Curriculum vitae PERSONAL INFORMATION Joao Freire WORK EXPERIENCE January 1993–December 1994 Medical doctor Hospital de Pulido Valente, (Portugal) Junior resident in training. January 1995–February 2001 Medical doctor Instituto Português de Oncologia, (Portugal) Fellowship in Medical Oncology 2001–Present Medical doctor Instituto Português de Oncologia, (Portugal) Assistant in Medical Oncology November 2013–Present Medical doctor INFARMED - National Authority of Medicines and Health Products, I. P., (Portugal) ▪ Member of the drug evaluation committee 1997–Present Clinical research Instituto Português de Oncologia, (Portugal) Paricipated as co-investigator, investigator and national coordinator in several clinical trials EDUCATION AND TRAINING October 1986–July 1992 Medical doctor Faculdade de Ciências Médicas, Universidade Nova de Lisboa, (Portugal) Medical school 2007–2008 Post-graduation in Palliative Care Universidade Católica Portuguesa, (Portugal) ADDITIONAL INFORMATION Expertise Medical Oncology - anticancer drugs, support Palliative care Drug evaluation Publications Projects Academic trials and publicly funded research: - p53 Study ? First prospective Intergroup Translational Research Trial assessing the potential predictive value of p53 using a functional assay in yeast in patients with locally advanced/inflammatory or large operable breast 14/2/15 © European Union, 2002-2015 | http://europass.cedefop.europa.eu Page 1 / 2 Curriculum vitae Joao Freire cancer prospectively randomised to a taxane versus a non taxane regimen. (EORTC Breast Group Protocol n. 10994). Date of activation: 2001. - "Ensaio de fase II de quimioradioterapia sequencial e concomitante no carcinoma espinocelular do canal anal." (IPO-Lisbon). Date of activation: 2002. Closed December 2006. - Adjuvant Treatment of Fully Resected Stage III Colon Cancer with FOLFOX-4 versus FOLFOX-4 plus Cetuximab ? PETACC-8. The EORTC "Gastrointestinal Tract Cancer Group". Date of activation: March 2007. - "Estudo de adesão à terapêutica e efectividade de ECX (Epirubicina, Cisplatina e capecitabina ? Xeloda®) no tratamento de primeira linha de doentes com carcinoma gástrico metastático ou localmente avançado" (IPO ? Lisbon) - "Análise de minimização de custos de ECX em comparação com ECF no tratamento de primeira linha de doentes com carcinoma gástrico metastático ou localmente avançado" (IPO ? Lisbon) - "Metástases hepáticas de carcinoma do cólon e recto ? Avaliação por RM da resposta à quimioterapia neoadjuvante através da quantificação dos valores do Apparent Diffusion Coeficient" (IPO ? Lisbon) - Effectiveness of first line treatment with lapatinib and ECF/X in histologically proven adenocarcinoma of the stomach or the esophagogastric junction, metastatic or not amenable to curative surgery according to HER2 and EGFR status: a randomized phase II trial. (EORTC Gastrointestinal Tract Cancer Group) - Screening Platform of the EORTC for Clinical Trials in Advanced Colorectal cancer "SPECTAColor" (EORTC Gastrointestinal Tract Cancer Group) - INtegration of trastuzumab, with or without pertuzumab, iNto periOperatiVe chemotherApy of HER-2 posiTIVe stOmach caNcer: The INNOVATION trial (EORTC Gastrointestinal Tract Cancer Group) - Evaluation of diffusion weighted imaging -MRI in patients with resectable liver metastases from colorectal cancer treated with fluoropyrimidine-based chemotherapy as preoperative chemotherapy (EORTC Gastrointestinal Tract Cancer Group; EORTC Imaging Group) - Low Rectal Cancer Study (MERCURY 2 Study Research Group) - Homologous recombination deficiency as prognostic marker in metastatic gastric cancer. (Health Cluster Portugal) - InterAACT TRIAL (the International Rare Cancer Initiative (IRCI) group; EORTC Gastrointestinal Tract Cancer Group) Memberships EORTC GastroIntestinal Tumors Study Group Other Relevant Information 14/2/15 © European Union, 2002-2015 | http://europass.cedefop.europa.eu Page 2 / 2