ISSN-1807-5932 CLINICS CONTENTS Clinics 2012 67(7):697–857 CLINICAL SCIENCES Renal macrophage infiltration is associated with a poor outcome in IgA nephropathy Gyl Eanes Barros Silva, Roberto Silva Costa, Roberto Cuan Ravinal, Leandra Naira Zambelli Ramalho, Marlene Antonia dos Reis, Miguel Moyses-Neto, Elen Almeida Romao, Terezila Machado Coimbra, Márcio Dantas . . . . . . . 697 Histopathological evaluation and risk factors related to the development of pouchitis in patients with ileal pouches for ulcerative colitis Roberta Thiery de Godoy Arashiro, Magaly Gemio Teixeira, Viviane Rawet, Alina Guimarães Quintanilha, Henrique Moura de Paula, Adriano Zanon Silva, Sérgio Carlos Nahas, Ivan Cecconello . . . . . . . . . . . . . . . . . . . . . . . . . . . . 705 Metformin, but not glimepiride, improves carotid artery diameter and blood flow in patients with type 2 diabetes mellitus Helena Atroch Machado, Marcelo Vieira, Maria Rosaria Cunha, Marcia Regina Soares Correia, Rosa Tsunechiro Fukui, Rosa Ferreira dos Santos, Dalva Marreiro Rocha, Bernardo Leo Wajchenberg, Silvia G. Lage, Maria Elizabeth Rossi da Silva . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 711 Association between functional alterations of senescence and senility and disorders of gait and balance Homero Teixeira-Leite, Alex C. Manhães . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 719 Disparities in female breast cancer mortality rates in Brazil between 1980 and 2009 Ruffo Freitas-Junior, Carolina Maciel Reis Gonzaga, Nilceana Maya Aires Freitas, Edesio Martins, Rita de Cássia de Maio Dardes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 731 Frequency and predictors of symptomatic intracranial hemorrhage after intravenous thrombolysis for acute ischemic stroke in a Brazilian public hospital Pedro Telles Cougo-Pinto, Bruno Lopes dos Santos, Francisco Antunes Dias, Soraia Ramos Cabette Fabio, Ilana Vaula Werneck, Millene Rodrigues Camilo, Daniel Giansante Abud, João Pereira Leite, Octavio Marques Pontes-Neto . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 739 T-cell large granular lymphocytic leukemia: treatment experience with fludarabine Renata Oliveira Costa, Marcelo Bellesso, Dalton Alencar Fischer Chamone, Milton Artur Ruiz, Abrahão Elias Hallack Neto, Vera Lucia Aldred, Juliana Pereira . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 745 Trends and characteristics of pethidine use in Taiwan: a six-year-long survey Hsueh-Hsing Pan, Chung-Yi Li, Tso-Chou Lin, Ju-O Wang, Shung-Tai Ho, Kwua-Yun Wang . . . . . . . . . . . . . . . . 749 Postural control in women with breast hypertrophy Alessandra Ferreira Barbosa, Gabriela Cristina Raggi, Cristina dos Santos Cardoso Sá, Márcio Paulino Costa, Jonas Eraldo de Lima Junior, Clarice Tanaka. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 757 Renal oxygen content is increased in healthy subjects after angiotensin-converting enzyme inhibition Anna Stein, Silvia Goldmeier, Sarah Voltolini, Enio Setogutti, Carlos Feldman, Eduardo Figueiredo, Renato Eick, Maria Irigoyen, Katya Rigatto . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 761 Noninvasive positive-pressure ventilation in clinical practice at a large university-affiliated Brazilian hospital Liria Yuri Yamauchi, Teresa Cristina Francischetto Travaglia, Sidnei Ricardo Nobre Bernardes, Maise C. Figueiroa, Clarice Tanaka, Carolina Fu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 767 Pulse pressure variation and prediction of fluid responsiveness in patients ventilated with low tidal volumes Clarice Daniele Alves de Oliveira-Costa, Gilberto Friedman, Sı́lvia Regina Rios Vieira, Léa Fialkow . . . . . . . . . . . . 773 BASIC RESEARCHES Protective effects of Tualang honey on bone structure in experimental postmenopausal rats Siti Sarah Mohamad Zaid, Siti Amrah Sulaiman, Nor Hayati Othman, Ima-Nirwana Soelaiman, Ahmad Nazrun Shuid, Norazlina Mohamad, Norliza Muhamad . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 779 Rat testicular impairment induced by electromagnetic radiation from a conventional cellular telephone and the protective effects of the antioxidants vitamins C and E Mona Abdullah Al-Damegh . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 785 The use of vancomycin-loaded poly-l-lactic acid and poly-ethylene oxide microspheres for bone repair: An in vivo study Débora Cristina Coraça-Huber, Eliana Aparecida de Rezende Duek, Maurı́cio Etchebehere, Luis Alberto Magna, Eliane Maria Ingrid Amstalden . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 793 Time-related effects of general functional training in spinal cord-injured rats Taisa Amoroso Bortolato Miranda, Juliana Mendes Yule Vicente, Raphael Martus Marcon, Alexandre Fogaça Cristante, Edgard Morya, Angela Cristina do Valle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 799 The imbalance between Treg and Th17 cells caused by FTY720 treatment in skin allograft rejection Alessandra Gonçalves Commodaro, Juliana Figueredo Pedregosa, Jean Pierre Peron, Wesley Brandão, Luiz Vicente Rizzo, Valquiria Bueno . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 805 Exercise training prevents diastolic dysfunction induced by metabolic syndrome in rats Cristiano Mostarda, Ivana Cinthya Moraes-Silva, Vera Maria Cury Salemi, Jacqueline Freire Machi, Bruno Rodrigues, Kátia De Angelis, Vera de Moura Azevedo Farah, Maria Claudia Irigoyen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 815 S100B protein expression in the heart of deceased individuals by overdose: a new forensic marker? Armando Faa, Giancarlo Senes, Annalisa Locci, Pietro Pampaloni, Maria Elena Pais, Bruno Piras, Ernesto d’Aloja, Gavino Faa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 821 REVIEWS Wound-healing and benzodiazepines: does sleep play a role in this relationship? Flavia Egydio, Gabriel Natan Pires, Sergio Tufik, Monica Levy Andersen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 827 Clinical pharmacokinetics of vancomycin in the neonate: a review Gian Maria Pacifici, Karel Allegaert . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 831 Does calcium intake affect cardiovascular risk factors and/or events? Márcia Regina Simas Gonçalves Torres, Antonio Felipe Sanjuliani . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 839 RAPID COMMUNICATION Anaplastic lymphoma kinase gene rearrangement in non-small-cell lung cancer in a Brazilian population Lisandro F. Lopes, Carlos E. Bacchi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 845 CASE REPORTS The surgical removal of a live tapeworm with an interesting pathologic finding most likely representing the migration path: a case report of cerebral sparganosis Peng Wang, Xueying Su, Qing Mao, Yanhui Liu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 849 Giant obstructive left atrial myxoma resembling mitral valve stenosis Solange Desirée Avakian, Julio Yoshio Takada, Antonio de Padua Mansur . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 853 Spinal hematoma complicating a Churg-Strauss syndrome patient: a previously unreported association Camila Cristina Kukita, André Luiz Nunes Gobatto, Alice Zoghbi Lobo, Leandro Utino Taniguchi. . . . . . . . . . . . . 855