Reciprocal Changes Assessment in Adjacent Mobile Level following Monosegmentar Interbody Fusion Enrique Vargas, Rodrigo Amaral, Luis Marchi, Leonardo Oliveira, Fernanda Fortti, Etevaldo Coutinho, Rubens Jensen Instituto de Patologia de Coluna (IPC) - São Paulo - Brazil 2015 DISCLOSURE • • • • • • • Enrique Vargas; nothing to disclose Rodrigo Amaral ; consultant (NuVasive) Luis Marchi ; nothing to disclose Leonardo Oliveira ; nothing to disclose Fernanda Fortti ; nothing to disclose Etevaldo Coutinho ; nothing to disclose Rubens Jensen; consultant (NuVasive) IPC - grant/research support (MDT implantes) Background • 60% of the overall lumbar lordosis is located in L4L5 and L5S1 • The main cause of sagittal imbalance in degenerative lumbar spine is the loss of lumbar lordosis • With DDD, index lordosis is extremelly diminished and can lead to segmental and global imbalance • The pelvis may also be retroversed, resulting in a decreased sacral slope to compensate for the sagittal imbalance • Postoperative improvement in L5 incidence and slip angle has been correlated with better outcomes. J Neurosurg Spine 7:387–392, 2007 Objective The purpose of this paper is to analyze the contribution of a standalone L5S1 interbody procedure toward the treatment of degenerative disc disease and study resultant local sagittal parameters Hypothesis In DDD L5S1 ↓ L5S1 lordosis; ↑ L4L5 lordoses After ALIF in L5S1 ↑ L5S1lordosis; ↓ L4L5 lordoses Inclusion/ Exclusion Inclusion stenosis, DDD, instability and/or low-grade spondylolisthesis diagnosis stand-alone L5S1 ALIF with selflocking lordotic interbody cage Exclusion previous lumbar fusion Radiological measures 2 independent evaluators • X-rays orthostatic neutral – Preop – 3 months Lumbar lordosis L4L5 lordosis L5S1 lordosis Sacral slope L5 takeoff A B Study cohort • 35 cases • 25 F /10 M • 47±15 y/o Radiological results Tabela 1. Reciprocal changes following L5S1 ALIF Preop 3 months Pre x 3m; p a Pre x Pre; p b L5S1 level 19° ± 8° 28° ± 5° <0.001* 0.091 L4L5 level 17° ± 6° 14° ± 5° <0.001* L5S1 disc 10° ± 7° 18° ± 4° <0.001* 0.024* L4L5 disc 12° ± 4° 9° ± 3° <0.001* Lumbar Lordosis 52° ± 10° 53° ± 12° 0.461 L5 takeoff 17° ± 9° 13° ± 9° 0.007* Sacral Slope 37° ± 9° 40° ± 9° 0.002* - 3m x 3m; p c <0.001* <0.001* - Mean ± Standard Deviation. * statistically significant. (a) Preop versus 3 months. (b) Preop versus Prep. (c)3 months versus 3 months. Resultados Radiológicos L5S1 lordosis gain; L4L5 lordosis loss L4L5 x L5S1 lordosis change 2,0 0,0 -10 -5 0 -2,0 -4,0 -6,0 -8,0 -10,0 -12,0 5 10 15 20 25 Exemples #1 #2 Exemples #3 #4 Conclusion Lumbar lordosis is not affected by L5S1 ALIF Reduction of compensatory lordosis of the adjacent mobile level after ALIF with disc height and lordosis restoration of index level. Maintenance of physiological sagittal parameters in levels adjacent to fusion could reflect in lower rates of ALD.