Curriculum Vitae João Santana Silva Name: Nationality: Work address: Joao Santana da Silva Brazilian Medical School of Ribeirão Preto Av. Bandeirantes 3900 14049-900 Ribeirão Preto, SB Brazil E-mail: [email protected] Education/Training: Year Title of activity 2004 Full Professor 1997 Associate Professor 1991 Pos-Doc 1983 PhD 1979 Master Degree Professional History 1981-present Institution USP USP Seattle Biomedical Reserch Inst. USP USP Medical School of Ribeirão Preto USP Students: I have mentored 23 PhD, 31 M.Sc. and 17 Post-docs students. Memberships: Brazilian Society of Immunology Brazilan Society of Protozoology Brazilian Academy of Science Research Interest: Infection and Immunity Recent publications (of a total of 226) 1: Sales-Campos H, de Souza PR, Peghini BC, da Silva JS, Cardoso CR. An Overview of the Modulatory Effects of Oleic Acid in Health and Disease. Mini Rev Med Chem. 2012. [Epub ahead of print]. 2: Sesti-Costa R, Silva JS, Gutierrez FR. Congenital Chagas disease: time to screen pregnant women? Expert Rev Anti Infect Ther. 2012 Nov;10(11):1279-82. 3: Gasparoto TH, de Oliveira CE, de Freitas LT, Pinheiro CR, Ramos RN, da Silva AL, Garlet GP, da Silva JS, Campanelli AP. Inflammatory events during murine squamous cell carcinoma development. J Inflamm (Lond). 2012 Nov 23;9(1):46. 4: Salehi S, Bankoti R, Benevides L, Willen J, Couse M, Silva JS, Dhall D, Meffre E, Targan S, Martins GA. B Lymphocyte-Induced Maturation Protein-1 Contributes to Intestinal Mucosa Homeostasis by Limiting the Number of IL-17-Producing CD4+ T Cells. J Immunol. 2012 Dec 15;189(12):5682-93 5: Malinsky RR, Valera FC, Cavallari FE, Küpper DS, Milaneze C, Silva JS, Tamashiro E, Anselmo-Lima WT. Matrix metalloproteinases and their impact on sinusal extension in chronic rhinosinusitis with nasal polyps. Eur Arch Otorhinolaryngol. 2012 Oct 12. [Epub ahead of print] 6: Dellalibera-Joviliano R, Joviliano EE, Silva JS, Evora PR. Activation of cytokines corroborate with development of inflammation and autoimmunity in thromboangiitis obliterans patients. Clin Exp Immunol. 2012 Oct;170(1):28-35. 7: Cavallari FE, Valera FC, Gallego AJ, Malinsky RR, Küpper DS, Milanezi C, da Silva JS, Tamashiro E, Anselmo-Lima WT. Expression of RANTES, eotaxin-2, ICAM-1, LFA-1 and CCR-3 in chronic rhinosinusitis patients with nasal polyposis. Acta Cir Bras. 2012 Sep;27(9):645-9. 8: Godoi DF, Cardoso CR, Silva MJ, Ferraz DB, Provinciatto PR, Cunha FD, da Silva JS, Voltarelli JC. Reappraisal of total body irradiation followed by bone marrow transplantation as a therapy for inflammatory bowel disease. Immunobiology. 2012 May 23. [Epub ahead of print]. 9: Matta Guedes PM, Gutierrez FR, Nascimento MS, Do-Valle-Matta MA, Silva JS. Antiparasitical chemotherapy in Chagas' disease cardiomyopathy: current evidence. Trop Med Int Health. 2012 Sep;17(9):1057-65. 10: Gonçalves D, de Queiroz Prado R, Almeida Xavier E, Cristina de Oliveira N, da Matta Guedes PM, da Silva JS, Moraes Figueiredo LT, Aquino VH. Imunocompetent mice model for dengue virus infection. Scientific World Journal. 2012;1-12. 11: Guedes PM, Gutierrez FR, Silva GK, Dellalibera-Joviliano R, Rodrigues GJ, Bendhack LM, Rassi A Jr, Rassi A, Schmidt A, Maciel BC, Marin Neto JA, Silva JS. Deficient regulatory T cell activity and low frequency of IL-17-producing T cells correlate with the extent of cardiomyopathy in human Chagas' disease. PLoS Negl Trop Dis. 2012;6(4):e1630. 12: Rodrigues AA, Saosa JS, da Silva GK, Martins FA, da Silva AA, Souza Neto CP, Horta CV, Zamboni DS, da Silva JS, Ferro EA, da Silva CV. IFN-γ plays a unique role in protection against low virulent Trypanosoma cruzi strain. PLoS Negl Trop Dis. 2012;6(4):e1598. 13: Repeke CE, Cardoso CR, Claudino M, Silveira EM, Trombone AP, Campanelli AP, Silva JS, Martins W Jr, Garlet GP. Non-inflammatory destructive periodontal disease: a clinical, microbiological, immunological and genetic investigation. J Appl Oral Sci. 2012 Feb; 20(1): 113-21. 14: Ramos RN, Oliveira CE, Gasparoto TH, Malaspina TS, Belai EB, Cavassani KA, Garlet GP, Silva JS, Campanelli AP. CD25+ T cell depletion impairs murine squamous cell carcinoma development via modulation of antitumor immune responses. Carcinogenesis. 2012 Apr;33(4):902-9. 15: Zarpelon AC, Pinto LG, Cunha TM, Vieira SM, Carregaro V, Souza GR, Silva JS, Ferreira SH, Cunha FQ, Verri WA Jr. Endothelin-1 induces neutrophil recruitment in adaptive inflammation via TNFα and CXCL1/CXCR2 in mice. Can J Physiol Pharmacol. 2012 Feb;90(2):187-99. 16: Silva JS, Andrade AC, Santana CC, Santos LQ, Oliveira CI, Veras PS, Vassallo J, dosSantos WL. Low CXCL13 expression, splenic lymphoid tissue atrophy and germinal center disruption in severe canine visceral leishmaniasis. PLoS One. 2012;7(1):e29103. 17: Caetano BC, Biswas A, Lima DS Jr, Benevides L, Mineo TW, Horta CV, Lee KH, Silva JS, Gazzinelli RT, Zamboni DS, Kobayashi KS. Intrinsic expression of Nod2 in CD4+ T lymphocytes is not necessary for the development of cell-mediated immunity and host resistance to Toxoplasma gondii. Eur J Immunol. 2011 Dec;41(12):3627-31. 18: Cavassani KA, Tristao FS, Oliveira LL, Rocha FA, Vancim JO, Moreira AP, Campanelli AP, Panagio LA, Milanezi CM, Martinez R, Rossi MA, Silva JS. Cell-free antigens from Paracoccidioides brasiliensis drive IL-4 production and increase the severity of paracoccidioidomycosis. PLoS One. 2011;6(6):e21423.