerating those body parts through the delivery of biomaterials, cells and molecular signals to the appropriate sites. Regenerative Medicine is a wider field, including also other strategies, such as cell delivery alone. The ideal biomaterial for most applications would be capable of mimicking all characteristics of the natural extracellular matrix (ECM). Hydrogels are materials well suited for that purpose since they share the highly hydrated state of the ECM and can be further functionalized to better mimic its function. Hydrogels can additionally be injectable, thus providing minimally invasive surgical procedures. Hydrogels of natural origin are under investigation for developing biomaterials able to mimic several key features of the ECM, such as ability to promote cell adhesion, migration, differentiation, cell-­‐driven degradation and vascularization. DOMAIN OF SPECIALIZATION The group has been specializing in directing and mechanistically following cell behavior in engineered 3D microenvironments towards the development of cell-­‐instructive injectable biomaterials for tissue regeneration, especially bone and skin. The group is focused on developing hydrogels providing an adequate environment for the entrapment and delivery of mesenchymal stem cells and/or other cell types influencing their differentiation into bone cells and/or promoting angiogenesis, such as endothelial cells and fibroblasts. Alginate-­‐based hydrogels are being functionalized with cell-­‐interactive peptides in order to reproduce some essential features of the extracellular matrix, namely cell adhesion, proteolytic degradation and guided cell differentiation. These hydrogels are also being investigated as models to study stem cells behavior and to probe cell-­‐cell and cell-­‐matrix interactions in 3D conditions in regenerative therapies and degenerative conditions (cancer). PRESENT RESEARCH INTERESTS The group’s main research interest is the biofunctionalization of hydrogels to prepare tissue engineered injectable biomaterials, capable of inducing tissue regeneration and to act as carriers of cells or cell-­‐targeted molecules. Through binding of specific cell-­‐interactive compounds, such as oligopeptides, hydrogels are designed to reproduce essential features of the extracellular matrix. An additional focus relies on Nanomedicine-­‐based strategies, namely on the functionalization of nanoparticles capable of specifically targeting cells for gene delivery and cancer diagnosis and treatment. Keywords: •
Regenerative Medicine, Tissue Engineering, Biomaterials •
Bone and skin regeneration •
Cancer •
Hydrogel functionalization •
Molecularly-­‐designed hydrogels •
Injectable materials •
Artificial extracellular matrix •
Cell immobilization/encapsulation (3D cell culture) •
Intercellular crosstalking Pedro L. Granja n 2/41
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NanoMedicine Stem cells (substrate-­‐mediated guidance of stem cells fate) COLLABORATIONS At INEB, several colleagues are involved in this activity, namely Mário A. Barbosa, Ana Paula Pêgo and Cristina C. Barrias. Current collaborators from other institutions are: IN PORTUGAL •
Raquel Soares, Centre of Pharmacology and Chemical Biopathology, Faculty of Medicine, Univ. Porto •
Raquel Seruca and Carla Oliveira, Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP) •
Paulo Bártolo, Centre for Rapid and Sustainable Product Development (CRDSP), Polytechnic Inst. of Leiria •
Helena Tomás, Madeira Chemistry Research Centre, Univ. Madeira •
João Paulo Borges, Dept. Materials Science, Univ. Nova de Lisboa •
José Gomes, Research Centre on Interfaces and Surfaces Performance, Univ. Minho ABROAD •
David J. Mooney, Laboratory for Cell and Tissue Engineering, Harvard Univ. (USA) •
Joelle Amedée, INSERM BIOTIS U.1026, Univ. Bordeaux 2 (France) •
Maria Cristina Tanzi and Paola Petrini, BioMatLab, Politecnico Di Milano (Italy) •
Lorenzo Moroni, Inst. Biomedical Technology & Technical Medicine (MIRA), Univ. Twente (The Netherlands) •
James Kirkpatrick and Ronald Unger, Inst. Pathology, Johannes Gutenberg Univ. (Germany) •
Graça Almeida-­‐Porada, Institute for Regenerative Medicine, Wake Forest Baptist Medical Center (USA) •
Beatriz Puzzi (Faculty of Medicine) and Cecília Zavaglia (Dept. Materials Engineering), Univ. Campinas (Brazil) •
Zsombor Lacza, Semmelweis Univ. (Hungary) HONORS AND AWARDS AWARDS •
2011: YSF Excellence Award, by the Young Scientists Forum of the ESB. •
2006: Jean Leray Award, by the European Society for Biomaterials (ESB). CO-­‐AUTHORSHIP OF AWARDED WORKS •
Prize for Best Poster (Ana Filipa Lourenço). Behavior of 3D cultured hMSC under basal and osteogenic conditions. 1st “Interrogations at the Biointerface: The cancer/regeneration interface” Advanced Summer School, Porto: June 20-­‐24, 2011. Lourenço AF, Gonçalves RM, Granja PL, Barrias CC, co-­‐authors. •
Prize for Best Poster (Cristina C. Barrias). Alginate hydrogels as versatile artificial microenvironments for 3d cell culture: an overview. 2nd I3S Scientific Retreat. Póvoa de Varzim: May 5-­‐6, 2011. Fonseca KB, Maia FR, Lourenço AF, Cruz FA, Granja PL, Barrias CC, co-­‐authors. Pedro L. Granja n 3/41
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Prize for Best Poster (F. Raquel Maia). Development of nanostructured 3D matrices to direct mesenchymal stem cells behaviour. 11th Edition of the "Trends in NanoTechnology” International Conference (TNT2010). Braga, Portugal: September 6-­‐10, 2010. Maia FR, Fonseca KB, Granja PL, Barrias CC, co-­‐authors. Prize for Best Oral presentation (José Luís Santos). Gene Delivery into MSCs: a Biomimetic Approach using RGD Nanoclusters based on PAMAM Dendrimers. 5th European Symposium on Biopolymers. Madeira; Portugal: November 18-­‐20, 2009. Pandita D, Santos JL, Rodrigues J, Pego AP, Granja PL, Tomás H, co-­‐authors. Prize for Best Oral presentation (Susana Guerreiro). Modulation of cells behavior when immobilized in RGD-­‐alginate. 22nd European Conference on Biomaterials. Lausanne, Switzerland: September 7-­‐11, 2009. Guerreiro S, Barbosa MA, Soares R, Granja PL, co-­‐authors. Prize Best Poster of the Day (João L. Lopes). Friction Properties of PHEMA/PMMA Hydrogels for Articular Cartilage. V International Materials Symposium -­‐ Materiais 2009 (XIV meeting of SPM -­‐ Sociedade Portuguesa de Materiais). Lisbon: April 5-­‐8, 2009. Lopes JL, Rybolova P, Granja PL, Gomes JR, co-­‐authors. Prize for Best Oral Presentation (Maritie Grellier). Cell cooperation between osteoprogenitor and endothelial cells: Its function on bone tissue engineering. ECM VIII Bone Tissue Engineering. Davos, Switzerland: June 25-­‐28, 2007. Grellier M, Bareille R, Bourget C, Ferreira Tojais N, Granja PL, Barbosa MA, Amédée J, co-­‐authors. Special Oral Presentation Award (Isabel F. Amaral). In vitro mineralisation of chitosan membranes carrying phosphate functionalities. 16th International Symposium on Ceramics in Medicine -­‐ Bioceramics 16. Porto: November 6-­‐9, 2003. Co-­‐author. •
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AWARDS FOR THE BIOMATERIALS NETWORK 2006: Selection for Current Web Contents, from the Institute of Scientific Information (ISI). 2004: First “Pearl of the Web” award, by Swissbiomat.ch. 2002: Selection for Current Web Contents, from ISI. 2001: Page of the month, by Bioquimica.online.pt. •
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FELLOWSHIPS 1994-­‐1998: PhD scholarship, from the Portuguese Foundation for Science and Technology. 1992: Industrial internship (Milan, Italy), from Programme COMETT -­‐ Biomaterials Advanced Training Project. ACADEMIC AND PROFESSIONAL EXPERIENCE •
2014-­‐present: Coordinator of the research group Biocarrier – Biomaterials for Multistage Drug and Cell Delivery, at INEB. •
2013-­‐present: Elected member of the Board of Directors of the Portuguese Materials Society (SPM). •
2012-­‐present: Scientific Coordinator of INEB. •
2012-­‐present: Affiliated Professor at ICBAS. •
2011-­‐present: Member of Executive Board of INEB. •
2010-­‐present: Editor-­‐in-­‐Chief and Founder of the journal Biomatter. •
2008-­‐present: Treasurer and Membership Secretary of ESB. •
2008-­‐present: Principal Investigator at the Associate Laboratory IBMC.INEB. •
2007-­‐present: Elected member of the Council of ESB. •
2005-­‐present: Auxiliary Invited Professor (FEUP). Pedro L. Granja n 4/41
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1998-­‐present: Founder and editor of the Biomaterials Resources on the Internet WebPage, later turned into the Biomaterials Network (www.biomat.net). Biology)-­‐INEB, University of Porto. 2012-­‐2014: Co-­‐coordinator of the NEWTherapies Group of INEB. 2011-­‐2012: Deputy Scientific Coordinator of INEB. 2009-­‐2012: Deputy Coordinator of the NEWTherapies Group, INEB. 2009 (1 month): Invited Professor at Veronique Migonney's Lab (Biomaterials and Specialty Polymers Laboratory, Institut Galillée, University Paris 13, France). 2006-­‐2013: Web Editor of the ESB. 2006-­‐2007: Deputy Coordinator of the Biointerfaces Group, INEB. 2004 (6 months): Visiting Assistant Research Scientist at Professor David Mooney's Lab (Dept. Biologic and Materials Sciences, School of Dentistry, University of Michigan, USA). 2002-­‐2008: Auxiliary Investigator at IBMC.INEB Associate Laboratory. 2002 (2 weeks): Research training at Centro di Studio per la Chimica dei Plasmi, University of Bari (Bari, Italy) and Institute of Composite and Biomedical Materials, University of Naples (Naples, Italy). 2001-­‐2002: Assistant Researcher at INEB, working on the DISC Project (Deputy Coordinator of INEB’s team and member of the Steering Committee). 1999: Founding member of the Young Scientists Forum (YSF), integrated in the 15th European Conference on Biomaterials (Bordeaux, France), sponsored by the ESB. 1998-­‐2000: Assistant researcher at INEB, working on the CARE Project. 1994-­‐2001: PhD at INEB and FEUP, supervised by Professor Mário A. Barbosa and co-­‐
supervised by Professors Charles Baquey (INSERM U.443, Institut National de la Santé et de la Recherche Médicale, Biomaterials and Tissue Repair Unit, University Bordeaux 2) and Bernard De Jéso (Institut du Pin, Dept. Vegetal Substances Chemistry, University Bordeaux 1), from France. 1989-­‐1993: Graduation in Metallurgical Engineering at DEMM, FEUP. 1992-­‐1993: Graduation thesis entitled “Production of Bioreactive Polymer/Ceramic Composites”, carried out at Dept. Metallurgical and Materials Engineering (DEMM), FEUP, and Dept. Polymer Engineering (School of Engineering, University of Minho). 1992: Training period abroad (4 months), supported by de Programme COMETT -­‐ Biomaterials Advanced Training Project, at SEIPI Spa. (Milan, Italy), a manufacturer of titanium orthopedic prosthesis. 1991-­‐1993: Member of the managing board of the Students' Association of FEUP (AEFEUP). 1990-­‐1993: Director of “Boletin Informativo”, a bulletin from AEFEUP, and collaborator of other students’ publications. 1988: Joined the university at the Polytechnic School of São Paulo University (USP), São Paulo, Brazil. Before 1988: High School studies in Porto and São Paulo, Brazil (from 1985). EDUCATIONAL ACTIVITIES RESPOSIBLE FOR CURRICULAR UNITS •
2014-­‐present: Scientific Writing Course, and Seminars. BiotechHealth -­‐ International Doctoral Program In Molecular And Cellular Biotechnology Applied To Health Sciences, ICBAS, UPorto. •
2013-­‐present: Regenerative Medicine Course. Integrated MSc Course in Bioengineering, ICBAS, UPorto. •
2008-­‐present: Tissue Repair and Regeneration Course. Integrated MSc Course in Bioengineering, FEUP and ICBAS, UPorto. Pedro L. Granja n 5/41
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2004-­‐present: Tissue Repair and Regeneration Course. PhD and MSc Program in Biomedical Engineering, FEUP, UPorto. 2007-­‐present: Biofunctional hydrogel courses. Biomaterials in Tissue Regeneration (2007-­‐
2010) and New Therapies and Technologies (2011-­‐2014) Workshops. Graduate Program in Areas of Basic and Applied Biology (GABBA), UPorto. 2004-­‐2006: Tissue Engineering Course, MSc Program in Biomedical Engineering, University of Aveiro. LECTURER IN UNDERGRADUATE AND POST-­‐GRADUATE PROGRAMS •
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2014: Publishing Science. Innovative Training Network (ITN) AngioMatTrain, Valladolid, Spain: October 22, 2014. 2014: From Biomaterials to Regenerative Medicine. Presbyterian University Mackenzie, São Paulo, SP, Brazil: April 24-­‐25, 2014. 2013: Post Graduate Program in Mechanical Engineering. São Paulo State University (UNESP), Guaratinguetá, SP, Brazil. 2013: Postgraduate Program in Materials Science and Engineering. Federal University of São Carlos (UFSCar), São Carlos, SP, Brazil. 2013: Post Graduate Program in Anatomy of Wild and Domestic Animals. University of São Paulo (USP), Brazil. 2013: Integrated MSc in Biomedical Engineering. University of Minho. 2008-­‐2011: Coordinator of Erasmus Program, Integrated MSc in Bioengineering, branch Biomedical Engineering, FEUP, UPorto. 2013: MSc Program in Biomedical Engineering, University of Minho. 2013: MSc Program in Medicine, UPorto. 2012: MSc Program in Biomaterials and Medical Devices, University of Aveiro. 2012: Cell and Tissue Engineering Advanced Course, Doctoral Program in Experimental Biology and Biomedicine (PDBEB), Centre for Neuroscience and Cell Biology (CNC), University of Coimbra. 2011: Doctoral Program on Materials Science and Engineering, University of Aveiro. 2011: Workshop on Research supporting tools, MSc in Clinical Microbiology, Faculty of Health Sciences, Fernando Pessoa University, Porto. 2011: International Doctoral School in Functional Materials (IDS-­‐FUNMAT), Lisbon. 2009-­‐2011: MIT-­‐Portugal Doctoral Programs – Nanobiotechnology and Biomaterials. European Institute of Excellence on Tissue Engineering and Regenerative Medicine, University of Minho. 2010: Doctoral Program in Pharmaceutical Sciences. Nanotechnology, Drug Delivery and Drug Targeting Course. Faculty of Pharmacy, UPorto. 2008-­‐2010: Angiogenesis Module of the Doctoral Programs in Medicine and Molecular Oncology and Metabolism: Clinics and Experimentation, Faculty of Medicine, UPorto. 2000, 2006: Advanced Courses in Cell-­‐Materials Interactions, INEB (Porto). 1998: Teaching Assistant on Materials Degradation, at DEMM, FEUP, UPorto. 1992-­‐1994: Teaching assistant in laboratory courses at DEMM, FEUP, UPorto. OTHER EDUCATIONAL INITIATIVES •
1999-­‐2006: In the framework of the YSF, co-­‐promoter of an education interest group, within the ESB, destined to create the European Doctoral Award (EDA). The first awards were attributed in September 2006. Pedro L. Granja n 6/41
COMMITTEES, BOARDS AND OTHER RELEVANT SCIENTIFIC ACTIVITIES EDITORIAL BOARDS •
Biomanufacturing Reviews (since 2015) •
Frontiers in Polymer Chemistry (since 2013) •
Biomatter, Editor-­‐in-­‐Chief (since 2010) •
Ingénierie et Recherche Biomédicale (IRBM) (2009-­‐2013) EXPERT •
European Research Council (ERC) •
Natural Sciences and Engineering Research Council of Canada (NSERC) •
European Calcified Tissue Society (ECTS) •
European Science Foundation (ESF) •
French National Research Agency (ANR) •
Innovation Agency (ADI, Agência de Inovação), Portugal •
Institute of Support to SMEs and Innovation (IAPMEI, Instituto de Apoio às Pequenas e Médias Empresas e à Inovação), Portugal •
Katholieke Universiteit Leuven (KUL), Belgium •
National University of Singapore (NUS) •
Portuguese Foundation for Science and Technology (FCT) •
Research Foundation Flanders (FWO) •
Romanian National University Research Council (CNCSIS) and the Executive Agency for Higher Education, Research, Development and Innovation Funding (UEFISCDI) REFEREE •
ACS Applied Materials & Interfaces •
Acta Biomaterialia •
Advanced Functional Materials •
Advanced Materials •
Applied Surface Science •
Biomacromolecules •
Biomaterials •
Biomedical Materials •
BioResources •
Biotechnology and Bioengineering •
Carbohydrate Polymers •
Cell Transplantation •
Composites Science and Technology •
European Polymer Journal •
Ingénierie et Recherche Biomédicale (IRBM), BioMedical Engineering and Research •
Integrative Biology •
International Journal of Biological Macromolecules •
Journal of Bioactive and Compatible Polymers •
Journal of Biomedical Materials Research (A and B) •
Journal of Dental Research •
Journal of Functional Biomaterials •
Journal of Materials Chemistry B: Materials in Biology and Medicine Pedro L. Granja n 7/41
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Journal of Materials Science: Materials in Medicine Journal of Microencapsulation Journal of the Royal Society Interface Journal of Tissue Engineering and Regenerative Medicine Macromolecular Rapid Communications Materials Research Materials Science Forum PLoS One Polymers Reactive and Functional Polymers Scientometrics Stem Cells Stem Cell Research Surface and Coatings Technology Therapeutic Delivery Tissue Engineering MEMBER OF POST-­‐GRADUATION JURYS PhD • Carlos Boto (University of Coimbra, January 2015) • Maria Moura (University of Coimbra, January 2015) • Saurabh Kapoor (University of Aveiro, December 2014) • Eva Pinho (University of Minho, Braga, July 2014) • Anne Leferink (University of Twente, Enschede, July 2014) • Ana Henriques (New University of Lisbon, Lisbon, June 2014) • Leping Yan (University of Minho, Guimarães, June 2014) • Serena Giusti (University of Pisa, Pisa, May 2014) • Nicole Lazzeri (University of Pisa, Pisa, May 2014) • Daniele Corda (University of Pisa, Pisa, May 2014) • Giovanni Baldus (University of Pisa, Pisa, May 2014) • Elena Popa (University of Minho, Guimarães, January 2014) • Sofia Caridade (University of Minho, Guimarães, December 2013) • Sezin Aday (University of Lisbon, Lisbon, December 2013) • Susana Gomes (New University of Lisbon, Lisbon, November 2013) • Liane Moura (University of Coimbra, Coimbra, November 2013) • Keila B. Fonseca (UPorto, Porto, January 2013) • Sofia Prata (New University of Lisbon, Lisbon, December 2012) • Daniela Sousa (UPorto, Porto, November 2012) • Sidónio da Cunha Freitas (UPorto, Porto, July 2012) • Susana G. Guerreiro (UPorto, Porto, February 2012) • Daniela F. Coutinho (University of Minho, Braga, December 2011) • Sílvia B. Lourenço (UPorto, Porto, November 2011) • Johan Gustavsson (Polytechnic University of Barcelona, Barcelona, July 2011) • João Maia e Silva (University of Coimbra, Coimbra, April 2011) • Bárbara Ferreira (PhD, Aveiro, January 2011) • Patrícia Coimbra (University of Coimbra, Coimbra, December 2010) • Renata Pertile (University of Minho, Braga, November 2010) Pedro L. Granja n 8/41
• Patrícia Alves (University of Coimbra, Coimbra, December 2009) • Susana Moreira (University of Minho, Braga, 2009) • José Luís Santos (University of Madeira, Madeira, September 2009) • Marta Pegueroles (Polytechnic University of Barcelona, Barcelona, September 2009) • Marta B. Evangelista (UPorto, Porto, January 2008) • Maritie Grellier (University of Bordeaux II, Bordeaux, November 2008) • Pedro Batista (Classical University of Lisbon, Lisbon, June 2008) • Eduardo Silva (UPorto, Porto, March 2008) • Céline Chollet (University of Bordeaux II, Bordeaux, October 2007) • Paula Calvinho (University of Coimbra, Coimbra, July 2007) • Sébastien Laurence (University of Bordeaux II, Bordeaux, December 2005) • Marie-­‐Christine Durrieu (HDR, University of Bordeaux II, Bordeaux, December 2005) • Laure de Taillac (University of Bordeaux II, Bordeaux, December 2004) MSc • Raquel Peixoto (University of Minho, Braga, December 2014) • Ângela Semitela (University of Aveiro, Aveiro, December 2013) • Ana Sofia Pimentel (UPorto, Porto, October 2013) • Francisco Mendonça (UPorto, Porto, October 2013) • Raquel Almeida (UPorto, Porto, October 2013) • Helena Rocha Moreira (UPorto, Porto, October 2013) • Diogo Reis Santos (UPorto, Porto, October 2013) • Ana Azevedo Moço (UPorto, Porto, July 2013) • Carla Pereira (UPorto, Porto, July 2013) • Elisabete Nunes Pires (UPorto, Porto, July 2013) • Jorge Miguel Xavier (UPorto, Porto, October 2012) • João Carlos Monteiro (UPorto, Porto, July 2012) • Carolina Reis Ferreira (UPorto, Porto, July 2012) • Gonçalo Barreto (UPorto, Porto, July 2012) • Joana Neto da Silva (UPorto, Porto, July 2012) • Lígia Pereira Bré (UPorto, Porto, July 2012) • Cláudia Ferreirinha (UPorto, Porto, March 2012) • Ana Patrícia Tojeira (Polytechnic Institute of Leiria, Leiria, December 2011) • Daniel Vasconcelos (UPorto, Porto, July 2011) • Rita Sousa (UPorto, Porto, July 2011) • Manuela Estevinho Rodrigues (UPorto, Porto, July 2011) • Ana Rita Ferreira (UPorto, Porto, July 2011) • Gisela Ferreira (UPorto, Porto, July 2011) • Inês Odila Pereira (UPorto, Porto, July 2011) • Helena Cruz (University of Minho, Guimarães, December 2010) • Cláudio Santos (New University of Lisbon, Lisbon, December 2010) • Liliana Grenho (UPorto, Porto, October 2010) • Raquel Maia (UPorto, Porto, December 2008) • Clara Extremina (UPorto, Porto, July 2006) •
OTHERS Member of Steering Committee, Emerging Technologies, University of Texas at Austin-­‐Portugal Pedro L. Granja n 9/41
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Program. Consultant for Boston MedTech Advisors (USA). Member of the technical support group (GTA, Grupo Técnico de Apoio) for the national delegates on the topic Nanosciences, Nanotechnologies, Materials and New Production Technologies (NMP) of the EU 7th Framework Programme. Representative of INEB at European Technology Platform Nanomedicine, European Commission. Representative of INEB at ERA-­‐NET "Towards an ERA in Industrial Biotechnology". European Commission. Member of the Advisory Board of the Young Scientists Forum, an initiative at the ESB. Qualified as reviewer in the “Young Scientist’s Refereeing Programme”, promoted by the journal Biomaterials (2006). PARTICIPATION IN SCIENTIFIC PROJECTS AS PROJECT LEADER •
Influence of hypergravity on the formation of blood vessels by endothelial cells (ANGIOGRAVITY). Funded by European Space Agency (ESA; Apr-­‐Sep 2014). •
Integrated program on biomedical engineering for regenerative therapies and cancer (Deputy Project Coordinator). Funded by North region Operational Program ON.2 (Jan 2013-­‐Jun 2015; 1 M€). •
Development and Biological Evaluation of Tissue Engineered Injectable Systems. Funded by Hungarian-­‐Portuguese Intergovernmental S&T Cooperation Programme (Apr 2013-­‐Apr 2015). •
Role of CD44 as a new mechanoreceptor. Funded by Programs for Academic Mobility of PhD Students, Calouste Gulbenkian Foundation (Aug 2012-­‐Jan 2013). •
Tumor-­‐targeted nanoparticles for early diagnosis of gastric cancer (TUMORTAG). Funded by FCT (May 2012-­‐May 2015; 153 k€). •
Targeting nanoprobes for early detection of invasive cancer cells using Hereditary Diffuse Gastric Cancer as a model (NANOPROBE). Funded by FCT (Sep 2007-­‐Sep 2010; 168 k€). •
Design of new gene delivery vectors based on dendrimers, alginate and the RGD sequence for bone tissue engineering (DENDRALGENE). Funded by FCT (Sep 2007-­‐Sep 2010; 175 k€). Coordinator: Helena Tomás (Univ. Madeira). Principal Investigator at INEB. •
Bridging Biomaterial Research Excellence between Industry and Academia across Europe (BRIDGE). Funded by the EC (Dec 2007-­‐Nov 2009; 1919 k€ total; 200 k€ for INEB). Coordinator: Hakan Engkvist (Univ. Uppsala, Sweden). Principal Investigator at INEB. •
Bone regeneration by stimulation of angiogenesis (ANGIO). Funded by FCT (Mar 2005-­‐Mar 2008; 95148 €). •
Microencapsulation systems for cotransplantation. Funded by Luso-­‐American Foundation (FLAD) (Jan 2004-­‐Dec 2004). AS RESEARCHER •
Bioengineering of soft tissues through placental extracellular matrices and stem cells of varied origins. Funded by National Council for Scientific and Technological Development (CNPq), Brazil (Jan 2015-­‐Dec 2017). •
Industrial Biological Biomaterials Doctorate (IB2). EID – European Industrial Doctorates, Marie Curie Initial Training Networks (ITN). Funded by the European Commission (EC) (Jan 2013-­‐Dec 2015). •
Neuro-­‐enhancement Responsible Research and Innovation (NERRI). Funded by 7th Framework Pedro L. Granja n 10/41
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Programme for Research, European Commission (Jan 2013-­‐Jan 2016). Development of a Biomaterial Microarray for High-­‐throughput Screening of 3D Cell Cultures. Funded by Portugal-­‐France Agreement: Program PESSOA (Jan 2012-­‐Dec 2014). New materials for drug/gene delivery based on the self-­‐assembly of dendrimer-­‐chitosan-­‐single stranded DNA (DENDRIMAT). Funded by FCT (Apr 2011–Apr 2014). Sr-­‐Releasing injectable system for vertebroplasty (srHYBRID). Funded by FCT (May 2010–May 2013). Extracellular matrix-­‐like multifunctional biomaterials for bone regeneration (BIOMATRIX). Funded by FCT (Feb 2010–Feb 2013). Novel biofunctional highly porous polymer scaffolds and techniques controlling angiogenesis for the regeneration and repair of the degenerated intervertebral disc (DISC REGENERATION) Funded by the EC (Feb 2008-­‐Feb 2012). Core Laboratories for the Improvement of Medical Devices in Clinical Practice from the Failure of the Explanted Prostheses Analysis (FEPA). COST Action, funded by the EC (Sep 2004-­‐Sep 2006). Novel Intervertebral Disc Prostheses (DISC). Funded by the EC (Feb 2001-­‐Jan 2005). An injectable enzyme delivery system based on apatite nanoparticles and natural hydrogel microspheres for bone regeneration. Funded by FCT (2002-­‐2005). Development de Biomatériaux Cellulosiques pour la Regénération Osseuse. Funded by the Programme de Coopération Scientifique et Technique Franco-­‐Portugais INSERM/ICCTI (2001-­‐
2002). Bioactive Biomaterials as Supports for the Immobilisation and Subsquent In Vivo Release of Imiglucerase: A New Therapeutic Approach for the Treatment of Gaucher Disease. Funded by FCT (Mar 1999-­‐Oct 2001). Tailoring of Biomaterials at the Nanoscale: Applications in Bone surgery and Heamotherapy. Funded by Bilateral Cooperation between Portugal (ICCTI) and R. P. China (Ministry of Science and Technology) (1999-­‐2001). Medical Devices for Collecting, Processing and Storing Blood and Blood Constituents (CARE). Funded by the PEDIP Programme (Portuguese Ministry of Economy) (Jan 1998-­‐Sep 2000). Biomineralization of Implant Materials (BIOMINERAL). Funded by FCT (May 1997-­‐Apr 2000). Biomatériaux et Suppléance Fonctionelle. Institut du Pin. Funded by Association Génie Biologique et Médical (GBM) Aquitaine (1995-­‐1996). AS CONSULTANT •
Mechanism of wound healing in diabetes. Funded by FCT (2012). SUPERVISION OF SCIENTIFIC WORKS POST-­‐DOCTORAL RESEARCHERS •
Tiago dos Santos. Tissue engineered 3D model of gastric wall for stomach regeneration (02/15-­‐
present). •
Faustino Wahaia. Light Scattering and Terahertz Imaging and Spectroscopy for Biomedical Applications (01/13-­‐present). •
Aureliana Filipa Sousa. Bioprinted celullarized hydrogels for in situ skin regeneration (01/13-­‐
present). •
Tiago dos Santos. Multifunctional nanoparticles for gastric cancer diagnosis (11/12-­‐12/14). •
Susana Martins. Multifunctional nanoparticles for early gastric cancer theragnosis (09/12-­‐
10/12). Currently a post-­‐doctoral researcher at the Department of Physics, Chemistry and Pedro L. Granja n 11/41
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Pharmacy (FKF), University of Southern Denmark (Odense, Denmark). Maritie Grellier. Targeting nanoprobes for early detection of invasive cancer cells using Hereditary Diffuse Gastric Cancer (HDGC) as a model. Co-­‐supervisor, IPATIMUP (01/09-­‐07/10). Currently a first grade school teacher (Bordeaux, France). Ana Catarina Oliveira. Novel injectable Hyaluronic acid/PVA system for bone regeneration (02/09-­‐11/09). Cristina Carvalho Barrias. Molecularly designed surfaces to modulate differentiation of stem cells along the osteoblastic lineage (09/05-­‐09/09). Eliana Rigo. Training on cell culture techniques for the biological characterization of biomaterials. Sabbatical (Universidade de São Francisco, São Paulo, Brazil) (05-­‐07/06). PhD STUDENTS •
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Manuela Brás. Biomechanics of new skin substitutes using Atomic Force Microscopy. Supervisor, ICBAS, UPorto (01/14-­‐present). Daniel Ferreira. A tissue engineering approach to building a stomach-­‐on-­‐a-­‐chip. Supervisor, BiotechHealth -­‐ International Doctoral Program In Molecular And Cellular Biotechnology Applied To Health Sciences, ICBAS, UPorto (01/14-­‐present). Patrick Kennedy. Innovative colorectal cancer diagnosis and treatment with engineered nanoparticles. Co-­‐supervisor, BiotechHealth -­‐ International Doctoral Program In Molecular And Cellular Biotechnology Applied To Health Sciences, ICBAS, UPorto (01/14-­‐present). Ewa Bauman. Effect of PDB on hMSCs/ECs crosstalk: towards the development of an injectable multicell delivery system produced under xeno-­‐free conditions. Co-­‐supervisor. Co-­‐supervisor, Industrial Biological Biomaterials Doctorate (IB2). EID – European Industrial Doctorates, Marie Curie Initial Training Networks (ITN). (01/13-­‐present). Ruben Brás Pereira. Device for in situ biofabrication of tissue engineered skin. Co-­‐supervisor, ICBAS (11/12-­‐present). Juliana Rosa Dias. Co-­‐Electrospinning of modified PCL nanofibers and cell-­‐laden hydrogel for skin regeneration. Co-­‐supervisor, ICBAS (11/12-­‐present). Ana Francisca Araújo. GLP-­‐1 and GLP-­‐1 analogs nanotechnology based systems for prevention and therapy of diabetes. Co-­‐supervisor, ICBAS (11/12-­‐present). Bianca do Nascimento Lourenço. Functionalized nanoparticles as screening methodology for early diagnosis of invasive gastric cancer. Supervisor, FEUP (09/12-­‐present). Sara Carvalheira Neves. 3D Hybrid Constructs for Tissue Engineering -­‐ combining functionalized hydrogels with surface-­‐structured rapid prototyped scaffolds. Supervisor, FEUP (11/11-­‐
present). João Lima Lopes. Development and tribological characterization of biomaterials for articular cartilage repair and regeneration (provisional title). Co-­‐supervisor, University of Minho (03/06-­‐
present). Cristiana Cunha. Targeting nanoprobes for early detection of invasive cancer cells using Hereditary Diffuse Gastric Cancer (HDGC) as a model. Supervisor, FMUP (09/08-­‐10/14). Abraham Rodríguez-­‐Cano. Supervision of part of PhD works, University of Extremadura, Spain (2010-­‐2014). Raquel Maia. Functionalization of a 3D gel-­‐like matrix to induce osteogenic differentiation of human mesenchymal stem cells. Co-­‐supervisor, International Iberian Nanotechnology Laboratory, INL (10/08-­‐03/14). Sandhra Carvalho. Development of chitosan/PEG/PVA injectable system containing bioactive glass nanoparticles for periodontal regeneration. Supervision of part of PhD works, Federal University of Minas Gerais, Brazil (03/2013-­‐05/2013). Keila B. Fonseca. Protease-­‐sensitive hydrogels as 3D cellular microenvironments. Supervisor, Pedro L. Granja n 12/41
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FEUP (05/07-­‐01/13). Susana G. Guerreiro. Cocultures for cell therapies in bone tissue engineering. Supervisor, FEUP (01/08-­‐02/12). Sílvia Joana Bidarra Lourenço. Enhanced bone regeneration through cotransplantation of bone cells with stimulated endothelial cells. Supervisor, FEUP (02/05-­‐11/11/11). Fabiola Munarin. Preparation and characterization of pectin microspheres loading cells as new injectable system for tissue regeneration. Supervision of part of PhD works, Politecnico di Milano, Italy (03/09-­‐07/09). José Luís Santos. Bone tissue engineering via local gene delivery. Co-­‐supervisor, University of Madeira (02/05-­‐09/09). Marta Barros Evangelista. Osteoprogenitors differentiation is regulated by cell-­‐cell and cell-­‐
extracellular matrix interactions: implications for bone tissue regeneration. Supervisor, FEUP (09/02-­‐01/08). Christiane Salgado. Matrices for bone tissue engineering. Co-­‐supervisor, UNICAMP – University of Campinas, Brazil (03/07-­‐03/08). Maritie Grellier. The cooperation between endothelial cells and osteoprogenitor cells into functional biomaterials in the study of bone repair. Supervision of part of PhD works, INSERM U.577, University Bordeaux 2 (France) (10 months, between 2006 and 2008). Céline Chollet. RGD Peptide Grafting onto PET: Impact of density and spatial distribution on cell attachment. Supervision of part of PhD works, INSERM U.577, University Bordeaux 2 (France) (05-­‐07/06). MSc STUDENTS Diana Paiva. Cellular behaviour in liquid crystalline microenvironments. Co-­‐supervisor, MSc Program in Biomedical Engineering, New University of Lisbon (09/14-­‐present). Fábio Rangel. Biofabrication of skin using self-­‐assembled cell-­‐ECM microtissues. Supervisor, MSc in Molecular and Cell Biology, FCUP (10/14-­‐present). Zanib Panni. Preparation and characterization of polygalacturonic acid hydrogels. Supervisor, MSc of Biomedical Engineering, Erasmus student from School of Engineering, University of Glasgow, Scotland (07/14-­‐12/14). Sílvia Vieira. Nanotechnology Approach for the Tracking and Control of Stem Cells Differentiation. Co-­‐supervisor, MSc Program in Biomedical Engineering, FEUP/ICBAS (11/13-­‐
10/14). João Coentro. Cellularized Artificial Model of the Gastric Mucosa. Supervisor, MSc Program in Biomedical Engineering, FEUP/ICBAS (11/13-­‐10/14). Joana Costa. Complex cell-­‐based model of intestine permeability. Supervisor, MSc Program in Biomedical Engineering, FEUP/ICBAS (11/13-­‐10/14). Carla Pereira. Development and characterization of three-­‐dimensional intestinal model for studying intestinal nanoparticle absorption. Co-­‐supervisor, MSc Program in Biomedical Engineering, FEUP (10/12-­‐present). Ângela Semitela. The synthetic activity of osteoblasts in contact with bioglasses. Co-­‐supervisor, MSc Program in Materials and Biomedical devices, University of Aveiro (05/13-­‐12/13). Raquel Costa e Almeida. Angiogenic potential of co-­‐cultures of endothelial progenitor cells with fibroblasts. Co-­‐supervisor, Faculty of Medicine of the UPorto (12/11-­‐12/13). Helena Moreira. Pectin-­‐based gels for dermo-­‐epidermal substitutes. Supervisor, MSc Program in Biomedical Engineering, FEUP (10/12-­‐10/13). Alessio Trussardi. Pectin-­‐based nanoparticles for cancer therapy. Supervisor, ERASMUS Exchange Program, from Politecnico di Milano, Italy (09/12-­‐02/13). Mónika Szepes. Preparation and characterization of hydrogels and evaluation of their Pedro L. Granja n 13/41
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biological behavior. Supervisor, ERASMUS Exchange Program, from Budapest University of Technology and Economics, Hungary (02/12-­‐09-­‐12). Jorge Miguel Xavier. Study and Development of a Model for Mimicking the Gastric Mucosa. Supervisor, MSc Program in Biomedical Engineering, FEUP (10/11-­‐09/12). Daniel Vasconcelos. Influence of the protein environment in the bacterial response to titanium alloys for medical applications. Supervisor, FEUP (02/11-­‐07/11). Cláudio Santos. Development of new biomaterials based on liquid crystalline phases of cellulose derivatives. Co-­‐supervisor, New University of Lisbon (02-­‐10/12/10). Clara I. Extremina. Influence of Antimicrobial Agents on the Adhesion of Staphylococcus epidermidis to Biomaterials. Supervisor, FEUP (05/04-­‐07/06). RESEARCH TRAINING •
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Laetitia Cinsa. Processing and histological analysis of cell-­‐laden alginate-­‐hydrogel implants. International Exchange Programme from the University of Juíz de Fora, Brazil, (11/13-­‐02/14). Vitor Caso Moreira. Preparation and characterization of pectin nanoparticles. International Exchange Programme from the University of São Paulo (USP), Brazil, (10/11-­‐03/12). Ana Leitão Ferreira. Chitosan nanoparticles for early diagnosis of gastric cancer. INEB (03/11-­‐
07/11). Cristiana Cunha. Targeting nanoprobes for early detection of invasive cancer cells using Hereditary Diffuse Gastric Cancer (HDGC) as a model. Co-­‐supervisor, IPATIMUP (02/07-­‐09/08). Grace Wu. Effect of Fibroblasts on Endothelial Cell Behaviour. IAESTE Traineeship, University of California – Berkeley, Department of Bioengineering (09/08-­‐11/08). Susana Guerreiro. Encapsulation of endothelial cells (12/06-­‐01/08). Sofia Rodrigues. Interface improvement of PET fibers/matrix. DISC Project (02/01-­‐04/05). Bruno Gomes da Silva. Determination of regenerated cellulose hydrogels crystallinity by different physical methods. Dept. Biology, Faculty of Sciences, University of Porto (04/02-­‐
12/03). Catarina Homem. Encapsulation of hepatocytes in alginate microspheres. Lab Rotation, Gulbenkian Doctorate in Biomedicine Programme (05-­‐07/03). Ana Isabel N. Silva. Development and characterization of natural materials for biomedical applications. Co-­‐supervisor, Graduation Project, New University of Lisbon (01-­‐07/03). Laure B. de Taillac. Preparation and characterization of macroporous cellulosic biomaterials. PhD works, INSERM U.443, University Bordeaux 2 (France) (06-­‐12/02). Marta B. Evangelista. Programme Ciência Viva, from MCT (07/02-­‐09/02). Eduardo A. Silva. Preparation and Characterization of Cellulose Phosphate/Calcium Phosphate Composites. Co-­‐supervisor, FEUP (05/01-­‐09/01). Cristina C. Barrias. Cellulose Phosphates as a Support for Enzyme Immobilisation. Co-­‐
supervisor, FEUP (01/98-­‐07/98). Ana Leite Oliveira. Effect of surface modifications on the mineralisation ability of polymers for bone substitution. Co-­‐supervisor, FEUP (07/97-­‐02/98). Isabel Pamplona. Degradation and mineralisation of corn starch-­‐based polymers. Co-­‐
supervisor, FEUP (04/97-­‐07/97). Vincent Darcos. Physico-­‐chemical characterisation of cellulose derivatives. Co-­‐supervisor, Maitrîse de Chimie, Institut du Pin, University Bordeaux 1 (04/96-­‐07/96). Christelle Faveau. Cellulose Phosphorylation. Co-­‐supervisor, Stage d’I.U.T, Institut du Pin, University Bordeaux 1 (02/96-­‐04/96). ORGANIZATION OF SCIENTIFIC EVENTS Pedro L. Granja n 14/41
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CHAIRPERSON Workshop Bibliometric Analysis of Research Performance. Porto (08/05/12). Functionalized Biomaterials for Organ Replacement and Regeneration – ESB Symposium (Co-­‐
Chair). XXXVIII Congress of the European Society for Artificial Organs (ESAO 2011) and IV Biennial Congress of the International Federation on Artificial Organs (IFAO 2011). Porto (9-­‐
12/10/11). Workshop Cross-­‐Disciplinary Bibliometric Analysis of Research Performance. Porto (28/04/11). Bridge Summer Course on Biomaterials and Regenerative Medicine. Funchal, Madeira (21-­‐
25/09/09). 20 years of Biomagical Engineering in Porto (co-­‐Chair). Porto (26-­‐27/06/09). Strategies/Approaches for the Regeneration of Connective Tissues – ESB Symposium (Co-­‐
Chair). Tissue Engineering and Regenerative Medicine International Society (TERMIS)-­‐EU 2008 Annual Meeting. Porto (22-­‐26/06/08) Workshop Biology in Regenerative Medicine, integrated in the X National Meeting of Biology Students. IBMC-­‐INEB, Porto (08/04/06). Young Scientists Forum at BioÉvora 2004 – II Iberian Congress on Biomaterials. Évora (09–
11/09/04). 4th Advanced Course in Cell-­‐Material Interactions (co-­‐Chair). Porto (28/06 – 04/07/03). ORGANIZING COMMITTEE •
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Bioimaging 2012 – International Symposium in Applied Bioimaging: Bridging development and Application. Porto (20-­‐21/09/12). 3rd I3S Scientific Retreat. Póvoa de Varzim (5-­‐6/05/2012). 7th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies. Porto (26-­‐27/04/2012). 10th Advanced Summer Course in Cell-­‐Materials Interactions – Self-­‐Assembly: From Nature to Clinics. Porto (22-­‐26/06/09). 2nd Workshop on Biotribology. Guimarães (25-­‐27/05/09). 9th Advanced Summer Course in Cell-­‐Materials Interactions – Bioinspired Matrices for Tissue Regeneration. Porto (16-­‐20/06/08). I3S Workshops Series, between IBMC, INEB and IPATIMUP. Porto (12/07-­‐present). 8th Advanced Course in Cell-­‐Material Interactions – Inflammation in Tissue Repair and Regeneration. Porto (18–22/06/07). 7th Advanced Course in Cell-­‐Material Interactions – Regenerative Medicine. Porto (19–
23/06/06). 4th Young Scientists Forum (YSF), integrated in the 19th European Conference on Biomaterials. Sorrento, Italy (11-­‐15/09/05). 6th Advanced Course in Cell-­‐Material Interactions. Porto (20–24/06/05). BioÉvora 2004 – II Iberian Congress on Biomaterials. Évora (09–11/09/04). 5th Advanced Course in Cell-­‐Material Interactions. Porto (05–09/07/04). YSF, integrated in the 7th World Biomaterials Congress. Sydney, Australia (17-­‐21/05/04). 3rd YSF, integrated in the 18th European Conference on Biomaterials. Stuttgart, Germany (1-­‐
4/10/03). Biocities 2002. Lisbon (28-­‐29/11/02). 2nd YSF, integrated in the 17th European Conference on Biomaterials. Barcelona, Spain (11-­‐
14/09/02). 3rd Advanced Course in Biomaterials. Porto (1-­‐5/07/02). Advanced Courses in Biomaterials. Porto (12-­‐20/06/01). Pedro L. Granja n 15/41
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1st YSF, integrated in the 15th European Conference on Biomaterials. Bordeaux, France (8-­‐
12/09/99). 12th European Conference on Biomaterials. Porto (10-­‐13/09/95). Executive Committee. Establishing a Materials Science Education Network. Porto (20/04/95). SCIENTIFIC COMMITTEE •
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26th European Conference on Biomaterials. Liverpool, UK (31/08-­‐03/09/14). 25th European Conference on Biomaterials. Madrid, Spain (8-­‐12/09/13). 4th China-­‐Europe Symposium on Biomaterials in Regenerative Medicine. Sorrento, Italy (1-­‐
4/07/2014). 3rd International Conference on Tissue Engineering. Leiria (6-­‐8/06/2013). International Conference of the European Chitin Society (EUCHIS 2013). Porto (5-­‐8/05/2013). 24th European Conference on Biomaterials. Dublin, Ireland (4-­‐9/09/11). 23th European Conference on Biomaterials. Tampere, Finland (11-­‐15/09/10). 6th Annual International Meeting of the Portuguese Society for Stem Cells and Cell Therapies. Cantanhede (28-­‐29/04/2011). VI International Materials Symposium Materiais 2011 – XV Meeting of the Portuguese Materials Society (SPM). Guimarães (10-­‐20/04/2011). 6th Latin American Congress of Artificial Organs and Biomaterials (COLAOB). Rio Grande do Sul, Brazil (17-­‐20/08/10). 2nd China-­‐Europe Symposium on Biomaterials in Regenerative Medicine. Barcelona, Spain (17-­‐
20/11/09). 22nd European Conference on Biomaterials. Lausanne, Switzerland (7-­‐11/09/09). 3rd edition of the Iberian Biomaterials Congress and the XXXI Symposium of the Sociedad Ibérica de Biomecánica y Biomateriales. Barcelona, Spain (17-­‐19/09/08). INITIATIVES FOR ENHANCING PUBLIC AWARENESS OF SCIENCE PROJECTS •
Netimplants.com -­‐ The gateway to materials in medicine. Funded by Ciência Viva -­‐ National Agency for Scientific and Technological Culture (Jun 2007-­‐Jun 2008). •
Participation in the Science Mentoring project (www.mentoring.forum.pt). Forum Estudante magazine (2007). •
Impact of multimedia content in the public perception about the utilization of biomaterials and implants. Funded by University of Porto (2006). •
Biomaterials Network (Biomat.net), the most influent website in the fields of Biomaterials and Tissue Engineering worldwide. Funded by INEB (1998). WEBSITES •
Biomedical Implants (Biomedicalimplants.com). •
Biomaterials Network (Biomat.net). EVENTS •
Exhibition “Percursos – Ciência/Arte, Admiração Ferramental e Manipulação Pessoas e Habitats”, by José Manuel Fernandes, Galeria do Palácio, Porto (15/08/2006). Collaborator. •
“Tertúlia” Research on Biology in Porto. X National Meeting of Biology Students. Café Guarany, Pedro L. Granja n 16/41
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Porto (06/04/2006). Participant. Biomedical engineering goes to school (INEB). Lectures for high school students (03/2005). Participant. Exhibition "IBMC/INEB", integrated in the 6th Forum "Ciência Viva", Pavilhão Atlântico -­‐ Parque das Nações, Lisbon (10-­‐11/05/2002). Co-­‐organizer. Exhibition "IBMC/INEB", integrated in the Science Fair, Exponor, Porto (7-­‐14/11/2001). Chairperson. Exhibition "Interaction with Science", integrated in the Science Map, Porto 2001 -­‐ European Capital of Culture, Porto (May -­‐ Nov 2001). Chairperson. Exhibition "How Engineering Cares for our Health", integrated in the Science and Technology Week, Porto (Sep 2000). Chairperson. Exhibition about Biomedical Engineering, integrated in the event Arritmia, Porto (Jun 2000). Organizing Committee. Exhibition "Materials and the Human Body: a Stroll Between Prosthesis and Implants", integrated in the 12th European Conference on Biomaterials, Porto (10-­‐13/09/1995). Chairperson. PUBLIC DEBATES AND LECTURES •
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Several lectures for undergraduate and graduate students and for the general public (see communications). Participation in TV shows, newspapers and magazines (further details at www.pedrogranja.net). ADDITIONAL ADVANCED TRAINING •
Springer Author Workshop. University of Porto. Porto (16/04/2012). •
INSERM European Meeting CIC-­‐IT (Clinical Investigation Centres for Innovative Technology) Network. Paris, France (21-­‐22/10/2010). •
European Technology Platform Nanomedicine General Assembly and Forum 2010. Milan, Italy (14-­‐15/10/2010). •
Nanomedicine -­‐ Bridging from the bench to the bedside. Barcelona, Spain (16/11/2009). •
BRIDGE-­‐SIROT Symposium -­‐ Recent Innovations in Bone and Joint Regeneration. Budapest, Hungary (07/02/2009). •
Working Group 3 -­‐ Orthopaedics Training School. Core Laboratories for the Improvement of Medical Devices In Clinical Practice from the Failure of the Explanted Prostheses Analysis (FEPA)-­‐COST 537 Project. Porto (05-­‐07/06/08). •
DMA User’s Meeting. Leiria (23/10/2007). •
Workshop to prepare the 1st Transnational Call of the ERA-­‐NET "Towards an ERA in Industrial Biotechnology". Brussels, Belgium (19/10/07). •
Biology in Regenerative Medicine Workshop. Porto (08/04/06) •
European Technology Platform Nanomedicine. Erlangen, Germany (21/03/06). •
Getting Ready for Framework 7. Porto (01/03/2006). •
Nanosciences and Nanotechnologies at the University of Porto: Challenges and Future Needs, Porto (18-­‐19/11/04). •
Training in Rodent Survival Surgery Course. University of Michigan, Ann Arbor, USA (17/06/04). •
Tissue Engineering and Regeneration Symposium. University of Michigan, Ann Arbor, USA (11-­‐
12/05/04). •
Biomedical Engineering Department Symposium – Celebrating 40 Years of Bioengineering at the UofM. University of Michigan, Ann Arbor, USA (1-­‐2/04/04). Pedro L. Granja n 17/41
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Biomaterials: Development and Applications, Coimbra (12,13,19,20/04/02). International Workshop on Functional Supramolecular System, Hang Zhou, China (28-­‐
29/10/01). NATO/ASI on Polymer Based Systems on Tissue Engineering, Replacement and Regeneration, Alvor (15-­‐25/10/01). Biocities 2001, Hamburg, Germany (11-­‐12/10/01). New Measurement Techniques for Surface Chemistry, Porto (14/12/99). Future Trends in the Collection, Processing and Storage of Blood, Viana do Castelo (26-­‐
27/11/99). Biomatériaux et Suppleance Fonctionelle (Association Génie Biologique et Médical Aquitaine), Bordeaux, France (4/11/98). Gaucher Disease: From Diagnosis to Treatment, Porto (29/05/98). Biomaterials -­‐ Molecular Tools in Bioengineering, Porto (4-­‐6/05/98). Gordon Research Conference on Biodegradable Polymers, Barga, Italy (4-­‐9/05/97). Biomatériaux et Suppleance Fonctionelle (Association Génie Biologique et Médical Aquitaine), Bordeaux, France (18/12/96). Bone Morphogenetic Proteins and Bone Reconstruction, Bordeaux, France (15-­‐16/06/95). NATO/ASI on Physics of biomaterials: Fluctuations, selfassembly and evolution, Geilo, Norway (27/03-­‐06/04/95). MEMBERSHIP TO SOCIETIES •
European Society for Biomaterials (ESB). •
Portuguese Materials Society (SPM), Polymers and Renewable Resource Materials Groups. •
Portuguese Society for Stem Cells and Cell Therapies (SPCE-­‐TC). •
Society for Biomaterials (SFB), USA. •
Tissue Engineering and Regenerative Medicine International Society (TERMIS). AUTHORSHIP OF WEBSITES •
2010-­‐present: BiomedicalImplants.com. Website about implants for the general public. •
1998-­‐present: Biomaterials Network (Biomat.net) (www.biomat.net). Editor-­‐in-­‐chief and Founder. World leading web resource in biomaterials and tissue engineering. •
2006-­‐2012: Web Editor of the European Society for Biomaterials (ESB) (www.esbiomaterials.org). •
2001-­‐present: INEB -­‐ Instituto de Engenharia Biomédica (www.ineb.up.pt). Regular collaborator. •
2002-­‐2004: IBMC – Institute for Molecular and Cell Biology (www.ibmc.up.pt). •
2000: Slavi – Welding Technology (www.slavi.com.pt). •
1998-­‐2000: Cellulose Resources on the Internet WebPage (www.biomat.net/cellulose). LANGUAGES •
English and French: Advanced •
Italian and Spanish: Average ADVISORS •
Mário A. Barbosa, INEB and University of Porto (Portugal) •
David. J. Mooney, Harvard University (USA) Pedro L. Granja n 18/41
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Charles Baquey, University OF Bordeaux, currently retired (France) PUBLICATIONS PAPERS IN INTERNATIONAL REFEREED JOURNALS 1. Kapoor S, Semitela A, Goel A, Xiang Y, Du J, Lourenço AH, Sousa DM, Granja PL, Ferreira JMF. Understanding the composition-­‐structure-­‐bioactivity relationships in diopside (CaO•MgO•2SiO2) − tricalcium phosphate (3CaO•P2O5) glass system. Acta Biomater 2015 (In Press). 2. Neves SC, Gomes DB, Sousa A, Bidarra SJ, Petrini P, Moroni L, Barrias CC, Granja PL. Biofunctionalized pectin hydrogels as 3D cellular microenvironments. J Mater Chem B 2015 (In Press). (IF 6.626) 3. Costa-­‐Almeida R, Gomez-­‐Lazaro M, Ramalho C, Granja PL, Soares R, Guerreiro SG. Fibroblast-­‐
endothelial partners for vascularization strategies in tissue engineering. Tissue Eng A 2014 (In Press). (IF 4.254) 4. Wahaia F, Kasalynas I, Siliuta D, Molis G, Urbanovic A, Silva CDC, Carneiro F, Valusis G, Granja PL. Terahertz spectroscopy for the study of paraffin-­‐embedded gastric cancer samples. J Mol Struct 2015;1079:391-­‐5. (IF 1.599) PDF 5. Wahaia F, Kasalynas I, Siliuta D, Molis G, Urbanovic A, Silva CDC, Carneiro F, Valusis G, Granja PL. Study of paraffin-­‐embedded colon cancer tissue using terahertz spectroscopy. J Mol Struct 2015;1079:448-­‐53. (IF 1.599) PDF 6. Araújo F, Shrestha N, Granja PL, Hirvonen J, Santos HA, Sarmento B. Safety and toxicity concerns of orally delivered nanoparticles as drug carriers. Expert Opin Drug Metab Toxicol 2014 (In Press). (IF 2.934) 7. Fonseca KB, Granja PL, Barrias CC. Engineering proteolytically-­‐degradable artificial extracellular matrices. Prog Polym Sci 2014;39:2010-­‐29. (IF 26.854) PDF 8. Araújo F, Shrestha N, Granja PL, Hirvonen J, Santos HA, Sarmento B. Antihyperglycemic potential of incretins orally delivered via nano and microsystems and subsequent glucoregulatory effects. Curr Pharm Biotechnol 2014;15:609-­‐19. (IF 2.511) PDF 9. Pereira C, Araújo F, Granja PL, Santos HA, Sarmento B. Targeting membrane transporters and receptors as a mean to optimize orally delivered biotechnological based drugs through nanoparticle delivery systems. Curr Pharm Biotechnol 2014;15:650-­‐8. (IF 2.511) PDF 10. Vasconcelos D, Thomas D, Granja PL, Hélary G, Migonney V. Role of protein environment and bioactive polymer grafting in the S. epidermidis response to titanium alloy for biomedical applications. Mat Sci Eng C 2014;45:176-­‐183. (IF 2.736) PDF 11. Araújo F, Shrestha N, Shahbazi M-­‐A, Fonte P, Mäkilä E, Salonen J, Hirvonen J, Granja PL, Santos HA, Sarmento B. The impact of nanoparticles on the mucosal translocation and transport of GLP-­‐1 across the intestinal epithelium. Biomaterials 2014;35:9199-­‐207. (IF 8.312) PDF 12. Branco da Cunha C, Klumpers DD, Li WA, Koshy ST, Weaver JC, Chaudhuri O, Granja PL, Mooney DJ. Influence of the stiffness of three-­‐dimensional alginate/collagen-­‐I interpenetrating networks on fibroblast biology. Biomaterials 2014;35:8927-­‐36. (IF 8.312) PDF 13. Maia FR, Barbosa M, Gomes DB, Vale N, Gomes P, Granja PL, Barrias CC. Hydrogel depots for local co-­‐delivery of osteoinductive peptides and mesenchymal stem cells. J Control Rel 2014;189:158-­‐168. (IF 7.261) PDF Pedro L. Granja n 19/41
14. Costa-­‐Almeida R, Guerreiro SG, Granja PL, Soares R. Cellular strategies to promote vascularization in tissue engineering applications. Eur Cell Mater 2014;28:51-­‐67. (IF 4.887) PDF 15. Maia FR, Beltrame KF, Rodrigues G, Granja PL, Barrias CC. Matrix-­‐driven formation of MSC-­‐
ECM microtissues on soft alginate hydrogels. Acta Biomater 2014;10:3197-­‐3208. (IF 5.684) PDF 16. Maia FR, Lourenço AH, Gonçalves RM, Granja PL, Barrias CC. Effect of cell density on mesenchymal stem cells aggregation in RGD-­‐alginate 3D matrices under osteoinductive conditions. Macromol Biosci 2014;14:759-­‐71. (IF 3.650) PDF 17. Moreira HR, Munarin F, Gentilini R, Visai L, Granja PL, Tanzi MC, Petrini P. Injectable pectin hydrogels produced by internal gelation: pH dependence of gelling and rheological properties. Carbohyd Polym 2014;103:339–347. (IF 3.916) PDF 18. Bidarra SJ, Barrias CC, Granja PL. Injectable alginate hydrogels for cell delivery in tissue engineering. Acta Biomater 2014;10:1646-­‐62. (IF 5.684) PDF 19. Fonseca KB, Gomes DB, Lee K, Santos SG, Sousa AF, Silva EA, Mooney DJ, Granja PL, Barrias CC. Injectable MMP-­‐sensitive alginate hydrogels as hMSC delivery systems. Biomacromolecules 2014;15:380-­‐90. (IF 5.788) PDF 20. Guerreiro SG, Oliveira MJ, Barbosa MA, Soares R, Granja PL. Neonatal human dermal fibroblasts immobilized in RGD-­‐alginate induce angiogenesis. Cell Transplant 2014;23:945-­‐
957. (IF 3.570) PDF 21. Maia FR, Bidarra SJ, Granja PL, Barrias CC. Functionalization of biomaterials with small osteoinductive moieties. Acta Biomater 2013;9:8773-­‐8789. (IF 5.684) PDF 22. Pereira RF, Barrias CC, Granja PL, Bartolo PJ. Advanced biofabrication strategies for skin regeneration and repair. Nanomedicine 2013;8:1-­‐19. (IF 5.824) PDF 23. Fonseca KB, Maia FR, Cruz FA, Andrade D, Juliano MA, Granja PL, Barrias CC. Enzymatic, physicochemical and biological properties of MMP-­‐sensitive alginate hydrogels. Soft Matter 2013;9:3283-­‐92. (IF 4.151) PDF 24. Guerreiro SG, Brochhausen C, Negrão R, Barbosa MA, Unger RE, Kirkpatrick CJ, Soares R, Granja PL. Implanted neonatal human dermal fibroblasts influence the recruitment of endothelial cells in mice. Biomatter 2012;2:1-­‐10. (No IF; starting journal) PDF 25. Munarin F, Petrini P, Tanzi MC, Barbosa MA, Granja PL. Biofunctional chemically modified pectin for cell immobilization. Soft Matter 2012;8:4731-­‐39. (IF 3.909) PDF 26. Salgado CL, Sanchez EMS, Zavaglia CAC, Granja PL. Biocompatibility and biodegradation of polycaprolactone-­‐sebacic acid blended gels. J Biomed Mater Res A 2012;100:243-­‐51. (IF 2.834) PDF 27. Salgado CL, Sanchez EMS, Zavaglia CAC, Almeida ABA, Granja PL. Injectable biodegradable polycaprolactone-­‐sebacic acid gels for bone tissue engineering. Tissue Eng A 2012;18:137-­‐46. (IF 4.065) PDF 28. Bidarra SJ, Barrias CC, Fonseca KB, Barbosa MA, Soares R, Granja PL. Evaluation of injectable in situ crosslinkable alginate matrix for endothelial cells delivery. Biomaterials 2011;32:7897-­‐
904. (IF 7.404) PDF 29. Bidarra SJ, Barrias CC, Barbosa MA, Soares R, Amédée J, Granja PL. Phenotypic and proliferative modulation of human mesenchymal stem cells via endothelial cell crosstalk. Stem Cell Res 2011;7:186-­‐97. (IF 5.127) PDF 30. Munarin F, Guerreiro S, Grellier M, Petrini P, Tanzi MC, Barbosa MA, Granja PL. Pectin-­‐based injectable biomaterials for bone tissue engineering. Biomacromolecules 2011;12:568-­‐77. (IF 5.479) PDF 31. Lopes JL, Machado JM, Castanheira L, Granja PL, Gama FM, Dourado F, Gomes JR. Friction and wear behaviour of bacterial cellulose against articular cartilage. Wear 2011;271:2328-­‐33. (IF 1.872) PDF Pedro L. Granja n 20/41
32. Fonseca KB, Bidarra SJ, Oliveira MJ, Granja PL, Barrias CC. Molecularly-­‐designed alginate hydrogels susceptible to local proteolysis as 3D cellular microenvironments. Acta Biomater 2011;7:1674-­‐82. (IF 4.865) PDF 33. Pandita D, Santos JL, Rodrigues J, Pêgo AP, Granja PL, Tomás H. Gene delivery into mesenchymal stem cells: a biomimetic approach using RGD nanoclusters based on poly(amidoamine) dendrimers. Biomacromolecules 2011;12:472-­‐81. (IF 5.479) PDF 34. Santos JL, Pandita D, Rodrigues J, Pêgo AP, Granja PL, Tomás H. Non-­‐viral gene delivery to mesenchymal stem cells: Methods, strategies and application in bone tissue engineering and regeneration. Curr Gene Ther 2011;11:46-­‐57. (IF 3.386) PDF 35. Cunha CB, Oliveira C, Wen X, Gomes B, Sousa S, Suriano G, Grellier M, Huntsman D, Carneiro F, Granja PL, Seruca R. De novo expression of CD44 variants in sporadic and hereditary gastric cancer. Lab Invest 2010;90:1604-­‐14. (IF 4.405) PDF 36. Bidarra SJ, Barrias CC, Barbosa MA, Soares R, Granja PL. Immobilization of human mesenchymal stem cells within RGD-­‐grafted alginate microspheres and assessment of their angiogenic potential. Biomacromolecules 2010;11:1956-­‐64. (IF 5.325) PDF 37. Santos JL, Pandita D, Rodrigues J, Pêgo AP, Granja PL, Balian G, Tomás H. Receptor-­‐mediated gene delivery using PAMAM dendrimers conjugated with peptides recognized by mesenchymal stem cells. Mol Pharm 2010;7:763-­‐74. (IF 5.400) PDF 38. Santos JL, Pandita D, Rodrigues J, Pêgo AP, Granja PL, Tomás H. Functionalization of poly(amidoamine) dendrimers with hydrophobic chains for improved gene delivery in mesenchymal stem cells. J Control Rel 2010;144:55-­‐64. (IF 7.164) PDF 39. Extremina CI, Freitas da Fonseca A, Granja PL, Fonseca AP. Anti-­‐adhesion and anti-­‐
proliferative cellulose triacetate membrane for prevention of biomaterial centered infections associated to Staphylococcus epidermidis. Int J Antimicrob Agents 2010;35:164-­‐8. (IF 3.787) PDF 40. Grellier M, Granja PL, Fricain J-­‐C, Bidarra SJ, Renard M, Bareille R, Bourget C, Amédée J, Barbosa MA. The effect of the co-­‐immobilization of human osteoprogenitors and endothelial cells within alginate microspheres on mineralization in a bone defect. Biomaterials 2009;30:3271-­‐8. (IF 7.365) PDF 41. Santos JL, Oramas E, Pêgo AP, Granja PL, Tomás H. Osteogenic differentiation of mesenchymal stem cells using PAMAM dendrimers as gene delivery vectors. J Control Rel 2009;134:141-­‐8. (IF 5.949) PDF 42. Barrias CC, Martins MCL, Almeida-­‐Porada G, Barbosa MA, Granja PL. The correlation between the adsorption of adhesive proteins and cell behaviour on hydroxyl-­‐methyl mixed self-­‐
assembled monolayers. Biomaterials 2009;30:307-­‐316. (IF 7.365) PDF 43. Evangelista MB, Hsiong S, Fernandes R, Sampaio P, Kong HJ, Barrias CC, Salema R, Barbosa MA, Mooney DJ, Granja PL. Upregulation of bone cell differentiation through immobilization within a synthetic extracellular matrix. Biomaterials 2007;28:3644-­‐55. (IF 6.262) PDF 44. Amaral IF, Granja PL, Melo LV, Saramago B, Barbosa MA. Functionalization of chitosan membranes through phosphorylation: Atomic Force Microscopy, wettability, and cytotoxicity studies. J Appl Polym Sci 2006;102:276-­‐84. (IF 1.306) PDF 45. Granja PL, De Jéso B, Bareille R, Rouais F, Baquey C, Barbosa MA. Cellulose phosphates as biomaterials. In vitro biocompatibility studies. React Funct Polym 2006;66:728-­‐39. (IF 1.561) PDF 46. Ferreira L, Evangelista MB, Martins MCL, Granja PL, Esteves JL, Barbosa MA. Improving the adhesion of poly(ethylene terephthalate) fibers to poly(hydroxyethyl methacrylate) hydrogels by ozone treatment: surface characterization and pull-­‐out tests. Polymer 2005:46;9840-­‐50. (IF 2.849) PDF 47. Amaral IF, Granja PL, Barbosa MA. Chemical modification of chitosan via phosphorylation. An XPS, FT-­‐IR and SEM study. J Biomater Sci Polym Edn 2005:16;1575-­‐93. (IF 1.409) PDF Pedro L. Granja n 21/41
48. Barrias CC, Granja PL, Lamghari M, Sá Miranda C, Barbosa MA. Biological evaluation of calcium alginate microspheres as a vehicle for the localized delivery of a therapeutic enzyme. J Biomed Mater Res 2005:Part A 74;545-­‐52. (IF 2.743) PDF 49. Granja PL, De Jéso B, Bareille R, Rouais F, Baquey C, Barbosa MA. Mineralization of regenerated cellulose hydrogels induced by human osteoprogenitor cells. Eur Cell Mater 2005:10;31-­‐9. (No IF; starting journal) PDF 50. Barbosa MA, Granja PL, Barrias CC, Amaral IA. Polyssacharides as scaffolds for bone regeneration. ITBM-­‐RBM 2005:26;212-­‐7. (No IF) PDF 51. Granja PL, Silva AIN, Borges JP, Barrias CC, Amaral IF. Preparation and characterization of injectable chitosan-­‐hydroxyapatite microspheres. Key Eng Mater 2004:254-­‐256;573-­‐6. (IF 0.278) PDF 52. Amaral IF, Granja PL, Barbosa MA. In vitro mineralisation of chitosan membranes carrying phosphate functionalities. Key Eng Mater 2004:254-­‐256;577-­‐80. (IF 0.278) PDF 53. Fricain JC, Granja PL, Barbosa MA, De Jéso B, Barthe N, Baquey C. Cellulose phosphates as biomaterials. In vivo biocompatibility studies. Biomaterials 2002:23;971-­‐80. (IF 3.008) PDF 54. Granja PL, Pouységu L, Pétraud M, De Jéso B, Baquey C, Barbosa MA. Cellulose phosphates as biomaterials. Synthesis and characterization of highly phosphorylated cellulose gels. J Appl Polym Sci 2001:82;3341-­‐53. (IF 0.992) PDF 55. Granja PL, Pouységu L, Deffieux D, Daudé G, De Jéso B, Labrugère C, Baquey C, Barbosa MA. Cellulose phosphates as biomaterials. Surface chemical modification of regenerated cellulose hydrogels. J Appl Polym Sci 2001:82;3354-­‐65. (IF 0.992) PDF 56. Granja PL, Pouységu L, De Jéso B, Rouais F, Baquey C, Barbosa MA. Cellulose phosphates as biomaterials. Mineralization of chemically modified regenerated cellulose hydrogels. J Mater Sci 2001;36:2163-­‐72. (IF 0.728) PDF 57. Granja PL, Ribeiro CC, De Jéso B, Baquey C, Barbosa MA. Mineralization of regenerated cellulose hydrogels. J Mater Sci: Mater Med 2001;12:785-­‐91. (IF 1.144) PDF 58. Fonseca AP, Granja PL, Nogueira JA, Barbosa MA. Adhesion of Staphylococcus epidermidis RP62A to cellulose derivatives compared to commercial polymeric biomaterials. J Mater Sci: Mater Med 2001;12:543-­‐8. (IF 1.144) PDF PATENT •
Salgado CL, Sanchez EMS, Granja PL, Zavaglia CAC. Preparation method of injectable biodegradable polymer (Método de confecção de polímero biodegradável injetável). Patent Nr. WO 2010034089 (2010-­‐04-­‐01); Patent Nr. BR PI0805750 (2010-­‐08-­‐24). OTHER PUBLICATIONS •
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Granja PL. Inclusion of Biomatter in Medline (Index Medicus). Biomatter 2013;3:e24610. PDF Granja PL. Welcome to Biomatter. Biomatter 2011;1:1. PDF Lopes JL, Dourado F, Machado JM, Granja PL, Gama FM, Gomes JR. Tribological Properties of Bacterial Cellulose in Reciprocating Sliding Against Bovine Articular Cartilage. Nordtrib 2010 -­‐ 14th Nordic Symposium on Tribology, 8 pp. Storforsen, Sweden, June 2010. PDF Lopes JL, Rybolova P, Granja PL, Gomes JR. Tribological response of pHema-­‐based hydrogels against bovine cartilage. IBERTRIB 2009 – V Iberian Congress on Tribology. Coimbra, Portugal: June 17-­‐18, 2009. PDF Granja PL. The involution of Portuguese Science. The Biochemist 2005;27:43-­‐44. PDF Yunzhi Y, Jiemo T, Granja PL. Biomaterials Network www.biomat.net is online. Chinese Journal of Biomedical Engineering 2000;19:359-­‐360. PDF Granja PL, Pouységu L, Pétraud M, Deffieux D, Bareille R, Poustis J, Barbosa MA, Baquey C, De Pedro L. Granja n 22/41
Jéso B. Biomatériaux Cellulosiques pour la Régénération Osseuse. Lettres des Pôles GBM et Médicament en Aquitaine 1996;17:27-­‐32. ABSTRACTS IN REFEREED JOURNALS •
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Costa-­‐Almeida R, Lazaro M, Soares R, Guerreiro SG, Granja PL. Interactions between dermal fibroblasts and endothelial cells in vascularization for tissue engineering applications. J Tissue Eng Regen Med 2014;8:S211-­‐2. KB Fonseca, PL Granja, CC Barrias. Physico-­‐chemical and enzymatic properties of PVGLIG and PVGLIG-­‐alginate hydrogels. J Tissue Eng Regen Med 2012;6:S208. Guerreiro SG, Unger RE, Sartoris A, Martins MJ, Barbosa MA, Soares R, Granja PL, Kirkpatrick CJ. Crosstalk between fibroblasts and endothelial cells promotes angiogenesis in vitro: putative role of alkaline phosphatase. J Tissue Eng Regen Med 2012;6:S313-­‐4. Bidarra S, Fonseca KB, Granja PL, Barrias CC. Learning from the cell-­‐matrix crosstalk to improve a cell delivery system based on RGD-­‐modified alginate. J Tissue Eng Regen Med 2012;6:S184-­‐5. Guerreiro SG, Unger RE, Sartoris A, Martins MJ, Barbosa MA, Soares R, Granja PL, Kirkpatrick CJ. Crosstalk between fibroblasts and endothelial cells promotes angiogenesis in vitro: putative role of alkaline phosphatase, growth factors and collagen. Bull Group Int Rech Sci Stomatol Odontol 2012;51:29. Fonseca KB, Granja PL, Barrias CC. Physico-­‐chemical and enzymatic properties of PVGLIG and PVGLIG-­‐alginate hydrogels. J Tissue Eng Regen Med 2012;6:S208. Guerreiro S, Negrao R, Oliveira MJ, Barbosa MA, Soares R, Granja PL. Modulation of angiogenesis by fibroblasts in tissue regeneration. Int J Artif Organs 2011;34:S691. Bidarra SJ, Barrias CC, Barbosa MA, Soares R, Granja PL. Upregulation of mesenchymal stem cells differentiation and proliferation in coculture with endothelial cells. Tissue Eng A 2008;14:S793. Grellier M, Bidarra SJ, Bareille R, Fricain JC, Granja PL, Barbosa MA, Amedee J. Encapsulation of osteoprogenitor and endothelial cell co-­‐cultures for bone tissue engineering application. Bone 2008;42:S22. Santos JL, Rodrigues J, Pêgo AP, Granja PL, Tomás H. Novel conjugates of dendrimers and fatty acids for gene delivery applications. Tissue Eng A 2008;14:S888-­‐9. Sargo S, Santos JL, Rodrigues J, Pêgo AP, Granja PL, Tomás H. New Pamam dendrimers/alginate nanoparticles for gene delivery. Tissue Eng A 2008;14:S886. Grellier M, Bourge C, Bareille R, Granja PL, Barbosa MA, Amedee J. Cell cooperation between Human OsteoProgenitor cells and endothelial cells in tissue engineering. J Bone Min Res 2007;22:S93. Grellier M, Bareille R, Bourget C, Ferreira Tojais N, Granja PL, Barbosa MA, Amédée J. Cell Cooperation Between Human Osteoprogenitor and Endothelial Cells: its Function on Bone Tissue Engineering. Eur Cells Mater 2007;14(Suppl. 1):33. Bidarra Sj, Barrias CC, Barbosa MA, Soares R, Granja PL. Immobilization of human mesenchymal stem cells. Eur Cells Mater 2007;14(Suppl. 1):52. Granja PL, Evangelista MB, Bidarra SJ, Guerreiro SG, Barrias CC, Mooney DJ, Barbosa MA. Injectable cell immobilization systems for bone regeneration. Eng Biomater;10:S5-­‐6. Extremina CI, Granja PL, da Fonseca AF, Fonseca AP. Adhesion of staphylococcus epidermidis to a modified cellulose triacetate membrane. Int J Antimicrob Agents 2007;29(Suppl. 2):S143-­‐
4. BOOKS •
INEB 25 Years. Porto: INEB. 2014. Pedro L. Granja n 23/41
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Pêgo AP, Pina F, Granja PL, Pinto do Ó P. Biomagical Engineering: INEB 20 Years. Porto: INEB. 2009. BOOK CHAPTERS •
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Mosqueira D, Amaral IF, Granja PL, Pinto-­‐do-­‐Ó P. A Mecânica da Vida. In: Barbedo de Magalhães A, editor. Introdução À Engenharia Mecânica. In Press (2014). Granja PL, Barrias CC, Amaral IF, Barbosa MA. Biomateriais políméricos naturais (Chap. 2). In: Gil MH and Sardinha JP, editors. Biomateriais: Conceitos e Aplicações. Lisbon, Portugal: Lidel. In Press (2014). Araújo F, Pereira C, Santos H, Granja PL, Sarmento B, Functionalized nanoparticles for targeting the gastrointestinal apical membrane receptors. In: De Vooght-­‐Johnson R, editor. Advances and challenges in oral delivery of macromolecules. Future Science, In Press (2013). Granja PL, Pereira JP, Barbosa MA. The Biomaterials Network (Biomat.net) as a major internet resource for biomaterials, tissue engineering and biomineralization (Chap. 24). In: Epple M and Baeuerlein E, editors. Handbook of Biomineralization, Vol. 3: Medical and Clinical Aspects. Wiley-­‐VCH. 2007. Barbosa MA, Jian J, Granja PL, Martins CL. Engenharia de biomateriais à escala molecular. In: Ferreira PJ and Fortes A, editors. Materiais 2000. Lisbon, Portugal: IST Press; 2003. p. 391-­‐399. Amaral IF, Barbosa MA, Barrias CC, Cavalheiro J, Ferraz MP, Granja PL, Lopes MA, Martins CL, Monteiro FJ, Ribeiro CC, Santos JD, Sousa SR, Queiroz AC. Biomateriais (Chap. 18). In: Lima N and Mota M, editors. Biotecnologia: Fundamentos e Aplicações. Lisbon, Portugal: Lidel; 2003. p. 377-­‐397. Granja PL, Barbosa MA, Pouységu L, De Jéso B, Baquey C. Cellulose Phosphates as Biomaterials. In: Ottenbrite RM, editor. Frontiers in Biomedical Polymers Applications 2. Lancaster, PA: Technomic Press; 1999. p. 195-­‐225. Reis RL, Granja PL, Cunha AM. Impact Behaviour of UHMWPE/HA Composites for Orthopaedic Prostheses. In: Chielini E, Cohn D, Migliaresi C, Ottenbrite RM and Sunamoto J, editors. Frontiers in Biomedical Polymers Applications 1. Lancaster, PA: Technomic Press; 1998. p. 251-­‐
263. Granja PL, Baquey C, Pouységu L, Bareille R, De Jéso B, Barbosa MA. Cellulose-­‐based Biomaterials for Bone Regeneration: Hemi-­‐synthesis and Characterisation. Polymers in Medicine and Surgery -­‐ PIMS’96. Glasgow, UK: Institute of Materials; 1996. p. 73-­‐80. Cunha AM, Reis RL, Granja PL, Ferreira FG. Influence of Processing Conditions on the Mechanical Behavior of UHMWPE/HA and PMMA/HA Composites. In: Kossowiski R and Kossowiski N, editors. Materials Science and Implant Orthopaedic Surgery II, NATO/ASI series (E:Applied Sciences). Kluwer Academic Publishers; 1995. p. 163-­‐176. THESES •
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Granja PL. Biomimetic Natural Materials for Bone Regeneration. PhD Thesis. Faculdade de Engenharia da Universidade do Porto (FEUP), Porto, 2001. Ferreira F, Granja PL. Bioreactive Polymer/Ceramic Composites. Graduation thesis. Departamento de Engenharia Metalúrgica e de Materiais (DEMM), Faculdade de Engenharia da Universidade do Porto (FEUP), Porto, 1993. COMMUNICATIONS ORAL COMMUNICATIONS BY INVITATION Pedro L. Granja n 24/41
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3D cell carriers for regenerative therapies. Faculty of Medicine of the University of Porto. Porto: January 14, 2015. Designer hydrogels as 3D cellular microenvironments. 4th Advanced Course on regenerative Medicine. Centre for Rapid and Sustainable Product Development (CDRsp), Polytechnic Institute of Leiria (IPL). Leiria: December 12, 2014. Publishing Science. University of Valladolid. Valladolid, Spain: October 22, 2014. Cell Biology in 3D. European Space Research and Technology Centre, European Space Agency (ESA). Noordvijk, The Netherlands: September 10, 2014. Cell Biology in 3D. University of Twente, Institute of Biomedical Technology & Technical Medicine (MIRA). Enschede, The Netherlands: July 3, 2014. Tissue Engineering alternatives to animal procedures. XVII Course in Laboratory Animal Science. IBMC.INEB, Porto: May 12, 2014. INEB – Instituto de Engenharia Biomédica. Alliance for Cooperation in Engineering (ACE) Forum. FEUP, Porto: May 6, 2014. Biofunctional hydrogels for tissue engineering. Campinas University (UNICAMP), Faculty of Medical Sciences. Campinas, SP, Brazil: Apr 28, 2014. Cell biology in 3D. Federal University of São Paulo (UNIFESP), Dept. Biphysics. São Paulo, SP, Brazil: Apr 25, 2014. Biofunctional hydrogels for tissue engineering (Keynote Lecture). IX Meeting of Materials Engineering. Mackenzie Presbyterian University. São Paulo, SP, Brazil: Apr 23, 2014. How to publish in high quality scientific journals? BiotechHealth -­‐ International Doctoral Program In Molecular And Cellular Biotechnology Applied To Health Sciences. ICBAS, University of Porto. Porto: Feb 18-­‐20, 2014. Cell behavior in the third dimension. New Therapies and Technologies Course, Graduate Program in Areas of Basic and Applied Biology (GABBA), University of Porto. Porto: Feb 19, 2014. Biology in 3D. Friday Noon Seminars. Institute for Molecular and Cell Biology (IBMC)-­‐Institute for Biomedical Engineering (INEB), Porto: Jan 17, 2014. Engineering cell-­‐materials interactions at the molecular level. 1st Cluster Workshop in Materials and nanotechnology. Instituto Superior Técnico (IST)/University of Lisbon, Lisbon: Dec 4, 2013. Biofunctional hydrogels for tissue engineering. University of Aveiro. Aveiro: Nov 26, 2013. Regenerative Medicine in future health care. Federal University of Minas Gerais. Belo Horizonte, MG, Brazil: Oct 4, 2013. Biofunctional hydrogels for tissue engineering. XII Brazilian MRS Meeting. Campos do Jordão, SP, Brazil: Oct 1, 2013. Regenerative materials. XII Brazilian MRS Meeting. Campos do Jordão, SP, Brazil: Sep 30, 2013. Biomaterials and Regenerative Medicine in future health care. Faculty of Engineering, São Paulo State University (UNESP). Guaratinguetá, SP, Brazil: Sep 27, 2013. Regenerative Medicine in future health care. São Paulo State University (UNESP). Bauru, SP, Brazil: Sep 26, 2013. Functional Biomaterials for Regenerative Medicine. Federal University of São Carlos (UFSCar). São Carlos, SP, Brazil: Sep 25, 2013. Biomagical Engineering. School of Engineering of São Carlos, University of São Paulo (USP). São Carlos, SP, Brazil: Sep 25, 2013. Regenerative Medicine strategies for stem cell transplantation and delivery. Faculty of Veterinary Medicine and Animal Sciences, University of São Paulo (USP). São Paulo, Brazil: Sep 24, 2013. Pedro L. Granja n 25/41
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Building a career as a biomaterials scientist. Young Scientists Forum @ ESB2013. 25th European Conference on Biomaterials. Madrid, Spain: Sep 8, 2013. Tissue engineering strategies for stem cell transplantation and delivery. I International Conference on Stem Cells for Drug Screening and Regenerative Medicine. Coimbra: July 19, 2013. Regenerative medicine in future health care. Integrated MSc in Biomedical Engineering. University of Minho, Braga: May 30, 2013. Biofunctional hydrogels for tissue engineering. Integrated MSc in Medicine, Histology and Embryology of Organs and Systems. Faculty of Medicine of the University of Porto, Porto: May 28, 2013. Engineering stem cell fate through cell-­‐matrix interactions. 8th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies. Faro: May 9, 2013. Biomedical sciences and engineering. VII Jornadas de Ciências. Cooperativa de Ensino Superior, Politécnico e Universitário (CESPU). Porto: Apr 20, 2013. Scientific and social impact of medical technologies of the future: Implications on human enhancement. Round table on Human enhancement and challenges of ageing. AEICBAS Biomedical Congress: AN innovative approach to life sciences, University of Porto. Porto: Apr 7, 2013. Biofunctional hydrogels for cell entrapment and delivery. New Therapies and Technologies Course, Graduate Program in Areas of Basic and Applied Biology (GABBA), University of Porto. Porto: Mar 12, 2013. Engineered hydrogels for bone tissue regeneration. University of Aveiro. Aveiro: November 27, 2012. From Biomaterials to Regenerative Medicine. University of Aveiro. Aveiro: November 27, 2012. Perspectives on Bioengineering research in Portugal. 4th Symposium on Bioengineering. Faculty of Engineering, University of Porto (FEUP). Porto: November 24, 2012. Regenerative Medicine and the future of healthcare. Jornadas de Biotecnologia 2012. Universidade Católica. Porto: November 13, 2012. Advanced biofunctional polymers for tissue engineering. BIN@Porto (Business and Innovation Network) 2012. Porto: October 25, 2012. Engineering cell-­‐matrix interactions. TERM STEM 2012. Guimarães: October 12, 2012. Injectable systems for tissue engineering. Devices for Regenerative Medicine: from the design to the evaluation. Bordeaux, France: September 27, 2012. Engineering cell-­‐instructive microenvironments with molecularly-­‐designed hydrogels. Biologically Oriented Materials Group, ETH Zurich. Zurich, Switzerland: June 18, 2012. Biofunctional hydrogels for Tissue Engineering. III International Forum of Biomedical Materials: Nanobiomaterials for Tissue Regeneration, Zhejiang University. Hangzhou, China: May 31, 2012. Hydrogels for cell delivery in bone regeneration. III Jornadas de Ciência e Medicina. Escola de Ciências da Saúde, Universidade do Minho. Braga: Apr 14, 2012. How to regenerate human tissues and organs? (Como regenerar tecidos e órgãos humanos?). Controvérsias ao almoço: Factos e Mitos em Medicina Regenerativa. Hospital de Santo António, Porto: Apr 4, 2012. Biofunctional hydrogels for bone tissue engineering. III International Biomaterials Course – Advances in Biomaterials and Nanbiotechnology. UNESCO Biomaterials Chair, University of Havana. Havana, Cuba: Mar 21, 2012. From biomaterials to regenerative medicine (Dos biomateriais à medicina regenerativa). IV Jornadas Nacionais de Ciências Biomédicas. Universidade do Algarve, Faro: Mar 15, 2012. Regenerative Medicine and the Man of the Future (A Medicina Regenerativa e o Homem do Pedro L. Granja n 26/41
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Futuro). IV Jornadas Nacionais Genética e Biotecnologia. Universidade de Trás-­‐os-­‐Montes e Alto Douro (UTAD), Vila Real: Mar 2, 2012. Functionalized materials for cell therapies in bone tissue engineering. 2nd International Conference on Nanotechnology at the Bio-­‐Medical Interface -­‐ Nanobio 2012. Kochi, India: Feb 22, 2012. Bone Tissue Engineering. Cell and Tissue Engineering Advanced Course, Biocant, University of Coimbra: Feb 16, 2012. Biofunctional hydrogels for cell entrapment and delivery. New Therapies and Technologies Course, Graduate Program in Areas of Basic and Applied Biology (GABBA), University of Porto. Porto: Feb 14, 2012. Biofunctional hydrogels for cell entrapment and delivery. 2nd Advanced Course on Regenerative Medicine. Centre for Rapid and Sustainable Product Development (CDRsp), Polytechnic Institute of Leiria (IPL). Leiria: Feb 9, 2012. Biomaterials, Tissue Engineering and Regenerative Medicine. III Seminário de Bioengenharia. Escola Superior de Tecnologia e Gestão, Intituto Politécnico de Portalegre: Dec 13, 2011. Injectable biofunctional hydrogels for cell entrapment and delivery. MIT-­‐Portugal Doctoral Programmes – Nanobiotechnology and Biomaterials. 3B’s Research Group and European Institute of Excellence on Tissue Engineering and Regenerative Medicine, University of Minho. Guimarães: Dec 6, 2011. Regenerative Medicine. Catholic University. Porto: Dec 5, 2011. Regenerative Medicine and the Man of the Future (A Medicina Regenerativa e o Homem do Futuro). Seminar Series on Philosophy and Technological Condition. Philosophy and Public Space research group, Faculdade de Letras da UPorto. Porto: Nov 25, 2011. Regenerative future (Opening Keynote Lecture). Biofuture 2011. Ghent, Belgium: Nov 16, 2011. Why become a scientist. III Jornadas de Bioengenharia. Porto: Oct 14, 2011. Regenerative medicine in oncology. Instituto Português de Oncologia (IPO)-­‐Porto. Porto: May 30, 2011. Tissue engineering and regenerative medicine. IV Xornadas de Investigación Biomédica de Vigo. Vigo: May 24, 2011. Why and how to publish scientific papers? Workshop on Research Supporting Tools, MSc in Clinical Microbiology, Faculty of Health Sciences, Fernando Pessoa University. Porto: May 20, 2011. Regenerative Medicine and the Man of the Future (A Medicina Regenerativa e o Homem do Futuro). Knowledge at U.Porto -­‐ University of Porto’s Centennial Conferences. Porto: May 12, 2011. From biomaterials to Tissue Engineering (Dos biomateriais à engenharia de tecidos). Externato Ribadouro. Porto: May 10, 2011. (Keynote Lecture). Injectable biomaterials for bone regeneration. VI International Materials Symposium Materiais 2011-­‐XV Meeting of SPM (Portuguese Materials Society). Guimarães: Apr 20, 2011. Tissue engineering strategies for bone regeneration. New Therapies and Technologies Course, Graduate Program in Areas of Basic and Applied Biology (GABBA), University of Porto. Porto: Apr 13, 2011. 3D structures for cellular therapies in tissue regeneration. CICECO, Ceramics and Glass Engineering Department, University of Aveiro. Aveiro: Mar 31, 2011. Current trends and challenges in multifunctional biomaterials for tissue engineering and regenerative medicine. International Doctoral School in Functional Materials (IDS-­‐FUNMAT). Lisbon: Mar 15, 2011. Pedro L. Granja n 27/41
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Regenerative Medicine. Catholic University. Porto: Dec 14, 2010. Cell immobilization systems for bone tissue regeneration. 4th International Conference “Biomaterials, Tissue Engineering & Medical Devices” -­‐ BiomMedD’2010. Sinaia, Romania: Sep 24, 2010. Cell therapy research strategies. Semmelweis Innovations BioEntrepreneurship Program -­‐ SIBE 2010-­‐2011. Budapest, Hungary: Sep 22, 2010. Nanostructured materials for tissue regeneration. Ciência 2010. Lisbon: Jul 5, 2010. Angiogenesis in Bone Regeneration. Faculty of Medicine, University of Porto. Porto: Jun 29, 2010. Nanobiotechnology and Biomaterials + Functionalized nanostructures for tissue regeneration. Nanotechnology, Drug Delivery and Drug Targeting Course. Faculty of Pharmacy, University of Porto. Porto: May 21, 2010. Injectable biomaterials for bone regeneration. Jornadas de Engenharia Química e Biológica (JEQB) 2010. Instituto Superior Técnico (IST). Lisbon: Apr 12, 2010. Fundamentals of biomaterials science and engineering. New Therapies and Technologies: Nanoscience and Nanotechnology for tissue engineering and regeneration. Biomaterials in Tissue Regeneration Course, Graduate Program in Areas of Basic and Applied Biology (GABBA), University of Porto. Porto: Mar 29, 2010. Injectable Systems for Tissue Engineering. I Jornadas Nacionais de Ciências Biomédicas. Universidade de Aveiro. Aveiro: Mar 12, 2010. Biomaterials for Regenerative Medicine. Universidade de Trás-­‐os-­‐Montes e Alto Douro (UTAD). Vila Real: Feb 24, 2010. Immobilized stems cells for tissue regeneration. MIT-­‐Portugal Doctoral Programmes – Nanobiotechnology and Biomaterials. European Institute of Excellence on Tissue Engineering and Regenerative Medicine, University of Minho. Braga: Dec 10, 2009. Regenerative Medicine. iMED – Inovar a Medicina. Universidade Nova de Lisboa. Lisbon: Nov 7, 2009. Regenerative Medicine. Universidade Católica. Porto: Nov 5, 2009. Social Impact of Regenerative Medicine. BRIDGE Summer Course on Biomaterials and Regenerative Medicine. Madeira: Sep 12, 2009. Cell interactive systems for bone tissue regeneration. Ciência 2009. Lisbon: Jul 29, 2009. Cellulose Phosphate as a Biomaterial. University of Paris 13. Paris, France: Jul 15, 2009. Cell immobilization strategies for bone tissue regeneration. Laboratoire de Biomatériaux et Polymères de Specialité (LBPS), University of Paris 13. Paris, France: Jul 9, 2009. Fundamentals of biomaterials science and engineering. Graduate Program in Areas of Basic Applied Biology (GABBA). Porto: May 5, 2009. Injectable systems for bone regeneration. 2nd Workshop on Biotribology. Guimarães: May 26, 2009. Angiogenesis in Bone Regeneration. Faculty of Medicine, University of Porto. Porto: May 22, 2009. Decoding man as a machine. Jornadas "Ciência -­‐ A Causa das Coisas”. Porto: Apr 17, 2009. How far to Humans 2.0. IV National Meeting of Biomedical Engineering Students (ENEEB). Coimbra: Apr 16, 2009. Lab-­‐made organs and tissues. Institute for Medicines and Pharmaceutical Sciences (iMed.UL), Faculty of Pharmacy, Lisbon University. Lisbon: Mar 27, 2009. Cell immobilization systems for tissue engineering. Institute of Bioengineering (IBI), École Polytechnique Fédérale de Lausanne (EPFL). Lausanne, Switzerland: Mar 19, 2009. Cell seeding strategies in bone grafting. BRIDGE-­‐SIROT Symposium -­‐ Recent Innovations in Pedro L. Granja n 28/41
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Bone and Joint Regeneration. Budapest, Hungary. Feb 7, 2009. Humans 2.0. III Jornadas Concelhias de Ciência. Externato Delfim Ferreira. Riba D’Ave: Jan 15, 2009. Biomaterials and the Future of Medical Technology. Escola Superior de Estudos Industriais e Gestão (ESEIG), Instituto Politécnico do Porto (IPP). Porto: Jan 5, 2009. The Promises of Regenerative Medicine. VI Encontro do Fórum Internacional de Investigadores Portugueses (FIIP 2009) – Brain, Life and Culture. Lisbon: Dec 19, 2008. Regenerative Medicine. Universidade Católica. Nov 27, 2008. Lab-­‐made tissues. Universidade de Coimbra. Coimbra: Nov 20, 2008. Regenerative Materials. II Encontro Nacional de Estudantes de Materiais (ENEM). University of Minho. Guimarães: Nov 7, 2008. Tissue engineered bone. I3S Workshop on Regeneration. INEB. Porto: Oct 27, 2008. Angiogenesis in Bone Regeneration. Faculty of Medicine, University of Porto. Porto: Jun 12, 2008. Biomaterials in Hip Prostheses. BioM’08. Escola Superior de Estudos Industriais e de Gestão (ESEIG), Instituto Politécnico do Porto (IPP). Porto: May 14, 2008. Fundamentals of biomaterials science and engineering. Graduate Program in Areas of Basic Applied Biology (GABBA). Porto: May 12, 2008. Endothelial Cells in Bone Regeneration. Portuguese Oncology Institute (IPO)-­‐Lisbon. Lisbon: Apr 16, 2008. Biomedical Engineering (Engenharia Biomédica). Escola Secundária Alexandre Herculano. Porto (07/03/2008). Human Tissues Made in the Laboratory. Centro de Química da Madeira, University of Madeira. Funchal, Madeira: Feb 12, 2008. Engineered Cell Immobilization Systems. Research Center on Artificial Biopolymers, University Montpellier 1. Montpellier, France: Nov 23, 2007. Tissue Engineered Injectable Cell Immobilization Systems. INSERM U577, University Victor Ségalen Bordeaux 2. Bordeaux, France: Nov 16, 2007. Regenerative Medicine. I Jornadas Biomédicas. Universidade da Beira Interior. Covilhã: Nov 9, 2007. Conference on Biomaterials in Medicine and Veterinary Medicine, Rytro, Poland: Oct 11-­‐14, 2007. Injectable tissue engineered cell immobilization systems. 7th International Symposium on Frontiers in Biomedical Polymers. Ghent, Belgium: Jun 24-­‐27, 2007. Bioengineering (Bioengenharia). Escola Secundária de Seia. Seia (24/05/2007). Fundamentals of biomaterials science and engineering. Graduate Program in Areas of Basic Applied Biology (GABBA). Porto: May 21-­‐25, 2007. Injectable tissue engineered cell encapsulation systems. Bioencapsulation. COST Action 865. Lisbon: Apr 26-­‐27, 2007. Live Engineering. II Jornadas Concelhias de Ciência. Externato Delfim Ferreira. Riba D’Ave: Feb 23, 2007. Tissue engineering as a revolution in health care. Faculty of Sciences, University of Porto. Porto: Nov 20, 2006. Regenerative Chemistry (Química Regenerativa). Chemistry is Fun (A Química é Divertida). Madeira Magic/Centro de Química da Madeira (University of Madeira). Funchal, Madeira (23/11/2006). (Jean Leray Award Lecture, 2006). Unravelling Injectable Biomaterials for Orthopedic Applications. 20th European Conference on Biomaterials. Nantes, France: Sep 30, 2006. Pedro L. Granja n 29/41
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Tissue Engineering and Regenerative Medicine. From Science to Medicine Workshop, IBMC, Porto: Sep 5, 2006. The rising impact of Tissue Engineering. IV Latin American Congress of Biomaterials and Artificial Organs (COLAOB 2006). Caxambú, Minas Gerais, Brazil: Aug 8-­‐11, 2006. Endeavors, Pitfalls and Accomplishments of Tissue Engineering. 7th Advanced Course in Cell-­‐
Material Interactions. Bilbioteca Almeida Garret, Porto: Jun 19–23, 2006. Cell Encapsulation for Regenerative Therapies. 7th Advanced Course in Cell-­‐Material Interactions. Bilbioteca Almeida Garret, Porto: Jun 19–23, 2006. Revisiting the protein-­‐material interfacial chemistry. International Conference on Advances in Biomaterials for Drug Delivery and Regenerative Medicine. Capri, Italy: Jun 11-­‐16, 2006. Tissue engineered injectable biomaterials for bone regenerative medicine. GABBA Annual Symposium “Biotechnology in Health”. IPATIMUP, Porto: Jun 12, 2006. Regenerative Medicine. Jornada de Biomateriais. Universidade de Coimbra, Coimbra: Apr 19, 2006. Engineering in Regenerative Medicine. IV Conferências de Engenharia Mecânica e Gestão Industrial. Escola Superior de Tecnologia de Viseu, Viseu: Apr 11, 2006. The revolution of Regenerative Medicine. Biology in Regenerative Medicine Workshop. X Encontro Nacional de Estudantes de Biologia. IBMC-­‐INEB, Porto: Apr 8, 2006. Injectable biomaterials for bone regeneration. Brazilian MRS Meeting 2005 – IV SPBMat05. Recife, Brazil: Oct 16-­‐19, 2005. Young Scientists Forum: Past, present and future. 4th Young Scientists Forum, integrated in the 19th European Conference on Biomaterials. Sorrento, Italy: Sep 13, 2005. Young Scientists Forum. BioÉvora 2004 – 2nd Iberian Congress on Biomaterials. Évora: Sep 9-­‐
11, 2004. The role of Biomedical Engineering on the improvement of healthcare. III Engineering Week, Escola Superior de Tecnologia de Abrantes. Abrantes: May 8, 2003. The role of Biomedical Engineering on the improvement of healthcare. Mostra de Ciência, Ensino e Inovação da UP. Porto: Mar 21, 2003. The relevance of communicating the value of medical technology. Biocities 2002. Lisbon: Nov 28-­‐29, 2002. Tissue engineering in sports medicine. 25 Symposium de la Sociedad Ibérica de Biomecánica y Biomateriales. Granada, Spain: Nov 22-­‐23, 2002. Natural polymers in Biomedical Applications. 3rd Advanced Course in Biomaterials. Porto: Jul 1-­‐5, 2002. Natural polymers as biomaterials. Materials Research Center (CENIMAT), Dept. Materials Science, Universidade Nova de Lisboa. Lisbon: Apr 23, 2002. Natural polymers as biomaterials. Biomaterials: Development and Applications. Coimbra: Apr 12, 13, 19, 20, 2002. The Biomaterials Network (Biomat.net): Objectives, Activities and Future Goals. Biocities 2001. Hamburg, Germany: Oct 11-­‐12, 2001. Cellulose phosphates as biomaterials. Synthesis and biological behavior evaluation. CERC3 Workshop, Functional Polymers. Nijmegen, The Netherlands: Mar 1-­‐3, 2001. Hydrogels and Natural Polymers. Advanced Course on Biomaterial-­‐Cells Interactions. Porto: Jun 12-­‐14, 2000. Cellulose phosphates as biomaterials. Zhejiang University. Hang Zhou, China: Oct 2000. Cellulose phosphates as biomaterials; and Biomaterials Network (Biomat.net). Fudan University. Shanghai, China: Oct 2000. Establishment of an European PhD in Biomaterials. 15th European Conference on Biomaterials. Pedro L. Granja n 30/41
Bordeaux, France: Sep 8-­‐12, 1999. ORAL COMMUNICATIONS •
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Wahaia F, Kasalynas I, Seliuta D, Molis G, Urbanowicz A, Silva CDC, Carneiro F, Valusis G, Granja PL. Study of gastric cancer samples using terahertz techniques. II International Conference on Applications of Optics and Photonics. Aveiro, Portugal: May 26-­‐30, 2014. Neves SC, Bidarra SJ, Barrias CC, Granja PL. Pectin-­‐based hydrogels for tissue engineering applications. 4th china-­‐Europe Symposium on Biomaterials in regenerative Medicine. Sorrento, Italy: July 1-­‐4, 2013. Fonseca KB, Gomes DB, Granja PL, Barrias CC. MMP-­‐sensitive alginate hydrogels as injectable vehicles for MSC delivery. European Chapter Meeting of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-­‐EU 2013). Istanbul, Turkey: Jun 17-­‐20, 2013. Neves SC, Barrias CC, Granja PL. Pectin-­‐based hydrogels for tissue engineering applications. International Conference on Tissue Engineering. Leiria: June 6-­‐8, 2013. Costa-­‐Almeida R, Guerreiro SG, Granja PL, Soares R. Vascularization in tissue engineering: Crosstalk between tissue cells and endothelial cells. International Conference on Tissue Engineering. Leiria: June 6-­‐8, 2013. Bidarra S, Fonseca K, Granja PL, Barrias CC. Learning from the cell-­‐matrix crosstalk to improve a cell delivery system based on RGD-­‐ modified alginate. 3rd TERMIS World Congress 2012 “Tissue Engineering and Regenerative Medicine”. Vienna, Austria: September 5-­‐8, 2012. Bidarra SJ, Barrias CC, Fonseca KB, Barbosa MA, Soares R, Granja PL. Angiogenic potential of cell-­‐loaded injectable RGD-­‐modified alginate. 9th World Biomaterials Congress. Chengdu, China: June 1-­‐5, 2012. Da Cunha CB, Granja PL, Mooney DJ. Culture dimensionality controls the expression of CD44 receptors. Signal transduction by engineered extracellular matrices. Gordon Research Conferences 2012, University of New England. Biddeford, USA: June 8-­‐13, 2012. Guerreiro SG, Unger RE, Sartoris A, Martins MJ, Barbosa MA, Soares R, Granja PL, Kirkpatrick CJ. Crosstalk between fibroblasts and endothelial cells promotes angiogenesis in vitro: putative role of alkaline phosphatase, growth factors and collagen. Sixth International Alkaline Phosphatase and Hypophosphatasia Symposium: From Bench to bedside. Huningue, France: May 16-­‐18, 2012. Bidarra SJ, Guerreiro SG, Barrias CC, Barbosa MA, Granja PL. Cooperação entre células ósseas e vasculares na regeneração óssea (Cooperation between bone and vascular cells in osseous regeneration). XXXI National Congress of Orthopedics and Traumatology. Estoril: October 19-­‐
21, 2011. Barrias CC, Fonseca KB, Bidarra SJ, Barbosa MA, Granja PL. Biomateriais injectáveis multifuncionais para regeneração óssea (Injectable multifunctional biomaterials for bone regeneration). XXXI National Congress of Orthopedics and Traumatology. Estoril: October 19-­‐
21, 2011. Bidarra SJ, Barrias CC, Fonseca KB, Barbosa MA, Soares R, Granja PL. In vitro potential of a natural injectable RGD-­‐alginate hydrogel to deliver endothelial cells. 24th European Conference on Biomaterials. Dublin, Ireland: September 4-­‐8, 2011. Munarin F, Granja PL, Barbosa MA, Tanzi MC, Petrini P. RGD-­‐grafted pectin microspheres for human mesenchymal stem cell delivery and in situ bone regeneration. 24th European Conference on Biomaterials. Dublin, Ireland: September 4-­‐8, 2011. SJ Bidarra, KB Fonseca, S Guerreiro, R Maia, F Lourenço, MB Evangelista, JL Santos, C Salgado, F Munarin, MA Barbosa, CC Barrias and PL Granja. Bone tissue engineering. Spring Biointerfaces Pedro L. Granja n 31/41
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Lab Meeting. Porto: July 5, 2011. Maia FR, Fonseca KB, Cruz FA, Granja PL. Barrias CC. Modulation of 3D-­‐cultured hMSC behaviour through changes in matrix physicochemical properties. Tissue Engineering and Regenerative Medicine International Society, TERMIS 2011. Granada, Spain: June 7-­‐10, 2011. Oliveira C, Corso G, Cunha C, Leite M, Figueiredo J, Caldeira J, Paredes J, Granja PL, Oliveira MJ, Figueiredo C, Carneiro F, Roviello F, Seruca R. Gastric cancer -­‐ Molecular markers as tools to improve diagnosis, prognostic and therapeutic selection. Update of Pathological Anathomy and Clinical Relapse. Sorrento: May 27-­‐29, 2011. Fonseca KB, Bidarra SJ, Oliveira MJ, Granja PL, Barrias CC. Alginate-­‐based hydrogels susceptible to proteolytic degradation. VI International Materials Symposium Materiais 2011-­‐XV Meeting of SPM (Portuguese Materials Society). Guimarães: April 18-­‐20, 2011. Fonseca KB, Cruz FA, Lourenço AF, Granja PL, Barrias CC. Injectable Alginate Polymers for Bone Tissue Regeneration: Physico-­‐Chemical Properties and In vitro Mesenchymal Stem Cell Response. GRIBOI 2011 -­‐ 21st Interdisciplinary Research Conference on Injectable Osteoarticular Biomaterials and Bone Augmentation Procedures. Boston, USA: April 5-­‐7, 2011 Fonseca KB, Bidarra SJ, Oliveira MJ, Granja PL, Barrias CC. Alginate Hydrogels Functionalized With a Protease-­‐Sensitive Motif as Dynamic Microenvironments for 3D Cultured Stem Cells. 23nd European Conference on Biomaterials. Tampere, Finland: September 11-­‐15, 2010. Munarin F, Grellier MA, Guerreiro SG, Petrini P, Tanzi MC, Barbosa MA, Granja PL. Pectin microspheres promote preosteoblast 3-­‐dimensional growth. 23nd European Conference on Biomaterials. Tampere, Finland: September 11-­‐15, 2010. Lopes JL, Dourado F, Machado JM, Granja PL, Gama FM, Gomes JR. Tribological Properties of Bacterial Cellulose in Reciprocating Sliding Against Bovine Articular Cartilage. 14th Nordic Symposium on Tribology (Nordtrib) 2010. Storforsen, Sweden: June 8-­‐11, 2010. Pandita D, Santos JL, Rodrigues J, Pego AP, Granja PL, Tomás H. Gene Delivery into MSCs: a Biomimetic Approach using RGD Nanoclusters based on PAMAM Dendrimers. 5th European Symposium on Biopolymers. Madeira; Portugal: November 18-­‐20, 2009. Munarin F, Petrini P, Farè S, Barbosa MA, Tanzi MC, Granja PL. Electrostatically extruded pectin microspheres and their physico-­‐chemical properties. 2nd Chinese-­‐European Symposium on Biomaterials in Regenerative Medicine. Barcelona, Spain: November 17-­‐20, 2009. Grellier M, Bareille R, Bourget C, Bidarra SJ, Ferreira-­‐Tojais N, Fricain JC, Renard M, Barbosa M, Granja PL, Amédée J. Osteo-­‐endothelial cell communication for bone tissue engineering. 2nd Chinese-­‐European Symposium on Biomaterials in Regenerative Medicine. Barcelona, Spain: November 17-­‐20, 2009. Cunha CB, Oliveira C, Gomes B, Suriano G, Xiaogang W, Grellier M, Huntsman D, Carneiro F, Granja PL, Seruca R. V Meeting on RNA Research in Portugal. De novo expression of cd44 variants in sporadic and hereditary gastric cancer. November 5-­‐6, 2009. Lisbon. Bidarra SJ, Barrias CC, Barbosa MA, Soares R, Granja PL. Exploring the endothelial -­‐ mesenchymal stem cells relationship in a RGD modified alginate matrix – a strategy for bone regeneration. 22nd European Conference on Biomaterials. Lausanne, Switzerland: September 7-­‐
11, 2009. Guerreiro S, Barbosa MA, Soares R, Granja PL. Modulation of cells behavior when immobilized in RGD-­‐alginate. 22nd European Conference on Biomaterials. Lausanne, Switzerland: September 7-­‐11, 2009. Grellier M, Granja PL, Fricain J-­‐C, Bidarra SJ, Renard M, Bareille R, Bourget C, Amédée J, Barbosa MA. Co-­‐immobilization of Human Osteoprogenitors and Endothelial Cells within Alginate Matrix for Bone Tissue Engineering. 22nd European Conference on Biomaterials. Lausanne, Switzerland: September 7-­‐11, 2009. Cunha C, Oliveira C, Gomes B, Suriano G, Xiaogang W, Grellier M, Huntsman D, Carneiro F, Pedro L. Granja n 32/41
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Granja PL, Seruca R. De novo expression of CD44 variants in sporadic and hereditary gastric cancer. V Meeting on RNA research in Portugal. Carcavelos, Portugal: Nov 5-­‐6, 2009. Lopes JL, Rybolova P, Granja PL, Gomes JR. Tribological response of pHema-­‐based hydrogels against bovine cartilage. IBERTRIB 2009 – V Iberian Congress on Tribology. Coimbra, Portugal: June 17-­‐19, 2009. Cunha C, Oliveira C, Suriano G, Seruca R, Granja PL. CD44 is a good molecule to target gastric malignant cells. Nanomedicine 2009 -­‐ 2nd European Summer School in Nanomedicine. Jun 12-­‐
16, 2009. Lisbon, Portugal. Monteiro FJ, Estêvão I, Granja PL, Fonseca C, Pina MF, Lamghari M, Barbosa MA. Physico-­‐
chemical and histological analyses of retrieved hip implants in Portugal. 2nd Workshop on Biotribology. Guimarães. May 25-­‐27, 2009. Santos JL, Pandita D, Rodrigues J, Pego AP, Granja PL, Tomás H. Dendrimers surface engineering for improved cellular uptake and gene delivery to mesenchymal stem cells. 4th Annual International Meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-­‐TC). Lisbon, Portugal: April 29-­‐30, 2009. Grellier M, Granja PL, Fricain JC, Bidarra SJ, Bareille R, Bourget C, Barbosa MA and Amédée J, Osteo-­‐endothelial co-­‐immobilization within alginate microspheres: bone tissue engineering application. Journées Françaises de Biologie des Tissus Minéralisées (JFBTM), Nice, France: March 19-­‐21, 2009. Salgado CL, Silva PB, Solomão Z, Granja PL, Sanchez EMS, Zavaglia CAC. Comparative study of poly(ε-­‐caprolactone) and β-­‐tricalcium phosphate composite porous membranes. Bioceramics 21 – 21st International Symposium of Ceramics in Medicine. Búzios, Brazil: October 21-­‐24, 2008. Bidarra SJ, Barrias CC, Barbosa MA, Soares R, Granja PL. RGD-­‐grafted alginate microspheres as carriers for human mesenchymal stem cells. SIBB BioBCN 2008. 3rd edition of the Iberian Biomaterials Congress and the XXXI Symposium of the Sociedad Ibérica de Biomecánica y Biomateriales. Barcelona, Spain: September 17-­‐19, 2008. Grellier M, Bidarra S, Bareille R, Fricain JC, Granja PL, Barbosa MA, Amédée J. Encapsulation of Osteoprogenitor and Endothelial cell Co-­‐cultures for tissue Engineering. International Society for Applied Cardiovascular Biology (ISACB) 11th Biennial Meeting. Bordeaux, France: September 17-­‐20, 2008. Bidarra SJ, Barrias CC, Barbosa MA, Soares R, Granja PL. Upregulation of mesenchymal stem cells differentiation and proliferation in coculture with endothelial cells. Tissue Engineering and Regenerative Medicine International Society (TERMIS)-­‐EU 2008 Annual Meeting. Porto: June 22-­‐26, 2008; Tissue Engineering A 2008;14:p.793. Granja PL, Estêvão I, Fonseca C, Monteiro FJ, Lamghari M, Pina MF, Barbosa MA. Analyses of retrieved hip implants in Portugal. Core Laboratories for the Improvement of Medical Devices In Clinical Practice from the Failure of the Explanted Prostheses Analysis (FEPA)-­‐COST 537 Project. Working Group 3 -­‐ Orthopaedics Training School. Porto: June 05-­‐07, 2008. Santos L, Oramas E, Pêgo A, Granja PL, Tomás H. In Vitro osteoblastic differentiation of MSCs using PAMAM Dendrimers as delivery vectors for the hBMP-­‐2 gene. 8th World Biomaterials Congress. Amsterdam, The Netherlands: May 28-­‐June 01, 2008. Bidarra SJ, Barrias CC, Mooney DJ, Barbosa MA, Soares R, Granja PL. Immobilization of mesenchymal stem cells within RGD-­‐grafted alginate. 8th World Biomaterials Congress. Amsterdam, The Netherlands: May 28-­‐June 01, 2008. Grellier M, Bidarra SJ, Bareille R, Fricain JC, Granja PL, Barbosa MA, Amédée J. Encapsulation of osteoprogenitor and endothelial cell co-­‐cultures for bone tissue engineering application. ECM IX: Musculoskeletal Trauma, 50 Years of AO Research. Davos, Switzerland: June 15-­‐18, 2008. Santos JL, Oramas E, Pego AP, Granja PL, Tomás H. Osteogenic differentiation of mesenchymal Pedro L. Granja n 33/41
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stem cells through gene delivery. 3rd International Meeting of the Portuguese Society for Stem Cells and Cellular Therapy -­‐ From Molecular Mechanisms to Therapeutical applications. Faro: April 23-­‐24, 2008. Cunha C, Granja PL, Suriano G, Oliveira C, Seruca R. Targeting nanoparticles for diagnosis of gastric cancer. NANOSpain 2008 Conference. Apr 14-­‐18, 2008, Braga, Portugal. Santos JL, Oramas E, Pego AP, Granja PL, Tomás H. In vitro osteogenesis via gene delivery. 5th Marie Curie Cutting-­‐Edge Conference. Funchal, Madeira: April 14-­‐18, 2008. Cunha C, Oliveira C, Seruca R, Granja PL, Suriano G. CD44 in gastric cancer cell lines. 11th Annual Meeting of the Human Genetics Portuguese Society (SPGH). Porto: November 15-­‐17, 2007. Chollet C, Lazare S, Granja PL, Durrieu M-­‐C. UV excimer laser ablation of RGD peptides grafted onto poly(ethylene terephtalate): Impact on cell attachment. 21st European Conference on Biomaterials. Brighton, UK: September 9-­‐13, 2007. Grellier M, Bareille R, Bourget C, Ferreira Tojais N, Granja PL, Barbosa MA, Amédée J. Cell Cooperation between human Osteoprogenitor and Endothelial Cells for Bone Tissue Engineering. Tissue Engineering and Regenerative Medecine International Society (TERMIS)-­‐EU Chapter Meeting. London, England: September 4-­‐7, 2007. Grellier M, Bareille R, Bourget C, Ferreira Tojais N, Granja PL, Barbosa MA, Amédée J. Cell cooperation between osteoprogenitor and endothelial cells: Its function on bone tissue engineering. ECM VIII Bone Tissue Engineering. Davos, Switzerland: June 25-­‐28, 2007. European Cells and Materials Vol. 14. Suppl. 1, 2007 (page 33). Evangelista MB, Granja PL, Barbosa MA, Sampaio P, Kong HJ, Hsiong S, Mooney DJ. Immobilization of bone cells within microspheres of a synthetic extracelular matrix capable of regulating cell function. 6th International Symposium on Frontiers in Biomedical Polymers (2005). Granada, Spain: June 16-­‐19, 2005. Granja PL. Biomaterials Network (Biomat.net). Encontro Nacional de Ciência e Tecnologia 2004 (ENCT04). Aveiro: October 22-­‐23, 2004. Evangelista MB, Ferreira L, Granja PL, Barbosa MA. Composite hydrogels as intervertebral disc substitutes. II Evaluation of interface between PET fibers and pHEMA hydrogels by pull-­‐out test. BioÉvora 2004 – 2nd Iberian Congress on Biomaterials. Évora: September 9-­‐11, 2004. Rodrigues SN, Ferreira L, Granja PL, Barbosa MA. Composite hydrogels as intervertebral disc substitutes: Wettability studies and mechanical characterization of pHEMA hydrogels reinforced with ozonated bundles of PET fibers. BioÉvora 2004 – 2nd Iberian Congress on Biomaterials. Évora: September 9-­‐11, 2004. Silva AIN, Amaral IF, Barrias CC, Granja PL, Borges JP, Barbosa MA. Preparation and characterization of injectable chitosan-­‐hydroxyapatite microspheres. 16th International Symposium on Ceramics in Medicine -­‐ Bioceramics 16. Porto: November 6-­‐9, 2003. Amaral IF, Granja PL, Barbosa MA. In vitro mineralisation of chitosan membranes carrying phosphate functionalities. 16th International Symposium on Ceramics in Medicine -­‐ Bioceramics 16. Porto: November 6-­‐9, 2003. Granja PL, Pouységu L, Bareille R, De Jéso B, Baquey C, Barbosa MA. Comparison of chemical and cellular mechanisms to induce mineralization of natural polymers. International Conference on Advances in Biomaterials for Reconstructive Medicine. Capri, Italy: June 9-­‐14, 2002. Granja PL, De Jéso B, Bareille R, Baquey C, Barbosa MA. In vitro mineralization of regenerated cellulose hydrogels in human osteoprogenitor cells. 16th European Conference on Biomaterials. London, UK: September 12-­‐14, 2001. Fricain JC, Granja PL, Barbosa MA, De Jéso B, Bruneteau P, Baquey C. Bone integration study of phosphorylated cellulose implanted in the femoral condyle of rabbit. 16th European Pedro L. Granja n 34/41
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Conference on Biomaterials. London, UK: September 12-­‐14, 2001. Amaral IF, Granja PL, Saramago B, Barbosa MA. Surface chemistry and cytotoxicity of phosphorylated chitosan membranes. 16th European Conference on Biomaterials. London, UK: September 12-­‐14, 2001. Barrias CC, Granja PL, Lacerda L, Sá Miranda C, Barbosa MA. Bone-­‐targeted delivery of glucocerobrosidase for the treatment of osseous lesions in Gaucher disease. 16th European Conference on Biomaterials. London, UK: September 12-­‐14, 2001. Amaral IF, Granja PL, Melo LV, Saramago B, Barbosa MA. Chemical modification of chitosan membranes via phosphorylation. 3rd International Symposium on Chitin Enzymology and 4th Conference of the European Chitin Society. Ancona, Italy: May 6-­‐10, 2001. Granja PL, De Jéso B, Bareille R, Rouais F, Baquey C, Barbosa MA. Mineralization of regenerated cellulose hydrogels induced by human osteoprogenitor cells. Materiais’2001 -­‐ 1st International Materials Symposium. Coimbra: April 9-­‐11, 2001. p. 191. Fricain JC, Granja PL, Barthe N, Barrias C, De Jéso B, Barbosa MA, Baquey C. Etude de l’integration osseuse dans le condyle femorale de lapins d’implants de cellulose et de cellulose phosphatee, 2nd International Symposium on Advanced Biomaterials (ISAB) and 7th International Academy of Shape Memory Material for Medical Use (I~ASMU). Montréal, Canada: June 28 -­‐ July 1, 2000. Granja PL, Ribeiro CC, Rouais F, Pouységu L, De Jéso B, Baquey C, Barbosa MA. Influence of the pre-­‐incubation in calcium on the mineralization of unmodified and phosphorylated cellulose. Biomineralization of Implant Materials. Lisbon: June 15, 2000. Granja PL, Ribeiro CC, Rouais F, Pouységu L, De Jéso B, Baquey C, Barbosa MA. Influence of the phosphorylation degree on the mineralization of cellulose phosphate hydrogels. BioEng’00 -­‐ 5th Portuguese Conference on Biomedical Engineering. Coimbra: May 26-­‐27, 2000. p. 43. Amaral I, Granja PL, Melo LV, Barbosa MA. Phosphorylation of chitosan membranes. BioEng’00 -­‐ 5th Portuguese Conference on Biomedical Engineering. Coimbra: May 26-­‐27, 2000. p. 59. Fonseca AP, Granja PL, Nogueira JA, Barbosa MA. Adhesion of staphylococcus epidermidis and transposon mutant strains to cellulose diacetate. BioEng’00 -­‐ 5th Portuguese Conference on Biomedical Engineering. Coimbra: May 26-­‐27, 2000. p. 14. Granja PL, Rouais F, Pouységu L, De Jéso B, Baquey C, Barbosa MA. In Vitro Mineralization of Regenerated Cellulose Hydrogels. 6th World Biomaterials Congress Transactions. Society for Biomaterials. Hawaii, USA: May 15-­‐20, 2000. p. 116. Granja PL, Bareille R, Rouais F, De Jéso B, Barbosa MA, Baquey C. Influence of the phosphorylation degree on the attachment of human osteoprogenitor cells to cellulose phosphates. 15th European Conference on Biomaterials. Bordeaux, France: September 8-­‐12, 1999. Pereira JP, Granja PL, De Jéso B, Baquey C, Barbosa MA. Influence of the incorporation of Ca, Na, Mg and Sr on the mineralization of phosphorylated cellulose. 15th European Conference on Biomaterials. Bordeaux, France: September 8-­‐12, 1999. Fonseca AP, Granja PL, Nogueira A, Baquey C, De Jéso B, Barbosa MA. Adhesion of S. epidermidis to cellulose derivatives comparing to commercial polymeric biomaterials. 15th European Conference on Biomaterials. Bordeaux, France: September 8-­‐12, 1999. Granja PL, Pouységu L, De Jéso B, Baquey C, Barbosa MA. Cellulose Phosphates as Biomaterials. Mineralization Studies. 13th European Conference on Biomaterials. Gothenburg, Sweden: September 4-­‐7, 1997. p. 125. Granja PL, Pouységu L, Pétraud M, De Jéso B, Baquey C, Barbosa MA. Cellulose Phosphates as Biomaterials. A Nuclear Magnetic Resonance Investigation. 2nd Symposium on Frontiers in Biomedical Polymers -­‐ Biomaterials and Drug Delivery Systems. Eilat, Israel: April 6-­‐9, 1997. p. 41. Pedro L. Granja n 35/41
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Granja PL, Pouységu L, Bareille R, Poustis J, Barbosa MA, Baquey C, De Jéso B. Biomatériaux à base de phosphate de cellulose: Hemi-­‐synthèse et caractérisation. Biomatériaux et Suppléance Fonctionelle. Bordeaux, France: December 18, 1996. p. 28-­‐30. Reis R, Granja PL, Cunha AM. Impact behaviour of UHMWPE/HA composites for orthopaedic applications. 1st Symposium on Frontiers in Biomedical Polymers -­‐ Biomaterials and Drug Delivery Systems. Portofino, Italy: June 6-­‐9, 1995. •
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POSTER COMMUNICATIONS Costa-­‐Almeida R, Gomez-­‐Lazaro M, Soares R, Guerreiro SG, Granja PL. Interactions between dermal fibroblasts and endothelial cells in vascularization for tissue engineering. Tissue Engineering and regenerative Medicine International Society (TERMIS) -­‐ EU Meeting 2014. Genova, Italy: Jun 10-­‐13, 2014. Branco da Cunha C, Chaudhuri O, Granja PL, Mooney DJ. Culture dimensionality controls CD44 expression. Keystone Symposia on Molecular and Cellular Biology “Engineering Cell Fate and Function”. Lake Tahoe, CA, USA: Apr 6-­‐11, 2014. Sousa A, Neves SC, Bártolo P, Granja PL. Pectin hydrogels for dermal wound healing. 4th BSRT PhD Symposium "Regeneration is Communication: Fireside Chats between Cells & Matrices”. Germany, Berlin: Dec 4-­‐6, 2013. Sousa A, Gomes DB, Neves SC, Barrias CC, Granja PL. Pectin hydrogels for skin regeneration and repair. 4th BSRT PhD Symposium "Regeneration is Communication: Fireside Chats between Cells & Matrices”. Germany, Berlin: Dec 4-­‐6, 2013. Sousa A, Gomes DB, Neves SC, Barrias CC, Granja PL. Pectin hydrogels for skin regeneration and repair. 4th BSRT PhD Symposium "Regeneration is Communication: Fireside Chats between Cells & Matrices”. Berlin, Germany: Dec 4-­‐6, 2013. Sousa A, Neves SC, Bártolo P, Barrias CC, Granja PL. Pectin hydrogels for dermal wound healing. 4th BSRT PhD Symposium "Regeneration is Communication: Fireside Chats between Cells & Matrices”. Berlin, Germany: Dec 4-­‐6, 2013. Costa-­‐Almeida R, Gomez-­‐Lázaro M, Granja PL, Soares R, Guerreiro SG. Human dermal fibroblasts and endothelial cells: A co-­‐culture approach to promote vascularization in tissue engineering. #5 Symposium on Bioengineering. Porto: Nov 15-­‐16, 2013. Maia FR, Rodrigues G, Granja PL, Barrias CC. Three-­‐dimensional culture of mesenchymal stem cells in deformable low-­‐stiffness matrices. 8th Annual International Meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-­‐TC), Faro: May 9-­‐10, 2013. Costa-­‐Almeida R, Guerreiro SG, Granja PL, Soares R. Crosstalk between outgrowth endothelial cells and fibroblasts in vascularization. IJUP’13 – 6º Meetings of Young Researchers of University of Porto. Porto: Feb 13-­‐15, 2013. Guerreiro SG, Unger RE, Sartoris A, Martins MJ, Barbosa MA, Soares R, Granja PL, Kirkpatrick CJ. Crosstalk between fibroblasts and endothelial cells promotes angiogenesis in vitro: putative role of alkaline phosphatase. 3rd TERMIS World Congress 2012 “Tissue Engineering and Regenerative Medicine”. Vienna, Austria: September 5-­‐8, 2012. Fonseca KB, Granja PL, Barrias CC. Physico-­‐chemical and enzymatic properties of PVGLIG and PVGLIG-­‐alginate hydrogels. 3rd TERMIS World Congress 2012 “Tissue Engineering and Regenerative Medicine”. Vienna, Austria: September 5-­‐8, 2012. Bidarra SJ, Fonseca KB, Granja PL, Barrias CC. Learning from the cell-­‐matrix crosstalk to improve a cell delivery system based on RGD-­‐modified alginate. 3rd TERMIS World Congress “Tissue Engineering and Regenerative Medicine”. Vienna, Austria: September 5-­‐8, 2012. Branco da Cunha C, Granja PL, Mooney DJ. Substrate dimensionality controls the expression of CD44 receptors. Gordon Research Conference: Signal Transduction by Engineered Extracellular Pedro L. Granja n 36/41
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Matrices. Biddeford, ME, USA: Jul 8-­‐13, 2012. Guerreiro S, Soares R, Barbosa MA, Unger RE, Kirpatrick CJ, Granja PL. The crosstalk between endothelial cells and fibroblasts in tissue vascularization. 9th World Biomaterials Congress. Chengdu, China: June 1-­‐5, 2012. Bidarra SJ, Barrias CC, Fonseca KB, Barbosa MA, Soares R, Granja PL. Angiogenic potential of cell-­‐loaded injectable RGD-­‐modified alginate. 9th World Biomaterials Congress (WBC). Chengdu, China: June 1-­‐5, 2012. Fonseca KB, Bidarra SJ, Oliveira MJ, Granja PL, Barrias CC. Matrizes biofuncionais para cultura em 3D e diferenciação osteogénica de células estaminais mesenquimatosas. XXXI National Congress of Orthopedics and Traumatology. Estoril: October 19-­‐21, 2011. Guerreiro S, Negrão R, Oliveira MJ, Barbosa MA, Soares R, Granja PL. Modulation of angiogenesis by fibroblasts in tissue regeneration. XXXVIII Congress of the European Society for Artificial Organs (ESAO 2011) and IV Biennial Congress of the International Federation on Artificial Organs (IFAO 2011). Porto: October 9-­‐12, 2011. Maia FR, Lourenço AF, Fonseca K, Figueiredo LR, Granja PL, Barrias CC. An overview on the use of alginate hydrogel matrices as versatile 3D cellular microenvironments. 1st Advanced Summer School-­‐Interrogations at the Biointerface: Cancer/Regeneration Interface. Porto, Portugal: June 20-­‐24, 2011. Bidarra SJ, Barrias CC, Fonseca KB, Barbosa MA, Soares R, Granja PL. Injectable in situ crosslinkable alginate matrix for endothelial cells delivery 1st Advanced Summer School-­‐
Interrogations at the Biointerface: Cancer/Regeneration Interface. Porto, Portugal: June 20-­‐24, 2011. Lourenço AF, Gonçalves R, Granja PL, Barrias CC. 1st Advanced Summer School-­‐Interrogations at the Biointerface: Cancer/Regeneration Interface. Porto, Portugal: June 20-­‐24, 2011. Cunha CB, Oliveira C, Seruca R, Mooney DJ, Granja PL. CD44 splicing patterns in 3D cultures: new avenues for understanding gastric cancer biology. 2nd I3S Scientific Retreat “Together in Science”. Póvoa de Varzim, Portugal: May 5-­‐6, 2011. Fonseca KB, Maia FR, Lourenço AF, Cruz FA, Granja PL, Barrias CC. Alginate hydrogels as versatile artificial microenvironments for 3D cell culture: An overview. 2nd I3S Scientific Retreat “Together in Science”. Póvoa de Varzim, Portugal: May 5-­‐6, 2011. Maia FR, Fonseca KB, Cruz FA, Granja PL, Barrias CC. Effect of matrix physicochemical properties on 3D-­‐cultured mesenchymal stem cells. I3S Scientific Retreat “Together in Science”. Póvoa de Varzim, Portugal: May 5-­‐6, 2011. Lopes JL, Castanheira L, Dourado F, Machado JM, Granja PL, Gama FM, Gomes JR. Friction and wear behaviour of bacterial cellulose against articular cartilage. 18th International Conference on Wear of Materials. Philadelphia, USA: April 3-­‐7, 2011. Lopes JL, Dourado F, Machado JM, Castanheira L, Granja PL, Gama FM, Gomes JR. Tribological Performance of Bacterial Cellulose-­‐Articular Cartilage Systems: Influence of Loading Conditions in Simulated Synovial Fluid. TRIBOBR 2010 – First International Brazilian Conference on Tribology. Rio de Janeiro, Brazil: Nov 24-­‐26, 2010. Guerreiro S, Unger RE, Sartoris A, Oliveira MJ, Barbosa MA, Soares R, Granja PL, Kirkpatrick CJ. Crosstalk between endothelial cells and fibroblasts in modulating the healing response. 23nd European Conference on Biomaterials. Tampere, Finland: September 11-­‐15, 2010. Munarin F, Guerreiro S, Grellier M, Petrini P, Tanzi MC, Barbosa MA, Granja PL. Pectin microspheres as new injectable systems for bone tissue regeneration. Secondo Congresso Nazionale di Bioingegneria -­‐ Congresso GNB2010. Turin, Italy: July 8-­‐10, 2010. Guerreiro S, Negrão R, Oliveira M, Barbosa MA, Soares R, Granja PL. Fibroblasts influence angiogenesis in tissue regeneration. Tissue Engineering and Regenerative Medicine International Society (TERMIS)–EU. Galway, Ireland: June 13-­‐17, 2010. Pedro L. Granja n 37/41
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Cunha C, Oliveira C, Gomes B, Suriano G, Xiaogang W, Grellier M, Huntsman D, Carneiro F, Granja PL, Seruca R. De novo expression of cd44 variants in sporadic and hereditary gastric cancer. 13th Annual Meeting of Portuguese Society for Human Genetics (13ª Reunião Anual da Sociedade Portuguesa Genética Humana, SPGH). Porto, Portugal: November 19-­‐21, 2009. Pina MF, Lamghari M, Barbosa MA, Monteiro FJ, Granja PL, Fonseca C. The implementation of a register for explanted prosthesis. XXIX Congresso Nacional de Ortopedia e Traumatologia (SPOT 2009). Porto, Portugal: October 28-­‐30, 2009. Fonseca KB, Bidarra SJ, Granja PL, Barrias CC. Design of Alginate Hydrogels Susceptible to Proteolytic Degradation. 2nd TERMIS (Tissue Engineering and Regenerative Medicine International Society) World Congress, in conjunction with 2009 Seoul Stem Cell Symposium. Seoul, Republic of Korea: Aug 31 -­‐ Sep 3, 2009. Cunha C, Suriano G, Oliveira C, Seruca R, Granja PL. CD44v6 as a key-­‐molecule to target gastric cancer progression. 10th Advanced Summer Course in Cell-­‐Materials Interactions: Self-­‐
Assembly – From Nature to Clinics. Porto. June 22-­‐26, 2009. Bidarra SJ, Barrias CC, Barbosa MA, Soares R, Granja PL. Endothelial and mesenchymal stem cells as partakers for a bone renewal approach. 10th Advanced Summer Course in Cell-­‐
Materials Interactions: Self-­‐Assembly – From Nature to Clinics. Porto. June 22-­‐26, 2009. Guerreiro S, Wu G, Granja PL. Modulation of cells behaviour by indirect contact cocultures. 10th Advanced Summer Course in Cell-­‐Materials Interactions: Self-­‐Assembly – From Nature to Clinics. Porto. June 22-­‐26, 2009. Fonseca KB, Bidarra Sj, Granja PL, Barrias CC. 3D cell cultures within alginate hydrogels susceptible to proteolytic degradation. 10th Advanced Summer Course in Cell-­‐Materials Interactions: Self-­‐Assembly – From Nature to Clinics. Porto. June 22-­‐26, 2009. Munarin F, Tanzi MC, Barbosa MA, Granja PL. Preparation and characterization of pectin-­‐based microspheres. 10th Advanced Summer Course in Cell-­‐Materials Interactions: Self-­‐Assembly – From Nature to Clinics. Porto. June 22-­‐26, 2009. Antunes JI, Pereira AC, Ferreira da Silva F, Gonçalves R, Amaral IF, Pêgo AP, Granja PL, Barbosa MA. Ch-­‐based polyelectrolyte complexes for tissue engineering applications. 10th Advanced Summer Course in Cell-­‐Materials Interactions: Self-­‐Assembly – From Nature to Clinics. Porto. June 22-­‐26, 2009. Santos JL, Pandita D, Rodrigues J, Pego AP, Granja PL, Balian G, Tomás H. Receptor-­‐Mediated Gene Delivery in Mesenchymal Stem Cells by PAMAM Dendrimers conjugated with Osteotropic Peptides. 10th Advanced Summer Course in Cell-­‐Materials Interactions: Self-­‐
Assembly – From Nature to Clinics. Porto. June 22-­‐26, 2009. Cunha C, Suriano G, Oliveira C, Seruca R, Granja PL. Cancer Nanotechnology: Looking for the key-­‐molecule to target gastric cancer cells. 2nd European Summer School In Nanomedicine, Lisbon. June 12-­‐16, 2009. Lopes JL, Rybolova P, Abreu CS, Granja PL, Gomes JR. In vitro reciprocating sliding for the simulation of friction and wear in articular cartilage. 2nd Workshop on Biotribology. Guimarães. May 25-­‐27, 2009. Lopes JL, Rybolova P, Granja PL, Gomes JR. Preparation and tribological characterisation of hydrogels for biomedical applications. 2nd Workshop on Biotribology. Guimarães. May 25-­‐27, 2009. Lopes JL, Rybolova P, Granja PL, Gomes JR. Friction behaviour of PHEMA/PMMA hydrogels for articular cartilage. Materiais 2009 -­‐ 5th International Materials Symposium (XIV Meeting of the Portuguese Materials Society -­‐ SPM). Lisbon, Portugal. April 5-­‐8, 2009. Guerreiro S, Soares R, Granja PL. Effect of VEGF and bFGF on human endothelial cells behaviour within RGD-­‐grafted alginate. VI Encontro do Fórum Internacional de Investigadores Portugueses (FIIP 2009) – Brain, Life and Culture. Lisbon, Portugal. December 18-­‐20, 2008. Pedro L. Granja n 38/41
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Guerreiro S, Soares R, Granja PL. Modulation of endothelial cells behaviour within functionalized alginate. Lectures on Modeling Cancer Growth and Treatments. Estoril, Portugal. December 8-­‐9, 2008. Salgado C, Sanchez E, Zavaglia C, Granja PL. Injectable Polymeric Matrices for Bone Tissue Engineering. 8th World Biomaterials Congress. Amsterdam, The Netherlands: May 28-­‐June 06, 2008. Evangelista MB, Silva EA, Kim E-­‐S, Granja PL, Mooney DJ. Influence of different human endothelial cell populations on osteoprogenitor differentiation. 8th World Biomaterials Congress. Amsterdam, The Netherlands: May 28-­‐June 06, 2008. Guerreiro S, Bidarra SJ, Evangelista MB, Barrias CC, Barbosa MA, Soares R, Granja PL. Immobilization of human endothelial cells within RGD-­‐grafted alginate. 8th World Biomaterials Congress. Amsterdam, The Netherlands: May 28-­‐June 06, 2008. Grellier M, Bidarra SJ, Bareille R, Granja PL, Barbosa MA, Amédée J. Cell Encapsulation for Vascularized Bone Tissue Engineering. 8th World Biomaterials Congress. Amsterdam, The Netherlands: May 28-­‐June 06, 2008. Cunha C, Granja PL, Suriano G, Oliveira C, Seruca R. Targeting nanoprobes for early invasive cancer cells using Hereditary Diffuse Gastric Cancer (HDGC) as a model. NanoSpain 2008. Braga: April 14-­‐18, 2008. Santos JL, Oramas E, Pego AP, Granja PL, Tomás H. PAMAM dendrimers used as vectors for gene delivery into Mesenchymal Stem Cells. NanoSpain 2008. Braga: April 14-­‐18, 2008. Grellier M, Bidarra SJ, Bareille R, Fricain JC, Amédée J, Granja PL, Barbosa MA. Encapsulation of Osteoprogenitor and Endothelial cell Co-­‐cultures for Bone Tissue Engineering application. International Bone and Mineral Society (IBMS). Davos, Switzerland: March 9-­‐14, 2008. Bidarra SJ, Barrias CC, Barbosa MA, Soares R, Granja PL. Gene expression of osteogenic markers of human mesenchymal stem cells in a 3D environment. First International Conference on Stem Cell Engineering. Coronado Island, California, USA: January 20-­‐23, 2008. Evangelista MB, Hsiong SX, Fernandes R, Sampaio P, Kong HJ, Barrias CC, Salema R, Barbosa MA, Mooney DJ, Granja PL. Upregulation of bone cells differentiation immobilized within 3D synthethic extracellular matrix. BMES (Biomedical Engineering Society) 2007 Annual Fall Meeting. Los Angeles, California, USA: September 26-­‐29, 2007. Grellier M, Bareille R, Bourget C, Granja PL, Barbosa MA, Amédée J. Cell Cooperation between Human OsteoProgenitor Cells and Endothelial Cells in Tissue Engineering. American Society of Bone and Mineral Research (ASBMR) 29th Annual Meeting. Honolulu, Hawaii, USA: September 14-­‐19, 2007. Santos JL, Oliveira H, Oramas EG, Pego AP, Granja PL, Tomás H. Gene Therapy Platform For Bone Regeneration Using Dendrimers and Osteogenic Plasmids Systems. Gordon research Conference on Biomaterials: Biocompatibility / Tissue Engineering. Plymouth, New Hampshire, USA: July 22-­‐27, 2007 Bidarra SJ, Barrias CC, Barbosa MA, Soares R, Granja PL. Immobilization of human mesenchymal stem cells. ECM VIII Bone Tissue Engineering. Davos, Switzerland: June 25-­‐28, 2007. European Cells and Materials Vol. 14. Suppl. 1, 2007 (page 52). Bidarra SJ, Barrias CC, Barbosa MA, Soares R, Granja PL. RGD-­‐grafted alginate as a biomaterial for hMSC immobilization. 8th Advanced Summer Course in Cell-­‐Materials Interactions. Porto: June 18-­‐22, 2007. Guerreiro S, Bidarra SJ, Barrias CC, Barbosa MA, Soares R, Granja PL. Human endothelial cells immobilization within alginate. 8th Advanced Summer Course in Cell-­‐Materials Interactions. Porto: June 18-­‐22, 2007. Santos JL, Oramas EG, Pego AP, Granja PL, Tomás H. Polyamidoamine dendrimer vectors for gene delivery: Physicochemical characterization and transfection efficiency evaluation. 8th Pedro L. Granja n 39/41
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Advanced Summer Course in Cell-­‐Materials Interactions. Porto: June 18-­‐22, 2007. Santos JL, Oramas EG, Pego AP, Granja PL, Tomás H. In vitro gene delivery studies using polyamidoamine dendrimers: physicochemical characterization of dendriplexes and transfection efficiency evaluation. 3rd Marie Curie Cutting Edge Conference -­‐ Biomineralisation of polymeric materials, bioactive biomaterials and biomimetic methodologies. Funchal, Madeira: June 4-­‐8, 2007. Bidarra SJ, Soares R, Granja PL. Immobilization of endothelial cells. Bioencapsulation. COST Action 865. Lisbon: April 26-­‐27, 2007. Extremina CI, Granja PL, Freitas da Fonseca A, Fonseca AP. Adhesion of Staphylococcus epidermidis to a modified cellulose triacetate membrane. 17th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) and 25th International Congress of Chemotherapy (ICC). Munich, Germany: March 31-­‐April 3, 2007. Santos JL, Granja PL, Tomás H. In vitro evaluation of gene delivery in bone marrow stromal cells by polyamidoamine dendrimers. 14th Annual Congress of the European Society of Gene Therapy (ESGT). Athens, Greece: November 9-­‐12, 2006. Barrias CC, Martins MCL, Bidarra S, Almeida-­‐Porada G, Barbosa MA, Granja PL. Mixed Self-­‐
Assembled Monolayers as Substrates for the Culture of Human Mesenchymal Stem Cells. 20th European Conference on Biomaterials. Nantes, France: Sep 27 -­‐ Oct 1, 2006 (last minute poster). Coelho A, Oliveira A, Saleiro D, Melo J, Monteiro J, Regadas N, Matos R, Carvalho T, Giesteira B, Ferreira C, Granja PL, Santos J, Barbosa MA. NetImplants: Desenvolvimento de um protótipo de um conteúdo multimédia generalista sobre a utilização de dispositivos médicos implantáveis. Reitoria da Universidade do Porto, Porto: September 20, 2006. Bidarra SJ, Soares R, Granja PL. Study of endothelial cells stimulated with angiogenic factors. 7th Advanced Course in Cell-­‐Material Interactions. Bilbioteca Almeida Garret, Porto: June 19–
23, 2006. Santos JL, Pêgo AP, Oliveira H, Granja PL, Tomás H. PAMAM dendrimers as gene delivery vectors for bone tissue engineering. 7th Advanced Course in Cell-­‐Material Interactions. Bilbioteca Almeida Garret, Porto: June 19–23, 2006. Santos JL, Pêgo AP, Oliveira H, Granja PL, Tomás H. Use of Polyamidoamine Dendrimers as Gene Delivery Vectors for Bone Tissue Engineering. 1st Marie Curie Cutting Edge Conference. Funchal – Madeira: June 1–5, 2006. Santos JL, Granja PL, Tomás H. PAMAM dendrimers as vectors for gene delivery into human primary osteoblastic cells – preliminary cytotoxicity studies. XIII Annual Congress of the European Society for Gene Therapy (ESGT). Prague, Czech Republic: October 29 – November 1, 2005. Granja PL, Pouységu L, Bareille R, De Jéso B, Baquey C, Barbosa MA. Biocompatibility of cellulose phosphates. NATO/ASI on Polymer Based Systems on Tissue Engineering, Replacement and Regeneration. Algarve: October 15-­‐25, 2001. Fricain JC, Granja PL, Barbosa MA, De Jéso B, Bruneteau P, Baquey C. Bone integration study of phosphorylated cellulose implanted in the femoral condyle of rabbit. 16th European Conference on Biomaterials. London, UK: September 12-­‐14, 2001. Amaral I, Granja PL, Melo LV, Barbosa MA. Phosphorylation of chitosan membranes. BioEng’00 -­‐ 5th Portuguese Conference on Biomedical Engineering. Coimbra: May 26-­‐27, 2000. p. 59. Fonseca AP, Granja PL, Nogueira JA, Barbosa MA. Adhesion of staphylococcus epidermidis and transposon mutant strains to cellulose diacetate. BioEng’00 -­‐ 5th Portuguese Conference on Biomedical Engineering. Coimbra: May 26-­‐27, 2000. p. 14. Granja PL, Pouységu L, Bareille R, De Jéso B, Baquey C, Barbosa MA. Bioactivity of cellulose phosphate biomaterials. International Conference on Biopolymer Technology. Coimbra: Pedro L. Granja n 40/41
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September 29 -­‐ October 1, 1999. p. 64. Granja PL, Bareille R, Rouais F, De Jéso B, Barbosa MA, Baquey C. Influence of the phosphorylation degree on the attachment of human osteoprogenitor cells to cellulose phosphates. 15th European Conference on Biomaterials. Bordeaux, France: September 8-­‐12, 1999. Oliveira AL, Granja PL, Reis RL. Effect of surface modifications on the in-­‐vitro mineralization of a biodegradable starch based polymer to be used as a biomaterial. Gordon Research Conference on Biomineralization. New Hampshire, USA: August 1998. Granja PL, Pouységu L, De Jéso B, Baquey C, Barbosa MA. Synthesis and Characterization of Cellulose Phosphates for Biomedical Applications. Gordon Research Conference on Biodegradable Polymers. Barga, Italy: May 4-­‐9, 1997. Granja, P.L., Baquey, C., Pouységu, L., Bareille, R., De Jéso, B., Barbosa, M.A., Cellulose-­‐based Biomaterials for Bone Regeneration: Hemi-­‐synthesis and Characterisation. Polymers in Medicine and Surgery -­‐ PIMS’96. Glasgow, UK: July 1-­‐3, 1996. Granja PL, De Jéso B, Baquey C, Poustis J, Barbosa MA. Biomimetic Natural Materials for Bone Regeneration. Junior-­‐Euromat 96. FEMS Abstracts. Lausanne, Switzerland: August 26-­‐30, 1996. p. 470-­‐471. JANUARY 2015. Pedro L. Granja n 41/41