Curriculum vitae
Rui Manuel Santos Malhó
1. Dados pessoais
Nome completo
Rui Manuel Santos Malhó
Data de nascimento
05-03-1967
País de nacionalidade
Portugal
Sexo
M
Morada institucional
Faculdade de Ciências da Universidade de Lisboa
Dept Biologia Vegetal, Fac Ciências Lisboa, Campo Grande
1749-016 Lisboa
Portugal
Telefone instituição
217500069
Email
[email protected]
Fax
217500048
2. Formação académica
Ano: 1995
Grau: DOUTORAMENTO
Classificação: Muito bom com distinção e Louvor
Instituição que conferiu o grau: Universidade de Lisboa
Faculdade: Faculdade de Ciências
Título da tese: Estudo da germinação do grão de pólen - Factores influenciantes do
alongamento e crescimento orientado do tubo polínico
Orientador: A.J. Trewavas
Co-orientador: M.S. Pais
Domínio científico: Biologia Celular
Designação do curso: Doutoramento em Biologia
Ano: 2001
Grau: AGREGAÇÃO
Classificação: Aprovado por unanimidade
Instituição que conferiu o grau: Universidade de Lisboa
Faculdade: Faculdade de Ciências
Título da tese:
Orientador:
Co-orientador:
Domínio científico:
Designação do curso:
3. Actividades anteriores e situação actual
Período
Cargo, categoria ou actividade
Instituição
a Prof Associado com Agregação
Faculdade de Ciências de Lisboa
a Prof Auxiliar com Agregação
Faculdade de Ciências de Lisboa
a Professor Auxiliar
Faculdade de Ciências de Lisboa
a Assistente
Faculdade de Ciências de Lisboa
a Assistente estagiário
Faculdade de Ciências de Lisboa
4. Área de actividade científica
Cell & Molecular Biology
Functional Genomics
Microscopy
5. Domínio de especialização
Domínio de especialização
Cell & Molecular Biology
Actuais interesses de investigação
Cell & molecular biology (signal perception and transduction; membrane trafficking)
Functional Genomics (molecular constructs, gene function, protein activity and
localization)
Fluorescence video and confocal microscopy
Plant Cell development
Human gene disorders
Outras competências/actividades
Biotechnology
6. Experiência na orientação
Orientações de Pós-Doutoramento concluídas: 5
Orientações de Pós-Doutoramento em curso: 2
Orientações de Doutoramento concluídas: 10
Orientações de Doutoramento em curso (interno): 1
Orientações de Doutoramento em curso (externo): 0
Orientações de Mestrado em curso (externo): 0
Orientações de Mestrado em curso (interno): 0
Orientações de Estágios Profissionalizantes: 10
Orientações de Estágios Educacionais: 2
Orientações de bolseiros de investigação: 5
7. Participação em projectos
Participação em projectos de investigação (coordenador/membro de equipas)
Coordinator:
Caracterização das bases moleculares do direccionamento de células com crescimento
polarizado. JNICT, 1996-1998.
Study of the biochemical and molecular mechanisms involved in the control of
polarized cells oriented growth. EU (PTP). Abril-Julho 1996.
Estudos dos mecanismos bioquímicos e moleculares envolvidos no direccionamento de
células com crescimento polarizado. Praxis XXI, 1996-1998.
Study of the molecular mechanisms involved in cell orientation - Identification of
calmodulin binding proteins responsible for controlling pollen tube orientation. EU, DG
XII. Abril 97 - Abril 98.
Signal transduction mechanisms controlling pollen tube morphogenesis and orientation.
HFSP, 1998-2001.
Mechanisms for pollen tube guidance - a biochemical and molecular study towards the
understanding of plant fertilisation. Praxis XXI, 1999-2001.
Signal transduction mechanisms controlling pollen tube growth and orientation – the
role of Rho/Rop proteins. FCT, 2000 - 2003.
Molecular and Cellular Mechanisms of tip growth in plant cells - TIPNET. EU (TMR)
2002-2004.
Signal transduction mechanisms controlling pollen tube morphogenesis and orientation.
FCT, 2002-2004.
Relationship between phosphatidic acid and calcium during polarity induction in tip
growing systems. GRICES/DAAD, 2003-2004.
Mecanismos de transdução de sinal no crescimento de tubos polínicos - caracterização
de uma via de AMPc em células vegetais. FCT, 2003-2005.
Signal transduction mechanisms in polarized cells – the role of phosphoinositides and
phospholipids. FCT, 2005-2007.
“Regulatory mechanisms of signalling cascades in apical growing cells – crosstalk
between actin dynamics and modulation of ion levels”. FCT (Ciências Agronómicas e
Florestais), 2010 - 2012.
Partner:
Estudo do papel do Ca2+ citossólico no controlo do crescimento polarizado dos tubos
polínicos. JNICT, 1993,1994.
Estudo dos mecanimos envolvidos no controlo do direccionamento de células com
crescimento polarizado. JNICT/BC, 1995.
Identificação e caracterização de sequências de DNA/domínios cromossómicos
envolvidos na modificação dos padrões de crossing-over (PI Prof L Morais, ISA). FCT,
2000-2003.
Impacto ecológico e populacional da apanha comercial de algas agarófitas (PI Prof R
Melo, DBV, FCL). PDCTM, 2000-2003.
Study of signalling and signal transduction processes in organogenic studies (PI Prof
M.S. Pais, DBV, FCL). FCT, 2000-2003.
Intracellular immunization for AIDS therapy: targeting HIV infectivity (PI Prof J
Gonçalves, FFUL). FCT, 2000-2003.
Biogenesis and function of CFTR protein with different mutations (PI Prof M Amaral,
DQB, FCUL). FCT, 2001-2003.
Monitoring of Concentration Boundary Layers by Confocal Microscopy (PI Prof J
Crespo, IBET). FCT, 2002-2003.
Arabidopsis thaliana as a model to analyse genetic controls of chromatin topology:
effects on gene expression and homologous recombination (PI Prof N Neves, ISA).
FCT, 2002-2004.
Isolation, cloning and functional definition of salt tolerance genes of Populus euphratica
by comparative genomic approaches (PI Dr G Ruisheng). FCT, 2002-2004.
Regulatory mechanisms of membrane trafficking in plants: role of myosins in plant
development. FCT, 2005-2007.
Biological role of arabinogalactan proteins and glycosylphosphatidylinositol anchoring
in Arabidopsis gametogenesis (PI Prof S Coimbra, UP). FCT 2008-2010.
“Transcript and metabolic responses associated with susceptibility of Trincadeira
grapes to Botrytis cinerea. Impact on regular ripening and flavour development" (em
colaboração com Doutora Ana M Fortes, ICAT-FCUL). FCT (Ciências Agronómicas e
Florestais - Genómica de Plantas), 2010-2012.
“Regulatory mechanisms of signalling cascades in apical growing cells – crosstalk
between actin dynamics and modulation of ion levels”. FCT (Ciências Agronómicas e
Florestais), 2010 - 2012.
8. Prémios e Distinções
Ano
Prémio ou distinção
Entidade promotora
2014
Index H = 27
WOK
2014
Citações em WOK
2565 citations (book chapters not included)
2007
Membro (correspondente) da Academia de Ciências (Ciências Biológicas).
Academia de Ciências de Lisboa
1999
2nd Best Poster
“Pollen-Stigma Interactions”, Oxford meeting
1996
Best oral presentation
XIV congresso internacional “Sexual Reproduction in Plants”
9. Publications
Teses
“Estudo da germinação do grão de pólen - Factores influenciantes do alongamento e
crescimento orientado do tubo polínico”
Livros (editor)
The Pollen tube – A Cellular and Molecular Perspective. Ed Rui Malhó, SpringerVerlag 2006, ISBN 3-540-31121-1
Capítulos de livros
1. Malhó R. (1998) The role of calcium and associated proteins in tip growth and
orientation. In: Fertilization in higher plants. Molecular and Ctyological Aspects. Eds
M. Cresti, G. Cai and A. Moscatelli. Springer-Verlag. Pp 253-270. (manuscripto
efectuado a convite)
2. Malhó R. (2000) Coding information in plant cells using Ca2+ as a second
messenger - The cell as the minimum unity for complexity. “Advanced Studies in Plant
Biology” - Integrated Plant Systems, Universidade de Geneva. Eds. H. Greppin, C
Penel & R. Degli Agosti. Pp 311-339 (manuscripto efectuado a convite)
3. Malhó R., Moutinho A. (2001) A cAMP pathway in pollen tube growth and
reorientation. In: Cell Biology of Plant and Fungal Tip Growth. NATO ASI Series vol
328. Eds A. Geitmann, M. Cresti and I.B.Heath. Pp 95-104 (manuscripto efectuado a
convite)
4. Malhó R., Camacho L., Moutinho, A. (2002) Imaging ions and molecules in living
plant cells. In: Molecular Plant Biology Volume two: A practical approach. Eds P.
Gilmartin & C. Bowler. Oxford Univ. Press. ISBN 0-19-963818-7
5. Malhó R., Camacho L. (2002) Ca2+ signalling systems in plants. The cell as the
minimum unity for complexity. In: "ADVANCES IN PLANT PHYSIOLOGY",
Volume 4. Eds. Hemantaranjan A. Institute of Agricultural Sciences, Varanasi, India.
Pp 179-203 (manuscripto efectuado a convite)
6. Malhó R., Camacho L. (2004) Signalling the cytoskeleton in pollen tube germination
and growth. In: The Plant Cytoskeleton in Cell Differentiation and Development. Eds.
Hussey P.J., Ann. Plant Review Series, Blackwell Publishers, UK. Pp 240-264.
7. Malhó R., Castanho Coelho P., Pierson E., Derksen J. (2005) Endocytosis and
membrane recycling in pollen tubes. In: The Plant Endocytosis. Eds. Samaj, J., Baluska,
F., Menzel, D., Springer-Verlag, Germany. Pp 277-291.
Artigos em revistas de circulação internacional com arbitragem científica
1. Malhó R., Feijó J.A., Pais M.S. (1992) Effect of electrical fields and external ionic
currents on pollen tube orientation. Sexual Plant Reproduction. 5: 57-63
2. Malhó R., Pais M.S. (1992) Kinetics and Hydrodynamics of Agapanthus umbellatus
Pollen Tube. A structural and stereological Study. Sexual Plant Reproduction. 5: 163168.
3. Feijó J.A., Malhó R., Pais M.S. (1992) A cytochemical study on the role of ATPases
during pollen germination in Agapanthus umbellatus L´Her. Sexual Plant Reproduction.
5: 138-145.
4. Read N.D., Allan W.T.G., Knight H., Knight M.R., Malhó R., Rusell A., Shacklock
P., Trewavas A.J. (1992) Imaging and measurement of cytosolic free calcium in plant
and fungal cells. J. Microscopy 165: 586-616.
5. Malhó R., Read N., Pais M.S., Trewavas A.J. (1994) Role of cytosolic free calcium
in the reorientation of pollen tube growth. The Plant Journal 5: 331-341.
6. Malhó R., Read N., Trewavas A.J., Pais M.S. (1995) Calcium channel activity during
pollen tube growth and reorientation. The Plant Cell. 7: 1173-1184.
7. Feijó J.A., Malhó R., Obermeyer G. (1995) Ion dynamics and its possible role during
in vitro pollen germination and tube growth. Protoplasma. 187: 155-167.
8. Malhó R., Trewavas A.J. (1996) Localized Apical Increases of Cytosolic Free
Calcium Control Pollen Tube Orientation. The Plant Cell. 8: 1935-1949.
9. Parton R., Fischer S., Malhó R., Papasouliotis O., Jelitto T., Leonard T., Read N.
(1997) Pronounced gradients in cytoplasmic pH are not required for tip growth in plant
and fungal cells. J. Cell Sci. 110: 1187-1198.
10. Trewavas A.J., Malhó R. (1997) Signal perception and transduction. The origin of
the phenotype. (manuscripto efectuado a convite) The Plant Cell. 9: 1181-1195.
11. Malhó R. (1998) Expanding tip-growth theory. Trends in Plant Science. 3: 40-42.
(manuscripto efectuado a convite)
12. Malhó R. (1998) Role of 1,4,5-Inositol Triphosphate-Induced Ca2+ Release in
Pollen Tube Orientation. Sex. Plant Reprod. 11: 231-235
13. Malhó R. (1998) Pollen Tube Guidance: the long and winding road. Sex. Plant
Reprod. 11: 242-244 (manuscripto efectuado a convite)
14. Malhó R., Moutinho A., Van der Luit A., Trewavas A.J. (1998) Spatial
characteristics of Ca2+ signalling; the calcium wave as a basic unit in plant cell calcium
signalling. Phil. Trans. R. Soc. B 353, 1463-1473.
15. Moutinho A., Love J., Trewavas A.J., R. Malhó R. (1998) Distribution of
Calmodulin Protein and mRNA in Growing Pollen Tubes. Sex. Plant Reprod. 11: 131139.
16. Moutinho A., Trewavas A.J., Malhó R. (1998) Relocation of a Ca2+-Dependent
Protein Kinase activity during Pollen Tube Reorientation. Plant Cell. 10: 1499-1510.
17. Penque D., Gomes A., Mock M., Farinha C., Malhó R., Demolombe S., Escande D.,
Lavinha J., Amaral M.D. (1998) Cystic Fibrosis: cellular characterization of A561E
Portuguese mutation. Eur. J. Hum. Gen. 6(S1): P5016.
18. Trewavas A.J., Malhó R. (1998) Ca2+ Signalling in plant cells: the big network.
Curr. Op. Pl. Biol. 1: 428-433 (manuscripto efectuado a convite)
19. Malhó R. (1999) Coding information in plant cells: the multiple roles of Ca2+ as a
second messenger. Plant Biol. 1: 487-494.
20. Malhó R. Camacho L., Moutinho, A. (2000) Signaling pathways in pollen tube
growth and reorientation. Annals of Botany. 85 (suppl A): 59-68
21. Camacho L., Parton R.M., Trewavas A.J., Malhó R. (2000) Imaging [Ca2+]c
distribution and oscillations in pollen tubes with confocal microscopy. A comparison of
different dyes and loading methods. Protoplasma.212: 162-173
22. Xavier, J.B., Malhó, R., Reis, A.M., Almeida, J.S. (2000) Description of Biofilm
Formation by Determination of Developmental Axis. Water Science and Technology.
41: 121-127
23. Penque D., Mendes F., Beck S., Farinha C., Pacheco P., Nogueira P., Lavinha J.,
Malhó R., Amaral M.D. (2000) Cystic Fibrosis F508del-patients have apically localized
CFTR in a reduced number of airway cells. Laboratory Investigation. 80: 857-868.
24. de Ruitjer N., Malhó R. (2000) Plant and fungal tip growth: where do we go from
here ? Trends in Plant Science. 5: 453-454 (manuscripto efectuado a convite)
25. Moutinho A., Camacho L., Haley A., Pais M.S., Trewavas A.J., Malhó R. (2001)
Antisense suppression of protein function in living pollen tubes. Sex. Plant Reprod. 14:
101-104.
26. Moutinho A., Hussey P., Trewavas A.J., Malhó R. (2001) The role of cAMP and
adenylate cyclase in pollen tube growth and reorientation. Proc. Natl. Acad. Sci. USA
98: 10481-10486.
27. Trewavas A.J., Rodrigues C., Rato C., Malhó R. (2002) Cyclic nucleotides: the
current dilemma! Curr. Op. Plant Biol. 5: 425-429.
28. Caperta A., Neves N., Morais-Cecílio L., Malhó R., Viegas W. (2002) Genome
restructuring in rye affects the expression, organization and disposition of homologous
rDNA loci. J. Cell Sci. 115: 2839-2846.
29. Gonçalves J., Silva F., Freitas-Vieira A., Santa-Marta M., Malhó R., Yang, X.,
Gabuzda D., Barbas III C. (2002) Functional neutralization of HIV-1 Vif protein by
intracellular immunization inhibits reverse transcription and viral replication. J. Biol.
Chem. 277: 32036-32045.
30. Camacho L., Malhó R. (2003) Endo-exocytosis in the pollen tube apex is
differentially regulated by Ca2+ and GTPases. J. Exptl. Bot. 54: 83-92.
31. D’Angeli S., Malhó R., Altamura M.M. (2003) Low temperature sensing by olive
tree: calcium signaling and cold acclimation. Plant Sci. 165: 1303-1313.
32. Carvalho-Oliveira I., Efthymiadou A., Malhó R., Tzetis M., Kanavakis E., Amaral
M.D., Penque M.D. (2003) CFTR Localization in Native Airway Cells and Cell Lines
Expressing Wild-type or F508del-CFTR by a Panel of Different Antibodies. J.
Histochem. Cytochem. 52: 193-204.
33. Rato C., Monteiro D., Hepler P.K., Malhó R. (2004) Calmodulin activity and cAMP
signalling modulate growth and apical secretion in pollen tubes. The Plant Journal. 38:
887-897.
34. Deeks M.J., Kaloriti D., Davies B., Malhó R., Hussey P.J. (2004) Arabidopsis
NAP1 Is Essential for Arp2/3-Dependent Trichome Morphogenesis. Current Biology.
14: 1410-1414.
35. Malhó R., Liu Q., Monteiro D., Rato C., Camacho L., Dinis A. (2006) Signalling
pathways in pollen germination and tube growth. Protoplasma, 228:21-30.
36. Monteiro D., Castanho Coelho P., Rodrigues C, Camacho L., Quader H., Malhó, R.
(2005) Modulation of endocytosis in pollen tube growth by phosphoinositides and
phospholipids. Protoplasma. 226: 31-38.
37. Monteiro D., Liu Q., Lisboa S., Scherer G.E.F., Quader H., Malhó R. (2005)
Phosphoinositides and phosphatidic acid regulate pollen tube growth and reorientation
through modulation of [Ca2+]c, and membrane secretion. J. Exptl. Bot. 56: 1665-1674
38. Zheng H., Camacho L., Batoko H., Wee E., Legen J., Leaver C., Malhó, R., Hussey
P., Moore I. (2005) A RabE GTPase mutant acts downstream of the RabD subclass in
biosynthetic membrane traffic to the plasma membrane. Plant Cell. 17: 2020-2036
39. Fortes A.M., Miersch O., Malhó R., Testillano P.S., Serrano J.S., Risueño M.C.,
Wasternack C., Pais M.S. (2005) Transient expression of allene oxide cyclase and
transient accumulation of jasmonic acid and 12-oxophytodienoic acid occurs during
organogenic nodule formation from hop (Humulus lupulus var. Nugget) internodes.
Plant & Cell Physiol. 46: 1713-1723
40. Castanho Coelho P., Malhó, R. (2006) Correlative analysis of apical secretion and
[Ca2+]C in pollen tube growth and reorientation. Plant Signaling & Behavior. 1: 152157
41. Malhó R., Kaloriti D., Sousa E. (2006) Calcium and rhythms in plant cells. In:
Biological Rhythms Research – Plant Chronobiology. Eds. Waterhouse J., Wagner E.,
Rietveld, W. Vol 37: 297-314.
42. Marques L., Banha J., Penque D., Barreto M., Malhó R., Costa L. (2007)
Ceruloplasmin and ferroportin are expressed at the surface of human peripheral blood
lymphocytes. Amer. J. Hematology 82: 549-549.
43. Rodrigues* C., Deeks* M.J., Dimmock S., Ketelaar T., Maciver, S.K., Malhó R.,
Hussey P.J. (2007) Arabidopsis CAP1, a key regulator of actin organisation and
development. (*)contribuição identical na autoria. J. Cell Sci. 120: 2609-2618
44. Garcês H.M.P., Champagne C.E.M., Townsley B.T., Park S., Malhó R., Pedroso
M.C., Harada J.J., Sinha N.R. (2007) Evolution of asexual reproduction in leaves of the
genus Kalanchoë. Proc. Natl. Acad. Sci. USA 104: 15578-15583
45. Banha J., Marques L., Oliveira R., Paixão E., Martins M.F., Malhó R., Penque D.,
Costa L. (2008) Ceruloplasmin expression by human peripheral blood lymphocytes: a
new link between immunity and iron metabolism. Free Radical Biol & Medicine 44:
483-492
46. Fortes A.M., Santos F., Figueiredo A., Choi Y., Silva M.S., Sousa L., Pessoa F.,
Acioli B., Sebastiana M., Palme K., Malhó R., Verpoorte R., Pais M.S. (2008)
Transcriptional and metabolic profiling during organogenic nodule formation in hop.
BMC Genomics 9: 445
47. Sousa E., Kost B., Malhó R. (2008) Arabidopsis Phosphatidylinositol-4Monophosphate 5-Kinase 4 regulates pollen tube growth and polarity by modulating
membrane recycling. Plant Cell 20: 3050-3064
48. Pedroso N., Matias A.C., Cyrnea L., Antunes F., Borges C., Malhó R., Almeida
R.F.M, Herrero E., Marinho H.S. (2009) Modulation of plasma membrane lipid profile
and microdomains by H2O2 in Saccharomyces cerevisiae. Free Radical Biol &
Medicine. 46: 289-298
49. Ângelo Silva P., Rehman R., Rato C., Di Sansebastiano G-P., Malhó R. (2010)
Asymmetric localization of Arabidopsis syntaxins at the pollen tube apical and subapical zones is involved in tip growth. BMC Plant Biol. 10: 179
50. Santos R., Miguel S., Malhó R., Maycock C., Fevereiro P., Oliva A. (2010) The
impact of CdSe/ZnS Quantum Dots in cells of Medicago sativa in suspension culture.
Journal of Nanobiotechnology 8:24
51. Rehman R., Ângelo Silva P., Malhó R. (2011) Localization of Arabidopsis SYP125
syntaxin in the plasma membrane sub-apical and distal zones of growing pollen tubes.
Plant Sig. & Behav 6(5): 665-670
52. Saavedra L., Mikami K., Malhó R., Sommarin M. (2012) PIP kinases and their role
in plant tip growing cells. Plant Signalling & Behavior 7(10): 1302-1305. DOI:
10.4161/psb.21547
53. Aires da Silva F., Li, M., Rato, S., Maia S., Malhó R., Warren, K., Harrich, D.,
Craigie R., Barbas III C., Goncalves J. (2012) Recombinant rabbit single-chain
antibodies simultaneously bind to the catalytic and C-terminal domains of HIV-1
integrase protein and strongly inhibit HIV-1 infection. Biotechnology and Applied
Biochemistry 59: 353-366. DOI: 10.1002/bab.1034
54. Silva, S., Alves, A.C.S., Patel, D., Malhó, R., Soutar, A.K., Bourbon, M. (2012) In
vitro functional characterization of missense mutations in the LDLR gene.
Atherosclerosis. 225: 128-134. DOI: 10.1016/j.atherosclerosis.2012.08.017
55. Tunc-Ozdemir*, M., Rato*, C., Brown, E., Rogers, S., Goyne, A., Frietsch, S.,
Myers, C.T., Poulsen, L.R., Malhó, R., Harper, J.F. (2013) Cyclic nucleotide gated
channels 7 and 8 are essential for male reproductive fertility. (*) contribuição identical
na autoria. PLoS One. 8(2):e55277. doi: 10.1371/journal.pone.0055277.
56. Serrazina, S., Vaz Dias, F., Malhó R. (2014) Characterization of FAB1
phosphatidylinositol kinases in Arabidopsis pollen tube growth and fertilization. New
Phytologist. DOI: 10.1111/nph.12836
Publicações em actas de encontros científicos
1. Penque D., Gomes A., Mock M., Farinha C., Malhó R., Demolombe S., Escande D.,
Lavinha J., Amaral M.D. (1998) Cystic Fibrosis: cellular characterization of A561E
Portuguese mutation. Eur. J. Hum. Gen. 6(S1): P5016.
2. Gonçalves J., Silva F., Freitas-Vieira A., Santa-Marta M., Malhó R., Yang, X.,
Gabuzda D., Barbas III C. (2002) Functional neutralization of HIV-1 Vif protein by
intracellular immunization inhibits viral replication. XIV international aids conference:
basic sciences pp 219-226
3. Costa M.J.L., Malhó R, Goncalves J., Ferreia G.N.M., Aires-Barros M.R. (2005)
Development of a 293t cell line for the production of virus like particles in bioreactors.
Animal Cell Technology Meets Genomics. 18th Meeting of the European-Society-ofAnimal-Cell-Technology (ESACT). Springer-Verlag.
4. Deeks M.J., Kaloriti D., Machesky L.M., Malhó R., Davies, B., Hussey P.J. (2005)
Actin nucleators in plants. Comparative biochemistry and physiology 141(3): S320S321
5. R. Malhó, P. Castanho Coelho, M. Ovecka, I. Lichtscheidl (2005) Structural and
dynamic aspects of pollen tube guidance: can actin deliver? Comparative biochemistry
and physiology 141(3): S324-S324
10. Comunicações
Comunicações orais por convite
1 Malhó & Feijó (1993) Mestrado em Biofísica e Neurobiologia, FCL, Lisboa.
2 Malhó et al. (1996) XIV congresso Internacional sobre "Sexual Plant Reproduction".
Lorne, Austrália
3 Malhó (1997) Mestrado em Biofísica e Neurobiologia, FCL, Lisboa.
4 Malhó (1997) Dept. of Plant Biology, Universidade de Budapeste
5 Malhó (1997) “Sexual Plant Reproduction and Biotechnological Applications: recent
advances by molecular biology, biochemistry and morphology”, Dept. of Biologia
Ambientale, Universidade de Siena
6 Malhó et al. (1997) XXXII Reunião Anual da Sociedade Portuguesa de Microscopia
Electrónica-Biologia Celular. Coimbra
7 Malhó (1998) “workshop” sobre Microscopia Confocal (Bio-Rad), IBILI, Coimbra
8 Malhó (1998) Dept. of Plant Biology, Universidade de York.
9 Malhó (1999) Workshop “Divulgação Científica. FCL (Nebulis)
10 Malhó (1999) IV Jornadas de Biologia do Desenvolvimento. Universidade
Lusófona, Lisboa
11 Malhó et al. (1999) “International Conference on Pollen-Stigma Interaction”, Oxford
12 Malhó (2000) Workshop “Advanced Studies in Plant Biology”, Universidade de
Geneva, Suiça
13 Malhó (2000) Dept. of Plant Biology, Universidade de Dublin.
14 Malhó (2000) NATO ASI course sobre “Advanced Research Workshop on Tip
growth”. Siena, Itália
15 Malhó (2000) Dept. of Plant Biology, Universidade de Roma.
16 Malhó (2000) Workshop “Ferramentas para Divulgação Científica. FCL
17 Malhó (2000) V Jornadas de Biologia do Desenvolvimento. Universidade Lusófona,
Lisboa
18 Malhó (2000) “Frontiers in Sexual Plant Reproduction”, Univ of New York at
Albany, USA
19 Malhó (2001) Workshop "Tip growth of plant cells". Viena
20 Malhó (2001) Workshop “Plant Development”, IGC, Oeiras
21 Malhó (2001) Dept. Biologie Cellulaire et Moleculaire, Universidade de Versailles.
22 Malhó (2001) XIV Reunión de la SEFC y VII Congresso Hispano-Luso de
Fisiologia Vegetal. Badajoz
23 Malhó (2001) Universidade de Hamburgo.
24 Malhó (2002) FCTUNL, Costa da Caparica
25 Malhó & Camacho (2002) “Annual Meeting of the Society for Experimental
Biology”, Swansea UK
26 Malhó (2002) VI ENEB. FCL
27 Malhó (2002) VI Congresso da "European Association of University Departments
and Faculties of Biology". FCL
28 Malhó & Camacho (2002) 13ª colóquio sobres “Canaux Ioniques", Presqu´ile de
Giens, França
29 Malhó (2002) FML, Mestrado de Neurociências
30 Malhó & Camacho (2002) IBMC, Porto
31 Rato, Monteiro, Rodrigues, Liu & Malhó (2003) “XI International Conference on
Plant Embryology”. Brno, Rep Checa
32 Malhó (2003) Universidade Lusófona
33 Malhó (2003) FML (Mestrado de Neurociências)
34 Rato, Monteiro, Liu & Malhó (2004) XI Intl Palynologycal Congress, Granada,
Espanha
35 Rato, Monteiro, Liu & Malhó (2004) "Endocytosis in Plants and Fungi", Heidelberg,
Alemanha
36 Malhó (2004) Frontiers in Sex. Plant Reprod. Albany, EUA.
37. R. Malhó, P. Castanho Coelho, M. Ovecka, I. Lichtscheidl (2005) Structural and
dynamic aspects of pollen tube guidance: can actin deliver? “SEB at Barcelona”, July
2005.
38. R. Malhó (2005) Pollen tube growth and guidance: [Ca2+]c is a key element in the
crosstalk of signaling pathways which modulate apical secretion. “XVII IBC”, Viena,
July 2005.
39. R. Malhó (2006) The Use of GFP and Molecular constructs in Plant Biotechnology.
“Jornadas de Engenharia Biológica da Universidade do Algarve”, Faro, Março 2006.
40. R. Malhó (2006) Studying Plant Cell Signalling with Live Microscopy tools. “XLI
reunião da Soc. Portuguesa de Microscopia”, Braga, Dezembro 2006.
41. R. Malhó (2006) Studying Plant Cell Signalling with Live Microscopy tools.
“Microscopy Autumn School”, Sociedade Italiana de Botânica, Sabaudia, Outubro
2006.
42. R. Malhó, E. Sousa (2006) Studying Plant Cell Signalling with Live Microscopy
tools. Conferência (plenária) apresentada a convite na “XLI reunião da Soc. Portuguesa
de Microscopia”, Braga, Dezembro 2006.
43. R. Malhó, E. Sousa (2007) The role of phosphoinositides in plant and pollen
development – a genetical, molecular and cellular analysis. Conferência (plenária)
apresentada a convite na “XX Reunión de la SEFV y X Congresso Hispano-Luso de
Fisiologia Vegetal”, Universidade de Alcalá de Henares, Setembro 2007, Madrid,
Espanha.
44. R. Malhó (2011) Science and Art: are creativity and rigor in opposite corners?
Palestra apresentada no “International Colloquim Science and Art”, Lisboa, 17-19
Fevereiro 2011.
45. R. Malhó (2011) Food and Agriculture – A Functional Genomics Approach.
Comunicação oral apresentada no “Food and Agriculture” COST Meeting, February
24-25, 2011, Algarve.
46. R. Malhó (2011) Oscillatory behavior in Biology versus Economics – relevant
similarities? Pre-Conference on Interdisciplinary perspectives on the global financial
crisis. NOVA School of Business and Economics. Lisboa, 30 May.
47. R. Malhó (2012) O erro e a importância do erro na investigação biológica.
Comunicação apresentada à Academia das Ciências de Lisboa, 5 Janeiro 2012.
48. A. P. Rauter, R. Malhó, T. Fernandes, J. B. Macedo (2013) Fórum para a
Valorização Social e Económica de Plantas Endémicas: Biodiversidade e Novas
Perspetivas. Comunicação apresentada no “XXIII Encontro da Associação das
Universidades de Língua Portuguesa (AULP)” Belo Horizonte, Brasil, Junho 2013.
Outras comunicações orais
1 Pais, Feijó and Malhó (1988) VII Simpósio de Palinologia. Granada
2 Malhó, Feijó & Pais (1989) XXIV Reunião da SPME. Coimbra
3 Malhó, Feijó & Pais (1989) XXIV Reunião da SPME. Coimbra
4 Pais, Malhó & Feijó (1990) VIII Simpósio de Palinologia. Canárias
5 Malhó, Feijó & Pais (1990) XIIth International Symposium on Embriology and Seed
Reproduction. Leninegrado, USSR
6 Malhó, Feijó & Pais (1990) XXV Reunião da SPME. Porto
7 Malhó et al (1992) XII congresso Internacional sobre "Sexual Plant Reproduction".
Columbus, Ohio
8 Malhó et al (1992) XXVII Reunião da SPME-BC. Oeiras
9 Malhó et al (1993) XXVIII Reunião da SPME-BC. Oeiras
10 Malhó et al (1993) XXVIII Reunião da SPME-BC. Oeiras
11 Malhó et al (1994) XIII congresso Internacional sobre "Sexual Plant Reproduction".
Wien, Austria.
12 Malhó et al (1994) XXIX Reunião da SPME-BC. Coimbra
13 Feijó et al (1994) XXIX Reunião da SPME-BC. Coimbra
14 Feijó et al (1994) XXIX Reunião da SPME-BC. Coimbra
15 Malhó et al (1995) V Encontro Internacional da “Royal Microscopical Society”.
Oxford
16 Parton et al (1995) V Encontro Internacional da “Royal Microscopical Society”
(Biologia celular em plantas). Oxford
17 Malhó et al (1995) XX Reunião da SPME-BC. Porto
18 Malhó (1995) XXX Reunião da SPME-BC. Porto
19 Moutinho et al (1997) XXXII Reunião da SPME-BC. Coimbra
20 Penque et al (1997) XXXII Reunião da SPME-BC. Coimbra
21 Moutinho et al (1998) XV congresso Internacional sobre "Sexual Plant
Reproduction". Wageningen, Holanda
22 Malhó et al (1998) XV congresso Internacional sobre "Sexual Plant Reproduction".
Wageningen, Holanda
23 Malhó et al (1998) XXXIII Reunião da SPME-BC. Porto
24 Moutinho et al (1998) XXXIII Reunião da SPME-BC. Porto
25 Camacho et al (1998) XXXIII Reunião da SPME-BC. Porto
26 Malhó et al (1999) VI Royal Botanical Microscopy Meeting. St Andrews, UK
27 Xavier et al (1999) 4th IAWQ Conference on Biofilm Systems, New York, USA
28 Xavier et al (1999) XXXIV Reunião da SPME-BC. Lisboa
29 Penque et al (1999) XXXIV Reunião da SPME-BC. Lisboa
30 Penque et al (1999) XXXIV Reunião da SPME-BC. Lisboa
31 Malhó et al (2000) XVI Congresso Internacional "Sexual Plant Reproduction".
Banff, Canadá
32 Moutinho et al (2000) XVI Congresso Internacional "Sexual Plant Reproduction".
Banff, Canadá
33 Penque et al (2000) “First consensus meeting towards validation of CFTR gene
expression and assays”, Carcavelos, Lisboa.
34 Malhó et al (2002) XVII Congresso Internacional "Sexual Plant Reproduction".
Lublin, Polónia
35 Malhó & Camacho (2002) XXXVII Reunião da SPME-BC. Funchal
36 Malhó & Camacho (2002) XXXVII Reunião da SPME-BC. Funchal
37 Rato & Malhó (2002) XXXVII Reunião da SPME-BC. Funchal
38 Camacho et al (2003) "7th International Botanical Microscopy Meeting". Lisboa
39 Malhó et al (2003) "7th International Botanical Microscopy Meeting". Lisboa
40 Moore et al (2003) "7th International Botanical Microscopy Meeting". Lisboa
41 Monteiro et al (2004) XXXIX reunião da SPME-BC, Aveiro
42 Rato et al (2004) XXXIX reunião da SPME-BC, Aveiro
43 Camacho et al (2004) XXXIX reunião da SPME-BC, Aveiro
44 D´Angeli et al (2004) XXXIX reunião da SPME-BC, Aveiro
45 Kaloriti et al (2004) XXXIX reunião da SPME-BC, Aveiro
46 M.J. Deeks, D. Kaloriti, L.M. Machesky, R. Malhó, B. Davies, P.J. Hussey (2005)
Actin nucleators in plants. “SEB at Barcelona”, July 2005.
47 A.M. Fortes, F. Santos, A. Figueiredo, Y. Choi, M. Silva, L. Sousa, B. Acioli, M.
Sebastiana, F. Pessoa, R. Malhó, R. Verpoorte, M.S. Pais (2006) Transcriptional and
metabolic profiling during organogenic nodule formation in hop.“Plant Genomics
European Meetings”, Venice, Italy, 11-14 October 2006.
48. R. Malhó (2010) The study of Cell Signalling and Morphogenesis with Live
Microscopy tools.
Comunicação oral apresentada na UAlg, 22 Janeiro 2010, Faro.
49. R. Malhó, Ângelo Silva P., Rehman R., Rato C., Di Sansebastiano G-P. (2010)
Asymmetric localization of syntaxins regulates exocytic domains at the pollen tube
apical zone. Comunicação oral apresentada no “XXI International Congress on Sexual
Plant Reproduction”, Bristol, Agosto 2010.
50. Bastos, A.E.P., Scolari, S., Herrmann, Malhó, R., Marinho, H.S., de Almeida,
R.F.M. (2011) Biophysical studies of ergosterol-containing membranes reveal new
important differences between yeast and mammalian lipid rafts. Comunicação oral
apresentada no 1º Encontro de alunos do DQB-FCUL, Lisboa, 7 de Junho.
51. R. Malhó, S. Serrazina, F. Vaz Dias (2011) Characterization of phosphatidylinositol
kinases in Arabidopsis pollen tube growth - a role in exocytosis and membrane
recycling. Comunicação oral apresentada no “Exocytosis in Animals, Fungi and Plants
2011 Soc. Exptl. Biology meeting”, Londres, 19-21 Setembro 2011.
52. S. Serrazina, F. Vaz Dias, R. Malhó (2013) Characterization of FAB1
phosphatidylinositol kinases in Arabidopsis pollen tube growth and fertilization.
Comunicação apresentada no “Annual Meeting of the Soc Exptl Biology - SEB”
Valência, Espanha, 2-6 Julho.
53. A. P. Rauter, R. Malhó, T. Fernandes, J. B. Macedo (2013) Fórum para a
Valorização Social e Económica de Plantas Endémicas: Biodiversidade e Novas
Perspetivas. Comunicação apresentada no “XXIII Encontro da Associação das
Universidades de Língua Portuguesa (AULP)” Belo Horizonte, Brasil, Junho 2013.
54. R. Malhó, F. Vaz Dias, S. Serrazina (2014) The role of Arabidopsis thaliana
phosphatidylinositol and lipid kinases, in pollen tube growth and fertilization: a cellular
and molecular analysis. Comunicação apresentada no XXIII “International Congress on
Sexual Plant Reproduction”, Porto, 13-18 Julho.
Comunicações em painel ("poster")
1. R. Malhó, J.A. Feijó & M. Salomé S. Pais (1990) "Biological Signal Transduction",
Grécia.
2. R. Malhó & M. Salomé S. Pais (1991) "Angiosperm Pollen and Ovules - Basic and
Applied Aspects". Itália.
3. R. Malhó, A. Moutinho, A.J. Trewavas & M.S. Pais (1997) “European Congress for
Cell and Molecular Biology”, Brighton, UK.
4. L. Camacho, A.J. Trewavas & Rui Malhó (1998) XV "Sexual Plant Reproduction".
Wageningen, Holanda.
5. J. Xavier, R. Malhó, A.M. Reis, J.S. Almeida (1998) “Ecologia Europaea Nº2”,
Strasbourg.
6. L. Camacho, A.J. Trewavas & Rui Malhó (1999) “VI Royal Botanical Microscopy
Meeting”. St Andrews, UK.
7. A. Moutinho, P. Hussey, A.J. Trewavas & R. Malhó (1999) “International
Conference on Pollen-Stigma Interaction”, Oxford.
8. J. Xavier, R. Malhó, A.M. Reis, J.S. Almeida (1999) “99th General Meeting of the
Amer. Soc. Microbiology”, Chicago, USA.
9. A. Moutinho, R. Malhó (1999) XXXIV Reunião Anual da Sociedade Portuguesa de
Microscopia Electrónica-Biologia Celular. Lisboa.
10. A. Moutinho, P. Hussey, A.J. Trewavas & R. Malhó (2000) XVI "Sexual Plant
Reproduction". Banff, Canadá.
11. Penque D., Mendes F., Beck S., Farinha C., Pacheco P., Nogueira P., Lavinha J.,
Malhó R., Amaral M.D. (2000) “XIIIth International Cystic fibrosis congress”,
Estocolmo, Suécia.
12. L. Camacho, R. Malhó, P.J. Hussey (2002) 55th Harden Conference "Dynamics of
Membrane Traffic". Ambleside, UK.
13. S. D´Angeli, R. Malhó, M.M. Altamura (2002) XIII Congresso Internacional da
"Federation of European Societies of Plant Physiology". Heraklion, Creta.
14. L. Camacho, M.J. Deeks, R. Malhó, P.J. Hussey (2002) BBSRC workshop
"Molecular motors: common themes from diverse systems. Univ of Warwick, UK.
15. S. Lisboa, D. Monteiro, Q. Liu, G.E.F. Scherer, H. Quader, R. Malhó (2003) "7th
International Botanical Microscopy Meeting". Lisboa.
16. C. Rato, D. Monteiro, R. Malhó (2003) "7th International Botanical Microscopy
Meeting". Lisboa.
17. F. Ressurreição, M. Delgado, A. Bexiga, L. Morais-Cecílio, R. Malhó, W. Viegas
(2003) "7th International Botanical Microscopy Meeting". Lisboa.
18. Santa-Marta M., Gil F., Malhó R., Gonçalves J. (2003) “Retroviruses meeting”.
Cold Spring Harbor, USA.
19. A.M. Fortes, O. Miersch, R. Malhó, P.S. Testillano, M.C. Risueño, J. SanchezSerrano, C. Wasternack, M.S. Pais (2003) “Plant Oxylipins”, Universidade de
Göttingen, Alemanha.
20. L. Camacho, M. Deeks, T. Ketelaar, R. Malhó, P.J. Hussey (2003) "Membrane
Trafficking in Plants". Univ of Glasgow, UK.
21. D. Monteiro, Q. Liu, S. Lisboa, G.E.F. Scherer, H. Quader, R. Malhó (2004)
"Frontiers in Sex. Plant Reprod.", Albany, USA.
22. Rato C., Monteiro D., Hepler P.K., Malhó R. (2004) "Frontiers in Sex. Plant
Reprod.", Albany, USA.
23. Monteiro et al (2004) XXXIX reunião da SPME-BC, Aveiro
24. M.J. Deeks, C. Rodrigues, D. Kaloriti, E. Allwood, T.J. Hawkins, Rui Malhó R.,
Hussey P.J. (2004) Signaling to the plant actin cytoskeleton. “FEBS Cytoskeletal
Dynamics”. Helsinquia, 12-16 Junho 2004.
25. D. Monteiro, Q. Liu, S. Lisboa, H. Quader, R. Malhó (2004) PIP2 and IP3 regulate
pollen tube growth and reorientation but caused different effects on [Ca2+]c, membrane
secretion and the actin cytoskeleton. “Frontiers in Sex. Plant Reprod. II”. Albany, 14-15
Outubro 2004.
26. C. Rato, D. Monteiro, P.K. Hepler, R. Malhó (2004) Calmodulin activity and cAMP
signalling modulate growth and apical secretion in pollen tubes. “Frontiers in Sex. Plant
Reprod. II”. Albany, 14-15 Outubro 2004.
27. D. Monteiro, Q. Liu, S. Lisboa, Castanho Coelho P, H. Quader, R. Malhó (2004)
Phosphatidic acid, a signalling phospholipid involved in pollen tube growth. “Frontiers
in Sex. Plant Reprod. II”. Albany, 14-15 Outubro 2004.
28. D. Monteiro, Q. Liu, S. Lisboa, Castanho Coelho P, H. Quader, R. Malhó (2004)
Ácido fosfatídico, um fosfolípido sinalizador envolvido no crescimento dos tubos
polínicos.
XXXIX reunião da SPME-BC, Aveiro, Novembro 2004.
29. C. Rodrigues, C. Rato, E. Sousa, P. Castanho Coelho, R. Malhó (2005) Crosstalk
between different signaling pathways in pollen tube growth and reorientation. “XVII
IBC”, Viena, July 2005.
30. L. Camacho, R. Malhó, P.J. Hussey (2005) Expression Program of the Myosin XI
Family in Arabidopsis thaliana.
“XVII IBC”, Viena, July 2005.
31. Ana M. Fortes, F. Santos, A. Figueiredo, B. Acioli, L. Sousa, M. Sebastiana, F.
Pessoa, M. Silva, R. Malhó, M.S. Pais (2006) Transcriptional profiling during
organogenic nodule formation in hop. European Plant Science Organisation 3rd EPSO
Conference “Plant Dynamics: from Molecules to Ecosystems”, Visegrád, Hungary 28
May – 1 June 2006.
32. A.M. Fortes, F. Santos, A. Figueiredo, Y. Choi, M. Silva, L. Sousa, B. Acioli, M.
Sebastiana, F. Pessoa, R. Malhó, R. Verpoorte, M.S. Pais (2006) Transcriptional and
metabolic profiling during organogenic nodule formation in hop. Poster apresentado no
meeting “Plant Genomics European Meetings”, Venice, Italy, 11-14 October 2006.
33. L. Marques, J. Banha, D. Penque, M. Barreto, R. Malhó, L. Costa (2007)
CERULOPLASMIN AND FERROPORTIN ARE EXPRESSED AT THE SURFACE
OF HUMAN PERIPHERAL BLOOD LYMPHOCYTES. Poster apresentado no
meeting da International BioIron Society (IBIS), Kyoto, 1-6 Abril 2007.
34. A.M Fortes, F. Santos, A. Figueiredo, Y. Choi, M. Silva, L. Sousa, F. Pessoa, M.
Sebastiana, B. Acioli, K. Palme, R. Malhó, M.S. Pais (2007) Genomic approaches
highlight the role played by sugars, auxins and polyamines during organogenic nodule
formation in hop. Poster apresentado no meeting “Botany & Plant Biology 2007”,
ASPBB, Chicago, 7-11 Julho 2007.
35. L. Marques, J. Banha, R. Malhó, D. Penque, L. Costa (2007)
Glycosylphosphatidylinositol-anchored Ceruloplasmin is Expressed in Human
Peripheral Blood Lymphocytes. European Iron Club Meeting 2007, London, 13-15
Setembro 2007
36. Ul-Rehman, C. Rato, R.M. Tunc-Ozdemir, R. Malhó, J.F. Harper (2010) Cyclic
nucleotide-gated channels CNGC7 and CNGC8 are required for pollen tube growth and
fertilization. Poster apresentado no “XXI International Congress on Sexual Plant
Reproduction”, Bristol, Agosto 2010.
37. A.F. Fernandes, F. Aresta-Branco, L. Cyrne, R. Malhó, R.F.M. Almeida, F.
Antunes, H.
S. Marinho (2010) Absence of sphingolipid 2-hydroxy-fatty acids promotes yeast
plasma membrane domain reorganization during adaptation to hydrogen peroxide.
Poster apresentado no XVII Congresso Nacional de Bioquímica, Dez2010, Porto.
38. R. Malhó, S. Serrazina, F. Vaz Dias (2011) Characterization of phosphatidylinositol
kinases in Arabidopsis pollen tube growth - a role in endocytosis and membrane
secretion. Poster apresentado no “Glasgow 2011 Soc. Exptl. Biology meeting”,
Glasgow, 1-4 Julho 2011.
39. S. Serrazina, F. Vaz Dias, R. Malhó (2011) Characterization of FAB1
phosphatidylinositol kinases in Arabidopsis pollen tube growth and fertilization. Poster
apresentado no “Glasgow 2011 Soc. Exptl. Biology meeting”, Glasgow, 1-4 Julho
2011.
40. L. Saavedra, R. Catarino, T. Heinz, I. Heilmann, M. Bezanilla, R. Malhó (2013)
Towards understanding the role of PTEN genes in the moss Physcomitrella patens.
Poster apresentado no “16th Intl Moss Conference”, Praga, 17-19 Junho 2013.
41. S. Serrazina, F. Vaz Dias, R. Malhó (2013) Characterization of FAB1
phosphatidylinositol kinases in Arabidopsis pollen tube growth and fertilization.
Comunicação apresentada no “Annual Meeting of the Soc Exptl Biology - SEB”
Valência, Espanha, 2-6 Julho.
42. L. Saavedra, R. Catarino, T. Heinz, I. Heilmann, M. Bezanilla, R. Malhó (2013)
Towards understanding the role of PTEN genes in the moss P. patens. Poster
apresentado no “Annual Meeting of the Soc Exptl Biology - SEB” Valência, Espanha,
2-6 Julho.
43. F. Vaz Dias, S. Serrazina, R. Malhó (2013) The role of Arabidopsis thaliana
diacylglycerol kinase 4, in pollen tube growth and fertilization; a preliminary approach.
Poster apresentado no “Annual Meeting of the Soc Exptl Biology - SEB” Valência,
Espanha, 2-6 Julho.
44. L. Saavedra, R. Catarino, R. Malhó (2014) Phosphatase and tensin homolog
(PTEN)
is a growth repressor of both rhizoid and gametophore development in the moss
Physcomitrella patens. Poster apresentado no New Phytologist NGS, Norwich, UK, 2930 Julho.
11. Línguas
Língua
Inglês
Francês
Leitura
Excelente
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Escrita
Excelente
Elementar
Conversação
Excelente
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