Scientific Program November 19th to 21st Sheraton WTC São Paulo Av. das Nações Unidas, 12.559 - São Paulo www.ficare.com.br Dear colleagues From November 19th to 21st, FICARE 2015 will be the stage of the largest forum on Rectal Cancer in Latin America which will take place in the WTC Sheraton Hotel in São Paulo, Brazil! Get ready for hot debates among outstanding world specialists in each topic. What is the role for the Robot? What are the latest outcomes in laparoscopic TME and MRI? Is Transanal Endoscopic Microsurgery going to be used for TME? Is the Prone-Jack knife position and extra-levator rectal resection the new standard for all APRs? Neoadjuvant CRT or Chemotherapy alone? Advances in molecular biology and many more updates in rectal cancer will the focus of this year’s edition of FICARE. Check out the incredible line up of international faculty! Their presence will certainly make this a memorable event in Latin America! Get ready for days of intense scientific activity, mixed with pleasant social activities and the opportunity to see friends and international guests again. Welcome and enjoy! Angelita Habr-Gama President 3 3 Thursday, November 19th 08:00 09:00 Registration/Opening Announcements Opening Lecture: 30 Years of TME: What have I Taught and What have I Learned? Bill Heald Presenter: Angelita Habr-Gama Thursday, November 19th 12:30 14:00 Outcomes after TME Moderator: Fábio Campos Cyllindrical Abdominal Perineal Excision Is it really (always) necessary? Anastomic techniques - Is there anything new? Ronan O’Connell Handling the surgical specimen - What has to be in the path report? Mariana Berho Discussion Rodrigo Gomes / Juan Carlos Patron Uriburu / Roberto L. Kaiser Jr 14:45 How Can MRI orient the surgical procedure in rectal cancer? Gina Brown (UK) President: Adriana Diéguez 15:10 Neoadjuvant Corner Moderator: Rob Glynne-Jones Break Exhibit visit Selective Use of Neoadjuvant CRT Bruce Minsky Video Session: Surgical Tips and Avoiding Pitfalls Moderator: Steven Wexner The meaning of high dose in sterilizing rectal cancer Vincenzo Valentini Standarzing Laparoscopic TME Yves Panis Robotic Total Mesorectal Excision: Tips to get started... Martin Weiser High dose rate endorectal brachytherapy: Challenges and opportunities. From neoadjuvant to radical modality for patients with rectal cancer Te Vuong Transanal Total Mesorectal Excision: Where can it go wrong...?? Greg Wynn Contact radiation therapy: long-term data Jean-Pierre Gerard Discussion Antonio Rocco Imperiale / Armando Melani / Fabio Leiro 11:50 Avoiding RT! Chemotherapy alone followed by surgery in rectal cancer Daniel Chang Ultimate Fighting in Rectal Cancer Discussion Patricia Bailão Aguilar / Diana Tait / Sergio Faria Do we really improve TME with the Robot? Moderator: Dieter Hahnloser No Steven Wexner Yes Alessio Pigazzi Discussion Gustavo Rossi / Reinan Ramos / Henrique Fillman 4 4 Discussants: Angelita Habr-Gama Rodrigo Perez Arceu Scanavini / Guilherme Pagin São Julião Ana Gales Yes Torbjorn Holm Discussion Antonio Lacerda / Hélio Moreira Jr. / Guillermo Rosato / Renato Pinho 11:00 No Rob Madoff Complications in Colorectal Surgery What if I end up with a positive resection margin? Yves Panis Bowel Dysfunction after Rectal Cancer Surgery - Is it really bad? Soren Laurberg 10:30 Lunch - Symposium Perioperative Complications in Colorectal Surgery - Interactive Case Discussion (Lunch boxes will be served) November 19 – 12:30h MSD Satellite Symposium Great Debates in Rectal Cancer I Moderator: Bill Heald Clinical cases interactive discussion 16:30 Break 17:00 Assessment of Response to CRT Moderator: Diana Tait Clinical Assessment and the role of biopsies Fraser Smith Is there still place for Endorectal Ultrassound Sthela Regadas 5 5 Thursday, November 19th The role of TEMS in assessment of response Chris Cunningham Discussion Maria Cristina Sartor / Lusmar Veras / Jorge Arias 18:00 Friday, November 20th 08:00 Overview of Trials with Organ Preservation for Rectal cancer Jean-Pierre Gerard Tumor Regression by Radiology & Pathology The role of mrTRG in assessment of response and ultimate management Gina Brown Interval between CRT and assessment of response: 6 or 12 weeks? Or longer deferral? Gina Brown Functional MR imaging - the Future... Regina Beets-Tan Extending the interval between CRT and surgery... Martin Weiser Discussion Ronaldo Salles / Magda Profeta da Luz / Paulo Mauricio Chagas Bruno Is any TRG system really useful? Which one? Mariana Berho 09:00 Discussion Maria Regina Vianna / Cinthia Ortega / Ruy Galves 19:00 19:30 Rectal Cancer after Neoadjuvant CRT Moderator: João Aguiar Pupo Neto Great Debates in Rectal Cancer II Is Local Excision justified in rectal cancer following CRT? Moderator: Chris Cunningham Lecture From no radiation and more surgery to more radiation and less surgery in rectal cancer management: The History of Neoadjuvant Therapy in Rectal Cancer Bruce Minsky President: Icaro Thiago de Carvalho No Ronan O’ Connell Yes Geerard Beets WELCOME COCKTAIL Discussion Mauro Pinho / Daniel Damin / Carlos Vaccaro Transanal Total Mesorectal Excision Moderator: Sergio Araújo Better option John Marks Welcome Cocktail Thursday - 19:30 No need Martin Weiser Casual Welcome Reception Discussion Ramon Mendes / Miguel Angelo Pedroso / Mauricio J. de Matos e Silva Vivaldi Room - WTC Convention Center 10:30 Break 11:00 Video Session: The difficult problems! Moderator: Rob Madoff Difficult TME Yves Panis Complications of Robotic Surgery Alessio Pigazzi Peritonial entry during TEM John Marks Laparoscopic lateral node dissection Tsuyoshi Konishi 6 6 7 7 Friday, November 20th Friday, November 20th Discussion Renato Lupinacci / Nicolas Rotholtz / Alejandro Barrera 12:00 Lunch Symposium Transanal Total Mesorectal Excision Symposium 13:30 Complete Clinical Response: Watch & Wait after a cCR? Moderator: Carlos Carvalho Yes Bruce Minsky No Rob Glynne-Jones Predicting Complete Response to CRT Rodrigo Perez Radiological Assessment of a CR Regina Beets-Tan 14:30 17:00 Recurrent Rectal Cancer Moderator: Paulo Hoff Surgical Management of Recurrent Rectal Cancer Torbjorn Holm November 20 – 12:00h Satellite Symposium How much more RT can we give? Daniel Chang Transanal Total Mesorectal Excision Symposium Moderator: Gustavo Rossi / Rodrigo Perez Is chemotherapy effective? Cathy Eng Why transanal TME? – Albert Wolthuis Equipment – What do I need for a taTME? John Marks Technique – Chris Cunningham Pitfalls and avoiding major complications… Greg Wynn Discussion Recurrence after TEM Chris Cunningham Recurrence after Watch & Wait Geerard Beets Discussion Lavoisier Fragoso D’Albuquerque / Artur Malzyner / Yoram Weissberger Discussion Jorge Sabbaga / Fernanda Caparelli / Diana Tait 18:30 Bringing Centers of Excellence to Center Stage in Rectal Cancer Management Steven Wexner Watch & Wait Moderator: Carlos Augusto Martinez 19:00 Happy Hour Satellite Symposium WORKSHOP The Maastricht Experience Geerard Beets Friday, November 20th The MSKCC Experience Martin Weiser 16:00 - 18:00 MRI in Rectal Cancer International Watch & Wait Database Nuno Figueiredo Gina Brown The Royal Marsden NHS Foundation Trust Surrey, UK Discussion Guilherme Cotti Cutait / Victor Seid Friday – 19:00h NOVADAQ Happy Hour Satellite Symposium New technologies in preventing anastomotic leaks - Fluorescence imaging for the assessment of bowel perfusion. Understanding and avoiding anastomotic leaks Failed methods of preventing leaks. Ronan O’Connell Why do anastomosis fail - An overview of the healing process. Mariana Berho 15:20 Past, Present and Future of rectal Cancer Management in the Era of Organ-Preservation Angelita Habr-Gama President: Fabio Campos 15:50 Break 16:20 The Role of Fluorescence Imaging in preventing anastomotic leaks. Steven Wexner Molecular Biology at Bedside - Liquid Biopsies Moderator: Jorge Sabbaga Discussion Liquid biopsies for the monitoring of tumor response to CRT Anamaria Camargo Liquid Biopsies for the monitoring of response to Chemotherapy Cathy Eng Q&A 8 8 9 9 Saturday, November 21th 07:30 Simposium Satellite (A light breakfast will be served) 08:30 Problems... When things go wrong November 21 – 7:30h WL GORE Satellite Symposium The colon will not reach the pelvis... Ronan O’Connell Advantages of BioA technology in the use of perineal and abdominal wound closure Complications after TEM Chris Cunningham Treatment of Bowel Dysfunction after TME Soren Laurberg Discussion 10:00 Abdominal Perineal Excision – The Rationale for the extra-levator approach. Torbjorn Holm Perineal Closure – The use of Flaps. Torbjorn Holm Perineal Closure – The use of Meshes. Guilherme Pagin São Julião Discussion Live Surgical Procedures Discussants: Afonso Sousa / Arceu Scanavini / Francisco Sérgio Regadas Olival Oliveira Jr / Oscar Tavella / Claudio Saddy R. Coy 08:00 Saturday, November 21th 08:00 - 11:00h Radiation Oncology Workshop President Secretary General Treasurer Angelita Habr-Gama Rodrigo Perez Carlos Eduardo Jacob Organizing Committee President: Joaquim Gama-Rodrigues Carlos Buchpiguel, SP Guilherme Pagin São Julião, SP Scientific Committee Ana Carolina Pereira de Sousa, SP Ariel Kann,SP Artur Malzyner, SP Carlos Augusto Martinez, SP Carlos W. Sobrado, SP Carmen Ruthe Manzione, SP Cinthia Ortega, SP Desidério Kiss, SP Eduardo de Paula Vieira, RJ Fábio Guilherme Campos, SP Discussion Pelvic anatomy subsites relevant for Radiation Oncologists. Vincenzo Valentini Discussion Tumor penetration in the mesorectum – Implications for the radiation therapy regimen. Jean-Pierre Gerard Discussion Break Indications for Neoadjuvant CRT. Rob Glynne Jones Chemotherapy without radiation as neoadjuvant treatment for rectal cancer. Does it work? Cathy Eng Discussion Metastatic Rectal Cancer Radiation therapy first. Rob Glynne-Jones Chemotherapy first. Cathy Eng Discussion 10 10 Icaro Thiago de Carvalho, SP Jorge Sabbaga, SP José Marcio N. Jorge, SP Lavoisier F. D’Albuquerque, SP Luis Fernando Mileo, SP Luiz A. Carneiro D’Albuquerque, SP Manuela V. Sapucahy, SP Maria Cristina Sartor, PR Maria José F. Vieira, SP Maria Regina Vianna, SP Maristela Gomes de Almeida, SP Mounib Tacla, SP Patrícia Bailão Aguilar, SP Rodrigo Oliveira, SP Ruy Galves, SP Sérgio E. A. Araujo, SP Venâncio Avancini F. Alves, SP Viviane Rawet, SP Yoram Weissberger, SP Guest Faculty Albert Wolthuis University Hospital Leuven Leuven, Belgium Alessio Pigazzi University of California, Irvine Orange, USA Bruce Minsky The University of Texas M.D. Anderson Cancer Center Houston, USA Tailoring the delineation of pelvic structures according to tumor presentation. Vincenzo Valentini Igor Proscurshim, SP Paulo Roberto Arruda Alves, SP Carlos Carvalho Champalimaud Clinical Centre Lisbon, Portugal Cathy Eng The University of Texas M.D. Anderson Cancer Center Houston, USA Chris Cunningham Churchill Hospital Oxford Oxford, UK Daniel Chang Stanford University Medical Center Stanford, USA Diana Tait The Royal Marsden NHS Foundation Trust Surrey, UK Dieter Hahnloser University Hospital Lausanne Lausanne, Switzerland Fraser Smith The Royal Liverpool and Broadgreen University Hospitals NHS Trust Liverpool, UK Geerard Beets Maastrich University Medical Center Maastricht, The Netherlands Gina Brown The Royal Marsden NHS Foundation Trust Surrey, UK Greg Wynn The ICENI Centre, Colchester General Hospital Colchester, UK Jean Pierre Gerard Antoine-Lacassagne Cancer Centre Nice, France John Marks Lankenau Medical Center Wynnewood, USA Mariana Berho Cleveland Clinica Florida Florida, USA Martin Weiser Memorial Sloane-Kettering Cancer Center New York, USA Nuno Figueiredo Champalimaud Clinical Centre Portugal Regina Beets Tan Maastrich University Medical Center Maastricht, The Netherlands Richard Heald Pelican Cancer Foundation Basingstoke, Hampshire, UK Rob Glynne-Jones Mount Vernon Centre for Cancer Treatment London, UK Robert D. Madoff University of Minnesota Minneapolis, USA Ronan O’Connell University College Dublin, St Vincent’s University Hospital Dublin, Ireland Soren Laurberg Aarhus University Aarhus, Denmark Steven Wexner Cleveland Clinica Florida Florida, USA Te Vuong Jewish General Hospital, McGill University Montreal, Canada Torbjorn Holm Karolinska Universitetsjukhuset Stockholm, Sweden Vincenzo Valentini Università Cattolica S. Cuore Roma, Italy Yves Panis Hôpital Beaujon, Clichy France 11 11 12 12 13 13 13 13 14 14 Organization Supported by Endorsing Societies and Institutions Sociedade Brasileira de Coloproctologia ACESP Associação de Coloproctologia do Estado de São Paulo Sociedade Brasileira de Radioterapia Sociedade Brasileira de Radiologia Sponsored by GIMED