Curriculum Vitæ
Maria Fernanda Martins Borges
Faculty Pharmacy of Porto
University of Porto
2008
CURRICULUM VITAE
Maria Fernanda Martins Borges
Born 13 January 1959
Position and Affiliation
Professor. Organic Chemistry Department, Faculty of Pharmacy, University of Porto
(FFUP), Portugal
Email: [email protected]
Education
1982
Graduation in Pharmaceutical Sciences (5 years curriculum), University
of Porto
1983 – 1987 Speciality training in Pharmaceutical Chemistry (combines pedagogic
and scientific formation), University of Porto
1995
PhD (Pharmaceutical Chemistry), University of Porto
2004
Highest University Degree (“Agregação”), University of Porto
Professional Experience
1983 –1987 Training Assistant, Organic Chemistry Department, School of
Pharmacy, University of Porto
1987 – 1995 Assistant, Organic Chemistry Department, School of Pharmacy,
University of Porto
1995 – 2000 Assistant Professor, Organic Chemistry Department, School of
Pharmacy, University of Porto
2004- present Professor with “Agregação, Organic Chemistry Department, School of
Pharmacy, University of Porto
Scientific experience
National Project coordinator and coinvestigator of the following projects funded,
or under evaluation, by Fundação para a Ciência e Tecnologia.
“Hepatotoxic and cardiotoxic studies of methylenedioxymetamphetamine (“ecstasy”)
and its metabolites in Wistar Rats”; “Development of new anticancer agents: phenolic
derivatives of natural or synthetic origin.structure-activity relationships”; “The
protective role of adenosine in vascular inflammation: molecular mechanisms and
clinical implications” “Biochemical and behaviour study of the interactions opiatescocaine” “Design, Synthesis and Characterization of Cinnamic Derivatives With
Preferential Effects on Mitochondria: Searching for Novel Antiproliferative, Antitumor
and Antioxidant Agents“New therapeutic approaches in cancer: Rational design and
synthesis of new adenosine A3 receptor ligands” “Microgial and neuronal changes in
the hippocampus induced by methamphetamine: role of pro-inflammatory cytokines
and neuropeptideY” “The role of the neuron-astrocyte unit, glutamate and GABA on
the methamphetamine-induced nigrostriatal toxicity” “Residual pharmaceutical agents
in hospital effluent waste waters: occurrence, fate, removal and impact” “Functional
Olive Oils: scientific basis for their production. Evaluation of the antioxidant
/antiatherosclerotic/anticancer activity of olive oil polyphenols”
Coinvestigator of the project funded by CAPES/CPLP-4.1.3:“Molecular
hybridization in the development of anticancer agents”
Coinvestigator of the project funded by Portugal-Spain Integrated Actions:
“Protective role of adenosine in inflammatory processes: development of new
therapeutic strategies- University Vigo and University Porto.
“Determination of the antioxidant efficiency and distribution in model food emulsions.
University Vigo and University Porto
Prizes:“Fundação Eng.º António de Almeida, 1982”; Prémio “Nuno Salgueiro”; Prize
DAC/FECS Analítica 2001 (Sociedade Portuguesa de Química-Divisão de Química
Analítica), Prize Radicais Livres em Química, Biologia e Medicina 2001 (Sociedades
Portuguesa de Química e Bioquímica), Prize Projecto do Ano 2002 (Programa
Sócrates/Erasmus); Prize “Spectro Analytical Instruments” 2006; Prize of the best
communication 2006 on the IV Congresso Ibérico de Espectroscopia/XX Reunión
Española de Espectroscopía).
Offices: Member of Executive Committee of School of Pharmacy, University of Porto
(1990 – 1993); Member of Pedagogic Council of School of Pharmacy, University of
Porto (1988 – 1990); Member of Scientific Council of School of Pharmacy, University
of Porto (1995 –…); Coordinator of Socrates/Erasmus (1998-…) and Leonardo da
Vinci Programs (1998-2000); Coordinator of the International Office of the School of
Pharmacy, University of Porto (2000-2007)
Research Interests: Design and synthesis of bioactive phenolic compounds as
potential antioxidants and/or anticancer agents. Synthesis of metabolites. SAR, SPAR,
QSAR, QSTR, QSMR and mechanistic studies. Studies of the oxidative behaviour of
drugs. Identification and quantification of the compounds resulting from drug
degradation processes. Screening of biologic activity.
Memberships: Sociedade Portuguesa de Química; Sociedade Portuguesa de
Bioquímica; Sociedade Portuguesa de Farmacologia; Sociedade Portuguesa de Ciências
Farmacêuticas; “Oxygen Society” - International Society for Free Radical Research
Referee of the following Journals: Journal Agricultural Food Chemistry; Current
Medicinal Chemistry; Journal Medicinal Chemistry; European Journal Medicinal
Chemistry; Bioorganic Medicinal Chemistry; Bioorganic Medicinal Chemistry Letters;
Archives der Pharmazie; Resonance Magnetic Chemistry; Structural Chemistry
Abstract Reviewer” of the Society for Free Radical Biology and Medicine
(SFRM);Talanta; Analytica Chimica Acta
Expert evaluator of FP7 Program – Marie Curie Actions
Original Publications in English in Peer-Reviewed Journals: 70
Original Publications in Portuguese in Peer-Reviewed Journals: 3
Oral communications to International and National congresses: 27
Communications to International and National congresses: 230
Book chapters: 3 (one of the Royal Society Chemistry and other of the American
Chemical Society)
Number of PhD Thesis guided: 6
Number of Master Thesis (National and in Europe) guided: 7
Number of Degree Thesis (National and in Europe) guided: 6
Patents: 1 and 3 submitted
Organization of Congresses, Meetings and Conferences
Member of the Organizing Comitee of the I Encontro de Estudantes Sócrates e
Leonardo da Vinci da FFUP, 30 July, 2001.
President and member of the Scientific and Organizing Comittee of 5º Congresso de
Radicais Livres em Química, Biologia e Medicina (Sociedade Portuguesa de Química e
Sociedade Portuguesa de Bioquímica), Faculdade de Farmácia da Universidade do
Porto, 13-15 December, 2001.
Member of the Organizing Comitee of the meeting“Um milhão de Erasmus na Europa
em 15 anos - Universidade do Porto”, Serviço de Relações Internacionais da
Universidade do Porto, 18 October, 2002.
Coordenator of the course “Espectroscopia e Espectrometria” Faculdade de Farmácia
do Porto, 23, 24, 29 e 30 de April, 2003.
President and member of the Scientific and Organizing Comittee of the First Iberic
Meeting on Medicinal Chemistry: Anticancer Agents, Régua, Portugal, 28 de April a 1
de Maio, 2007.
Chairman on the following congresses/meetings:
XII Encontro Luso-Galego de Química, Exponor-Feira Internacional do Porto,
Portugal, 11-13 November, 1998.
COST Action 922 (cooperation in Science and Technology) “Health Implications of
Dietary Amines” Coimbra, Portugal, 3-6 Novemberde 2005
IV CIE (IV Congresso Ibérico de Espectroscopia/XX Reunión Española de
Espectroscopía), 10 a 14 September de 2006, Ciudad Real, Spain
National and International Collaborations: University of Porto; University of
Aveiro; University of Coimbra; University of Minho; University of Texas (Austin,
EUA) University of Santiago Compostela (Spain); University of Vigo (Spain);
University Cagliari (Italy); University of Rome “Tor Vergata” (Italy);University of
Rome “La Sapienza” (Italy); University of Rennes (France); University Central of “las
Villas” (Cuba).