CURRICULUM VITAE
Name: António Braz da Silva Parreira
Qualifications:
Diploma in Medicine - Lisbon University School of Medicine - 1972.
Haematology Board Certificate - Lisbon University School of Medicine, Santa Maria Hospital - 1979.
PhD in Haematology - Lisbon University School of Medicine - 1989.
Positions held:
Junior Assistant of Pharmacology - 1969-72.
Internship in Internal Medicine - 1973-74.
Resident in Internal Medicine, Santa Maria Hospital - 1975-76.
Resident in Haematology, Henri Mondor Hospital, Creteil, France, supported by a grant from the French
Government - 1977.
Resident in Clinical Haematology, Santa Maria Hospital, Lisbon 1977-80.
Consultant of Clinical Haematology, Santa Maria Hospital, Lisbon - since 1981-90.
Research Fellow at the Leukaemia Unit, Royal Postgraduate Medical School, Hammersmith Hospital,
London, supported by a grant from the Gulbenkian Foundation - 1983-85.
Assistant Professor of Immunology, Lisbon University School of Medicine, 1985-1989.
Consultant of Clinical Haematology, Portuguese Institute of Cancer, Lisbon, 1990.
Associate Professor of Haematology, Lisbon University School of Medicine, 1989-1992.
Present Appointment:
Head of Department of Clinical Haematology and the Hemato-Oncology Reseach Unit, Instituto
Português de Oncologia, Lisbon, since 1992.
Professor of Hematology
Faculdade Ciencias Medicas, Universidade Nova de Lisboa, since 1996.
Member of the following Scientific Societies:
Sociedade das Ciências Médicas de Lisboa
Sociedade Portuguesa de Hematologia
Association Espanola de Hematologia y Hemoterapia
The European Society for Medical Oncology
The International Society of Hematology
American Society of Hematology
Selected Publications:
Configuration of immunoglobulin and T-cell receptor ß and g genes in acute myeloid leukemia: pitffals in
the analysis of 40 cases. Parreira L, Carvalho C, Moura H, Melo A, Santos P, Guimaraes JE, Parreira A.
Journal of Clinical Pathology, 45;193-200, 1992.
Splenic lymphoma with villous lymphocytes in two sisters. I. Ribeiro, M.M. Costa, B.A. Fernandes, I.
Sousa, A. Melo, A. Parreira, L. Sousa Uva. Journal of Clinical Pathology, 45;1111-1113, 1992.
Myositis with tretinoin [letter] Miranda N, Oliveira P, Frade MJ, Melo J, Marques MS, Parreira A. Lancet
344: 1096, 1994.
Differential expression of cell adhesion molecules in the functional compartments of lymph-nodes and
tonsils. R.P. Leite, M. Carmo-Fonseca, J. Cabeçadas, A. Parreira, L. Parreira. Journal of Clinical
Pathology: Molecular 48:M93-M100, 1995.
Natural Killer cell numbers and activity in mobilized peripheral blood stem cell grafts: Conditions for in
vitro expansion. Silva MR, Parreira A, Ascensao JL. Experimental Hematology 23:1676-1681, 1995.
HTLV tax gene expression in patients with lymphoproliferative disorders. Cardoso EA, Miranda N,
Gameiro P, Frade MJ, Figueiredo M, Parreira A. Journal of Clinical Pathology 49:11 938J. 1996.
Large-Volume leukaphereses may be more efficient than standard-volume leukaphereses for collection of
peripheral blood progenitor cells. Passos-Coelho JL, Machado MA, Lucio P, Leal-da-Costa F, da Silva
MG, Parreira A. Journal of Hematotherapy 6:465-474, 1997
Expression of adhesion molecules on chronic B-cell lymphoproliferative disorders. Lucio P, Faria T, Pinto
A, Silva MRG, Junior E, Marques da Costa R, Parreira A. Haematologica 83: 104-111, 1998.
Flow cytometric analysis of normal B-cell differentiation: a frame of reference for the detection of minimal
residual disease in precursor B-ALL patients. Lucio P, Parreira A, van den Beemd MWM, van Lochem
EG, van Wering ER, Baars E, Porwit-MacDonald A, Bjorklund E, Gaipa G, Biondi A, Orfao A, van Dongen
JJM, San Miguel JF. Leukemia, 13; 419-27, 1999.
The Nuclear Topography of ABL, BCR, PML and RARa Genes: Evidence for gene proximity in specific
phases of the cell cycle and stages of hematopoietic differentiation. H. Neves, C. Ramos, M Gomes da
Silva, A. Parreira, L. Parreira. Blood, 4;1197-1207, 1999.
Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in Acute
Leukemia for detection of Minimal Residual Disease – Report of the BIOMED-1 Concerted Action:
Investigation of minimal residual disease in Acute Leukemia. JJM van Dongen, EA MacIntyre, E
Delabesse, JA Gabert, G Canniza, G Saglio, E Gottardi, A Rambaldi, P Dotti, F Griesinger, A Parreira, P
Gameiro, M Gonzalez Diaz, M Malec, AW Langerak, JF San Miguel, A Biondi. Leukemia 13:1901-1928
1999
CD123hi Dendritic Cell Lymphoma: An unusual case of Non-Hodgkin Lymphoma (NHL). P Lúcio, A
Parreira, A Orfao.. Annals Int Med 131(7):549-550, 1999.
Flow cytometric characterization of CD7+ cell subsets in normal bone marrow as a basis for the diagnosis
and follow up of T cell acute lymphoblastic leukemia ((T-ALL). A Porwit-MacDonald, E Bjorklund, P Lúcio,
EG van Lochem, J Mazur, A Parreira, MWM van den Beemd, ER van Wering, E Baars, G Gaipa, A
Biondi, J Ciudad, JJM van Dongen, JF San Miguel, A Orfao. Leukemia 14:816-825, 2000
High remission rate in T-cell prolymphocytic leukemia with CAMPATH-1H. Dearden CE, Matutes E, Cazin
B, Tjonnfjord GE, Parreira A, Nomdedeu B, Leoni P, Clark FJ, Radia D, Rassam SM, Roques T, Ketterer
N, Brito-Babapulle V, Dyer MJ, Catovsky D. Blood Sep 15;98(6):1721-6, 2001
BIOMED-I concerted action report: flow cytometric immunophenotyping of precursor B-ALL with
standardized triple-stainings. BIOMED-1 Concerted Action Investigation of Minimal Residual Disease in
Acute Leukemia: International Standardization and Clinical Evaluation. Lucio P, Gaipa G, van Lochem
EG, van Wering ER, Porwit-MacDonald A, Faria T, Bjorklund E, Biondi A, van den Beemd MW, Baars E,
Vidriales B, Parreira A, van Dongen JJ, San Miguel JF, Orfao A. Leukemia. Aug;15(8):1185-92, 2001
The PML-RARa transcript in long-term follow-up of acute promyelocytic leukemia patients. Gameiro P,
Vieira S, Carrara P, Silva AL, Diamond J, de Sousa AB, Mehta AB, Prentice HG, Guimaraes JE,
Hoffbrand AV, Foroni L, Parreira A.Haematologica Jun;86(6):577-85, 2001
Autologous peripheral stem cell transplantation for multiple myeloma in a patient with a 10 year-old
kidney transplant: case report and clinical issues. Rego F, Alcantara P, Buinho F, Araujo F, Santos JM,
Parreira A, da Costa FL.Transplant Proc. 2003 May;35(3):1102-4.
Clonality analysis for antigen receptor genes: preliminary results from the Biomed-2 concerted action PL
96-3936. van Krieken JH, Langerak AW, San Miguel JF, Parreira A, Smith JL, Morgan GM, Kneba M,
Macintyre EA, van Dongen JJ. Hum Pathol. 2003 Apr;34(4):359-61