Oncobiology 2015
The structure of the module:
This module (23th March – 2nd April) has a dual structure: lectures and seminars,
and work on research projects. The Oncobiology module this year includes also
the “Late 25th anniversary Symposium of Ipatimup” on the 25th March with the
Special session on the 2014 MJB Award to David Lyden.
The aims of the module:
The Oncobiology module will have sessions to discuss biological/molecular
mechanisms of cancer development and progression. Sessions will include
discussion of clinical cases followed by open discussions with the students about
the underlying etiological factors, the biological pathways and molecular
mechanisms underlying pathological lesions. The sessions will include:
1- Presentation of clinical cases (sporadic and hereditary)
2- Pathological aspects of the tumours
3- Etiology and molecular basis of the disease
Teaching staff: Senior Researchers of IPATIMUP and from the Medical Faculty,
and Post-docs.
23 March
Morning:
9.00-9.30 - Documents and structure of the module (Participants: R Seruca
and Celso Reis)
9:30.10:00- Distribution of the projects (Raquel Seruca and Celso Reis, with
the collaboration of Paula Soares, Carla Oliveira, Raquel Almeida, José
Carlos Machado).
10:30 – 12:00 Projects preparation/discussion
Afternoon:
15.00-17:30 - Cancer genes: Beyond the classic dual division (Participant: M
Sobrinho-Simões)
17.30-19.00 – Projects preparation/discussion.
24 March
Morning:
9.30-12.00 – Oncogenes and Tumor suppressor genes
(Participants: Raquel Seruca)
Afternoon:
14.30-17.00 – Metabolism and cancer
(Participants: Valdemar Máximo, Jorge Lima, M Sobrinho-Simões).
17.30-19.00 – Projects preparation/discussion.
25 March (Auditorium)
Late 25the anniversary Symposium of Ipatimup: “Understand cancer as
a systemic disease: cancer is not just the tumour”
9:30
Opening/Welcome – Maria de Sousa and Manuel Sobrinho Simões
9:45 Mina Bissell – Lecture:
Why don't we get more cancer?: Because half the secret of the cell is
outside the cell!
10:45 Coffee break
11:15 David Lyden – Lecture
What are exosomes and how are they are changing our concepts of cancer
and metastasis.
12:00 General discussion
12:30 Special session: The 2014 MJB Award to David Lyden.
13:00 Closing remarks – Celso Reis and Raquel Seruca
Afternoon:
15.30-18.00 – Genetic dynamics of cancer cells
(Participants: José Carlos Machado, José Luís Costa, Sónia Melo)
18.00-19.00 – Projects preparation/discussion.
26 March
Morning:
9.00-10:30 - Students meeting with David Lyden and Mina Bissel
10.30-13.00 – Tumor Growth and Immortalization
(Participants: Paula Soares, João Vinagre, Ana Preto
Afternoon:
14.30–19.00 – Projects preparation/discussion.
27 March
Morning:
9.30-12.00 – Infection and cancer: “the example of Helicobacter pylori and
gastric carcinoma"
(Participants: Céu Figueiredo, Marina Leite, Rui Ferreira)
Afternoon:
14.30–17.00 – Cell and tissue differentiation
(Participants: Raquel Almeida, Leonor David, Rita Barros)
17.30-19.00 – Projects preparation/discussion
30 March
Morning:
9.30-12.00 – Glycosylation in cancer.
(Participants: Celso Reis, Salomé Pinho, Ana Magalhães)
Afternoon:
14.30-16.00 – Cancer Stem Cells
(Participant: Joana Paredes)
17.00-19.00 – Projects preparation/discussion.
31 March
Morning:
9.30-12.00 – Cancer Cell invasion
(Participants: Raquel Seruca, Sérgia Velho, Fátima Carneiro)
Afternoon:
14.30-17.30 – Metastable phenotypes in Epithelial Cancer (Participants:
Carla Oliveira, Joana Paredes, Joana Carvalho)
17:30-19.00 – Projects preparation/discussion.
1 April
Morning:
9.00-10.30 – Proteomics applications in Cancer Research
(Participants: Celso Reis, Hugo Osório)
11:00-12:30 - DNA/RNAomics and Bioinformatics: applications in Cancer
(Participant: Carla Oliveira, Patrícia Oliveira)
Afternoon:
14.00-15.00 – Seminar: The CAM model in Cancer Research
(Participants: Marta T. Pinto)
15.30-19.00 – Projects preparation/discussion.
2 April
Morning:
9.30-11.30 – Cancer treatment and Drug resistance. (Participant: Helena
Vasconcelos; Gabriela Almeida)
Afternoon:
14.00 - 18.00 - Projects: presentations and general discussion.