The POLARIS Conference Challenges in Nanomedicine and Regenerative Medicine Vila Flor Culture Centre (CCVF), Guimarães, Portugal 29 June | 01 July, 2015 Day 1 | Monday, June 29 09.00-09.30 Registration (Foyer) 09.30-10.00 Welcome and Opening Remarks Rui L. Reis (3B´s Research Group, University of Minho, Portugal | Director | The POLARIS Conference Chair) Nanostructures for Biomedical Applications Chair: Changyou Gao | Co-Chair: Rui L. Reis 10.00-11.00 PL01 - Dendritic Nanostructures for Biomedical Applications E. Fernández-Mejía (University of Santiago de Compostela, Spain) 11.00-11.30 Coffee break | Poster Session 11.30-12.30 PL02 - Nanobiopolymeric-based systems in regenerative medicine J. Mano (University of Minho, Portugal) 12:30-14:30 Lunch (Café-Concerto) Cell-Nanomaterial Interactions Chair: Eduardo Fernández-Mejía | Co-Chair: João Mano 14.30-15.30 PL03 - Designed biomaterials for mediating cell migration and cellular uptake C. Gao (Zhejiang University, China) Short Oral Presentations I Chair: Eduardo Fernández-Mejía | Co-Chair: João Mano 15.30-15.45 15.45-16.00 16.00-16.15 POL04 - Surface engineered gold nanorods: a valuable asset for bone tissue engineering S. Vial, F. R. Maia, S. Vieira, P. L. Granja, R. L. Reis, J. M. Oliveira 3B´s Research Group, University of Minho, Portugal POL05 - In vivo imaging modalities to visualize stem cells and biomaterial applications in the mouse brain using GlowBrain platform Igor Pongrac, Marina Dobrivojevic, Dunja Gorup, Dora Polsek, Lada Brkic Ahmed, Lejla Ferhatovic Hamzic, Marija Lovric, Marija Curlin, Srecko Gajovic POL09 - In vivo evaluation of silk fibroin hydrogel as suppressor of angiogenesis and tumor progression J. Silva-Correia, V. Ribeiro, V. Miranda-Gonçalves, L-P. Yan, A. L. Oliveira, R. M. Reis, J. M. Oliveira, R. L. Reis 3B´s Research Group, University of Minho, Portugal 16.15-16.30 POL01 - Glycan nanoarrays for elucidation of cell adhesion mechanisms R. Novoa-Carballal, R. Teixeira, D. Soares da Costa, R. A. Pires, R. L. Reis, J. P. Spatz, I. Pashkuleva 3B´s Research Group, University of Minho, Portugal 16.30-17.00 Coffee break | Poster Session 1 The POLARIS Conference Challenges in Nanomedicine and Regenerative Medicine Vila Flor Culture Centre (CCVF), Guimarães, Portugal 29 June | 01 July, 2015 Invited Young Presentations I Chair: Ivan Wall | Co-Chair: Rui L Reis 17.00-17.20 POL03 - Molecularly imprinted polymers capture biomolecules in consideration of molecular weight and isoelectric point J. R. Clegg, H. R. Culver, J. Zhong, A. S. Irani, N. A. Peppas University of Texas at Austin, USA 17.20-17.40 POL19 - Reconstitution of actomyosin cortex and adhesion-associated proteins in droplet-based synthetic cells I. Platzman, J.-W. Janiesch, J. P. Frohnmayer, M. Weiss, J. P. Spatz Max Planck Institute for Intelligent Systems, Germany 17.40-18.30 18:30-20:00 Welcome Cocktail (CCVF) Day 2 | Tuesday, June 30 Processing of biodevices for the regenerative medicine Chair: João Mano | Co-Chair: Changyou Gao 09.00-10.00 PL04 - New bioprocessing tools for manufacture and measurement of regenerative medicine products I. Wall (University College London, UK) Short Oral Presentations II Chair: João Mano | Co-Chair: Changyou Gao 10.00-10.15 10.15-10.30 10.30-10.45 POL10 - Ionic-substituted tricalcium phosphate nanostructures for osteochondral tissue engineering S. Pina, J.M. Oliveira, R.L. Reis 3B´s Research Group, University of Minho, Portugal POL20 - A microfluidic strategy for oil-free cell encapsulation L. Gasperini, J. F. Mano, R.L. Reis 3B´s Research Group, University of Minho, Portugal POL21 - Development of magnetic responsive hASCs sheets for tendon regeneration A. I. Gonçalves, P. M. Gershovich, M. T. Rodrigues, R. L. Reis, M. E. Gomes 3B´s Research Group, University of Minho, Portugal 10.45-11.00 POL22 - Nanoparticle-induced bioprinted liver for drug screening and tissue regeneration A. da Silva Morais, R. A. Sousa, J. M. Oliveira, R. L. Reis 3B´s Research Group, University of Minho, Portugal 11.00-11.30 Coffee break | Poster Session 11.30-12.30 PL05 - Biodegradable and bioactive scaffolds for Tissue Engineering prepared in cryogenic conditions. A single approach for the fabrication of porous hybrid systems J. San Roman (CSIC, Madrid, Spain) 12:30-14:30 Lunch (Café-Concerto) 2 The POLARIS Conference Challenges in Nanomedicine and Regenerative Medicine Vila Flor Culture Centre (CCVF), Guimarães, Portugal 29 June | 01 July, 2015 Invited Young Presentations II Chair: Julio San Roman | Co-Chair: Ivan Wall 14.30-14.50 POL02 - Responsive polymer based nanobiosensors for diagnostic applications H. R. Culver, N. A. Peppas University of Texas at Austin, USA 14.50-15.10 POL 24 - Gene therapy for tissue engineering: combination of scaffolds with stem cells and gene delivery techniques E. R. Balmayor Technical University Munich, Germany 15.10-15.30 POL18 - Discovery of tri-peptide emulsifiers using combined computational screening and experimental validation G.G. Scott, T. Tuttle, R. V. Ulijn University of Strathclyde, UK Self-assembling systems Chair: Rui L Reis | Co-Chair: Eduardo Fernández-Mejía 15.30-16.30 PL06 - Nanoscale molecular assemblies in cellular environment: From molecules to processes B. Xu (Brandeis University, USA ) 16.30-17.00 Coffee break | Poster Session Short Oral Presentations III Chair: Rui L Reis | Co-Chair: Eduardo Fernández-Mejía 17.00-17.15 POL08 - Biomimetic glycan nanocarriers for encapsulation of FGF-2 C. Silva, R. Novoa-Carballal, R. L. Reis, I. Pashkuleva 3B´s Research Group, University of Minho, Portugal 17.15-17.30 POL07 - Self-assembled periosteum-like membranes for bone regeneration S. C. Ribeiro, D. S. Ferreira, I. B. Leonor, R. L. Reis, A. Mata, H. S. Azevedo 3B´s Research Group, University of Minho, Portugal 17.30-17.45 POL15 - Role of exogenous hyaluronic acid molecular weight on CD44-mediated adhesion S. Amorim, D. Soares da Costa, D. Freitas, A. Magalhães, C. Reis, R.L. Reis, I. Pashkuleva, R. Pires 3B´s Research Group, University of Minho, Portugal 17.45-18.00 POL11 - Development of polymeric nanoparticles and liposomes as devices for theranostic and monitoring of specific diseases H. Ferreira, M. L. Alves da Silva, A. Martins, R. L. Reis, N. M. Neves 3B´s Research Group, University of Minho, Portugal 18.00-18.30 Walk to Paço dos Duques 18.30-20.00 Guided Tour to Paço dos Duques 20.00-... The POLARIS Conference Dinner (Paço dos Duques) 3 The POLARIS Conference Challenges in Nanomedicine and Regenerative Medicine Vila Flor Culture Centre (CCVF), Guimarães, Portugal 29 June | 01 July, 2015 Day 3 | Wednesday, July 01 Bioinspired molecular systems Chair: Bing Xu | Co-Chair: Julio San Roman 09.00-10.00 PL07 - Bio-inspired building blocks for organic nanotechnology E. Gazit (Tel Aviv University, Israel) Short Oral Presentations IV Chair: Bing Xu | Co-Chair: Julio San Roman 10.00-10.15 10.15-10.30 10.30-10.45 10.45-11.00 POL12 - Cell derived-extracellular vesicles: the next-generation nano-systems for targeted delivery M. Martins, D. Ribeiro, A. Martins, R.L. Reis, N.M. Neves 3B’s Research Group, University of Minho, Portugal POL14 - Cork polyphenols as an unconventional approach against Machado-Joseph disease A. R. Araújo, A. Jalles, P. Maciel, R. L. Reis, A. Teixeira-Castro, R. A. Pires 3B’s Research Group, University of Minho, Portugal POL17 - Phenolic-based chemicals from cork as inhibitors of amyloid-beta aggregation: a therapeutical strategy for Alzheimer’s disease S. Camero, A. R. Araújo, R. L. Reis, R. A. Pires 3B’s Research Group, University of Minho, Portugal POL23 - Kefiran, a promising biopolymer for cartilage tissue engineering H. Radhouani, C. Gonçalves, J.M. Oliveira, R.L. Reis 3B’s Research Group, University of Minho, Portugal 11.00-11.30 Coffee break | Poster Session 11.30-12.30 PL08 - Recent advances for cornea tissue engineering G. Khang (Chonbuk National University, South Korea) 12.30-13.00 Closing Remarks POSTERS LIST POL06 Kaempferol: pluripotency enhancer and natural stem cell killer – just a question of imbalances M. Correia, A. S. Rodrigues, S. L. Pereira, T. Perestrelo, M. I. Sousa, M. F. Ribeiro, J. Ramalho-Santos University of Coimbra, Portugal POL13 Development of antibacterial surfaces bioinspired on the micro/nanotopography of natural surfaces M. B. dos Santos, A. Franco, T. H. Silva, F. Rodrigues, A. G. Castro, I. B. Leonor, R. L. Reis 3B’s Research Group, University of Minho, Portugal POL16 Establishing 3D culture of endocervical secretory cells for evaluation the role of GABA in the regulation of their activity M. Ćurlin, M. Skelin, M. Boban, S. Gajović University of Zagreb, Croatia 4